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龙工作室

城市环境设计 2012年第9期 126-129页

龙工作室是一个拉长的微变形的盒体,它逐渐脱离地面,直到开始凌驾在一排高柱之上,将结构抬离地面,框视出北大西洋的海景,时有源于格陵兰冰川的冰山浮现。强劲粗犷的建筑个性发自对场所敏锐的共鸣。这是一种双重的个性,既是框出地景、大... 详细信息

龙工作室是一个拉长的微变形的盒体,它逐渐脱离地面,直到开始凌驾在一排高柱之上,将结构抬离地面,框视出北大西洋的海景,时有源于格陵兰冰川的冰山浮现。强劲粗犷的建筑个性发自对场所敏锐的共鸣。这是一种双重的个性,既是框出地景、大海与天上云朵的观景装置,也是艺术心灵在此独享宁静的场所——作

关键词：工作室场所窗框玻璃窗

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桥工作室

城市环境设计 2012年第9期 134-137页

从深湾宅(Deep Bay House)通往桥工作室的路径,从地图上看来很短。但考虑到地形,海岸线上一路壮美的岩石和花岗岩上长满的苔藓,现实就会是另外一种情形。桥工作室给人的第一印象是其抽象的特质。沿侧立面看去,它看起来像是一个无窗、木... 详细信息

从深湾宅(Deep Bay House)通往桥工作室的路径,从地图上看来很短。但考虑到地形,海岸线上一路壮美的岩石和花岗岩上长满的苔藓,现实就会是另外一种情形。桥工作室给人的第一印象是其抽象的特质。沿侧立面看去,它看起来像是一个无窗、木覆面的平行四边形。工作室凌驾于地景之上,支撑它的是四只柱墩,

关键词：工作室 Bay 平行四边形深湾侧立面 Studio

3D-printed facet-attached microlenses for advanced photonic system assembly

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Light(Advanced Manufacturing) 2023年第2期4卷 1-17页

作者： Yilin Xu pascal Maier Mareike Trappen philipp-Immanuel Dietrich Matthias Blaicher Rokas Jutas Achim Weber Torben Kind colin Dankwart Jens Stephan Andreas Steffan Amin Abbasi padraic Morrissey Kamil Gradkowski Brian Kelly peter O’Brien Wolfgang Freude Christian Koos Institute of photonics and Quantum Electronics(IpQ) Karlsruhe Institute of Technology(KIT)Engesserstr.576131 KarlsruheGermany Institute of Microstructure Technology(IMT) KITHermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany Vanguard Automation GmbH Gablonzer Strasse.1076185 KarlsruheGermany ficon TEC Service GmbH Im Finigen 328832 AchimGermany II-VI Inc. Reuchlinstraße 10/1110553 BerlinGermany photonics Research Group Ghent University-imecTechnologiepark-Zwijnaarde 126B-9052 GentBelgium Tyndall national Institute T12 R5CP CorkIreland Eblana photonics Ltd. West Pier Business Campus3 Old Dunleary RdDún LaoghaireDublinA96 A621Ireland

Wafer-level mass production of photonic integrated circuits(pIC)has become a technological mainstay in the field of optics and photonics,enabling many novel and disrupting a wide range of existing ***,scalable photonic packaging and system assembly still represents a major challenge that often hinders commercial adoption of pIC-based ***,chip-to-chip and fiber-to-chip connections often rely on so-called active alignment techniques,where the coupling efficiency is continuously measured and optimized during the assembly *** unavoidably leads to technically complex assembly processes and high cost,thereby eliminating most of the inherent scalability advantages of pIC-based *** this paper,we demonstrate that 3D-printed facet-attached microlenses(FaML)can overcome this problem by opening an attractive path towards highly scalable photonic system assembly,relying entirely on passive assembly techniques based on industry-standard machine vision and/or simple mechanical *** can be printed with high precision to the facets of optical components using multi-photon lithography,thereby offering the possibility to shape the emitted beams by freely designed refractive or reflective ***,the emitted beams can be collimated to a comparatively large diameter that is independent of the device-specific mode fields,thereby relaxing both axial and lateral alignment ***,the FaML concept allows to insert discrete optical elements such as optical isolators into the free-space beam paths between pIC *** show the viability and the versatility of the scheme in a series of selected experiments of high technical relevance,comprising pluggable fiber-chip interfaces,the combination of pIC with discrete micro-optical elements such as polarization beam splitters,as well as coupling with ultra-low back-reflection based on non-planar beam paths that only comprise tilted optical *** on our re

关键词： photonic integration photonic assembly photonic packaging Additive laser manufacturing Multi-photon lithography Facet-attached microlenses Optical alignment tolerances Fiber-chip coupling Hybrid multi-chip modules

养猪生产生命周期评估(LCA)专题(综述)(续完)

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国外畜牧学（猪与禽） 2017年第8期37卷 106-108页

作者：张江陈建康 Graham McAuliffe Deborah Chapman colin Sage 上海农林职业技术学院农生系

2．3粪便处理生命周期评估虽然研究表明饲料始终是家畜生产最大的环境压力，但在养殖地区，粪便处理是更大的问题，因为如果排泄物管理不善，n和p有可能流失进入淡水和地下水，nH，也存在酸化风险。可通过厌氧消化等技术减少直接施肥等... 详细信息

2．3粪便处理生命周期评估虽然研究表明饲料始终是家畜生产最大的环境压力，但在养殖地区，粪便处理是更大的问题，因为如果排泄物管理不善，n和p有可能流失进入淡水和地下水，nH，也存在酸化风险。可通过厌氧消化等技术减少直接施肥等传统处理方式带来的风险，同时沼气生产还可获得新效益。有效施肥也可减少化肥用量。LCA分析方法已经大量应用于猪粪分析。

关键词：生命周期评估养猪生产综述专题粪便处理环境压力家畜生产养殖地区

吡唑-4-基烷基酮衍生物的合成、结构和除草活性

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农药译丛 1993年第5期15卷 28-33,35页

作者： Helen G.McFadden colin H. L. Kennard 仲哲澳大利亚植物产业部澳大利亚昆士兰大学化学系

原卟啉原氧化酶(protox)最近被证实是已知光动力作用除草剂化合物的靶标。如许多其他除草剂的结合位置一样,原卟啉原氧化酶是几种化学结构上三级交叉类型的除草剂(图1)的酶靶标,包括二苯基醚类[如乙氧氟草醚(Oxyfluorfen),Ⅰa;三氟羧草... 详细信息

原卟啉原氧化酶(protox)最近被证实是已知光动力作用除草剂化合物的靶标。如许多其他除草剂的结合位置一样,原卟啉原氧化酶是几种化学结构上三级交叉类型的除草剂(图1)的酶靶标,包括二苯基醚类[如乙氧氟草醚(Oxyfluorfen),Ⅰa;三氟羧草醚(acifluorfen),Ⅰb]、噁二唑类[如噁草酮(Oxadiazon)、吡啶衍生物类(如LS82-556,(S)-2,6-二甲基-n-(α-甲基苄基)-5-丙酰基烟酰胺];吡唑-4-腈类[如M&B39279,5-氨基-1-(2,6-二氯-4-三氟甲基)苯基吡唑-4-腈,Ⅱa]和推测可能是吡唑-4-腈的类似物(如Ⅲa,表1)。

关键词：酮类吡唑除草剂农药活性合成

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热的氧化板片限制了地表氮进入地幔的效率

矿物岩石地球化学通报 2021年第2期40卷 336-336页

作者：夏群科(编译) colin Jackson Elizabeth Cottrell Ben Andrews 不详

n是生命和气候的关键元素。根据地质样品记录的大气成分信息,30亿年以来大气中的氮气(n2)含量一直保持在较高水平。因此,俯冲沉积物中大量的n应该不能有效进入地幔,否则会造成大气中的n在地质时间尺度的快速降低。另外,俯冲带中的n也可... 详细信息

n是生命和气候的关键元素。根据地质样品记录的大气成分信息,30亿年以来大气中的氮气(n2)含量一直保持在较高水平。因此,俯冲沉积物中大量的n应该不能有效进入地幔,否则会造成大气中的n在地质时间尺度的快速降低。另外,俯冲带中的n也可能以nH+4等形式在矿物、熔体和流体中赋存,而n在不同载体之间的分配系数缺乏制约,导致目前无法判断是哪些因素决定了俯冲带中n的命运。

关键词：大气成分时间尺度俯冲带地质样品分配系数关键元素地幔沉积物

First radiative shock experiments on the SG-II laser

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High power Laser Science and Engineering 2021年第2期9卷 193-200页

作者： Francisco Suzuki-Vidal Thomas Clayson Chantal Stehlé Uddhab Chaulagain Jack W.D.Halliday Mingying Sun Lei Ren ning Kang Huiya Liu Baoqiang Zhu Jianqiang Zhu Carolina De Almeida Rossi Teodora Mihailescu pedro Velarde Manuel Cotelo John M.Foster colin n.Danson Christopher Spindloe Jeremy p.Chittenden Carolyn Kuranz Blackett Laboratory Imperial College LondonLondonUK First Light Fusion Ltd YarntonUK LERMA Sorbonne-UniversitéObservatoire de ParisCNRSFrance ELI Beamlines Center Institute of PhysicsCzech Academy of SciencesDolni BrezanyCzech Republic Shanghai Institute of Optics and Fine Mechanics Chinese Academy of SciencesShanghaiChina Instituto de Fusión nuclear Guillermo Velarde Universidad Politécnica de MadridMadridSpain AWE plc. AldermastonReadingUK Science and Technology Facilities Council Rutherford Appleton LaboratoryHarwell CampusChiltonDidcotUK University of Michigan Ann ArborMIUSA Current affiliation:Magdrive Ltd HarwellUK

We report on the design and first results from experiments looking at the formation of radiative shocks on the ShenguangII(SG-II)laser at the Shanghai Institute of Optics and Fine Mechanics in ***-heating of a two-layer CH/CH–Br foil drives a∼40 km/s shock inside a gas cell filled with argon at an initial pressure of 1 *** use of gas-cell targets with large(several millimetres)lateral and axial extent allows the shock to propagate freely without any wall interactions,and permits a large field of view to image single and colliding counter-propagating shocks with time-resolved,pointprojection X-ray backlighting(∼20µm source size,4.3 keV photon energy).Single shocks were imaged up to 100 ns after the onset of the laser drive,allowing to probe the growth of spatial nonuniformities in the shock *** results are compared with experiments looking at counter-propagating shocks,showing a symmetric drive that leads to a collision and stagnation from∼40 ns *** present a preliminary comparison with numerical simulations with the radiation hydrodynamics code ARWEn,which provides expected plasma parameters for the design of future experiments in this facility.

关键词： high energy density physics laboratory astrophysics plasma physics high-power laser laser-driven shocks experiments X-ray backlighting X-ray radiography

Sensitive detection of HIV-1 resistance to Zidovudine and impact on treatment outcomes in low-to middle-income countries

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Infectious Diseases of poverty 2017年第1期6卷 1449-1461页

作者： Richard M.Gibson Gabrielle nickel Michael Crawford Fred Kyeyune colin Venner Immaculate nankya Eva nabulime Emmanuel ndashimye Art F.Y.poon Robert A.Salata Cissy Kityo peter Mugyenyi Miguel E.Quinones-Mateu Eric J.Arts Department of Microbiology and Immunology University of Western Ontario1151 Richmond St.Dental Sciences Bldg.Rm 3014LondonOntario N6A 5C1Canada Division of Infectious Diseases Department of MedicineCase Western Reserve UniversityClevelandOHUSA Department of Molecular Biology and Microbiology Case Western Reserve UniversityClevelandOHUSA Department of pathology Case Western Reserve UniversityClevelandOHUSA Center for AIDS Research Uganda Laboratories Joint Clinical Research CentreKampalaUganda Department of pathology and Laboratory Medicine University of Western OntarioKampalaUganda TREAT Joint Clinical Research CentreKampalaUganda

Background:Thymidine analogs,namely AZT(Zidovudine or Retrovir^(TM))and d4T(Stavudine or Zerit^(TM))are antiretroviral drugs still employed in over 75%of first line combination antiretroviral therapy(cART)in Kampala,Uganda despite aversion to prescribing these drugs for cART in high income countries due in part to adverse *** this study,we explored how the continued use of these thymidine analogs in cART could impact emergence of drug resistance and impact on future treatment success in Uganda,a low-income ***:We examined the drug resistance genotypes by Sanger sequencing of 262 HIV-infected patients failing a first line combined antiretroviral treatment containing either AZT or d4T,which represents approximately 5%of the patients at the Joint Clinical Research Center receiving a AZT or d4T containing *** generation sequencing(DEEpGEn^(TM)HIV)and multiplex oligonucleotide ligation assays(AfripOLA)were then performed on a subset of patient samples to detect low frequency drug resistant ***4 cell counts,viral RnA loads,and treatment changes were analyzed in a cohort of treatment success and ***:Over 80%of patients failing first line AZT/d4T-containing cART had predicted drug resistance to 3TC(Lamivudine)and non-nucleoside RT inhibitors(nnRTIs)in the treatment regimen but only 45%had resistance AZT/d4T associated resistance mutations(TAMs).TAMs were however detected at low frequency within the patients HIV quasispecies(1-20%)in 21 of 34 individuals who were failing first-line AZT-containing cART and lacked TAMs by *** to lack of TAMs by Sanger,AZT was typically maintained in second-line therapies and these patients had a low frequency of subsequent virologic ***:Our findings suggest that continued use of AZT and d4T in first-line treatment in low-to-middle income countries may lead to misdiagnosis of HIV-1 drug resistance and possibly enhance a succession of second-and third-line treatment failu

关键词： Antiretroviral treatment Drug resistance Uganda

A history of high-power laser research and development in the United Kingdom

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High power Laser Science and Engineering 2021年第2期9卷 41-126页

作者： colin n.Danson Malcolm White John R.M.Barr Thomas Bett peter Blyth David Bowley Ceri Brenner Robert J.Collins neal Croxford A.E.Bucker Dangor Laurence Devereux peter E.Dyer Anthony Dymoke-Bradshaw Christopher B.Edwards paul Ewart Allister I.Ferguson John M.Girkin Denis R.Hall David C.Hanna Wayne Harris David I.Hillier Christopher J.Hooker Simon M.Hooker nicholas Hopps Janet Hull David Hunt Dino A.Jaroszynski Mark Kempenaars Helmut Kessler Sir peter L.Knight Steve Knight Adrian Knowles Ciaran L.S.Lewis Ken S.Lipton Abby Littlechild John Littlechild peter Maggs Graeme p.A.Malcolm OBE Stuart p.D.Mangles William Martin paul McKenna Richard O.Moore Clive Morrison Zulfikar najmudin David neely Geoff H.C.new Michael J.norman Ted paine Anthony W.parker Rory R.penman Geoff J.pert Chris pietraszewski Andrew Randewich nadeem H.Rizvi nigel Seddon MBE Zheng-Ming Sheng David Slater Roland A.Smith Christopher Spindloe Roy Taylor Gary Thomas John W.G.Tisch Justin S.Wark colin Webb S.Mark Wiggins Dave Willford Trevor Winstone AWE Aldermaston ReadingUK Oxford Centre for High Energy Density Science Department of PhysicsClarendon LaboratoryUniversity of OxfordOxfordUK Centre for Intertial Fusion Studies Blackett LaboratoryImperial College LondonLondonUK Formerly of Electrox LetchworthUK Formerly of Central Laser Facility Rutherford LaboratoryDidcotUK Formerly of Ferranti Defence Systems LincolnUK Leonardo EdinburghUK Retired AWEReadingUK Formerly of AWE ReadingUK Formerly of Laser Lines Ltd BanburyUK Formerly of Optilas Ltd Milton KeynesUK Retired Pro-Lite TechnologyCranfieldUK Specialised Imaging Ltd PitstoneUK Central Laser Facility STFC Rutherford Appleton LaboratoryDidcotUK Magna-power Electronics Ltd ReadingUK DeBe Lasers Needham Laser TechnologiesWhitchurchUK Blackett Laboratory Imperial College LondonLondonUK SpIE Europe CardiffUK professor Emeritus(physics) University of HullKingston upon HullUK Kentech Instruments Ltd WallingfordUK Department of physics Clarendon LaboratoryUniversity of OxfordOxfordUK professor Emeritus Department of PhysicsUniversity of StrathclydeGlasgowUK Department of physics Durham UniversityDurhamUK professor Emeritus(photonics) Heriot-Watt UniversityEdinburghUK professor Emeritus University of SouthamptonSouthamptonUK Optical Surfaces Ltd KenleyUK JEH Lasers Ltd RugbyUK Scottish Universities physics Alliance Department of PhysicsUniversity of StrathclydeGlasgowUK ITER Organization Saint-Paul-lez-DuranceFrance Manx precision Optics Ltd BallasallaUK Laser Lines Ltd BanburyUK Elliot Scientific Ltd MetroTest Scientific GroupHarpendenUK Centre for plasma physics Queen’s University BelfastBelfastUK Retired Founderand former MDRofin-Sinar UK LtdHullUK Heraeus noblelight Ltd CambridgeUK Mirli Books ChelmsfordUK M Squared Lasers Ltd GlasgowUK University of Hertfordshire HatfieldUK E&EO UK Ltd Barton-upon-HumberUK Department of physics University of YorkYorkUK IC Optical Systems Ltd BeckenhamUK Laser Micromachining Ltd St AsaphUK MBDA UK Ltd Brist

The first demonstration of laser action in ruby was made in 1960 by *** of Hughes Research Laboratories,*** laboratories worldwide began the search for lasers using different materials,operating at different *** the UK,academia,industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of *** historical review looks at the contribution the UK has made to the advancement of the technology,the development of systems and components and their exploitation over the last 60 years.

关键词： high-power lasers history United Kingdom