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Determining the level of extra-pair paternity in yellow-bellied prinias,a socially monogamous passerine

Zoological Research 2021年第1期42卷 108-115页

作者： Zhi-Feng Ding chun-lan zhang Wen-Sui zhang Qian-Min Yuan Long-Wu Wang Gang Ren En Li Hui-Jian Hu Wei Liang Guangdong Key Laboratory of Animal Conservation and Resource Utilization Guangdong Public Laboratory of Wild Animal Conservation and UtilizationInstitute of ZoologyGuangdong Academy of SciencesGuangzhouGuangdong 510260China State Forestry Administration of China Key Laboratory for Biodiversity Conservation in Mountainous Areas of Southwest Karst School of Life SciencesGuizhou Normal UniversityGuiyangGuizhou 550001China College of Life Sciences Anhui Normal UniversityWuhuAnhui 241000China Ministry of Education Key Laboratory for Ecology of Tropical Islands College of Life SciencesHainan Normal UniversityHaikouHainan 571158China

DEAR EDITOR,Previous work based on molecular evidence has shown that most socially monogamous birds follow a genetic polyandrous mating ***,our knowledge about avian mating systems is heavily biased toward the north temperate zone,with data on tropical birds remaining relatively *** uneven distribution of both phylogenetic and spatial sampling has hampered our understanding and interpretation of *** this study,we investigated the frequency of extra-pair paternity(EPP)in a tropical population of yellow-bellied prinias(Prinia flaviventris)in Guangxi,southern China.A total of 129 individuals belonging to 24 nests were sampled,among which 12 out of 83 chicks(14.46%)in seven nests were found to be EPP *** nests in which all nestlings were sampled,only five out of 56 chicks were EPP offspring,accounting for an unbiased EPP rate of 8.93%.This rate is below the average rate of EPP in the family *** possible causes of EPP in prinias and the occurrence of EPP in birds with high resource investment and intensive parental care are *** study highlights the value of genome-wide markers in determining relatedness in a wild bird species without a reference genome.

关键词： EPP EDIT yellow

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Enteral fistula as initial manifestation of primary intestinal lymphoma

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Chinese Medical Journal 2020年第1期133卷 101-102页

作者： Rui-Jie Zhao chun-lan zhang Yan zhang Xi-Yu Sun Yue-Hui Ni Ya-Ping Luo Ji Li Jia-Ming Qian Departm ent of Gastroenterology Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China Department of Hematology West China HospitalChengduSichuan 610047China Department of Hematology Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China Department of General Surgery Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China Department of Internal Medicine Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China Department of Nuclear Medicine Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China

To the Editor:Enteral fistula(EF)is a rare complication mostly caused by inflammatory bowel disease and in some cases by duodenal ulcer,intestinal tuberculosis,intestinal lymphoma,abdominal surgery,or necrotizing enterocolitis.[1,2]Perforative complications including perforation and EF are major complications of primary intestinal lymphoma(PIL).Vaidya et al[2]reported that in a cohort of 1062 patients with gastrointestinal lymphoma,bowel perforation occurred in 9%of the patients,and among them,the small intestine was the most common site(81%).Furthermore,perforation events occurred as the initial presentation in 51%of these patients.

关键词： lymphoma fistula intestine

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Comprehensive Evaluation on Consumption Structure of Rural Residents with Principal Component Analysis in China

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Asian Agricultural Research 2011年第3期3卷 96-97,100页

作者： GUAN Lin,LI chun-lan,zhang Bo School of Science,Hebei Agricultural University,Baoding 071000,China

In order to make analysis on consumption structure of rural residents,the paper makes a principle component analysis on consumption expenditure per capita of rural residents in different areas of 2009 based on statistics of China statistical yearbook of *** a principal component,the paper arranges 31 provinces in China in *** lists the 1st place with highest marks;coastal provinces in southeastern part,the Northeast,Beijing and Tianjin are at the top;the northern and central parts with Hebei,Shanxi,Hubei as representatives scores minus which is a little lower than that of average;the western part,such as Guizhou,Xizang,Gansu and so on are in far *** paper also makes analysis on the consumption structure of rural residents and proposes suggestions on how to accelerate consumption of rural residents.

关键词： Rural residents Consumption Principal component an

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Gut microbiota-astrocyte axis: new insights into age-related cognitive decline

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Neural Regeneration Research 2025年第4期20卷 990-1008页

作者： lan zhang Jingge Wei Xilei Liu Dai Li Xiaoqi Pang Fanglian Chen Hailong Cao Ping Lei Haihe Laboratory of Cell Ecosystem Department of GeriatricsTianjin Medical University General HospitalTianjinChina Tianjin Geriatrics Institute Tianjin Medical University General HospitalTianjinChina Department of Gastroenterology and Hepatology Tianjin Medical University General HospitalNational Key Clinical SpecialtyTianjin Institute of Digestive DiseasesTianjin Key Laboratory of Digestive DiseasesTianjinChina Department of Urology Tianjin Medical University General HospitalTianjinChina Tianjin Neurological Institution Tianjin Medical University General HospitalTianjinChina

With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent *** is considered the main risk factor for cognitive decline and acts through alterations in the composition of the gut microbiota,microbial metabolites,and the functions of *** microbiota–gut–brain axis has been the focus of multiple studies and is closely associated with cognitive *** article provides a comprehensive review of the specific changes that occur in the composition of the gut microbiota and microbial metabolites in older individuals and discusses how the aging of astrocytes and reactive astrocytosis are closely related to age-related cognitive decline and neurodegenerative *** article also summarizes the gut microbiota components that affect astrocyte function,mainly through the vagus nerve,immune responses,circadian rhythms,and microbial ***,this article summarizes the mechanism by which the gut microbiota–astrocyte axis plays a role in Alzheimer’s and Parkinson’s *** findings have revealed the critical role of the microbiota–astrocyte axis in age-related cognitive decline,aiding in a deeper understanding of potential gut microbiome-based adjuvant therapy strategies for this condition.

关键词： age aging Alzheimer’s disease astrocytes cognitive decline dementia gut microbiota gut–brain axis microbial metabolites neuroinflammation Parkinson’s disease

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Deciphering Water Oxidation Catalysts:The Dominant Role of Surface Chemistry over Reconstruction Degree in Activity Promotion

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Nano-Micro Letters 2025年第3期17卷 340-354页

作者： Li An Jianyi Li Yuanmiao Sun Jiamin Zhu Justin Zhu Yeow Seow Hong zhang Nan zhang Pinxian Xi * Zhichuan JXu chun‑Hua Yan State Key Laboratory of Applied Organic Chemistry Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu ProvinceFrontiers Science Center for Rare IsotopesCollege of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000People’s Republic of China School of Materials Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore Faculty of Materials Science and Energy Engineering Institute of Technology for Carbon NeutralityShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055People’s Republic of China Key Laboratory of Electromagnetic Materials and Devices National Center for International Research On Photoelectric and Energy MaterialsSchool of Materials and EnergyElectron Microscopy CenterYunnan UniversityKunming 650091People’s Republic of China State Key Laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive Utilization Baotou Research Institute of Rare EarthsBaotou 014030People’s Republic of China Beijing National Laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and ApplicationsPKU‑HKU Joint Laboratory in Rare Earth Materials and Bioinorganic ChemistryPeking UniversityBeijing 100871People’s Republic of China

Water splitting hinges crucially on the availability of electrocatalysts for the oxygen evolution *** surface reconstruction has been widely observed in perovskite catalysts,and the reconstruction degree has been often correlated with the activity ***,a systematic study on the roles of Fe substitution in activation of perovskite laniO_(3)is *** substituting Fe content influences both current change tendency and surface reconstruction ***_(0.9)Fe_(0.1)O_(3)is found exhibiting a volcano-peak intrinsic activity in both pristine and reconstructed among all substituted perovskites in the lani_(1-x)Fe_(x)O_(3)(x=0.00,0.10,0.25,0.50,0.75,1.00)*** reconstructed lani_(0.9)Fe_(0.1)O_(3)shows a higher intrinsic activity than most reported NiFe-based ***,density functional theory calculations reveal that Fe substitution can lower the O 2p level,which thus stabilize lattice oxygen in lani0.9Fe0.1O3 and ensure its long-term ***,it is vital interesting that activity of the reconstructed catalysts relied more on the surface chemistry rather than the reconstruction *** effect of Fe on the degree of surface reconstruction of the perovskite is decoupled from that on its activity enhancement after surface *** finding showcases the importance to customize the surface chemistry of reconstructed catalysts for water oxidation.

关键词： Oxygen evolution reaction Perovskite oxides Doping Activation and reconstruction

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The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting Li Wei zhang Jian Wu Hui Hong Wei Quan Xinyu Qiao chun Cui Chenmeng Qiao Weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

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草地早熟禾PpGA20ox1基因的克隆及表达分析

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中国草地学报 2017年第4期39卷 1-7页

作者：闫蒙举甘露何春艳张兰尹淑霞北京林业大学草坪研究所北京100083

利用RACE方法,从草地早熟禾叶片中克隆出1个GA20ox基因家族成员的cDNA序列,命名为PpGA20ox1,提交到Genbank,登录号为KX443595。PpGA20ox1开放阅读框长1095bp,编码含364个氨基酸的蛋白质序列;不含信号肽序列,为疏水蛋白,与黑麦草、小麦... 详细信息

利用RACE方法,从草地早熟禾叶片中克隆出1个GA20ox基因家族成员的cDNA序列,命名为PpGA20ox1,提交到Genbank,登录号为KX443595。PpGA20ox1开放阅读框长1095bp,编码含364个氨基酸的蛋白质序列;不含信号肽序列,为疏水蛋白,与黑麦草、小麦等物种的亲缘关系较近;用Gateway方法构建瞬时表达载体并注射烟草叶片观察亚细胞定位,发现其定位在细胞质和细胞核。用相对荧光定量qPCR方法研究基因的组织特异性及喷施赤霉素和烯效唑对基因表达的影响,结果表明PpGA20ox1基因在草地早熟禾叶片中表达量最高,根次之,叶鞘最少,且表达量受赤霉素和烯效唑抑制。

关键词：草地早熟禾 PpGA20ox1基因生物信息学亚细胞定位表达分析

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Physarum polycephalum-inspired adaptive optimization design of artificial microtubular networks

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Science China Chemistry 2025年

作者： Si-Min Zeng Di-Wei Zheng Ting Pan Xing-lan Ding Yun zhang Chi-Hui Yang Si-Xue Cheng Xian-Zheng zhang Key Laboratory of Biomedical Polymers of Ministry of Education&Department of Chemistry Wuhan University

Natural biological microtubular networks have undergone adaptive evolutionary selection and may offer viable solutions to design challenges in artificial microtubular networks. The plasmodium of the slime mold Physarum polycephalum(P. polycephalum) extends continuously to form a protoplasmic microtubular network structure, directly connecting food *** simulations revealed that the formation of this adaptive P. polycephalum microtubular network could be captured by a mathematical algorithm. Inspired by the P. polycephalum microtubular networks, we propose an adaptive optimization design method for artificial microtubular networks. Specifically, we utilized hydrogels with biodegradable and tissue-adhesive properties to replicate the P. polycephalum microtubular networks via photomask. In Rhodamine B diffusion and glucosecatalyzed reaction experiments, we found that the P. polycephalum microtubular networks exhibited significantly enhanced efficiency compared to vascular and artificial networks. Furthermore, we demonstrated the potential for uric acid(UA) degradation of the hydrogels with a real P. polycephalum microtubular network loaded with urate oxidase(UOx) in a rodent model of hyperuricemia. And this network achieved more than double the effect of the artificial network. This underscores the potential of natural microtubular networks to replace artificial microtubular networks.

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腐蚀管道剩余强度评价的基本方法

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四川大学学报（工程科学版） 2003年第5期35卷 50-54页

作者：王春兰张鹏陈利琼姚建军西南石油学院建筑工程学院四川成都新都610500

管道在长期的运行中不可避免会出现腐蚀,腐蚀缺陷的破裂是管道的主要失效形式。根据腐蚀管道的缺陷形貌将腐蚀分为均匀腐蚀、局部腐蚀和点蚀。采用双剪应力准则分析了腐蚀缺陷管道剩余强度的塑性极限承载能力,所建立的模型考虑了管道现... 详细信息

管道在长期的运行中不可避免会出现腐蚀,腐蚀缺陷的破裂是管道的主要失效形式。根据腐蚀管道的缺陷形貌将腐蚀分为均匀腐蚀、局部腐蚀和点蚀。采用双剪应力准则分析了腐蚀缺陷管道剩余强度的塑性极限承载能力,所建立的模型考虑了管道现场条件和室内爆破实验条件的差异,并提出了均匀腐蚀、局部腐蚀和点蚀管道剩余强度的分级评价方法和步骤,评价的精确性、评价所需数据资料的多少、评价人员的技能和完成评价分析的复杂性随级度的提高而增加。根据加拿大NOVA公司的爆破实验结果,可以验证该方法比美国ASMEB31G和API579所推荐的方法更为接近于工程实际。

关键词：管道剩余强度腐蚀缺陷分级评价

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The Citron homology domain of MAP4Ks improves outcomes of traumatic brain injury

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Neural Regeneration Research 2025年第11期20卷 3233-3244页

作者： Xiaoling Zhong Wenjiao Tai Meng-Lu Liu Shuaipeng Ma Tianjin Shen Yuhua Zou chun-Li zhang Department of Molecular Biology University of Texas Southwestern Medical CenterDallasTXUSA Hamon Center for Regenerative Science and Medicine University of Texas Southwestern Medical CenterDallasTXUSA Peter O’Donnell Jr.Brain Institute University of Texas Southwestern Medical CenterDallasTXUSA

The mitogen-activated protein kinase kinase kinase kinases(MAP4Ks)signaling pathway plays a pivotal role in axonal regrowth and neuronal degeneration following *** targeting this pathway is beneficial to brain injury remains *** this study,we showed that adeno-associated virus-delivery of the Citron homology domain of MAP4Ks effectively reduces traumatic brain injury-induced reactive gliosis,tauopathy,lesion size,and behavioral *** inhibition of MAP4Ks replicated the ameliorative effects observed with expression of the Citron homology ***,the Citron homology domain acted as a dominant-negative mutant,impeding MAP4K-mediated phosphorylation of the dishevelled proteins and thereby controlling the Wnt/β-catenin *** findings implicate a therapeutic potential of targeting MAP4Ks to alleviate the detrimental effects of traumatic brain injury.

关键词： adeno-associated virus Citron homology Citron homology domain gene therapy mitogen-activated protein kinase kinase kinase kinases traumatic brain injury

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