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Continuous Quantum Nondemolition Measurements of a Particle in Electromagnetic and Gravitational Fields

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Communications in Theoretical Physics 2005年第3X期44卷 455-458页

作者： zhu chun-hua zha chao-zheng Department of Physics Xinjiang University Wulumuqi 830046 China CCAST (World Laboratory) P.O. Box 8730 Beijing 100080 China

The detection of a particle in electromagnetic plus gravitational fields is investigated. We obtain a set of quantum nondemolition variables. The continuous measurements of these nondemolition parameters are analyzed in the framework of restricted path integral formalism. We manipulate the corresponding propagators, and deduce the probabilities associated with the possible measurement outputs.

关键词： continuous quantum nondemolition measurements restricted path integral

Diagnosis and treatment of pediatric anaplastic lymphoma kinasepositive large B-cell lymphoma:A case report

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World Journal of Clinical Cases 2021年第17期9卷 4268-4278页

作者： Meng zhang Ling Jin Yan-Long Duan Jing Yang Shuang huang Mei Jin Guang-hua zhu chao Gao Yi Liu Nan zhang chun-Ju Zhou Zi-Fen Gao Qin-Long zheng Dong Chen Yong-Hong zhang Beijing Key Laboratory of Pediatric Hematology Oncology National Discipline of PediatricsMinistry of EducationMOE Key Laboratory of Major Diseases in ChildrenHematology Oncology CenterBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China Department of Pathology Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China Department of Pathology Peking University Third HospitalBeijing 100 Laboratory of Molecular Diagnostics Department of Pathology and Laboratory MedicineBeijing Boren HospitalBeijing 100070China Division of Hematopathology Mayo ClinicRochesterMN 55905United States

BACKGROUND Anaplastic lymphoma kinase-positive(ALK+)large B-cell lymphoma(LBCL)is a rare type of lymphoma with high invasiveness and rapid *** occurs in all age groups,but is extremely rare in *** lesions mainly involve the lymph nodes and may present with extra-nodal *** to conventional chemotherapies and local radiotherapy is poor,with a 5-year overall survival of less than 40%.Recently,the use of ALK inhibitors for the treatment of this disease has been *** SUMMARY We present a case of a 12-year-old boy diagnosed with ALK+*** patient had a 2-mo medical history of a calvarial mass,extensive systemic involvement,and positive bone marrow clathrin heavy chain(CLTC)-ALK fusion *** remission 1(CR1)was achieved using the modified LMB89 Group C regimen followed by autologous stem cell *** patient relapsed 3 mo *** then achieved CR2 with three short courses of chemotherapy(COP,reduceddose ICE,low-dose Ara-c+VP16)and continuous alectinib targeted ***,allogeneic hematopoietic stem cell transplantation(allo-HSCT)was *** 16 mo after the allo-HSCT,the patient was still in *** The modified LMB89 Group C regimen and ALK inhibitors are ***-HSCT should be performed after remission.

关键词： Pediatric Anaplastic lymphoma kinase-positive large B-cell lymphoma CLTC-ALK PGS1-CLTC Hematopoietic stem cell transplantation Alectinib Case report

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南京地区下蜀黄土磁性地层年代与古环境变化

地层学杂志 2006年第2期30卷 116-123页

作者：武春林朱诚鹿化煜马春梅朱光耀郑朝贵许信旺南京大学城市与资源学系江苏南京210093 中国科学院地球环境研究所陕西西安710075 蚌埠学院人文与社会科学部安徽蚌埠233050 池州师范专科学校安徽池州247000

通过对南京江北泰山新村下蜀土剖面所采的144个样品和南京江南燕子矶下蜀土剖面所采的467个样品所进行的古地磁测年、磁化率测量和粒度测定,建立了南京地区下蜀黄土地层220kaB.P.以来较精细的时间标尺;在此工作基础上,将南京下蜀黄土堆... 详细信息

通过对南京江北泰山新村下蜀土剖面所采的144个样品和南京江南燕子矶下蜀土剖面所采的467个样品所进行的古地磁测年、磁化率测量和粒度测定,建立了南京地区下蜀黄土地层220kaB.P.以来较精细的时间标尺;在此工作基础上,将南京下蜀黄土堆积所记录的环境信息同北方经典黄土、深海沉积氧同位素记录进行了对比,发现燕子矶剖面磁化率曲线能够与深海沉积氧同位素曲线1—7阶段进行良好的对比,两者之间的细节变化具有一致性,其中S0表现为高值,可与氧同位素曲线阶段1对比,为一高温期;L1可以划分为两层黄土(L1LL1、L1LL2)和一层弱发育的古土壤(L1SS1),L1LL1和L1LL2可与阶段2和4对比,L1SS1可与阶段3对比;S1古土壤层由3个古土壤亚层(S1SS1、S1SS2、S1SS3)和2个弱成土亚层(S1LL1、S1LL2)叠置而成,磁化率曲线具有明显的三峰夹两谷形式,正好可与氧同位素阶段5对比,表明这一时期的古气候特点是在湿热的背景下有两次干冷波动,其中S1SS1、S1SS2、S1SS3分别对应于5a、5c、5e,S1LL1、S1LL2对应于5b、5d;L2黄土磁化率曲线整体呈谷形,但中下部有一次峰,下部磁化率偏高,与阶段6的曲线特征相吻合;S2古土壤层未见底,目前获得的磁化率曲线特征可与7a和7b对比。以上研究结果确立了江南风尘堆积的古气候全球变化意义。

关键词：下蜀黄土第四系古地磁年代学磁化率粒度古环境信息

南京江北地区晚更新世末期以来泥炭层δ^(13)C记录的古气候变化

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地理科学 2006年第3期26卷 328-334页

作者：郑朝贵朱诚高华中申洪源马春梅南京大学城市与资源学系

对南京江北地区林峰桥剖面晚更新世末期以来的两个泥炭层有机碳同位素测定结果表明,上部泥炭层和下部泥炭层1δ3C值皆较低(≤-23.79‰),部泥炭层的1δ3C值明显高于下部泥炭层。结合其它研究可知,该区全新世大暖期稳定暖湿鼎盛阶段的校... 详细信息

对南京江北地区林峰桥剖面晚更新世末期以来的两个泥炭层有机碳同位素测定结果表明,上部泥炭层和下部泥炭层1δ3C值皆较低(≤-23.79‰),部泥炭层的1δ3C值明显高于下部泥炭层。结合其它研究可知,该区全新世大暖期稳定暖湿鼎盛阶段的校正年代约在8.2~7.0 ka B.P.,在此阶段前后,表现为持续时间相对较短的低温气候环境。12.8~12.1 *** B.P.该区气温高低波动频繁期。12.8~12.7 *** B.P.和12.6~12.2ka B.P.两时段气温较低;2.7~12.6 *** B.P.阶段气温较高。12.2~12.1 *** B.P.表现为Younger D ryas之后气候的迅速增暖,可视为该区全新世开始的标志。

关键词：泥炭层 δ^13C 晚更新世气候变化南京江北地区

利用高密度电阻率法预测第四系浅层生物气——以江苏省南通地区为例

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天然气地球科学 2018年第5期29卷 719-728页

作者：滕龙殷启春方朝刚郑红军沈雪华朱红兵陈基炜中国科学技术大学地球和空间科学学院安徽合肥230026 中国地质调查局南京地质调查中心江苏南京210016

采用高密度电阻率法以改善浅层生物气的地球物理勘探效率,并以江苏省南通市海门—启东地区浅层生物气的探测结果为例,论述了高密度电阻率法在第四系岩性和层序结构划分、储层识别和气层预测等方面为应用。结果表明:以实测岩土物性为基础... 详细信息

采用高密度电阻率法以改善浅层生物气的地球物理勘探效率,并以江苏省南通市海门—启东地区浅层生物气的探测结果为例,论述了高密度电阻率法在第四系岩性和层序结构划分、储层识别和气层预测等方面为应用。结果表明:以实测岩土物性为基础,利用高密度电阻率法的二维反演视电阻率断面图,结合已知钻孔和静力触探信息可以较为详细地划分出南通地区第四系内150m以浅的地层结构。同时可以利用地层的电性特征识别研究区第四系浅层生物气储层并预测含气层:当砂体含气时,表现为高阻;当砂体无气而充水时,则为低阻。

关键词：高密度电阻率第四系生物气南通

Prognostic significance of regional lymphadenectomy in T1b gallbladder cancer:Results from 24 hospitals in China

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World Journal of Gastrointestinal Surgery 2021年第2期13卷 176-186页

作者： Tai Ren Yong-Sheng Li Xue-Yi Dang Yang Li Zi-Yu Shao Run-Fa Bao Yi-Jun Shu Xu-An Wang Wen-Guang Wu Xiang-Song Wu Mao-Lan Li Hong Cao Kun-hua Wang Hong-Yu Cai Chong Jin Hui-Han Jin Bo Yang Xiao-Qing Jiang Jian-Feng Gu Yun-Fu Cui Zai-Yang zhang chun-Fu zhu Bei Sun chao-Liu Dai Lin-Hui zheng Jing-Yu Cao Zhe-Wei Fei Chang-Jun Liu Bing Li Jun Liu Ye-Ben Qian Yi Wang Ya-Wei hua Xi zhang Chang Liu Wan-Yee Lau Ying-Bin Liu Department of General Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Shanghai Key Laboratory of Biliary Tract Disease Research Shanghai 200092China Department of Biliary-Pancreatic Surgery Renji Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200127China State Key Laboratory for Oncogenes and Related Genes Shanghai 200127China Department of General Surgery Shanxi Provincial Cancer HospitalTaiyuan 030013Shanxi ProvinceChina Department of GI Surgery China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Gastrointestinal and Hernia Surgery The First Affiliated Hospital of Kunming Medical UniversityKunming 650031Yunnan ProvinceChina Department of Hepatobiliary Surgery Nantong Tumor HospitalNantong 226361Jiangsu ProvinceChina Department of General Surgery Taizhou Municipal HospitalTaizhou 318000Jiangsu ProvinceChina Department of Hepatobiliary Surgery Wuxi Second People's HospitalWuxi 214002Jiangsu ProvinceChina Department of General Surgery The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325015Zhejiang ProvinceChina Department of Biliary Tract Surgery Second Military Medical UniversitySecondary Military Medical UniversityShanghai 200438China Department of General Surgery Changshu No.1 People’s Hospital Affiliated to Soochow UniversityChangshu 215500Jiangsu ProvinceChina Department of Hepatopancreatobiliary Surgery Second Affiliated Hospital of Harbin Medical UniversityHarbin 150086Heilongjiang ProvinceChina Department of General Surgery Shaoxing Second HospitalShaoxing 312000Zhejiang ProvinceChina Department of HPB Surgery Changzhou No.2 People’s HospitalChangzhou 213003Jiangsu ProvinceChina Department of Pancreatic and Biliary Surgery The First Affiliated Hospital of Harbin Medical UniversityHarbin 150009Heilongjiang ProvinceChina Department of Hepatobiliary Surgery Shengjing Hospital of China Medical UniversityShenyang 1

BACKGROUND Whether regional lymphadenectomy(RL)should be routinely performed in patients with T1b gallbladder cancer(GBC)remains a subject of *** To investigate whether RL can improve the prognosis of patients with T1b *** We studied a multicenter cohort of patients with T1b GBC who underwent surgery between 2008 and 2016 at 24 hospitals in 13 provinces in *** logrank test and Cox proportional hazards model were used to compare the overall survival(OS)of patients who underwent cholecystectomy(Ch)+RL and those who underwent Ch *** investigate whether combined hepatectomy(Hep)improved OS in T1b patients,we studied patients who underwent Ch+RL to compare the OS of patients who underwent combined Hep and patients who did *** Of the 121 patients(aged 61.9±10.1 years),77(63.6%)underwent Ch+RL,and 44(36.4%)underwent Ch ***(9.1%)patients in the Ch+RL group had lymph node *** 5-year OS rate was significantly higher in the Ch+RL group than in the Ch group(76.3%vs 56.8%,P=0.036).Multivariate analysis showed that Ch+RL was significantly associated with improved OS(hazard ratio:0.51;95%confidence interval:0.26-0.99).Among the 77 patients who underwent Ch+RL,no survival improvement was found in patients who underwent combined Hep(5-year OS rate:79.5%for combined Hep and 76.1%for no Hep;P=0.50).CONCLUSION T1b GBC patients who underwent Ch+RL had a better prognosis than those who underwent ***+Ch showed no improvement in prognosis in T1b GBC *** recommended by both the National Comprehensive Cancer Network and Chinese Medical Association guidelines,RL was only performed in 63.6%of T1b GBC *** Ch+RL should be advised in T1b GBC.

关键词： Gallbladder cancer Lymphadenectomy Hepatectomy Staging Prognosis Surgery

益骨胶囊含药血清对成骨细胞骨保护蛋白mRNA表达的影响

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中国临床康复 2005年第19期9卷 180-182页

作者：朱晓峰张荣华孙升云蔡宇郑仕富王廷春陈超李洁华广州暨南大学附属第一医院中医科广东省广州市510630 广州暨南大学药学院中药学教研室广东省广州市510630

目的:观察益骨胶囊含药血清对体外培养的大鼠成骨细胞骨保护蛋白mRNA的影响。方法:实验于2004-05/2005-02在广州暨南大学生命科学技术学院细胞与蛋白质工程实验室完成。选取12月龄SD雌性大鼠20只,随机分为2组。中药给药组(益骨胶囊由淫... 详细信息

目的:观察益骨胶囊含药血清对体外培养的大鼠成骨细胞骨保护蛋白mRNA的影响。方法:实验于2004-05/2005-02在广州暨南大学生命科学技术学院细胞与蛋白质工程实验室完成。选取12月龄SD雌性大鼠20只,随机分为2组。中药给药组(益骨胶囊由淫羊藿、当归、白芍、枸杞子等8味中药组成)和蒸馏水对照组,每组10只。运用大鼠灌胃的方法制备含药血清和对照血清,分离、培养新生大鼠的颅骨成骨细胞,传代后分为2组(含药血清组和空白血清对照组),每组8孔,分别在培养24,48h时用反转录聚合酶链反应技术测定特异性电泳条带所显示成骨细胞中骨保护蛋白mRNA的相对表达量,酶联免疫法检测48,72和96h时200mL/L终浓度培养上清中骨保护蛋白的浓度。结果:两组动物各10只,均无亡失,所取血清正常用于细胞培养。①成骨细胞在接种4h后可见部分细胞贴壁、伸展。随培养时间延长,细胞伸出较多突起,细胞形态为单核,多边形及梭形,培养2d细胞基本全部贴壁,主要为梭形或多边形,培养6d左右基本贴满瓶壁,呈铺路石样排列。单层铺满培养瓶后可出现重叠生长,传代细胞大约15d天左右开始形成矿化结节。②特异性电泳条带显示益骨胶囊含药血清培养后24h和48h成骨细胞骨保护蛋白mRNA的表达均高于空白血清对照组犤(0.196±0.015,0.236±0.016),(0.152±0.018,0.206±0.022),P<0.01犦;③200mL/L终浓度的益骨胶囊含药血清培养后48,72和96h成骨细胞骨保护蛋白的表达明显高于空白血清对照组犤(0.1230±0.0128,0.1681±0.0130,0.1983±0.0186),(0.1067±0.0106,0.1385±0.0126,0.1588±0.0121),P<0.01或P<0.05犦。结论:益骨胶囊含药血清具有促进成骨细胞表达骨保护蛋白的作用。提示益骨胶囊能够通过对成骨细胞的影响而对骨吸收环节具有抑制作用,但是否对其他信号通路也有作用尚待研究。

关键词：骨质疏松益骨胶囊/药理学成骨细胞

长江三峡地区全新世典型遗址与自然沉积剖面环境考古研究的意义

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地层学杂志 2017年第1期41卷 32-38页

作者：蔡天赦朱诚孙智彬郑朝贵马春梅朱光耀高华中南京大学地理与海洋科学学院江苏南京210046 四川省文物考古研究院四川成都610041 滁州学院地理信息与旅游学院安徽滁州239012 蚌埠学院淮河文化研究中心安徽蚌埠233030 临沂大学资源环境学院山东临沂276005

随着全球变化研究的不断深入,人类文明发展阶段的考古聚落遗址地层记录和全新世以来连续沉积的自然地层记录已得到国际学术界和各国科学家越来越多的关注。长江三峡地区有着丰富的全新世考古遗址资源,为新石器时代以来人类活动和环境变... 详细信息

随着全球变化研究的不断深入,人类文明发展阶段的考古聚落遗址地层记录和全新世以来连续沉积的自然地层记录已得到国际学术界和各国科学家越来越多的关注。长江三峡地区有着丰富的全新世考古遗址资源,为新石器时代以来人类活动和环境变化的环境考古研究提供了良好基础和条件。其中的中坝遗址具有厚度大、地层时代齐全完整、出土器物量多、并有大量种类繁多的脊椎动物骨骼(包括哺乳类、鸟类、鱼类、两栖类、爬行类)、测年材料和古洪水沉积地层现象丰富的特点;该区同时又有全新世以来自然连续沉积厚度达3m以上的大九湖泥炭沉积地层。对该区典型遗址和连续沉积的自然地层作比较研究,通过人类活动和环境演变的指标信息提取和时间序列的建立,可恢复该区全新世以来人类活动史、古洪水史,弄清人类活动和自然环境的关系及其对全球变化的响应,并建立三峡地区全新世以来标志性考古遗址地层剖面。

关键词：考古地层学环境考古考古遗址自然沉积剖面全新世长江三峡

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硅、磷配施对玉米氮钾养分吸收利用的影响

土壤通报 2015年第6期46卷 1489-1496页

作者：朱从桦谢孟林郭萍张嘉莉查丽孔凡磊袁继超四川农业大学农学院四川成都611130 农业部西南作物生理生态与耕作重点实验室四川成都611130

以耐低磷品种(正红2号)和低磷敏感品种(正红115)为材料,研究低磷土壤条件下,不同硅、磷肥料组合对玉米氮、钾吸收、利用及产量的影响。结果表明:耐低磷品种和低磷敏感品种成熟期植株氮和钾积累总量无显著差异,耐低磷品种籽粒氮积累总量... 详细信息

以耐低磷品种(正红2号)和低磷敏感品种(正红115)为材料,研究低磷土壤条件下,不同硅、磷肥料组合对玉米氮、钾吸收、利用及产量的影响。结果表明:耐低磷品种和低磷敏感品种成熟期植株氮和钾积累总量无显著差异,耐低磷品种籽粒氮积累总量、籽粒中氮分配比例和经济产量均显著高于低磷敏感品种,而耐低磷品种籽粒中钾积累量和籽粒中钾分配比例均明显低于低磷敏感品种。两个品种磷肥、硅肥以及硅、磷肥配施处理成熟期植株氮和钾积累总量、籽粒中氮和钾积累总量及经济产量均显著增加,表现出一定的硅、磷促氮钾的效应,而且还表现出一定硅磷协同作用;硅、磷配施处理灌浆结实期叶片氮转运量会降低,灌浆结实期茎叶钾素转运量会增加;耐低磷品种硅、磷配施处理籽粒中氮素分配比例增加不显著,籽粒中钾素分配比例显著增加,而低磷敏感品种硅、磷配施处理籽粒中氮素分配比例明显增加,籽粒中钾素分配比例增加不显著。综上所述,选择耐低磷品种并进行硅、磷肥配施能显著增加玉米生育前期对氮、钾养分的积累量,优化生育后期氮、钾的转运和分配比例,最终提高氮、钾利用效率及玉米产量。

关键词：磷肥硅肥氮钾积累利用产量