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产肠毒素大肠杆菌K88诱导仔猪炎症反应的分子机制

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中国畜牧兽医 2017年第1期44卷 262-267页

作者：李海花朱琪王世琼杨春蕾赵向华乔家运王文杰天津市畜牧兽医研究所天津300381 天津市畜禽健康养殖技术工程中心天津300381

为探讨产肠毒素大肠杆菌(ETEC)K88感染仔猪发生炎症反应的分子机制,试验用ETEC K88灌服断奶仔猪,ELISA法检测攻毒后仔猪血清中白细胞介素8(IL-8)含量,实时荧光定量PCR方法检测淋巴结中Toll样受体2(TLR2)、Toll样受体4(TLR4)及其信号通... 详细信息

为探讨产肠毒素大肠杆菌(ETEC)K88感染仔猪发生炎症反应的分子机制,试验用ETEC K88灌服断奶仔猪,ELISA法检测攻毒后仔猪血清中白细胞介素8(IL-8)含量,实时荧光定量PCR方法检测淋巴结中Toll样受体2(TLR2)、Toll样受体4(TLR4)及其信号通路相关基因(髓样分化因子88(MyD88)、Toll相互作用蛋白(Tollip)、B细胞淋巴瘤因子3(Bcl3))的mRNA相对表达水平。结果发现,仔猪攻毒ETEC K88后6和24h血清IL-8含量和淋巴结TLR2/4的表达水平均极显著或显著高于对照组(P0.05)。综上所述,ETEC K88感染仔猪可能是通过TLR2/4-MyD88信号通路产生炎症因子IL-8,促使仔猪出现炎症反应,且该炎症反应可能受Tollip和Bcl3蛋白的调控而被减弱。

关键词：大肠杆菌K88 仔猪炎症反应 Toll-样受体炎症调控

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烟台莱山新院病房动力分布式通风系统设计

建筑热能通风空调 2017年第4期36卷 94-98页

作者：樊燕唐艳滨王春雷付祥钊徐征中国建筑设计院有限公司重庆大学城市建设与环境工程学院

本文分析了医疗建筑中通风存在的新风量不足,空气品质低下的问题,指出了传统病房系统空调设计的问题,提出了动力分布式系统,该系统通过主风机和末端变风量模块的变速调节来实现新风按需供给,根据病房需求随时调整新风量,从而解决了新风... 详细信息

本文分析了医疗建筑中通风存在的新风量不足,空气品质低下的问题,指出了传统病房系统空调设计的问题,提出了动力分布式系统,该系统通过主风机和末端变风量模块的变速调节来实现新风按需供给,根据病房需求随时调整新风量,从而解决了新风量不足的问题。通过实际工程案例,分析了烟台莱山新院病房的动力分布式通风系统设计方法,提出了新风量的确定方法,明确了风系统设计和设备选型注意问题,找到了干管静压设定法进行系统控制。

关键词：新风量动力分布式通风系统干管静压设定法

Iron-catalyzed ketonization of 2-aryl-1,1-dibromoalkenes with KOAc:Synthesis of α-acetoxy aryl ketones via a Michael-like addition process

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Chinese Chemical Letters 2011年第5期22卷 571-574页

作者： Ming zhao chun xiang Kuang Xue Zhi Cheng Qing Yang Department of Chemistry Tongji University Shanghai 200092 China Department of Biochemistry School of Life Sciences Fudan University Shanghai 200433 China

A novel and convenient iron-catalyzed ketonization of 2-aryl-1,1-dibromoalkenes with KOAc has been achieved.A series ofα-acetoxy aryl ketones were prepared with moderate yields via 2-carbon position functionalization... 详细信息

关键词： Iron catalyst Ketonization Dibromoalkene α-Acetoxy ketone Potassium acetate

Modification mechanism of caking and coking properties of Shenmu subbituminous coal by low-temperature rapid pyrolysis treatment

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Journal of Iron and Steel Research International 2019年第10期26卷 1052-1060页

作者： xiang-chun Liu Bin Fang Zhi-gang zhao Rui-lun Xie zhao Lei Qiang Ling Ping Cui Anhui Key Laboratory of Coal Clean Conversion&Utilization School of Chemistry and Chemical EngineeringAnhui University of TechnologyMa'anshan 243032AnhuiChina

Shenmu(SM)subbituminous coal without caking property was treated by low-temperature rapid pyrolysis(LTRP)to modify its caking and coking *** treated samples were characterized by Fourier transform infrared spectrometry,vitrinite reflectance,and X-ray diffraction to determine the modification ***,caking index(G)and coking indices(mechanical strength,coke reactivity,and coke strength after reaction)were employed to evaluate caking and coking properties,*** results showed that SM coal was gradually upgraded with increasing processing ***,the G values for the treated samples were significantly higher than that for SM coal,and G reached the maximum value at 450℃,implying the modification of caking property and the existence of an optimum temperature(450℃).Additionally,laboratory coking determinations showed that LTRP increased the mechanical strength of coke and coke strength after reaction and decreased coke reactivity when the treated coals were used in the coal blends instead of raw SM ***,LTRP treatment is effective to improve the caking and coking properties of SM coal.A mechanism was proposed for the *** upgrading degree with suitable molecular masses and some releasable hydrogen-rich donor species present within the coal,which dominate the development of caking property,is important.

关键词： Caking property Coking property Non-caking coal Low-temperature rapid pyrolysis Subbituminous coal

Scheduling piece requests blindly and randomly for peer-to-peer live streaming

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The Journal of China Universities of Posts and Telecommunications 2010年第2期17卷 76-84页

作者： CHEN Yi-shuai CHEN Chang-jia zhao Yong-xiang LI chun-xi School of Electrical and Information Engineering Beijing Jiaotong University Beijing 100044 China

The design of piece scheduling algorithm is fundamental in mesh-based peer-to-peer （P2P） live streaming systems. This article regards the piece propagation process in P2P live streaming system as a conflict process, where peers compete to get the piece as soon as possible to meet the tight timing requirement of the live system. In this vision, the authors reduce the piece scheduling problem as a conflict resolution problem, and propose a blind random scheduling method to resolve it. The algorithm can be described as： 1） pieces are scheduled independently; 2） conflicts are resolved by the random back off algorithm. The theoretical analysis and simulation results prove that the algorithm scales well with the network size, and can obtain near-optimal in-time delivery of pieces. The algorithm is also easy to implement in the real-world system.

关键词： peer-to-peer live streaming conflict resolution exponential back off piece scheduling

iTRAQ-based quantitative proteome characterization of wheat grains during filling stages

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Journal of Integrative Agriculture 2017年第10期16卷 2156-2167页

作者： CUI Yong YANG Ming-ming DONG Jian zhao Wan-chun GAO xiang College of Agronomy Northwest A&F University Yangling 712100 P.R.China Wheat Engineering Research Center of Shaanxi Province Yangling 712100 P.R. China

Using isobaric tags for relative and absolute quantification （iTRAQ） and associated analytic technologies, we have cataloged and compared 7 069 unique wheat proteins expressed during four substages of the filling stage. Among them, 859 are differentially expressed, showing at least a 2-fold difference in concentration across substages. Differentially expressed proteins （DEPs） includind high-molecular weight giutenin subunit （W5AIU1）, low-molecular weight glutenin subunit （QSW3V4）, gliadin/avenin-like seed protein （D2KFG9）, and avenin-like protein （W5DVL2）, all of which have previously been identified as important for nutritional quality and bread-making properties, and all of which were found to increase at the latter stages of development. We have applied statistical techniques to group the proteins into hierarchical clusters, and have consulted databases to infer functional and other relationships among the identified proteins.

关键词： wheat proteome isobaric tags for relative and absolute quantification (iTRAQ) grain filling

Apple SINA11-JAZ2 module is involved in jasmonate signaling response

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Journal of Integrative Plant Biology 2024年第7期66卷 1270-1273页

作者： Di Ai Lei zhao chun-xiang You Yuepeng Han Jian-Ping An State Key Laboratory of Plant Diversity and Specialty Crops CAS Key Laboratory of Plant Germplasm Enhancement and Specialty AgricultureWuhan Botanical Garden of Chinese Academy of SciencesWuhan 430074China Hubei Hongshan Laboratory Wuhan 430070China University of Chinese Academy of Sciences Beijing 100049China Apple Technology Innovation Center of Shandong Province College of Horticulture Science and EngineeringShandong Agricultural UniversityTai-An 271018China

Jasmonic acid(JA)is an important phytolipid hormone involved in regulating many processes of plant growth and development,and plays a key role in plant resistance to biotic and abiotic *** the first discovery of methy... 详细信息

关键词： nat Apple involv

Delineation and Scale Effect of Precision Agriculture Management Zones Using Yield Monitor Data Over Four Years

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Agricultural Sciences in China 2007年第2期6卷 180-188页

作者： LI xiang PAN Yu-chun GE Zhong-qiang zhao chun-jiang National Engineering Research Center for Information Technology in Agriculture Beijing 100089 P.R. China Henan Information Industry Department Zhengzhou 450008 P.R.China Resource and Environment College Beijing Forestry University Beijing 100083 P.R.China

In this study, precision agriculture management zones were delineated using yield data over four years from the combine harvester equipped with yield monitor and DGPS receiver. Relative yields measured during each year were interpolated to 4 m2 grid size using ordinary kriging. The resultant interpolated yield maps were averaged across years to create a map of the mean relative yield, which was then used for cluster analysis. The mean yield map of post-classification was processed by applying majority filtering with window sizes that were equivalent to the grid sizes of 12, 20, 28, 36, 44, 52 and 60 m. The scale effect of management zones was evaluated using relative variance reduction, test of significant differences of the means of yield zones, spatial fragmentation, and spatial agreement. The results showed that the post-classification majority filtering （PCMF） eliminated lots of isolated cells or patches caused by random variation while preserving yield means, high variance reduction, general yield patterns, and high spatial agreement. The zoned result can be used as yield goal map for preplant or in-season fertilizer recommendation in precision agriculture.

关键词： precision agriculture management zone PCMF scale effect

Local Bifurcation of Critical Periods for a Class of Liénard Equations

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Acta Mathematicae Applicatae Sinica 2014年第3期30卷 627-634页

作者： Yi SHAO chun-xiang A School of Mathematics and Statistics Zhaoqing University

In this paper, we study the local bifurcation of critical periods near the nondegenerate center （the origin） of a class of Li@nard equations with degree 2n, and prove that at most 2n - 2 critical periods （taken into account multiplicity） can be produced from a weak center of finite order. We also prove that it can have exactly 2n - 2 critical periods near the origin.

关键词： period function critical periods local bifurcation