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Transurethral microwave thermotherapy treat chronic prostatitis

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Chinese Journal of Biomedical Engineering(English Edition) 1999年第1期8卷 26-27页

作者： liu Jun sheng department of urology,2nd hospital of shanxi medical university,taiyuan 030001,china

We have treated 26 chronic prostatitis patients with transurethral microwave *** 1 month treated,patients were followed *** results show that the relative voiding resistance (RVR) are significantly decreased than that before treated( P <0.01).Most of the subjective symptom are *** way of transurethral microwave thermotherapy is most effect to treat chronic *** we discussed the etiology and the machnism of thermotherapy.

关键词： microwave chronic prostatitis relative voiding resistance (RVR)

Transgenic mice designed to express human α-1,2-fucosyltransferase in combination of human DAF and CD59 to avoid xenograft rejection

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Science china(Life Sciences) 2008年第3期51卷 199-204页

作者： liu BingQian1, CHENG ChuanYu1, WU YuDong1, WEI JinXing1, LI GuangSan2 & MA TengXiang3 1 department of urology, the first affiliated hospital of Zhengzhou university, Zhengzhou 450052, china 2 Institute of Genetics and Development Biology, Chinese Academy of Sciences, Beijing 100101, china 3 Tianjin Institute of urology, Second hospital of Tianjin medical university, Tianjin 300211, china department of urology the First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China Institute of Genetics Development Biology Chinese Academy of Sciences Beijing 100101 China Tianjin Institute of urology Second Hospital of Tianjin Medical University Tianjin 300211 China

The expression of human α-1,2-fucosyltransferase (HT) or complement regulatory proteins has been proved as an strategy to overcome hypercute rejection in discordant xenogeneic organ transplantation. In this study, we examined whether peripheral blood mononuclear cells (PBMCs) from polytransgenic mice expressing the human HT, and complement regulatory proteins (DAF and CD59), can provide more effective protection against xenograft rejection. Transgenic mice were produced by co-injection of gene constructs for human HT, DAF and/or CD59. Flow Cytometry (FCM) was used to screen the positive transgenic mice. PBMCs from transgenic mice were incubated with 15% human serum to evaluate natural antibody binding, complement activation and expression of adhesion molecules. Three transgenes were strongly expressed in PBMCs of transgenic mice, and HT expression signifi- cantly reduced expression of the major xenoepitope galactose-α-1,3-galactose (α-Gal). Functional studies with PBMCs showed that co-expression of HT and DAF or CD59 markedly increased their re- sistance to human serum-mediated cytolysis when compared with single transgenic PBMCs. Moreover, the combined expression of triple transgenes in PBMCs led to the greatest protection against human serum-mediated cytolysis, avoided hyperacute rejection and reduced expression of adhesion mole- cules. Strong co-expression of triple transgenes was completely protected from xenograft hyperacute rejection and partially inhibited acute vascular rejection. The studies suggest that engineering mice to express triple molecules represents an critical step toward prolonging xenograft survival and might be more suitable for xenotransplantation.

关键词： α-1 2-fucosyltransferase complement regulatory proteins galactose-α-1 3-galactose hyperacute rejection acute vascular rejection

THE EFFECT OF OXYGEN APPLIEDTHROUGH DRID SHIP CONSTANT HEADVESSEL TO DLALYSATE ONDIALYSIS HYPOXEMIA

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Chinese Journal of Biomedical Engineering(English Edition) 1994年第1期3卷 35-37页

作者： Zhenguo Mi, Yusheng Bao,Chun liu, Xi Cao, Jiasheng Deng, Jin Tongdepartment of urology,first affiliated hospital of shanxi medical Collegetaiyuan, 030001, chinaHui Liang(Clinic of taiyuan Industrial and Commercial Bank,taiyuan. 030001,china) department of medical Physics Beijing medical university Beijing100083China

Thgrough experimental and clinical observation of the effect or oxygensupplyed in grid shape through constant head vessel on the PaO2 and Sao2 or bloodthrough dialyser, the result suggested that supplying oxygen throu... 详细信息

关键词： constant head vessel dialysis hypoxemia.

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Influences of dibutyryl cyclic adenosine monophosphate and forskolin on human sperm motility in vitro

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Asian Journal of Andrology 2003年第2期5卷 113-115页

作者： Ji-Hong liu, Yang LI, Zheng-Guo CAO, Zhang-Qun YEdepartment of urology, Tongji hospital, Tongji medical College, Huazhong university of Science and Technology,Wuhan 430030, china department of urology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China

Aim: To study the influences of dibutyryl cyclic adenosine monophosphate (dbcAMP) and forskolin on human sperm motility in vitro. Methods: Semen samples, aseptically obtained by masturbation and prepared by swim-up technique from 20 fertile men, were incubated with different concentrations of dbcAMP and forskolin at 37 癈. Measurements were carried out after 10 min, 20 min, 30 min and 60 min incubation. Motility parameters were estimated by using an automatic analyzing system. Results: Treatment with dbcAMP or forskolin resulted in a significant increase in sperm motility and progressive motility. The larger the concentrations of dbcAMP or forskolin, the greater the effect appeared. The straight linear velocity and curvilinear velocity were not affected by both agents. Conclusion: dbcAMP and forskolin increase the motility and progressive motility of human sperm in vitro.

关键词： dibutyryl cyclic AMP forskolin sperm motility

Voltage-dependent Anion Channels (VDAC) in Human Spermatozoa

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Voltage-dependent Anion Channels (VDAC) in Human Spermatozoa

第十五届全国泌尿外科学术会议

作者： Bianjiang liu, Zengjun Wang, Wei Zhang department of urology, first affiliated hospital of Nanjing medical university 210029

Voltage-dependent anion channels (VDAC), also known as mitochondrial porins, are a group of proteins first identified in the mitochondrial outer membrane that are able to form hydrophilic pore structures.

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Effects of the PKC inhibitor on multidrug resistance in human renal cell carcinoma cells

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Effects of the PKC inhibitor on multidrug resistance in huma...

第十三届全国泌尿外科学术会议暨第八届全球华人泌尿外科学术会议

作者： TAO liu, CHUI ZE KONG , JIANBIN BI, XIA WANG From the department of urology, the first affiliated hospital china medical university, Shenyang, china

Objectives The purpose of this study is to explore the reversal effects of PKC inhihitor on RCC cell line 786-0, which shows MDR appearance through establishes the PKC-α expression. And try to elucidate whether the i...

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Calphostin C,a protein kinase Cα inhibitor can attenuates multidrug resistance in experimental renal cell carcinomas

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Calphostin C,a protein kinase Cα inhibitor can attenuates m...

第十三届全国泌尿外科学术会议暨第八届全球华人泌尿外科学术会议

作者： TAO liu, CHUI ZE KONG, JIANBIN BI, XIA WANG, From the department of urology, the first affiliated hospital china medical university, Shenyang, china

Objectives The aim of this study was to investigate whether inhibition of PKCαisoforms could be utilized to potentiate the effects of chemotherapeutic drugs on RCC cells. Methods A renal cell carcinoma cell line, 786...

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Studies on plasma endothelin changes in varicocele patients

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Asian Journal of Andrology 1999年第3期1卷 159-160页

作者： Qing-Quan XU Ji-Chuan ZHU Hu JIANG Xiao-Feng WANG Shu-Kun HOU Qing-Li liu department of urology, People’s hospital, Beijing medical university, Beijing 100011, china department of urology People’s Hospital Beijing Medical University Beijing 100011 China

Aim: To investigate the possible role endothelin may play in the pathogenesis of varicocele and varicocele-induced infer-tility. Methods: In varicocele patients, radioimmunoassay is used to determine the blood endothelin concentration inthe spermatic vein and the antecubital vein separately. Results: The blood endothelin concentration of the spermaticvein (66.8±23.5 pg/mL) was significantly higher (P <0.05) than that of the antecubital vein (55.3±25.3 pg/mL).The endothelin concentration in the spermatic vein in Grade Ⅱ varicocele patients was not significantly different from thatin Grade Ⅲ patients ( P = 0.87). Conclusion: The higher blood endothelin level in the spermatic vein may indicate theinvolvement of endothelin in the pathophysiology of varicocele and varicocele-induced infertility. (Asian J Androl 1999Sep ; 1: 159 - 160)

关键词： endothelin varicocele infertility

Secondary PCNL in the use of complex renal stones

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Secondary PCNL in the use of complex renal stones

第十五届全国泌尿外科学术会议

作者： Zhang Kaiyan, Xing Jinchun, Chen Bin, Chen Shixin, Zhou Zhongquan, liu Rongfu, (department of urology, XiaMen first hospital, affiliated to Fujian medical university, Xiamen , china 361003)

Objective: Although the stone-free rate for PCNL in treatment of renal stone is quite high, usually more than 90%, the patients might have residual stone, especially for patients with staghorn stone. These stone fragm...

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