Calphostin C,a protein kinase Cα inhibitor can attenuates multidrug resistance in experimental renal cell carcinomas
会议名称:《第十三届全国泌尿外科学术会议暨第八届全球华人泌尿外科学术会议》
会议日期:2006年
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要:Objectives The aim of this study was to investigate whether inhibition of PKCαisoforms could be utilized to potentiate the effects of chemotherapeutic drugs on RCC cells. Methods A renal cell carcinoma cell line, 786-0, which stably express green fluorescent protein-PKC (PKC-α\786-0),