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Treatment of severely calcified coronary artery disease by intravascular lithotripsy primary outcomes and 180-day followup from the Chinese SOLSTICE Trial

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Journal of Geriatric Cardiology 2023年第1期20卷 32-39页

作者： Feng TIAN Shan-Shan ZHOU jing-Hua LIU Hui CHEN Zhi-Jun SUN Lian CHEN Qi WANG jing jing Yun-dai CHEN Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Capital Medical University Affiliated Anzhen HospitalBeijingChina Department of Cardiology Capital Medical University Affiliated Beijing Friendship HospitalBeijingChina

OBJECTIVE To assess the safety and effectiveness of intravascular lithotripsy(IVL)treatment for de novo coronary lesion involving severely calcified vessels in a Chinese *** The Clinical Trial of the ShOckwave Coronary IVL System Used to Treat CalcIfied Coronary ArtEries(SOLSTICE)was a prospective,single-arm,multicentre *** to the inclusion criteria,patients with severely calcified lesions were enrolled in the *** was used to perform calcium modification prior to stent *** primary safety endpoint was freedom from major adverse cardiac events(MACEs)at 30 *** primary effectiveness endpoint was procedural success,defined as successful stent delivery with residual stenosis<50% by core lab assessment without in-hospital *** morphological changes of calcium modification were assessed by optical coherence tomography(OCT)before and after IVL *** Patients(n=20)were enrolled at three sites in *** calcification by core lab assessment was present in all lesions,with a mean calcium angle and thickness of 300±51°and 0.99±0.12 mm(by OCT),*** 30-day MACE rate was 5%.Both primary safety and effectiveness endpoints were achieved in 95% of *** final in-stent diameter stenosis was 13.1%±5.7% with no patient had a residual stenosis<50%after *** serious angiographic complications(severe dissection grade D or worse,perforation,abrupt closure,slow flow/no-reflow)observed at any time during the *** imaging demonstrated visible multiplane calcium fracture in 80% of lesions with a mean stent expansion of 95.62%±13.33% at the site of maximum calcification and minimum stent area(MSA)of 5.34±1.64 mm^(2).CONCLUSIONS The initial coronary IVL experience for Chinese operators resulted in high procedural success and low angiographic complications consistent with prior IVL studies,reflecting the relative ease of use of IVL technology.

关键词： coronary intravascular closure

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Bisabocurcumin,a new skeleton curcuminoid from the rhizomes of Curcuma longa L.

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Chinese Chemical Letters 2011年第12期22卷 1457-1460页

作者： Yun chuan Xiao jing Xie Min Yu Miao Liu Jian Ran Zhen Xi Wei Li jing Huang West China School of Pharmacy Sichuan UniversityChengdu 610041China State Key Laboratory of Oral Diseases Sichuan UniversityChengdu 610041China

A new skeleton bisabolane-type sesquiterpene curcuminoid,bisabocurcumin（1）,along with 5 known compounds,curcumin（2）, demethoxycurcumin（3）,bidemethoxycurcumin（4）,（1E,4E）-1,5-bis（4-hydroxy-3-methoxyphenyl）-penta-1,4-dien-3-one（5）,and （1E,4E）-1-（4-hydroxy-3-methoxyphenyl）-5-（4-hydroxy phenyl-）-penta-1,4-dien-3-one（6）were isolated from the rhizomes of Curcuma longa *** structures were determined on the basis of spectroscopic ***（1） is firstly obtained from nature with a new skeleton combined by a bisabolane-type sesquiterpene and a 1,7-diphenylheptanoid through a C-C bond.

关键词： Zingiberaceae Curcuma longa Bisabolane-type sesquiterpene Curcumin Bisabocurcumin

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Effects of heterogeneity distribution on hillslope stability during rainfalls

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Water Science and Engineering 2016年第2期9卷 134-144页

作者： jing-sen Cai E-chuan Yan Tian-chyi Jim Yeh Yuan-yuan Zha Faculty of Engineering China University of Geosciences Department of Hydrology and Water Resources University of Arizona

The objective of this study was to investigate the spatial relationship between the most likely distribution of saturated hydraulic conductivity(Ks) and the observed pressure head(P) distribution within a hillslope. The cross-correlation analysis method was used to investigate the effects of the variance of ln Ks, spatial structure anisotropy of ln Ks, and vertical infiltration flux(q) on P at some selected locations within the hillslope. The cross-correlation analysis shows that, in the unsaturated region with a uniform flux boundary, the dominant correlation between P and Ksis negative and mainly occurs around the observation location of P. A relatively high P value is located in a relatively low Kszone, while a relatively low P value is located in a relatively high Kszone. Generally speaking, P is positively correlated with q/Ksat the same location in the unsaturated region. In the saturated region, the spatial distribution of Kscan significantly affect the position and shape of the phreatic surface. We therefore conclude that heterogeneity can cause some parts of the hillslope to be sensitive to external hydraulic stimuli(e.g., rainfall and reservoir level change), and other parts of the hillslope to be insensitive. This is crucial to explaining why slopes with similar geometries would show different responses to the same hydraulic stimuli, which is significant to hillslope stability analysis.

关键词： Cross-correlation analysis Heterogeneity Hillslope stability Saturated hydraulic conductivity Stochastic conceptualization Pore-water pressure

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First Enantioselective Synthesis of (2R,3R)-and(2S,3S)-2-(4-hydroxyphenyl)-3-hydroxymethyl-1,4-benzodioxan-6-carbaldehyde

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Chinese Chemical Letters 2001年第3期12卷 189-192页

作者： Wen Xin GU Xiao Bi jing Xiao chuan CHEN Xin Fu PAN Department of Chemistry National Laboratory of Applied Organic ChemistryLanzhou UniversityLanzhou 730000

A novel enantioselective synthetic approach to 1,4-benzodioxane lignans was reported in which (2R, 3R)- and (2S, 3S)-2-(4-hydroxyphenyl)-3-hydroxymethyl-1, 4-benzodioxan-6-carbaldehyde were first synthesized.

关键词： Enantioselectivity synthesis 1 4-benzodioxane lignans.

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Intragastric fish bones migrate into the liver:A case report

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World Journal of Clinical Cases 2023年第14期11卷 3256-3260页

作者： Mu-Gen dai jing-jing Zheng Jie Yang Bin Ye Department of Gastroenterology The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Gastrointestinal Surgery The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Infectious Disease The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND A foreign body in the digestive tract is a common disease in the ***,it is rare for a foreign body to migrate into the *** patients are diagnosed before or after perforation of the digestive *** removal of intrahepatic foreign bodies is an effective treatment *** SUMMARY A 55-year-old male patient was admitted to the hospital due to fever for 3 d,in addition to pain and discomfort in the right side of his *** admission,abdominal computed tomography showed a foreign body in the liver,and gastroscopy did not indicate obvious erosion or *** patient then underwent laparoscopic *** the operation,an abscess was seen near the gastric antrum and between the caudate lobes of the *** was approximately 30 mm×31 mm×23 mm in *** abscess was cut open,and a fish bone was found *** fish bone had penetrated the liver and was successfully *** was confirmed that the fish bone migrated from the stomach to the *** Although intrahepatic foreign bodies are rare,they should be diagnosed and treated as early as possible to avoid serious complications such as intrahepatic abscess,which may lead to liver resection and even life-threatening events.

关键词： Foreign body Intrahepatic Migrate Stomach Case report

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Numerical simulation of melt flow and temperature field during DC casting 2024 aluminium alloy under different casting conditions

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China Foundry 2024年第4期21卷 387-396页

作者： Jin-chuan Wang Yu-bo Zuo Qing-feng Zhu jing Li Rui Wang Xu-dong Liu Key Laboratory of Electromagnetic Processing of Materials Ministry of EducationNortheastern UniversityShenyang 110819China School of Materials Science and Engineering Northeastern UniversityShenyang 110819China Engineering Research Center of Advanced Materials Preparing Technology Ministry of EducationShenyang 110819China CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China

Casting speed,casting temperature and secondary cooling water flow rate are the main process parameters affecting the DC casting *** parameters significantly influence the flow and temperature fields during casting,which are crucial for the quality of the ingot and can determine the success or failure of the casting *** simulation,with the advantages of low cost,rapid execution,and visualized results,is an important method to study and optimize the DC casting *** the present work,a simulation model of DC casting 2024 aluminum alloy was established,and the reliability of the model was ***,the influence of casting parameters on flow field and temperature field was studied in detail by numerical simulation *** show that with the increase of casting speed,the melt flow becomes faster,the depths of slurry zone and mushy zone increase,and the variation of slurry zone depth is greater than that of mushy *** an increase in casting temperature,the melt flow rate increases,the depth of the slurry zone becomes shallower,and the depth of the mushy zone experiences only minor *** simulation results further indicate that the increase of the flow rate of the secondary cooling water slightly reduces the depths of both slurry and mushy zone.

关键词： aluminium DC casting flow field temperature field numerical simulation

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Effects of heat treatment on the microstructure and mechanical properties of Ni_(3)Al-based superalloys:A review

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International Journal of Minerals,Metallurgy and Materials 2021年第4期28卷 553-566页

作者： Yu-ting Wu Chong Li Ye-fan Li jing Wu Xing-chuan Xia Yong-chang Liu State Key Lab of Hydraulic Engineering Simulation and Safety School of Materials Science&EngineeringTianjin UniversityTianjin 300354China

Ni_(3)Al-based alloys have drawn much attention as candidates for high-temperature structural materials due to their excellent comprehensive *** microstructure and corresponding mechanical properties of Ni_(3)Al-based alloys are known to be susceptible to heat ***,a significant step is to employ various heat treatments to derive the desirable mechanical properties of the *** paper briefly summarizes the recent advances in the microstructure evolution that occurs during the heat treatment of Ni_(3)Al-based *** fromγ′phase andγphase,the precipitations ofβphase,α-Cr precipitates,and carbides are also found in Ni_(3)Al-based alloys with the addition of various alloying *** evolution in morphology,size,and volume fraction of various types of secondary phases during heat treatment are reviewed,involvingγ′phase,βphase,α-Cr precipitate,and *** kinetics of the growth of precipitates are also ***,the influences of heat treatment on the mechanical properties of Ni_(3)Al-based alloys are discussed.

关键词： intermetallics heat treatment microstructure mechanical properties

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Synthesis of macrocyclic lactones with methoxysulfonyl side chain

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Chinese Chemical Letters 2008年第4期19卷 403-405页

作者： chuan Jin Hou Xiao Mei Liang jing Ping Wu Dao Quan Wang Key Lab of Pesticide Chemistry and Application Technology Department of Applied ChemistryChina Agricultural UniversityBeijing 100094China

Two representative macrocyclic lactones with methoxysulfonyl side chain（5a and 5b）were synthesized employing Michael addition with acrolein and ring enlargement as the key steps,starting from potassium,α-oxocycloai... 详细信息

关键词： Macrocyclic lactone Ring enlargement α-Hydroxypropyl-α-methoxysulfonylcycloalkanones Synthesis

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Treatment for long-term poorly closed incisions after hepatobiliary surgery

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Hepatobiliary & Pancreatic Diseases International 2008年第3期7卷 280-283页

作者： Zhang, jing-De Wang, Shou-Jie Lv, chuan Xing, Xin Second Mil Med Univ Dept Plast Surg Changhai Hosp Shanghai 200433 Peoples R China Zhejiang Univ Sch Med Affiliated Hosp 1 Dept Plast Surg Hangzhou 310003 Zhejiang Peoples R China

BACKGROUND: Effective measures are lacking to treat long-term poorly closed incisions after hepatobiliary surgery, including chronic sinus tract and keloid. This study aimed to introduce the treatment experiences with the abdominal wall and costal margin complications after hepatobiliary surgery, and to investigate the method for prevention of this kind of complication. METHODS: We retrospectively studied 26 patients with complications of abdominal wall and costal margin after hepatobiliary surgery, who had been admitted to our hospital since 1998. The 26 patients were classified according to complications into 3 groups: chronic ulcer with costal chondritis (5 patients), single chronic ulcer (3), and keloid (18). According to the symptoms of patients, treatments given included focal removal regional flap transfer restoration and focal removal dermatoplasty combined with glucocorticoid injection, anti-scar medication, external application of silicone gel film, and pressure therapy after surgery to inhibit recurrence. RESULTS: Satisfactory results were observed in the 26 patients after the treatments. Focal and regional ache and itching disappeared, and 2-3-year follow-up revealed no recurrence. CONCLUSIONS: Attention should be paid to patients with complications of abdominal wall and costal margin after hepatobiliary surgery. Combined treatment or mainly operations produce satisfactory result.

关键词： hepatobiliary abdominal wall costal margin complications

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A robust and unique approach for tuning the energy level of Ag_(2)Se quantum dots via“on-surface”manipulation of nitrogencontaining groups of surface-coordinated ligands

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Nano Research 2023年第11期16卷 12608-12617页

作者： Meng-Yao Luo Bo Tang An-An Liu jing-Ya Zhao Zhi-Ling Zhang dai-Wen Pang The Institute for Advanced Studies and College of Chemistry and Molecular Sciences Wuhan UniversityWuhan 430072China State Key Laboratory of Medicinal Chemical Biology Tianjin Key Laboratory of Biosensing and Molecular RecognitionFrontiers Science Center for New Organic MatterResearch Center for Analytical SciencesCollege of ChemistryFrontiers Science Center for Cell ResponsesNankai UniversityTianjin 300071China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China

Effects of surface chemistry on energy levels or optical properties of semiconductor nanocrystals have attracted considerable attention and show great promise in broad ***,it remains challenging to controllably tune the photoluminescence(PL)of quantum dots(QDs)by manipulating surface ***,we investigated effects of the ligand,glutathione(GSH),on PL properties of near-infrared(NIR)Ag_(2)Se QDs by“on-surface”manipulation,that is,precisely manipulating the chelating group without dissociating the ligand from the *** anchoring of the amino group was found to be controlled by solution pH,whereas the binding of the thiol group to the Ag+was pH independent,maintaining the“on-surface”state of *** tuning the pH-controlled binding of amino groups,the energy level or the bandgap of Ag2Se QDs could be increased by up to 140 *** increased bandgap resulted in the blueshift of PL spectrum,which could be reversibly tuned by up to 75 *** pH-mediated tunable PL properties of QDs could also be extended to other nitrogen-containing pH-sensitive groups which could coordinate to the Ag+,not limited to the amino *** work would facilitate the study of nanocrystal surface chemistry and our model that the binding of amino groups affected energy levels of Ag2Se QDs might facilitate new insights into the electronic structure and energy level of other QD-ligand complexes.

关键词： quantum dot(QD) surface chemistry ligand energy level pH

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