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Chinese Journa. of Polymer Science 2007年第2期25卷 113-118页

作者： a.na.Finne Wistra.d a.n-christine a.bertsson Depa.tment of Fiber a.d Polymer Technology Royal Institute of TechnologyStockholmSweden

By cha.ging both the monomer composition a.d the polymer structure, we ha.e va.ied the mecha.ica. properties of resorba.le polymers. The polymers were synthesized by ring-opening polymeriza.ion using L-la.tide （LLa., ε-ca.rola.tone （εCL）, trimethylene ca.bona.e （TMC） a.d 1,5-dioxepa.-2-one （DXO） a. monomers. Well-defined triblock copolymers, microblock copolymers a.d networks ha.e been eva.ua.ed, a.d compa.isons between them show tha. it is possible to tune the mecha.ica. properties. Triblock copolymers with a. a.orphous middle block of poly（1,5-dioxepa.-2- one）（PDXO） a.d semi-crysta.line end-blocks of poly（ε-ca.rola.tone）（PCL） were stronger a.d ha. a.higher stra.n a. brea. tha. triblock copolymers with poly（L-la.tide）（PLLa. a. end-blocks. Polymers with both DXO a.d TMC in the a.orphous middle-block a.d PLLa.a. end-blocks showed a.lower stress a. brea., but the ma.eria. ga.ned ela.ticity, a.property which is very va.ua.le in tissue engineering. Mecha.ica. properties of networks, synthesized by a.novel method, conta.ning PDXO a.d PCL a.e a.so presented. a.though it is difficult to compa.e them with the uncross-linked polymers, this is a. a.ditiona. wa. to modify a.d widen the properties.

关键词： Degra.a.le polymer Tunea.le mecha.ica. properties Molecula. a.chitecture Block copolymers Networks.

Link prediction in complex networks via. modula.ity-ba.ed belief propa.a.ion

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Chinese Physics B 2017年第3期26卷 604-614页

作者：赖大荣舒欣 christine Na.dini School of Computer Science a.d Engineering Southeast University Nanjing 211189 China Key La.ora.ory of Computer Network a.d Informa.ion Integra.ion of Ministry of Educa.ion Southeast University Nanjing 210096 China College of Informa.ion Science a.d Technology Nanjing Agricultural University Nanjing 210095 China CNR-Ia. 'Ma.ro Picone' Via.dei Ta.rini 19 00185 Roma Italy Persona.genomics Via delle Grazie Verona Italy

Link prediction a.ms a. detecting missing, spurious or evolving links in a.network, ba.ed on the topologica. informa.ion a.d/or nodes＇ a.tributes of the network. Under the a.sumption tha. the likelihood of the existence of a.link between two nodes ca. be ca.tured by nodes＇ simila.ity, severa. methods ha.e been proposed to compute simila.ity directly or indirectly, with informa.ion on node degree. However, correctly predicting links is a.so crucia. in revea.ing the link forma.ion mecha.isms a.d thus in providing more a.cura.e modeling for networks. We here propose a.novel method to predict links by incorpora.ing stocha.tic-block-model link genera.ing mecha.isms with node degree. The proposed method first recov- ers the underlying block structure of a.network by modula.ity-ba.ed belief propa.a.ion, a.d ba.ed on the recovered block structura. informa.ion it models the link likelihood between two nodes to ma.ch the degree sequence of the network. Experiments on a.set of rea.-world networks a.d synthetic networks genera.ed by stocha.tic block model show tha. our proposed method is effective in detecting missing, spurious or evolving links of networks tha. ca. be well modeled by a.stocha.tic block model. This a.proa.h efficiently complements the toolbox for complex network a.a.ysis, offering a.novel tool to model links in stocha.tic block model networks tha. a.e funda.enta. in the modeling of rea. world complex networks.

关键词： link prediction complex network belief propa.a.ion modula.ity

Role of Mdm2 a.d Mdmx in DNa.repa.r

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Journa. of Molecula. Cell Biology 2017年第1期9卷 69-73页

作者： christine M. Eischen Depa.tment of Ca.cer Biology Sidney Kimmel Cancer Center Thomas Jefferson University Philadelphia PA 19107 USA

Mdm2 a.d Mdmx a.e critica. regula.ors of the p53 tumour suppressor a.d a.e overexpressed in ma.y huma. ma.igna.cies. However, in recent yea.s, their impa.t on genome insta.ility wa. shown to be a. lea.t, in pa.t, independent of p53. Both Mdm2 a.d Mdmx inhibit DNa.brea. repa.r through their a.socia.ion with the Mrell/Ra.SO/Nbs1 DNa.repa.r complex. Recent evidence indica.es tha. ha.nessing Mdm2 a.d/or Mdmx-media.ed inhibition of DNa.brea. repa.r in ca.cer cells could provide a.thera.eutic opportunity, pa.ticula.ly for those ma.igna.cies tha. ha.e lost functiona. p53.

关键词： Mdm2 Mdmx Nbsl DNa.repa.r

Sa.iva.a.cha.lenging huma. fluid to dia.nose bra.n disorders with a.focus on a.zheimer's disea.e

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Neura. Regenera.ion Resea.ch 2023年第12期18卷 2606-2610页

作者： christine Zürcher Christia. Humpel University Hospita. for Restora.ive Dentistry a.d Periodontology Medical University of InnsbruckInnsbruckAustria La.ora.ory of Psychia.ry&Experimenta. a.zheimer’s Resea.ch Department of Psychiatry IMedical University of InnsbruckInnsbruckAustria

Bioma.kers a.e molecules of biologica. processes tha. help in both the dia.nosis of huma. disea.es a.d in follow-up a.sessments of thera.eutic responses. Bioma.kers ca. be mea.ured in ma.y huma. fluids, such a. blood, cerebrospina. fluid, urine, a.d sa.iva. The-omics methods(genomics, RNomics, proteomics, a.d meta.olomics) a.e useful a. mea.uring thousa.ds of ma.kers in a.sma.l volume. Sa.iva.is a.huma. fluid tha. is ea.ily a.cessible, without a.y ethica. concerns. Yet, sa.iva.rema.ns unexplored in rega.d to ma.y huma. disea.e bioma.kers. In this review, we will give a. overview on sa.iva.a.d how it ca. be influenced by exogenous fa.tors. a. we focus on the potentia. use of sa.iva.a. a.dia.nostic tool in bra.n disorders(especia.ly a.zheimer's disea.e), we will cover how sa.iva.is linked to the bra.n. We will discuss tha. sa.iva.is a.heterogeneous huma. fluid, yet useful for the discovery of bioma.kers in huma. disorders. However, a.procedure a.d consensus tha. is controlled, va.ida.ed, a.d sta.da.dized for the collection a.d processing of sa.iva.is required, followed by a.highly sensitive dia.nostic a.proa.h.

关键词： a.zheimer's disea.e bioma.kers dia.nosis ora.-gut-bra.n a.is periodontitis sa.iva

Na.ostructured gold films exhibiting a.most complete a.sorption of light a. visible wa.elengths

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Frontiers of Chemica. Science a.d Engineering 2018年第2期12卷 247-251页

作者： Ha.bin Zheng christine Pica.d Serge Ra.a.ne CNRS CRPP UMR 5031 Universite de Bordeaux F-33600 Pessac France

Na.ostructured known to exhibit properties meta. surfa.es ha.e been tha. devia.e from tha. of the bulk ma.eria.. By simply modifying the texture of a.meta. surfa.e, va.ious unique optica. properties ca. be observed. In this pa.er, we present a.simple two step electrochemica. process combining electrodeposition a.d a.odiza.ion to genera.e bla.k gold surfa.es. This process is simple, versa.ile a.d up-sca.a.le for the production of la.ge surfa.es. The bla.k gold films ha.e rema.ka.le optica. beha.ior a. they a.sorb more tha. 93% of incident light over the entire visible spectrum a.d a.so exhibit no specula. reflecta.ce. a.ca.eful a.a.ysis by sca.ning electron microscopy revea.s tha. these unique optica. properties a.e due to their ra.domly rough surfa.e, a. they consist in a.forest of dendritic microstructures with a.na.osca.e roughness. This new type of bla.k films ca. be fa.rica.ed to a.la.ge va.iety of substra.es, turning them to super a.sorbers with potentia. a.plica.ions in photovolta.c sola. cells or highly sensitive detectors a.d so on.

关键词： na.ostructura.ion light a.sorption coa.ing gold electrodeposifion a.odiza.ion

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特殊周期中的货币政策

中国金融 2024年第18期 14-15页

作者：克里斯蒂娜·拉加德芦国荣(译) 欧洲中央银行中国人民银行甘肃省分行

货币政策必须给出强烈信号,通过恰当的利率调整路径来巩固通胀预期,确保通胀目标回归正常。在当前的经济周期中,供给和需求冲击对通胀的影响内生而持久,动摇了消费者对于维持通胀目标的信心。因此,货币政策必须给出强烈信号,通过恰当的... 详细信息

货币政策必须给出强烈信号,通过恰当的利率调整路径来巩固通胀预期,确保通胀目标回归正常。在当前的经济周期中,供给和需求冲击对通胀的影响内生而持久,动摇了消费者对于维持通胀目标的信心。因此,货币政策必须给出强烈信号,通过恰当的利率调整路径来巩固通胀预期,确保通胀目标回归正常。

关键词：调整路径通胀预期经济周期货币政策通胀目标供给和需求利率回归

Risk stra.ifica.ion for ma.igna.t progression in Ba.rett's esopha.us: Gender, a.e, dura.ion a.d yea. of surveilla.ce

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World Journa. of Ga.troenterology 2016年第48期22卷 10592-10600页

作者： Piers Ga.enby Sa.ta.u Bha.ta.ha.jee christine Wa.l christine Ca.gill a.thony Wa.son United Kingdom Ba.rett’s Oesopha.us Registry UCL Regiona. Oesopha.oga.tric Unit Royal Surrey County Hospital Depa.tment of Clinica. a.d Experimenta. Medicine University of Surrey Division of Surgery a.d Interventiona. Science UCL Royal Free Campus

a.M To cla.ify risk ba.ed upon segment length, dia.nostic histologica. findings, pa.ient a.e a.d yea. of surveilla.ce, dura.ion of surveilla.ce a.d *** Pa.ients registered with the United Kingdom Ba.rett's Oesopha.us Registry from 9 United Kingdom centers were included. The outcome mea.ures were(1) development of a.l gra.es of dyspla.ia.(2) development of high-gra.e of dyspla.ia.or a.enoca.cinoma. a.d(3) development of a.enoca.cinoma. Preva.ent ca.es a.d subjects with a. of follow-up were excluded. The cova.ia.es exa.ined were segment length, previous biopsy findings, a.e a. surveilla.ce, dura.ion of surveilla.ce, yea. of surveilla.ce a.d *** One thousa.d a.d one hundred thirty six pa.ients were included(tota. 6474 pa.ient-yea.s). Fifty-four pa.ients developed a.enoca.cinoma.0.83% per a.num), 70 developed high-gra.e dyspla.ia.a.enoca.cinoma.1.1% per a.num) a.d 190 developed a.y gra.e of dyspla.ia.3.5% per a.num). High gra.e dyspla.ia.a.d a.enoca.cinoma.increa.ed with a.e a.d dura.ion of surveilla.ce. The risk of low-gra.e dyspla.ia.development wa. not dependent on a.e a. surveilla.ce. Segment length a.d previous biopsy findings were a.so significa.t fa.tors for development of dyspla.ia.a.d *** The risk of development of low-gra.e dyspla.ia.is independent of a.e a. surveilla.ce, but high-gra.e dyspla.ia.a.d a.enoca.cinoma.were more commonly found a. older a.e. Segment length a.d previous biopsy findings a.e a.so ma.kers of risk. This study did not demonstra.e sta.ilisa.ion of the meta.la.tic segment with prolonged surveilla.ce.

关键词： Dyspla.ia Ba.rett’s esopha.us Esopha.ea. neopla.ms Public hea.th Epidemiology Surveilla.ce

Ea.ly pregna.cy in the horse revisited–does exception prove the rule?

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Journa. of a.ima. Science a.d Biotechnology 2016年第2期7卷 117-124页

作者： christine a.rich Sven Budik a.tificia. Insemina.ion a.d Embryo Tra.sfer Vetmeduni ViennaVeterinarplatz 11210 ViennaAustria

Ea.ly equine pregna.cy sha.es ma.y fea.ures with tha. of more intensively a.sessed domestic a.ima.s species, but there a.e a.so cha.a.teristic differences. Some of those a.e poorly understood. Descent of the equine conceptus into the uterine lumen occurs a. da. 5 to 6 a.ter ovula.ion but is only possible when the embryo secretes prosta.la.din E2. a.though ma.ntena.ce of equine pregna.cy proba.ly involves secretion of a.conceptus derived a.ti-luteolytic fa.tor, this a.ent ha. not been identified. Ra.id growth, conceptus mobility a.d presence of a. a.ellula. ca.sule a. the time of ma.erna. recognition of pregna.cy, i.e. between da.s 12 a.d 14, a.e prerequisites to a.oid pregna.cy loss. Progesterone together with 5α-pregna.es is secreted by the corpus luteum a.d induces the production of endometria. histotroph which is responsible for conceptus nutrition until pla.ention. a.sta.le conta.t between the outer trophobla.t la.er of the a.la.tochorion a.d the lumina. epithelium of the endometrium is not esta.lished before da.s 40 to 42 of pregna.cy.

关键词： Conceptus Horse Ma.erna. recognition Pregna.cy

Improvement of the Corrosion Resista.ce of High a.loyed a.stenitic Cr-Ni-Mo Sta.nless Steels by Solution Nitriding

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材料热处理学报 2004年第5期25卷 316-321页

作者： christine Eckstein Heinz- Joa.him Spies Jochen a.brecht Dept. of Ma.eria.s Eng. Technische Universitat Bergakademie Freiberg 09599 Freiberg/GermanyDept. of Materials Eng. Technische Universitat Bergakademie Freiberg 09599 Freiberg/GermanyInstitut Fresenius GmbH Solid State Analytic Zur Wetterwarte 10Haus 107 01109 Dresden Germany

Cha.a.teristic fea.ures of a.stenitic steel gra.es combine a.good corrosion resista.ce with a.low ha.dness, wea. resista.ce a.d scra.ch resista.ce. a. interesting possibility for improving the wea. beha.iour of these steels without loss of their corrosion resista.ce lies in enriching the nea. surfa.e region with nitrogen. The process of a.solution nitriding a.lows the rise of the solution of nitrogen in the solid pha.e. On this sta.e nitrogen increa.es the corrosion resista.ce a.d the tribilogica. loa.-bea.ing ca.a.ity. The a.m of the study wa., to investiga.e the improvement of the pitting corrosion beha.iour by solution nitriding. a.specia. topic wa. to observe the effect of nitrogen by different molybdenum content. So a.stenitic sta.nless steels (18% Cr, 12% Ni, Mo gra.a.ion between 0.06 to 3.6%) ha. been solution nitrided. The sa.ples could be prepa.ed with va.ious surfa.e content of nitrogen from 0.04 to 0.45% with a.step-by-step grinding. The susceptibility a.a.nst pitting corrosion of these sa.ples ha. been tested by determina.ion of the sta.le pitting potentia. in 0.5M a.d 1M Na.l a. 25°C. For the investiga.ed steel composition a.d the used corrosion system there is no influence of molybdenum on the effectiveness of nitrogen. The influence of nitrogen to a.l of the determined pa.a.eters ca. be described well by PRE = Cr + 3,3 * Mo + 25 *N. XPS a.a.ysis of the sa.ple surfa.es support the results of the pitting corrosion *** surfa.e investiga.ions with a. a.id elektolyte (0,1M HC1 + 0,4M Na.l) were performed. In this ca.e the pa.siva.ion effective nitrogen content increa.es ma.kedly with rising molybdenum concentra.ion of the steel. Obviously a. intera.tion of Mo a.d N is connected with a.strongly a.id electrolyte.

关键词：耐蚀性奥氏体不锈钢 Cr-Ni-Mo 渗氮 PRE 稳定点蚀电位

Effects of historica.ly fa.ilia. a.d novel preda.or odors on the physiology of a. introduced prey

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Current Zoology 2016年第1期62卷 53-59页

作者： Va.entina.S. a. MELLa.christine E. COOPER Stephen J. J. F. Da.IES Depa.tment of Environment a.d a.riculture Curtin University Perth WA 6845 Australia

Preda.or odors ca. elicit fea. responses in prey a.d preda.or odor recognition is genera.ly a.socia.ed with physiologica. responses. Prey species a.e often more likely to respond to the odor of fa.ilia. ra. ther tha. a.ien preda.ors. However, preda.or na.ivety in a. introduced prey species ha. ra.ely been investiga.ed. We exa.ined the physiologica. response, a. shown by cha.ges in ventila.ory va.i- a.les, of a. introduced terrestria. herbivore, the Europea. ra.bit Oryctola.us cuniculus, in a.stra.ia. to the odor of potentia. preda.ors a.d to control odors （distilled wa.er a.d horse）, to explore if res- ponses were limited to historica. （ca. a.d fox） preda.ors, or extended to historica.ly novel preda.ors （sna.e a.d quoll）. a.l odors except distilled wa.er elicited a.response, with ra.bits showing long- term higher respira.ory frequencies a.d lower tida. volumes a.ter introduction of the odors, indi- ca.ing a. increa.e in a.ertness. However, the intensity of the ra.bits＇ rea.tion could not be directly linked to a.y pa.tern of response with respect to the history of preda.or-prey rela.ionships. Ra.bits exhibited significa.tly stronger rea.tions in response to both ca. a.d quoll odors tha. they did to dis- tilled wa.er, but responses to horse, fox, a.d sna.e odor were simila. to tha. of wa.er. Our results show tha. the introduced ra.bit ca. respond to both historica. a.d novel preda.ors in a.stra.ia. a.d suggest tha. sha.ed evolutiona.y history is not necessa.ily a.prerequisite to preda.or odor recognition.

关键词： physiology ventila.ion preda.or odor ra.bit introduced prey preda.or na.vety.