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Effect of resistance training volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older females:Systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and Health Science 2024年第2期13卷 145-159页

作者： Paulo Ricardo Prado Nunes Pamela Castro-e-souza Anselmo Alves de Oliveira Bruno de Freitas Camilo gislaine Cristina-souza Lucio Marques Vieira-souza Marcelo Augusto da silva Carneiro department of Body and Human Movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University Center of Planalto de Araxa(UNIARAXA) 38180-129 AraxaMGBrazil Physical Activity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Exercise and Nutrition Research group(gPEN) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sciences and Physical Exercise Study and Research group(gEPCEEX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physical Education Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytical study aimed to explore the effects of resistance training(RT) volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older ***:A systematic search was performed for randomized controlled trials in PubMed,Scopus,Web of Science,and *** controlled trials with postmenopausal and older females that compared RT effects on body adiposity,metabolic risk,and inflammation with a control group(Cg) were *** reviewers selected the studies,extracted the data,and performed the risk of bias and certainty of the evidence(grading of Recommendations,Assessment,development,and Evaluation(gRAde)) *** body and abdominal adiposity,blood lipids,glucose,and C-reactive protein were included for meta-analysis.A random-effects model,standardized mean difference(Hedges’ g),and 95% confidence interval(95%CI) were used for ***:Twenty randomized controlled trials(overall risk of bias:some concerns;gRAde:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic risk,and inflammation when compared to ***,HVRT demonstrated higher effect sizes than LVRT for glucose(HVRT=-1.19;95%CI:-1.63 to-0.74;LVRT=-0.78;95%CI:-1.15 to-0.41) and C-reactive protein(HVRT=-1.00;95%CI:-1.32 to-0.67;LVRT=-0.34;95%CI,-0.63 to-0.04)) when compared to ***:Compared to Cg,HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

关键词： C-reactive protein Fat mass Lipid profile Menopause Strength training

Response to Commentary by Dr. Matthew J. Clarkson on

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Journal of Sport and Health Science 2024年第5期13卷 670-671页

作者： Hugo de Luca Corrêa Lysleine Alves deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araújo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinésio silva Neto Cláudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-silva Fernando Honorato souza Vitória Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira Andrade Jonato Prestes Thiago dos Santos Rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical group Home Dialysis Center and RenalClass Sao Paulo 01239-040Brazil department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa genetic Resources and Biotechnology Brasılia 70770-917Brazil g graduate Program of genomic Sciences and Biotechnology Brasılia 71966-700Brazil

dear editor:We sincerely thank Matthew *** for his insightful commentary1 on our recent publication in the Journal of Sport and Health Science.2 Clarkson's pioneering work in the development and application of blood flow restriction (BFR) exercise protocols has undeniably laid the groundwork for subsequent investigations in this field,including our own.(3-6)His commentary not only highlights the relevance and timeliness of our study but also offers valuable perspectives on refining safety considerations for intradialytic BFR exercise among hemodialysis patients.

关键词： patients application flow

New patterns of the tree beta diversity and its determinants in the largest savanna and wetland biomes of South America

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Plant Diversity 2023年第4期45卷 369-384页

作者： Karla J.P.silva-souza Maíra g.Pivato Vinícius C.silva Ricardo F.Haidar Alexandre F.souza departamento de Ecologia Universidade Federal do Rio Grande do NorteRNBrazil Curso de Engenharia Ambiental Universidade Federal do TocantinsTOBrazil

Clear and data-driven bioregionalizations can provide a framework to test hypotheses and base biodiversity *** we used occurrence and abundance data in combination with objective analytical methods to propose two bioregionalization schemes for tree species of the Cerrado and the Pantanal in South *** also evaluated the contribution of three sets of determinants of the occurrence-and abundance-based *** compiled data on tree species composition from 894 local assemblages based on species occurrences,and from 658 local assemblages based on species *** used an unconstrained community-level modelling approach and clustering techniques to identify and map tree subregions for the occurrence and the abundance data sets,*** clustering analyses were conducted to investigate floristic affinities between the subregions and to map broader floristic *** used multinomial logistic regression models,deviance partitioning,and rank-sum tests to assess the main subregion *** identified 18 occurrence-and four abundance-based subregions in the *** hierarchical classifications grouped the occurrence-based subregions into nine floristic zones and abundance-based subregions into two broad floristic *** in subregions were explained mainly by environmental factors and spatial structure in both occurrence and abundance data *** occurrence-and abundance-based subregions are complementary approaches to disentangle macroecological patterns and to plan conservation efforts in the Cerrado and the *** findings based on occurrence data revealed more complex and interdigitated boundaries between subregions of tree species than previously *** environment,historical stability,and human effects act in a synergetic way on the distribution of the ***,the relevance of contemporary environmental factors to the subregion patterns we found alert us to the profound im

关键词： Cerrado Pantanal Savanna Biogeographical regionalization Biodiversity hotspot South America

Modeling unmanned aerial vehicle system for identifying foci of arboviral disease with monitoring system

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International Journal of Modeling, Simulation, and Scientific Computing 2022年第3期13卷 98-120页

作者： John David S.Belem Hidalyn Theodory C.M.souza Alvaro Sobrinho Lenardo Chaves E.silva Helder Fernando de Araujo Oliveira Federal Rural University of the Semiarid BR-233s/n Cara´ubasRio Grande do Norte 59780-000Brazil Federal Rural University of the Semiarid BR-226s/n Pau dos FerrosRio Grande do Norte 59900-000Brazil Federal University of the Agreste of Pernambuco Avenida Bom Pastor s/nGaranhuns Pernambuco 55292-270Brazil

People who live in low-income and hard-to-reach regions are usually the most affected ones by high incidences of arboviral diseases,increasing morbidity and mortality rates,and public health *** present the modeling of hardware and software components of an unmanned aerial vehicle(UAV)system by mathematical tools,focusing on monitoring foci of arboviral diseases transmitted by Aedes aegypti mosquito,e.g.,Zika,Chikungunya,and *** used restriction equations and the colored Petri nets formal modeling language to represent the flight dynamics and the software components of the system,*** evaluated the specification of desired behaviors of the monitoring system using simulations and the model checking *** results showed the completeness and correctness of the *** design of such a system is challenging due to the potential risks to people and the ***,this study provides insights into the development of an UAV system for such an application *** monitoring system has the potential of improving the efficiency in identifying foci of arboviral diseases.

关键词： System modeling unmanned aerial vehicle colored Petri nets flight dynamics arboviral diseases

Characterization of goat whey proteins and their bioactivity and toxicity assay

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Food Bioscience 2022年第2期46卷 833-843页

作者： Maria Isabel Ferreira Campos Paula Perazzo de souza Barbosa Laura Junqueira Camargo Luciano Da silva Pinto Bianca Mataribu Catarina Serr˜ao Luis Fernando Marques-Santos Jos´e Hon´orio Lopes Julia Mariano Caju de Oliveira Carlos Alberto de Almeida gadelha Tatiane Santi-gadelha Programa de P´os-graduaç˜ao em Ciˆencia e Tecnologia de Alimentos Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil departamento de Biologia Molecular Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil Centro de desenvolvimento Tecnol´ogico Universidade Federal de PelotasRio Grande do SulBrazil Programa de P´os-graduaç˜ao em Ciˆencias da Nutriç˜ao Universidade Federal da ParaíbaJo˜ao PessoaParaíbaBrazil

goat whey is an industry-discarded dairy by-product that has interesting nutritional value and a nutrient composition with important functional potential,where proteins have a high biological value and play an important role in the organism’s ***,the aim of this study was to identify,quantify,concentrate and investigate the capacity of goat whey proteins to perform different biological activities and to evaluate their acute *** proteins were quantified and identified by Bradford,Kjehdal and SDS-PAgE *** activity was performed against Listeria monocytogenes,Salmonella spp.,Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli microorganisms and showed MIC ranging from 15 to 120μg mL-1,with the highest inhibition for *** *** activity was performed against human malignant melanoma cells and their proliferation inhibition was up to 66.8%within 72 h of *** highest antioxidant capacity was obtained at concentration 2 mg that showed 29.69%of inhibition of DPPH radical *** acute toxicity test was performed using Artemia franciscana larvae in which whey proteins were able to preserve larval survival throughout ***,we can conclude that goat’s whey has proteins that can play a positive effect on health,with antimicrobial activity and without *** present study highlights the great potential of goat’s whey to be developed as a safe biopreservative or as a functional ingredient in the food industry.

关键词： goat whey proteins Malignant cells Antimicrobial Antioxidant capacity Whey protein functionality

Recycling process and proto-kimberlite melt metasomatism in the lithosphere-asthenosphere boundary beneath the Amazonian Craton recorded by garnet xenocrysts and mantle xenoliths from the Carolina kimberlite

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geoscience Frontiers 2022年第5期13卷 89-105页

作者： Fernanda gervasoni Tiago Jalowitzki Marcelo Peres Rocha Ricardo Kalikowski Weska Eduardo Novais-Rodrigues Rodrigo Antonio de Freitas Rodrigues Yannick Bussweiler Elisa Soares Rocha Barbosa Jasper Berndt Elton Luiz Dantas Valmir da silva souza Stephan Klemme Centro de Engenharias Universidade Federal de Pelotas(UFPel)PelotasBrazil Programa de Pós-graduação em geociências Universidade Federal do Rio Grande do SulPorto AlegreBrazil Programa de Pós-graduação em geologia Instituto de GeociênciasUniversidade de Brasília(UnB)BrasíliaBrazil Faculdade de geociências Universidade Federal do Mato Grosso(UFMT)CuiabáBrazil Institut für geologie und Mineralogie Universität zu KölnGermany Faculdade de Ciências e Tecnologia Universidade Federal de Goiás(UFG)Aparecida de GoiâniaBrazil Institut für Mineralogie Universität MünsterMünsterGermany

Here we present new data on the major and trace element compositions of silicate and oxide minerals from mantle xenoliths brought to the surface by the Carolina kimberlite,Pimenta Bueno Kimberlitic Field,which is located on the southwestern border of the Amazonian *** also present Sr-Nd isotopic data of garnet xenocrysts and whole-rocks from the Carolina *** xenoliths are mainly clinopyroxenites and *** of the clinopyroxenites were classified as gPP–PP–PKP(garnet-phlogopite peridotite,phlogopite-peridotite,phlogopite-K-richterite peridotite)suites,and two clinopyroxenites(eclogites)and two garnetites are relicts of an ancient subducted *** and pressure estimates yield 855–1102℃ and 3.6–7.0 gPa,*** are enriched in light rare earth elements(LREE)(La_(N)/Yb_(N)=5–62;Ce_(N)/Sm_(N)=1–3;where N=primitive mantle normalized values),they have high Ca/Al ratios(10–410),low to medium Ti/Eu ratios(742–2840),and low Zr/Hf ratios(13–26),which suggest they were formed by metasomatic reactions with CO_(2)-rich silicate *** with high TiO_(2)(>2.0 wt.%),Al_(2)O_(3)(>12.0 wt.%),and FeOt(5.0–13.0 wt.%)resemble those found in the groundmass of kimberlites,lamproites and ***,phlogopite with low TiO_(2)(gPP-PP-PKP,and in MARID(mica-amphibole-rutile-ilmenite-diopside)and PIC(phlogopite-ilmenite-clinopyorxene)*** gPP-PP-PKP suite of xenoliths,together with the clinopyroxene and phlogopite major and trace element signatures suggests that an intense proto-kimberlite melt metasomatism occurred in the deep cratonic lithosphere beneath the Amazonian *** Sr-Nd isotopic ratios of pyrope xenocrysts(g3,g9 and g11)from the Carolina kimberlite are characterized by high ^(143)Nd/^(144)Nd(0.51287–0.51371)and eNd(+4.55 to+20.85)accompanied with enriched ^(87)Sr/^(86)Sr(0.70405–0.71098).These results suggest intera

关键词： Carolina kimberlite K-rich mantle xenoliths Ancient subducted slab Proto-kimberlite melt metasomatism

Unraveling one billion years of geological evolution of the southeastern Amazonia Craton from detrital zircon analyses

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geoscience Frontiers 2022年第5期13卷 129-152页

作者： Camille Rossignol Paul Yves Jean Antonio Francesco Narduzzi Eric Siciliano Rego Lívia Teixeira Romário Almeida de souza Janaína N.Ávila Marco A.L.silva Cristiano Lana Ricardo I.F.Trindade Pascal Philippot departamento de geofísica Instituto de AstronomiaGeofísica e Ciências Atmosféricas da Universidade de São PauloRua do Matão1226-Cidade UniversitáriaSão Paulo 05508-090Brazil Institut de Physique du globe de Paris Universitéde ParisCNRSParisFrance géosciences Montpellier Universitéde MontpellierCNRSUniversitédes AntillesMontpellierFrance Instituto de geociências Universidade de São PauloRua do Lago562-Cidade UniversitáriaSão Paulo 05508-080Brazil Instituto de geociências e Engenharias Universidade Federal do Sul e Sudeste do Pará–UNIFESSPAFolha 17Quadra 04Lote especialNova MarabáMarabáPará68505-080Brazil Research School of Earth Sciences The Australian National University142 Mills RoadCanberraACT 2601Australia Applied Isotope Research group Departamento de GeologiaEscola de MinasUniversidade Federal de Ouro PretoRua Diogo de Vasconcelos12235400-000 Ouro PretoMGBrazil

despite representing one of the largest cratons on Earth,the early geological evolution of the Amazonia Craton remains poorly known due to relatively poor exposure and because younger metamorphic and tectonic events have obscured initial *** this study,we investigated the sedimentary archives of the Carajás Basin to unravel the early geological evolution of the southeastern Amazonia *** Carajás Basin contains sedimentary rocks that were deposited throughout a long period spanning more than one billion years from the Mesoarchean to the *** oldest archives preserved in this basin consist of a few ca.3.6 ga detrital zircon grains showing that the geological roots of the Amazonia Craton were already formed by the *** the Paleoarchean or the early Mesoarchean(ga),the Carajás Basin was large and rigid enough to sustain the formation and preservation of the Rio Novo group greenstone ***,during the Neoarchean,at ca.2.7 ga,the southeastern Amazonia Craton witnessed the emplacement of the Parauapebas Large Igneous Province(LIP)that probably covered a large part of the craton and was associated with the deposition of some of the world largest iron *** emplacement of this LIP immediately preceded a period of continental extension that formed a rift infilled first by iron formations followed by terrigenous *** major change of sedimentary regime might have been controlled by the regional tectonic evolution of the Amazonia Craton and its emergence above *** the Paleoproterozoic,at ca.2.1 ga,the Rio Fresco group,consisting of terrigenous sediments from the interior of the Amazonia Craton,was deposited in the Carajás *** that time,the Amazonian lithosphere could have either underwent thermal subsidence forming a large intracratonic basin or could have been deformed by long wavelength flexures that induced the formation of basins and swells throughout the craton under the influence of

关键词： Carajás Basin Chemical Abrasion–LA-ICP-MS analyses Age distribution comparison Parauapebas Large Igneous Province Transamazonian orogeny

Ferric carboxymaltose for anemia in Crohn’s disease patients at a tertiary center:A retrospective observational cohort study

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World Journal of Clinical Cases 2023年第12期11卷 2740-2752页

作者： Natália souza Nunes Siqueira Livia Bitencourt Pascoal Bruno Lima Rodrigues Marina Moreira de Castro Alan Sidnei Corrêa Martins Dante Orsetti silva Araújo Luis Eduardo Miani gomes Michel gardere Camargo Maria de Lourdes Setsuko Ayrizono Raquel Franco Leal Inflammatory Bowel Disease Research Laboratory GastrocenterColorectal Surgery UnitSchool of Medical SciencesUniversity of Campinas(Unicamp)Campinas 13083-878São PauloBrazil

BACKgROUND Although the gastrointestinal tract is the most affected by Crohn’s disease(CD),the condition triggers other consequent manifestations,and iron deficiency anemia(IDA)is one of the most ***(IV)iron replacement is currently available through several drugs,such as ferric hydroxide sucrose and ferric carboxymaltose(FCM).However,the clinical management of these conditions can be *** To elucidate the drug’s effectiveness,the present study analyzed,through medical records,the clinical and epidemiological data of a cohort of patients with active CD who received IV FCM for the IDA *** This retrospective observational study included 25 patients with active CD,severe anemia,and refractory to previous conventional *** were evaluated two times:During the last treatment with ferric hydroxide sucrose and treatment with *** After treatment with FCM,parameters of IDA assessment significantly improved,serum hemoglobin(Hb)levels increased in 93%of patients(Pg/dL in a single *** addition,86%of the patients showed an increase in serum iron(Pgative association with the ileal and colonic CD and use of biologics and a positive association with patients who developed CD later in life after the age of 40(A3)and with a stenosing(B2)and fistulizing(B3)*** values of Hb and hematocrit after ferric hydroxide sucrose treatment remained similar to those found before *** This study demonstrated that FCM is an important therapeutic strategy for treating IDA in CD patients,achieving satisfactory results in refractory cases.

关键词： Ferric carboxymaltose Iron deficiency anemia Crohn’s disease Inflammatory bowel disease Anemia Clinical management

Maternal hyperthyroidism increases the synthesis activity and the osteogenic markers expression of calvarial osteoblasts from offspring in a murine model

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BIOCELL 2023年第2期47卷 423-430页

作者： FABIANA ROCHA ARAÚJO BRUNO MACHADO BERTASSOLI ISABELLA CRISTINA souza FÉLIX DOUgLAS MARINHO ABREU NATÁLIA MELO OCARINO AMANDA MARIA SENA REIS JUNEO FREITAS silva ROgÉRIA SERAKIdeS Núcleo de Células Tronco e Terapia Celular Animal(NCT-TCA) Veterinay SchoolUniversidade Federal de Minas GeraisBelo HorizonteMinas Gerais31270-901Brasil Universidade de Uberaba(UNIUBE) UberabaMinas Gerais38065-300Brasil Instituto de Ciências Biológicas Universidade Federal de Minas GeraisBelo HorizonteMinas Gerais31270-901Brasil Universidade Estadual de Santa Cruz Campus Soane Nazare de AndradeIlheusBahiaBrasil

To evaluate the characteristics and synthesis activity of osteoblasts extracted from the calvaria of offspring of rats exposed to maternal *** adult Wistar rats were divided into two groups,one control and one treated with daily administration of L-thyroxine by an orogastric tube(50μg/animal/day)during *** days after delivery and confirmation of the mothers’hyperthyroidism,the offspring were euthanized for the extraction of osteoblasts from the *** 7,14,and 21 days,proliferation activity was assessed using MTT assay,while alkaline phosphatase(ALP)activity was assessed by the BCIP/NBT *** 21 days,the total area of the mineralized matrix stained by von Kossa was evaluated by *** expression of gene transcripts for Runx2,Bmp2,Fgfr1,collagen type 1(Col1),osteocalcin(Oc),and osteopontin(Op)were evaluated by real-time *** were compared using the Student’s *** activity was significantly higher at 14 and 21 days in cultures of osteoblasts extracted from offspring exposed to maternal hyperthyroidism,while MTT conversion was significantly lower at 21 days in this *** cultures of neonates exposed to maternal hyperthyroidism also showed a larger total area of mineralized matrix and greater expression of gene transcripts for Oc and *** hyperthyroidism increases the activity of matrix synthesis,alkaline phosphatase activity,and expression of gene transcripts for osteocalcin and osteopontin in the osteoblasts,extracted from the calvaria of the offspring,which may be one of the mechanisms of premature fusion of cranial sutures.

关键词： Craniosynostosis Intramembranous growth Ossification Rat Thyroid dysfunction