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InfoMat 2021年第11期3卷 1295-1310页

作者： Myeong-Chang Sung Gwang-hee Lee Dong-Wan kim School of Civil Environmental and Architectural EngineeringKorea UniversitySeoulSouth Korea

Efficient electrocatalysis at the cathode is essential for overcoming the limitations of Li-O_(2) batteries such as poor stability and low rate ***,we systematically studied the kinetic behavior of a Li-O_(2) battery comprising perovskite La_(0.8)Sr_(0.2)VO_(3) nanofibers formed by partial Sr-cation doping and V cations with multiple oxidation *** with undoped LaVO_(3) and La_(0.8)Sr_(0.2)VO_(4) nanofibers,perovskite La_(0.8)Sr_(0.2)VO_(3) nanofibers exhibited an improved capacity of 2000 mA g^(-1),and a 20-times-longer cycle life in Li-O_(2) batteries.X-ray photoelectron spectroscopy,electron paramagnetic resonance spectroscopy,and photoluminescence analyses revealed that the performance variations mainly originated from crystal defects,which modulate oxygen reduction/evolution *** in situ Raman analysis,we showed that these structural defects are closely related to the oxygen reduction/evolution behavior of La_(0.8)Sr_(0.2)VO_(3) nanofibers and result in fewer parasitic *** study offers insights into the potential rate capability of Li-O_(2) batteries and related devices.

关键词： electrocatalysts La_(0.8)Sr_(0.2)VO_(3) Li-O_(2)battery nanofiber perovskite structure

Evaluation of the safety of hair essence containing 0.05% purified bee venom on the skin and eyes of rabbits

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Journal of Traditional Chinese Medicine 2020年第1期40卷 67-72页

作者： Mi Kyung Lim Eun Hye Han Sang Ho Lee Jee hee kim R&D Center KoreaeundanGyeonggi-do 13207Republic of Korea

OBJECTIVE:To investigate the safety of hair essence containing 0.05%purified bee venom(HE-PBV)on the skin and eyes of New Zealand White ***:HE-PBV which contained 0.05%PBV,purified water,and glycerin,was used as the test *** skin-irritation test(SIT)and eye-irritation test(EIT)were conducted according to the Draize *** the SIT,HE-PBV(0.5 m L)dropped gauze was attached both intact and abraded skin for 24 *** other side of the skin was used as *** 24 and 72 h,the treatment site was observed and scored according to evaluation criteria for skin *** the EIT,the rabbits were divided into two groups:eye-washed(three rabbits)and non-eye-washed(six rabbits).HE-PBV(0.1 m L)was squirted into the right eye of *** left eye was untreated and used as a ***,20-30-s later,the eyes of rabbits in the eye-washed group were washed with^50 m L of physiologic(0.9%)salt ***,1,2,3,4 and 7 d after the start of the EIT,the eyes and behavior of the rabbits were *** degree of eye irritation elicited by HE-PBV was determined in three steps and then the criteria of the classification of eye-irritation ***:The SIT revealed erythema and edema at the site of HE-PBV *** 72 h,the body weight of rabbits was reduced slightly,but other symptoms(except erythema and edema)were not *** Primary Irritation Index score was0.6,and HE-PBV was deemed to be a slight *** EIT did not show mortality or body-weight fluctuation,but hyperemic conjunctiva and eyelid closure were noted after HE-PBV *** for these results,the score for the ophthalmic response on days 1,2,3,4 and 7 was 0,and HE-PBV was deemed to be a ***:These data suggest that HE-PBV did not elicit eye irritation,but was a slight irritant to the skin of rabbits;the latter slight would have been due to the excipients used in manufacture of the hair essence because PBV has been shown to be safe.

关键词： Alopecia Bee Venoms Hair essence Skin irritancy tests Eye irritancy tests Complementary therapies

Recurrent abducens nerve palsy with optic perineuritis

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International Journal of Ophthalmology(English edition) 2012年第2期5卷 249-250页

作者： Joo Yeon kim Seung-hee Baek Ungsoo Samuel kim Department of Ophthalmology Kim's Eye Hospital Konyang University College of Medicine Seoul Korea

Dear Sir, I am Joo Yeon kim, from the department of Ophthalmology of kim’s Eye Hospital in Seoul, Korea. I write to present a case report of recurrent abducens nerve palsy with optic perineuritis Abducens nerve palsy is associated with trauma, viral infection or inoculation, central nervous system tumors, elevated intracranial pressure and idiopathic cause [1]. Optic perineuritis is an uncommon noninfectious inflammation of the optic nerve sheath and perineural fat. Optic perineuritis

关键词： Recurrent abducens nerve palsy with optic perineuritis Figure

Assessment of pathogens and risk factors associated with bloodstream infection in the year after pediatric liver transplantation

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World Journal of Gastroenterology 2022年第11期28卷 1159-1171页

作者： Yeong Eun kim Ho Jung Choi Hye-Jin Lee Hyun Ju Oh Mi Kyoung Ahn Seak hee Oh Jung-Man Namgoong Dae Yeon kim Won Kyoung Jhang Seong Jong Park Dong-Hwan Jung Deok Bog Moon Gi-Won Song Gil-Chun Park Tae-Yong Ha Chul-Soo Ahn Ki-Hun kim Shin Hwang Sung Gyu Lee Kyung Mo kim Department of Pediatrics Asan Medical Center Children's HospitalUniversity of Ulsan College of MedicineSeoul 05505South Korea Division of Pediatric Surgery Department of SurgeryAsan Medical Center Children's HospitalUniversity of Ulsan College of MedicineSeoul 05505South Korea Division of Hepatobiliary Surgery and Liver Transplantation Department of SurgeryAsan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea

BACKGROUND Bloodstream infection(BSI)is one of the most significantly adverse events that can occur after liver transplantation(LT)in *** To analyze the profile of BSI according to the postoperative periods and assess the risk factors after pediatric *** Clinical data,collected from medical charts of children(n=378)who underwent primary LT,were retrospectively *** primary outcome considered was BSI in the first year after *** and multivariate analyses were performed to identify risk factors for BSI and respective odds ratios(ORs).RESULTS Of the examined patients,106(28%)experienced 162 episodes of pathogen-confirmed BSI during the first year after *** were 1.53±0.95 episodes per children(mean±SD)among BSIcomplicated patients with a median onset of 0.4 mo *** most common pathogenic organisms identified were Coagulase-negative staphylococci,followed by Enterococcus *** Streptococcus *** half(53%)of the BSIs were of unknown *** analysis demonstrated that young age(≤1.3 year;OR=2.1,P=0.011),growth failure(OR=2.1,P=0.045),liver support system(OR=4.2,P=0.008),and hospital stay of>44 d(OR=2.3,P=0.002)were independently associated with BSI in the year after *** BSI was frequently observed in patients after pediatric LT,affecting survival *** profile of BSI may inform clinical treatment and management in high-risk children after LT.

关键词： Bloodstream infection Liver transplantation Children Pathogens

Turbulent vortex trains in narrow square arrayed rod bundles of a dual-cooled nuclear reactor

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Science China(Technological Sciences) 2013年第9期56卷 2143-2149页

作者： kim Taehwan kim Kyung Min BAE Ji-Yeul SHIN Chang Hwan IN Wang-Kee CHO Hyung hee School of Mechanical Engineering Yonsei University Korea Atomic Energy Research Institute

The dual-cooled nuclear reactor is currently considered for improving the designs of current/future nuclear reactors. Investigation of the thermal-hydraulic characteristics of the nuclear reactor via experiments is essential for commercializing the dual-cooled nuclear reactor. In this paper, the turbulent flow in square arrayed six-rod bundles in the form of magnified copies of the dual-cooled and current OPR-1000 nuclear reactor is experimentally investigated by means of hot-wire anemometry and smoke-wire generation methods. Vortex trains which do not exist in an ordinary reactor subchannel are presented in the subchannel of the dual-cooled reactor. The vortices are induced by a span-wise velocity gradient. This flow pulsation phenomenon increases the inter-channel mixing of the subchannel. To understand the periodic feature of the pulsation, axial/cross velocities are measured and the periodic characteristic frequencies are obtained by a Fast Fourier Transform (FFT) analysis. The peak frequency that represents the quasi-periodic pulsation of the flow is increased with an increase in the axial velocity while the wavelength of the pulsation remains constant within a tested range of the Reynolds number (9000 51000). The vortex trains are highly synchronized with each other, as confirmed by means of visualization.

关键词：核反应堆旋涡列车棒束快速傅立叶变换脉动现象冷却阵列

Etching characteristics and surface modification of InGaSnO thin films under Cl_(2)/Ar plasma

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Plasma Science and Technology 2023年第10期25卷 91-96页

作者： Young-hee JOO Jae-Won CHOI Bo HOU Hyuck-In KWON Doo-Seung UM Chang-Il kim Department of Electronic and Electrical Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Firearms and Optics Daeduk UniversityDaejeon 34111Republic of Korea School of Physics and Astronomy Cardiff UniversityCardiff CF243AAUnited Kingdom Department of Electrical Engineering Sejong UniversitySeoul 05006Republic of Korea

Indium gallium tin oxide(IGTO)thin films have the potential for high mobility and lowtemperature processing,which makes them suitable for applications such as display backplanes and high-voltage switching ***,very few studies have investigated the plasmaetching characteristics of IGTO and changes in its properties after *** this study,the etching characteristics of IGTO were investigated using Cl_(2)/Ar plasma,and changes in surface properties were *** showed that the etch rate increased with an increase in the proportion of Cl_(2),with the highest etch rate observed at 69 nm min^(-1)in pure Cl_(2)plasma with a gas flow rate of 100 ***,increased radio-frequency power caused a rise in the etch rate,while a process pressure of 15 m Torr was *** primary etching mechanism for IGTO thin films under Cl_(2)plasma was a chemical reaction,and an increased work function indicated the occurrence of defects on the *** addition,the etching process reduced the surface roughness of Cl_(2)-containing plasma,whereas the etching process in pure Ar plasma increased surface *** study contributes to a better understanding of the plasmaetching characteristics of IGTO and changes in its properties after etching,providing valuable insights for IGTO-based applications.

关键词： InGaSnO Cl2-based plasma etching mechanism surface modification plasma etching

A Mathematical Model for the Deficiency-Excess Mechanism of Yin-Yang in Five Viscera

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Chinese Journal of Integrative Medicine 2014年第2期20卷 155-160页

作者： Jinhyun kim Miyoung Song Jungim Kang Sang-Kyun kim Changseok kim Hyunchul Jang Sang-hee Lee Informatics Development & Management Group Korea Institute of Oriental Medicine Division of Fusion and Convergence of MathematicalSciences National Institute for Mathematical Sciences

To raise traditional medicine to a higher level of scientific research, a mathematical model has been proposed using symbolic notations and operators to describe several disease symptoms generally recognized in traditional medicine. Even though this model to a certain degree offers a mathematical approach to identify the relationships between yin-yang and the five viscera, it is not an efficient means of explaining the pathology in traditional medicine due to its use of superfluous notations and definitions. In this paper, we introduce two concise operators, a self-development operator and an action operator： the former describes the effect of a viscus in the unbalanced state on other viscera： the latter explains the engendering and restraining relationships between the two viscera. These tools are useful to elucidate the interactions among the states of the five viscera based on yin-yang and the five elements theory. Our mathematical model with these two operators facilitates description for the scheme of deficiency-excess of yin-yang in the five viscera. Accordingly, we have mathematically refined the existing results and shown clinical applications as well.

关键词： deficiency-excess mechanism yin-yang theory engendering and the restraining operators

Brain-derived neurotrophic factor mediates macrophage migration inhibitory factor to protect neurons against oxygen-glucose deprivation

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Neural Regeneration Research 2020年第8期15卷 1483-1489页

作者： Su Hwan Bae Mi Ran Yoo Ye Yeong kim In Kyung Hong Mi hee kim Seung Hak Lee Dae Yul kim Department of Rehabilitation Medicine Asan Medical CenterUniversity of Ulsan College of MedicineSeoulRepublic of Korea Asan Institute for Life Sciences Asan Medical CenterUniversity of Ulsan College of MedicineSeoulRepublic of Korea

Macrophage migration inhibitory factor(MIF)is a chemokine that plays an essential role in immune system *** studies suggested that MIF protects neurons in ischemic ***,few studies are reported on the role of MIF in neurological recovery after ischemic *** purpose of this study is to identify the molecular mechanism of neuroprotection mediated by *** neuroblastoma cells were incubated in Dulbecco’s modified Eagle’s medium under oxygen-glucose deprivation(OGD)for 4 hours and then returned to normal aerobic environment for reperfusion(OGD/R).30 ng/mL MIF recombinant(30 ng/mL)or ISO-1(MIF antagonist;50μM)was administered to human neuroblastoma *** cell cultures were assigned to one of four groups:control,OGD/R,OGD/R with MIF,OGD/R with *** viability was analyzed using WST-1 *** levels of brain-derived neurotrophic factor(BDNF),microtubule-associated protein 2(MAP2),Caspase-3,Bcl2,and Bax were detected by western blot assay and immunocytochemistry in each group to measure apoptotic ***-1 assay results revealed that compared to the OGD/R group,cell survival rate was significantly higher in the OGD/R with MIF group and lower in the OGD/R with ISO-1 *** blot assay and immunocytochemistry results revealed that expression levels of BDNF,Bcl2,and MAP2 were significantly higher,and expression levels of Caspase-3 and Bax were significantly lower in the MIF group than in the OGD/R *** levels of BDNF,Bcl2,and MAP2 were significantly lower,and expression levels of Caspase-3 and Bax were significantly higher in the ISO-1 group than in the OGD/R *** administration promoted neuronal cell survival and induced high expression levels of BDNF,MAP2,and Bcl2(anti-apoptosis)and low expression levels of Caspase-3 and Bax(pro-apoptosis)in an OGD/R *** results suggest that MIF administration is effective for inducing expression of BDNF and leads to neuroprotection of neuronal cells

关键词： apoptosis brain-derived neurotrophic factor hypoxia in vitro ischemic stroke macrophage migration inhibitory factor nerve regeneration neuroprotective effect reperfusion

Highly efficient gene silencing and bioimaging based on fluorescent carbon dots in vitro and in vivo

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Nano Research 2017年第2期10卷 503-519页

作者： Seongchan kim Yuri Choi Ginam Park Cheolhee Won Young-Joon Park Younghoon Lee Byeong-Su kim DaI-hee Min Center for RNA Research Institute for Basic Sciences (IBS) Department of Chemistry Seoul National University Seou108826 Republic of Korea Department of Energy Engineering and Department of Chemistry Ulsan National Institute of Science and Technology (UNIST) Ulsan 44919 Republic of Korea Institute of Nanobio Convergence Technology Lemonex Inc. Seou108826 Republic of Korea College of Pharmacy Ajou University Worldcuplo 206 Yeongtong-gu Suwon 16499 Republic of Korea Department of Chemistry Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of Korea

Small interfering RNA （siRNA） is an attractive therapeutic candidate for sequence- specific gene silencing to treat incurable diseases using small molecule drugs. However, its efficient intracellular delivery has remained a challenge. Here, we have developed a highly biocompatible fluorescent carbon dot （CD）, and demonstrate a functional siRNA delivery system that induces efficient gene knockdown in vitro and in vivo. We found that CD nanoparticles （NPs） enhance the cellular uptake of siRNA, via endocytosis in tumor cells, with low cytotoxicity and unexpected immune responses. Real-time study of fluorescence imaging in live cells shows that CD NPs favorably localize in cytoplasm and successfully release siRNA within 12 h. Moreover, we demonstrate that CD NP-mediated siRNA delivery significantly silences green fluorescence protein （GFP） expression and inhibits tumor growth in a breast cancer cell xenograft mouse model of tumor-specific therapy. We have developed a multifunctional siRNA delivery vehicle enabling simultaneous bioimaging and efficient downregulation of gene expression, that shows excellent potential for gene therapy.

关键词： bioimaging carbon dot gene delivery RNA interference targeted cancer therapy

Temporal manipulation of spatiotemporal optical vortices with an Airy pulse[Invited]

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Chinese Optics Letters 2023年第12期21卷 1-5页

作者： Yimin Zang Fanli Wei hee Sung kim Andy Chong Department of Electro-Optics and Photonics University of DaytonDaytonOhio 45469USA Department of Physics Pusan National UniversityBusan 46241Republic of Korea

We demonstrate the temporal manipulation of spatiotemporal optical vortices(STOVs)by utilizing Airy *** combining a STOV with an Airy temporal profile,the STOV exhibits nondispersive,self-accelerating,and self-healing... 详细信息

关键词： spatiotemporal vortex Airy pulse manipulation