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Changes in pneumatization of the maxillary air sinuses in Korean adults following biomimetic oral appliance therapy

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2021年第9期7卷 133-138页

作者： G.Dave Singh hee Nam kim Institute of Craniofacial Sleep Medicine Vivos TherapeuticsInc.9135 S Ridseline Blvd Suite ft100Highlands RanchCO 80129United States Star White Dental Clinic South Korea

Objective:For the treatment of obstructive sleep apnea in adults,mandibular advancement devices(MADs)are often *** adults with a prognathic mandibular phenotype are at risk of developing an unfavorable facial profile,midfacial development using biomimetic oral appliance therapy might provide a suitable ***,the effect of this procedure on the maxillary air sinuses is unknown;therefore,changes in sinus pneumati-zation were investigated in this ***:After obtaining informed consent,16 consecutive Korean adults with midfacial hypoplasia had 3D cone-beam(CB)CT scans taken,and biomimetic upper appliances(DNA appliance■,Vivos Therapeutics,Inc.,USA)were *** subjects were instructed to wear the device 12-16 h/*** month,examination for the progress of midfacial development was ***-treatment,a follow-up 3D CBCT scan was undertaken with no device in the patienfs ***-and post-treatment linear and volumetric measurements were obtained using appropriate software,and compared statistically using ***:The mean age of the sample was 25.0 yrs±*** mean treatment time was 15.5 mths±***-treatment,the transpalatal bone width increased from 35.3 mm±3.0 to 38.5 mm±2.0(P<0.001);the maxillary air sinus volume on the left side increased from 18.8 cm^(3)±6.5 to 20.0 cm^(3)±6.0(P<0.05),and from 18.5 cm^(3)±5.7 to 19.7 cm^(3)±5.8(P<0.05)on the right ***:Biomimetic oral appliance therapy may be able to increase the maxillary air sinus volume in *** view of these preliminary findings,further studies on the effect of enhanced pneumatization on paranasal sinus function and sleep parameters are warranted.

关键词： Pneumatization Maxillary air sinus Biomimetic Oral appliance therapy Palatal expansion

Technical Note on a Track-pattern-based Model for Predicting Seasonal Tropical Cyclone Activity over the Western North Pacific

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Advances in Atmospheric Sciences 2013年第5期30卷 1260-1274页

作者： Chang-Hoi HO Joo-Hong kim Hyeong-Seog kim Woosuk CHOI Min-hee LEE hee-Dong YOO Tae-Ryong kim Sangwook PARK School of Earth and Environmental Sciences Seoul National University Korea Polar Research Institute Atmospheric and Oceanic Science Princeton University and NOAA/GFDL Forecast Policy Division Korea Meteorological Administration National Typhoon Center Korea Meteorological Administration

Recently, the National Typhoon Center （NTC） at the Korea Meteorological Administration launched a track-pattern-based model that predicts the horizontal distribution of tropical cyclone （TC） track density from June to October. This model is the first approach to target seasonal TC track clusters covering the entire western North Pacific （WNP） basin, and may represent a milestone for seasonal TC forecasting, using a simple statistical method that can be applied at weather operation centers. In this note, we describe the procedure of the track-pattern-based model with brief technical background to provide practical information on the use and operation of the model. The model comprises three major steps. First, long-term data of WNP TC tracks reveal seven climatological track clusters. Second, the TC counts for each cluster are predicted using a hybrid statistical-dynamical method, using the seasonal prediction of large-scale environments. Third, the final forecast map of track density is constructed by merging the spatial probabilities of the seven clusters and applying necessary bias corrections. Although the model is developed to issue the seasonal forecast in mid-May, it can be applied to alternative dates and target seasons following the procedure described in this note. Work continues on establishing an automatic system for this model at the NTC.

关键词： tropical cyclone western North Pacific seasonal forecast track-pattern-based model hybrid statistical-dynamical approach

Expression Pattern of the Hippo Pathway Effector TAZ in Cellular and Fibrotic Nonspecific Interstitial Pneumonia

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Chinese Medical Journal 2018年第5期131卷 626-628页

作者： Min-Kyung Yeo hee Sun Park Yeon hee Park choong-Sik Lee Geon Yoo Dong II Park Jeong Eun Lee Jae Young Moon Sung Soo Jung Ju Ock kim Dahyun Kang Hyun Jin Cho Min-Woong Kang Jin-Whan kim Song-Soo kim Chaeuk Chung Department of Pathology Chungnam National University School of Medicine Daejeon 35015 South Korea Division of Pulmonology Department of Internal Medicine Chungnam National University 282 Munhwaro Jung-gu Daejeon 35015 South Korea Department of Internal Medicine Daejeonst Mary's Hospital College of Medicine Catholic University Daejeon 34943 South Korea ~Department of Toxicological Evaluation and Research Korea Institute of Toxicology 141 Gajeong-ro Yuseong-gu Daejeon 34114 South Korea Department of Thoracic Surgery College of Medicine Chungnam National University Daejeon 35015 South Korea Department of Radiology College of Medicine Chungnam National University Daejeon 35015 South Korea Infection Control Convergence Research Center College of Medicine Chungnam National University Jung-guMunhwa-ro 266 Daejeon 35015 South Korea

Interstitial lung disease （ILD） is a comprehensive term referring to a group of lung diseases affecting the interstitium of the lung. Idiopathic pulmonary fibrosis （IPF） is the most common idiopathic ILD, and nonspecific interstitial pneumonia （NSIP） is the second most common. As the name suggests, NSIP is diagnosed atter many other diseases are excluded. The main pathological finding in NSIP is homogeneous interstitial inflammation with or without fibrosis. NSIP can be categorized by cellular type or fibrotic type, according to the grade of inflammation and fibrosis. The cellular type has mostly inflammatory lesions with good responses to steroid, but the fibrotic type has a large proportion of fibrosis mixed with inflammatory lesions and a relatively poor response to steroid treatment So far, the exact mechanism underlying idiopathic lED has not been clarified. Determining key regulators of these ILDs will be helpful in the diagnosis and development of novel drugs for ILD.

关键词： YAP

Accurate Approximation of the Earth Mover's Distance in Linear Time

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Journal of Computer Science & Technology 2014年第1期29卷 142-154页

作者： Min-hee Jang Sang-Wook kim Christos Faloutsos Sunju Park Computer Science Department Carnegie Mellon University ACM IEEE Department of Electronics and Computer Engineering Hanyang University School of Business Yonsei University

Color descriptors are one of the important features used in content-based in, age retrieval. The dominant color descriptor （DCD） represents a few perceptually dominant colors in an image through color quantization. For image retrieval based on DCD, the earth mover＇s distance （EMD） and the optimal color composition distance were proposed to measure the dissimilarity between two images. Although providing good retrieval results, both methods are too time-consuming to be used in a large image database. To solve the problem, we propose a new distance function that calculates an approximate earth mover＇s distance in linear time. To calculate the dissimilarity in linear time, the proposed approach employs the space-filling curve for multidimensional color space. To improve the accuracy, the proposed approach uses multiple curves and adjusts the color positions. As a result, our approach achieves order-of-magnitude time improvement but incurs small errors. We have performed extensive experiments to show the effectiveness and efficiency of the proposed approach. The results reveal that our approach achieves almost the same results with the EMD in linear time.

关键词： earth mover's distance approximation content-based image retrieval

Hepatocellular carcinoma,decompensation,and mortality based on hepatitis C treatment:A prospective cohort study

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World Journal of Gastroenterology 2022年第30期28卷 4182-4200页

作者： Gwang Hyeon Choi Eun Sun Jang Young Seok kim Youn Jae Lee In hee kim Sung Bum Cho Han Chu Lee Jeong Won Jang Moran Ki Hwa Young Choi Dahye Baik Sook-Hyang Jeong Department of Internal Medicine Seoul National University Bundang HospitalSeoul National University College of MedicineSeongnam 13620South Korea Department of Internal Medicine Soonchunhyang University Bucheon HospitalBucheon 14584South Korea Department of Internal Medicine Inje University Busan Paik HospitalBusan 47392South Korea Department of Internal Medicine Chonbuk National University HospitalJeonju 54907JeonbukSouth Korea Department of Internal Medicine Chonnam National University Hwasun HospitalHwasun 58128South Korea Department of Gastroenterology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Internal Medicine The Catholic University of KoreaSeoul 06591South Korea Cancer Control and Population Health Graduate School of Cancer Science and PolicyNational Cancer CenterGoyang 10408South Korea

BACKGROUND Prospective studies of the long-term outcomes of patients with hepatitis C virus(HCV)infection after treatment with interferon-based therapy(IBT)or directacting antivirals(DAA)are limited in many Asian *** To elucidate the incidences of hepatocellular carcinoma(HCC)and death/transplantation based on treatment with IBT or DAA,to compare the outcomes of the sustained virologic response(SVR)to IBT and DAA,and to investigate outcome-determining factors after *** This cohort included 2054 viremic patients(mean age,57 years;46.5%male;27.4%with cirrhosis)prospectively enrolled at seven hospitals between 2007 and *** were classified as the untreated group(n=619),IBT group(n=578),and DAA group(n=857).Outcomes included the incidences of HCC and death/*** incidences of the outcomes for each group according to treatment were calculated using an exact method based on the Poisson distribution.A multivariate Cox regression analysis was performed to determine the factors associated with HCC or death/transplantation,followed by propensity score matching to confirm the *** During a median of 4.1 years of follow-up,HCC and death/transplantation occurred in 113 and 206 patients,respectively,in the entire *** with the untreated group,the incidences of HCC and death/transplantation were significantly lower in the IBT group[adjusted hazard ratio(aHR)0.47,95%CI:0.28-0.80 and aHR 0.28,95%CI:0.18-0.43,respectively]and the DAA group(aHR 0.58,95%CI:0.35-0.96,and aHR 0.19,95%CI:0.20-0.68,respectively).Among 1268 patients who attained SVR with IBT(n=451)or DAA(n=816),the multivariable-adjusted analysis showed no differences in the risks of HCC(HR 2.03;95%CI:0.76-5.43)and death/transplantation(HR 1.38;95%CI:0.55-3.49)between the two *** was confirmed by a propensity score-matching *** factors for HCC after SVR were age,genotype 1,and the presence of *** Treatment and achieving SVR

关键词： Hepatitis C virus Direct-acting antiviral Sustained virologic response Hepatocellular carcinoma Mortality

Super-resolution localization photoacoustic microscopy using intrinsic red blood cells as contrast absorbers

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Light(Science & Applications) 2019年第1期8卷 212-222页

作者： Jongbeom kim Jin Young kim Seungwan Jeon Jin Woo BAIK Seong hee Cho Chulhong kim Departments of Creative IT Engineering Electrical EngineeringMechanical Engineeringand Interdisciplinary Bioscience and BioengineeringPohang University of Science and Technology(POSTECH)77 Cheongam-roNam-guPohangGyeongbuk 37673Republic of Korea

Photoacoustic microscopy(PAM)has become a premier microscopy tool that can provide the anatomical,functional,and molecular information of animals and humans in ***,conventional PAM systems suffer from limited temporal and/or spatial ***,we present a fast PAM system and an agent-free localization method based on a stable and commercial galvanometer scanner with a custom-made scanning mirror(L-PAM-GS).This novel hardware implementation enhances the temporal resolution significantly while maintaining a high signal-to-noise ratio(SNR).These improvements allow us to photoacoustically and noninvasively observe the microvasculatures of small animals and humans in ***,the functional hemodynamics,namely,the blood flow rate in the microvasculature,is successfully monitored and quantified in *** importantly,thanks to the high SNR and fast B-mode rate(500 Hz),by localizing photoacoustic signals from captured red blood cells without any contrast agent,unresolved microvessels are clearly distinguished,and the spatial resolution is improved by a factor of 2.5 in ***-GS has great potential in various fields,such as neurology,oncology,and pathology.

关键词： resolution absorber scanner

Comparison of totally laparoscopic total gastrectomy using an endoscopic linear stapler with laparoscopic-assisted total gastrectomy using a circular stapler in patients with gastric cancer: a single-center experience

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World Journal of Gastroenterology 2017年第48期23卷 8553-8561页

作者： Chung Sik Gong Byung Sik kim hee Sung kim department of gastric surgery asan medical centeruniversity of ulsan college of medicine

AIM To evaluate the safety and efficacy of totally laparoscopic total gastrectomy(TLTG) with esophagojejunostomy using a linear stapler compared with laparoscopic-assisted total gastrectomy(LATG) using a circular stapler in gastric cancer *** We retrospectively reviewed 687 patients who underwent laparoscopic total gastrectomy for gastric cancer at a single institution from August 2008 to August 2014. The patients were divided into two groups according to the type of operation: 421 patients underwent TLTG and 266 underwent LATG. Clinicopathologic characteristics and surgical outcomes in the two groups were compared and *** The TLTG group had higher mean ages at the time of operation(57.78 ± 11.20 years and 55.69 ± 11.96 years,P = 0.020) and more histories of abdominal surgery(20.2% and 12.4%,P = 0.008) compared with the LATG group. Surgical outcomes such as intraoperative and postoperative transfusions,combined operations,pain scores and administration of analgesics,and complications were similar between the two groups. However,compared with the LATG group,the TLTG group required a shorter operation time(149 min vs 170 min,P < 0.001),had lower postoperative hematocrit change(3.49% vs 4.04%,P = 0.002),less intraoperative events(3.1% vs 10.2%,P < 0.001),less intraoperative anastomosis events(2.4% vs 7.1%,P = 0.003),faster postoperative recovery such as median time to first flatus(3.30 d vs 3.60 d,P < 0.001),faster median commencement of soft diet(4.30 d vs 4.60 d,P < 0.001) and shorter length of postoperative hospital stay(6.75 d vs 7.02 d,P = 0.005). CONCLUSION The intracorporeal method for reconstruction of esophagojejunostomy using a linear stapler may be considered a feasible procedure comparing with extracorporeal anastomosis using circular stapler because TLTG is simpler and more straightforward than LATG. Therefore,TLTG can be recommended as an appropriate procedure for gastric cancer.

关键词： Totally laparoscopic total gastrectomy Laparoscopic-assisted total gastrectomy Gastric cancer

Racism,Equity,and Quality of Education for International Students in South Korean Higher Education Institutes

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Frontiers of Education in China 2016年第3期11卷 338-355页

作者： Jin-hee kim Office of Global Education Development and Cooperation Research Korean Educational Development Institute(KEDI)Seoul 06762South Korea

This study aims to understand equity issues of international students’learning in Korean higher education institutions by engaging with the issue of racism and identifies how international students in Korea reshape their learning trajectory and how we could provide equitable and quality education for international *** a qualitative case study design,six students from different background were interviewed to examine features of perceived institutional racism based on their learning experience in *** findings showed that internationalization has not been fulfilled in terms of engaging with international students although Korean government and higher education institutions have developed relevant policy to attract international *** study indicates that Korean universities need to reconstruct their social,cultural,and institutional systems to embrace equity,diversity and inclusiveness to empower international students’capacity.

关键词： diversity equity higher education multicultural education racism

Uncertainty analysis of flow rate measurement for multiphase flow using CFD

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Acta Mechanica Sinica 2015年第5期31卷 698-707页

作者： Joon-Hyung kim Uk-hee Jung Sung kim Joon-Yong Yoon Young-Seok Choi Department of Mechanical Design Engineering Hanyang University Thermal & Fluid System R&BD Group Korea Institute of Industrial Technology Energy System Engineering University of Science and Technology

The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow ***,it has excellent versatility and is being widely applied in many *** flow of a liquid containing air is a representative example of a multiphase flow and exhibits complex flow *** particular,the greater the gas volume fraction（GVF）,the more inhomogeneous the flow *** a result,using a venturi meter to measure the rate of a flow that has a high GVF generates an *** this study,the cause of the error occurred in measuring the flow rate for the multiphase flow when using the venturi meter for analysis by *** ensure the reliability of this study,the accuracy of the multiphase flow models for numerical analysis was verified through comparison between the calculated results of numerical analysis and the experimental *** a result,the Grace model,which is a multiphase flow model established by an experiment with water and air,was confirmed to have the highest ***,the characteristics of the internal flow Held about the multiphase flow analysis result generated by applying the Grace model were analyzed to find the cause of the uncertainty occurring when measuring the flow rate of the multiphase flow using the venturi meter.A phase separation phenomenon occurred due to a density difference of water and air inside the venturi,and flow inhomogeneity happened according to the flow velocity difference of each *** was confirmed that this flow inhomogeneity increased as the GVF increased due to the uncertainty of the flow measurement.

关键词： Multiphase flow Measurement Numerical analysis Venturi meter Gas volume fraction(GVF) Uncertainty Multiphase flow model Grace model