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网络测量中高精度时间戳研究与实现

计算机研究与发展 2010年第12期47卷 2049-2058页

作者：谢应科王建东祝超赵自力韩承德中国科学院计算技术研究所北京100190 中国科学院研究生院北京100049

在网络测量中,时间戳记录数据包接收和发送的时间,是时延、带宽以及抖动等网络参数测量的基础.受缓存延迟、中断响应时间不确定等因素影响,软件时间戳只能达到毫秒级精度;基于GPS(global positioning system)时钟的硬件时间戳可以达到... 详细信息

在网络测量中,时间戳记录数据包接收和发送的时间,是时延、带宽以及抖动等网络参数测量的基础.受缓存延迟、中断响应时间不确定等因素影响,软件时间戳只能达到毫秒级精度;基于GPS(global positioning system)时钟的硬件时间戳可以达到纳秒级精度,但其成本高且安装部署不方便.基于对网络测量系统中时间戳误差来源的详细分析,设计了精确时间戳测量系统,系统利用硬件产生时间戳,消除各种软件延迟影响,通过基于预测的时钟同步算法PCS(prediction-based clock synchronization)同步各测量节点时钟,达到了与GPS相当的精度.基于自行设计的千兆网卡实现了测量系统原型,测试表明各测量节点时间戳误差不超过100ns.

关键词：网络测量时钟同步 GPS 误差时间戳

Understanding Surface Water-Groundwater Conversion Relationship and Associated Hydrogeochemistry Evolution in the Upper Reaches of Luan River Basin, North China

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Journal of Earth Science 2024年第3期35卷 1010-1023页

作者： Le Zhao Chunli Su Wenbo Liu Xianjun xie School of Environmental Studies China University of GeosciencesWuhan 430078China State Environmental Protection Key Laboratory of Source Apportionment and Control of Aquatic Pollution Ministry of Ecology and EnvironmentWuhan 430078China China Geological Environmental Monitoring Institute Beijing 100081China

Luan River is the main water source in Beijing-Tianjin-Hebei region,northern China,where the groundwater system is vulnerable and pollution issue is *** is significant for regional groundwater resources protection to identify the hydrogeochemistry evolution and affecting factors along flow direction occurred in the upper reaches,especially the surface water-groundwater(SWGW)conversion *** this study,recharge,conversion and geochemistry evolution of SW and GW were elucidated based on physical-hydrochemical indicators and stable isotopes in 36 GW samples and 20 SW samples,which were collected in July 2019 and July *** factor analysis was further utilized to determine the main factors responsible for regional hydrogeochemical *** indicate that GW recharged SW in plateau area,and SW and GW recharged each other in typical Alpine valley *** hydrochemical types are HCO3-Ca·Mg and HCO3-Ca,and the hydrochemical evolution is dominated by weathering of silicate and carbonate *** cation exchange adsorption has minor impact on groundwater *** rise of SO42-and NO3-contents in groundwater is related to industrial and agricultural *** main controlling factors of SW hydrochemical components included recharge from groundwater,industrial and mining activities,explaining 90.04%of data ***,water-rock interaction,agricultural and domestic sewage are responsible for GW quality,accounting for 83.38%.

关键词： groundwater water sources conversion relationship hydrogeochemical characteristics evolutional processes water-rock interaction factor analysis Luan River Basin.

Xingnao Kaiqiao needling method for acute ischemic stroke： a meta-analysis of safety and efficacy

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Neural Regeneration Research 2017年第8期12卷 1308-1314页

作者： Zhi-xin Yang Jia-hong xie Ding-ding Liu Department of Traditional Chinese Medicine Chengde Medical University Chengde Hebei Province China Key Laboratory of Traditional Chinese Medicine Research and Development Institute of Traditional Chinese Medicine Chengde Medical University Chengde Hebei Province China School of Traditional Chinese Medicine North China University of Science and Technology Tangshan Hebei Province China

OBJECTIVE： To evaluate the effectiveness and safety of the Xingnao Kaiqiao needling method for treating acute ischemic *** SOURCES： We retrieved relevant randomized controlled trials involving Xingnao Kaiqiao acupuncture for treatment of acute ischemic stroke. The China National Knowledge Infrastructure, Weipu Information Resources System, Wanfang Medical Data System, Chinese Biomedical Literature Database, Cochrane Library, and Pub Med were searched from June 2006 to March *** SELECTION： We analyzed randomized and semi-randomized clinical controlled trials that compared Xingnao Kaiqiao acupuncture with various control treatments, such as conventional drugs or other acupuncture therapies, for treatment of acute ischemic stroke. The quality of articles was evaluated according to the Cochrane Handbook for Systematic Reviews of Interventions（Version 5.1）, and the study was carried out using Cochrane system assessment methods. Rev Man 5.2 was used for the meta-analysis of the included *** MEASURES： The mortality rate, disability rate, activities of daily living（Barthel Index）, and clinical efficacy were ***： Twelve studies met the inclusion criteria for this review. The meta-analysis showed that between Xingnao Kaiqiao acupuncture and the control treatment, Xingnao Kaiqiao acupuncture reduced the disability rate [risk ratio（RR） = 0.51, 95% confidence interval（CI） = 0.27-0.98, z = 2.03, P 〈 0.05], elevated the activities of daily living（weighted mean difference = 12.23, 95% CI： 3.66-20.08, z = 2.80, P 〈 0.005）, and had greater clinical efficacy（RR = 1.61, 95% CI： 1.23-2.09, z = 3.53, P 〈 0.0004）. However, there was no significant difference in mortality rate（RR = 0.61, 95% CI： 0.15-2.45, z = 0.70, P 〉 0.05）. CONCLUSION： The Xingnao Kaiqiao needling method is effective and safe for acute ischemic stroke. However, there was selective bias in this study, and the likelihood of measurement bias is high. Thus, more high-quality randomized

关键词： nerve regeneration Xingnao Kaiqiao needling method acute ischemic stroke meta-analysis systematic review activities of daily living Barthel index mortality disability rate clinical e^cacy neuralregeneration

基于网络的高校数字化视频监控系统的研究与设计

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实验技术与管理 2011年第8期 263-266页

作者：王晓春谢利德睢强梁迎新承德医学院设备处

基于高等院校已建立的高速计算机网络,采用先进的数字视频网络技术,建设了有效、灵活、高扩展性的高校数字化视频监控系统,为学校教学、管理服务。分析了高校数字视频监控系统的具体应用,给出了一个完整的系统设计方案。

关键词：视频监控系统校园网安全管理

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临床教师的科研及教学档案管理系统设计

实验技术与管理 2011年第8期 215-217页

作者：王清河谢利德杜少杰曹凯王岩承德医学院物资管理处

根据临床教师的科研与教学管理评估体系,利用***页面采集大量教师的教学及科研相关信息,并将信息集成于SQL Server 2000数据库内;通过ADO、SQL语言和数据加权方法操作数据库的数据,实现对这些数据审核、统计分析、打印报表并显示临床教... 详细信息

根据临床教师的科研与教学管理评估体系,利用***页面采集大量教师的教学及科研相关信息,并将信息集成于SQL Server 2000数据库内;通过ADO、SQL语言和数据加权方法操作数据库的数据,实现对这些数据审核、统计分析、打印报表并显示临床教师的科研和教学情况等功能;使之更好地服务于医院临床教学管理,为医院的教学管理提供信息化基础。

关键词：医院教学评估体系数据库数据审核

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模拟临床电子病例的医学实习生学习系统设计

实验技术与管理 2011年第8期 269-271页

作者：王清河谢利德刘永平王亮承德医学院物资管理处

设计了模拟临床电子病例的医学实习生学习系统。电子病例学习系统主要采用了COM组件软件技术,通过COM定义了文件数据组件、数据库组件的对象模型及通信接口,完成了数据的传输及安全管理。该系统在实际应用中方便临床实习学生的学习并深... 详细信息

设计了模拟临床电子病例的医学实习生学习系统。电子病例学习系统主要采用了COM组件软件技术,通过COM定义了文件数据组件、数据库组件的对象模型及通信接口,完成了数据的传输及安全管理。该系统在实际应用中方便临床实习学生的学习并深化了医院临床教学改革。

关键词：临床电子病例组件软件技术临床实习系统

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熔盐电解制备硼及金属硼化物的开发前景

材料导报 2008年第6期22卷 58-60页

作者：王旭翟玉春谢宏伟李承德东北大学材料与冶金学院沈阳110004

介绍了单质硼粉及金属硼化物的优良性能和应用前景,国内外制备和生产单质硼粉及金属硼化物的方法与原理。结合国内外实验与研究的现状,分析认为,熔盐电解法制备与生产单质硼粉及金属硼化物的优点是环境友好、反应条件容易控制、产品纯度... 详细信息

介绍了单质硼粉及金属硼化物的优良性能和应用前景,国内外制备和生产单质硼粉及金属硼化物的方法与原理。结合国内外实验与研究的现状,分析认为,熔盐电解法制备与生产单质硼粉及金属硼化物的优点是环境友好、反应条件容易控制、产品纯度高,是很有前途的方法。现存的主要问题是电极反应机理以及连续电解设备的开发,随着研究工作的深入开展,熔盐电解法的应用前景将非常广阔。

关键词：硼硼化物熔盐电解法

In Silico search and biological validation of MicroR171 family related to abiotic stress response in mulberry(Morus alba)

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Horticultural Plant Journal 2022年第2期8卷 184-194页

作者： Zhichao Sun R.M.Saravana Kumar Jisheng Li Guiming Yang Yan xie Hebei Universities R&D Center for Sericulture and Specialty Enabling Technologies Chengde 067000China Sericultural Research Insitute Chengde Medical UniversityChengde 067000China

miR171 belongs to a highly conserved and ubiquitously expressed micro RNA gene family across species that play a critical role in controlling plant growth and development through the regulation of the miR171-SCL(scarecrow-like proteins)*** is limited research available on the evolutionary relationship and functional diversification of miR171 *** this study,we identified eight miR171 genes in the mulberry genome by bioinformatics analysis that were subsequently used to compare the evolutionary levels and explore abiotic stress mechanisms mediated by mno-miR171s(Morus notabilis miR171s).The results of phylogenetic analysis showed that the mature mno-miR171 sequences have strong sequence conservation,but their critical sites also exhibit high variation leading to functional *** quantitative real-time PCR,the expression profile of each mno-miR171 was analyzed under different stress *** mno-miR171s,apart from mnomiR171h,were found to be significantly up-regulated under salt and drought stress *** target genes of mno-miR171a namely,Morus020885 and Morus011800,were predicted and verified using the plural RNA method.5-rapid amplification of complementary DNA ends assays further to reveal that the target genes could be degraded by mno-miR171a *** of mno-miR171a in Arabidopsis improved the percentage of seed germination when the seeds were grown in NaCl-and mannitol-containing *** plants were observed to grow better under drought *** expression of various stress genes was significantly higher in transgenic plants than in wild type,except *** together,our study confirmed that mno-miR171a enhanced plant resistance to adverse stress environments via the regulation of the SCL targets.

关键词： Mulberry miR171 qRT-PCR SCL Arabidopsis Stress

Localization of ANP-synthesizing cells in rat stomach

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World Journal of Gastroenterology 2006年第35期12卷 5674-5679页

作者： Chun-Hui Li Li-Hui Pan Chun-Yu Li Chang-Lin Zhu Wen-xie Xu Department of Pathology Affiliated Hospital of Chengde Medical College Chengde 067000 Hebei Province China Department of Microbiology and Immunology Chengde Medical College Chengde 067000 Hebei ProvinceChina Department of Surgery Affiliated Hospital for Anus and Intestines Diseases Hospital of Chengde Medical CollegeChengde 067000 Hebei Province China Department of Physiology College of MedicineShanghai Jiaotong University Shanghai 200030 China

AIM: To study the morphological positive expression of antrial natriuretic peptide (ANP)-synthesizing cells and ultrastructural localization and the relationship between ANP-synthesizing cells and microvessel density in the stomach of rats and to analyze the distribution of the three histologically distinct regions of ANP-synthesizing cells. METHODS: Using immunohistochemical techniques, we studied positive expression of ANP-synthesizing cells in rat stomach. A postembedding immunogold microscopy technique was used for ultrastructural localization of ANP-synthesizing cells. Microvessel density in the rat stomach was estimated using tannic acid-ferric chloride (TAFC) method staining. Distribution of ANP-synthesizing cells were studied in different regions of rat stomach histochemically. RESULTS: Positive expression of ANP-synthesizing cells were localized in the gastric mucosa of rats. Localization of ANP-synthesizing cells identified them to be enterochrochromaffin cells (EC) by using a postembedding immunogold electron microscopy technique. EC cells were in the basal third of the cardiac mucosa region. ANP-synthesizing cells existed in different regions of rat stomach and its density was largest in the gastric cardiac region, and the distribution order of ANP-synthesizing cells in density was cardiac region, pyloric region and fundic region in mucosa layer. We have also found a close relationship between ANP-synthesizing cells and microvessel density in gastric mucosa of rats using TAFC staining. CONCLUSION: ANP-synthesizing cells are expressedin the gastric mucosa. EC synthesize ANP. There is a close relationship between ANP-synthesizing cells and microvessel density in gastric mucosa of *** distribution density of ANP-synthesizing cells is largest in the gastric cardiac region.

关键词： Antrial natriuretic peptide-synthesizing cells Microvessel density Close relationship Gastric cardiac region