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社会组织理性化实践及其制度根源：一项长时段案例研究

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中南大学学报（社会科学版） 2019年第6期25卷 136-145页

作者：宋程成华东师范大学公共管理学院

社会组织的理性化现象,可被视为是源自商业领域的管理主义逻辑塑造组织内部管理实践、并迫使其在结构上趋向“企业化”的一系列过程及其结果。通过对浙江省杭州市M组织在养老服务领域14年发展历程的纵向追踪发现:制度环境的复杂性以及... 详细信息

社会组织的理性化现象,可被视为是源自商业领域的管理主义逻辑塑造组织内部管理实践、并迫使其在结构上趋向“企业化”的一系列过程及其结果。通过对浙江省杭州市M组织在养老服务领域14年发展历程的纵向追踪发现:制度环境的复杂性以及制度逻辑的演变是社会组织理性化发展的重要根源;场域内各个制度逻辑通过影响组织形式(治理结构和权力分布),来制约或促进组织内部管理结构的理性化程度及其与实际行为之间的“耦合”度;在这个过程中,管理人员的组织认同也会有所转变,并对组织吸纳理性化要素有所影响。综合上述发现,从组织基础的角度,就公益“新前沿”的前景进行探讨。

关键词：制度环境社会组织变迁理性化

从公益创投到创造性治理--基于江南县实践的制度分析

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公共管理学报 2021年第1期18卷 90-101,172页

作者：宋程成华东师范大学公共管理学院上海200062 华东师范大学社会组织与社会治理创新研究中心上海200062

公益创投通常被认定为撬动地方性社会组织发展的政策工具,其潜在的治理意涵一直未能获得重视。江南县公益创投实践经验表明,基层政策行动者完全有可能通过"创造性治理"来化解新时期的县域社区问题。基于组织学新制度主义,创造性治理可... 详细信息

公益创投通常被认定为撬动地方性社会组织发展的政策工具,其潜在的治理意涵一直未能获得重视。江南县公益创投实践经验表明,基层政策行动者完全有可能通过"创造性治理"来化解新时期的县域社区问题。基于组织学新制度主义,创造性治理可被视为是某一制度形式移植到新的公共政策场景后逐步实现"本地化"的相应过程。案例分析结果显示,公益创投实践在江南县社区中发生了从"杠杆"到"管道"的功能转变,这一转变表明政策行动者可基于自身认知的转化,在关键时点进行"转换性创造",从而在立足本地资源和治理条件的情况下实现制度创新。

关键词：创造性治理公益创投管道功能本地化

超越公共行政案例研究中的“定量范式”——与于文轩教授商榷

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中国行政管理 2020年第8期 94-99页

作者：宋程成华东师范大学公共管理学院、社会组织与社会治理创新研究中心上海200062

案例研究因适用于分析中国转型期间的各类实质性政治社会问题而为公共行政学界所广泛认可和运用。围绕着立足本土经验的案例研究能否科学识别问题、对已有理论作出贡献等议题,学者们在近年来展开了一系列论争。最新关于如何推进中国公... 详细信息

案例研究因适用于分析中国转型期间的各类实质性政治社会问题而为公共行政学界所广泛认可和运用。围绕着立足本土经验的案例研究能否科学识别问题、对已有理论作出贡献等议题,学者们在近年来展开了一系列论争。最新关于如何推进中国公共行政案例研究的相关论述,存在着遵循量化研究随机抽样原则和沿用强势学科信效度评判指标的危险。针对这一趋势,有必要在重新审视案例研究重视实质性问题这一比较优势的基础上,就中国公共行政研究者如何开展案例研究进行再思考。一般而言,为超越"定量范式",公共行政案例研究者可以从数据收集的"结构化"和分析过程的"可比较"出发,在避免忽略竞争性假设的同时,着力于提出具有一般化意义的发现,进而形成自身特有的研究风格。

关键词：案例研究法依因变量选择分析性叙述结构化数据一般化

STUDY ON THE NON-COVALENT INTERACTION OF APIGENIN MOLECULARLY IMPRINTED POLYMERS BY SPECTROMETRY

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Chinese Journal of Reactive Polymers 2008年第1期17卷 66-73页

作者： GUO Lifei HE Minqiang CHEN Yongqiang song chengcheng WAN Jincheng LI Chunxiang School of Chemistry and Chemical Engineering Jiangsu University Zhenjiang 212013 China

The non-covalent interaction between apigenin (API) and different functional monomers (α-methylacrylic acid (MAA), acrylamide (AM), 2-vinylpyridine (2-Vpy) and combined functional monomers (AM/2-Vpy)) was determined by UV spectrometry, and a series of apigenin molecularly imprinted polymers (API-MIPs) was synthesized with different functional monomers through molecular imprinting technology. The relationship between the non-covalent interaction of template/functional monomer and absorption of MIPs also was studied. The results showed that the order of the strength of the non-covalent interaction between API and different functional monomers in tetrahydrofuran (THF) is as follows: 2-Vpy> AM/2-Vpy>AM>MAA, which is positive correlation to the absorption capability of corresponding MIPs, and 2-Vpy is the optimum functional monomer among the used monomer for preparing API- MIPs.

关键词： Apigenin Molecularly imprinted polymers Non-covalent interaction UV spectrometry.

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胰腺病学杂志(英文) 2024年第2期07卷 119-130页

作者： Wang chengcheng Chen Yuan Yin Xinpeng Xu Ruiyuan Ruze Rexiati song Jianlu Hu Chenglin Zhao Yupei Key Laboratory of Research in Pancreatic Tumor Chinese Academy of Medical Sciences Beijing P.R. China National Infrastructures for Translational Medicine Peking Union Medical College Hospital Beijing P.R. China State Key Laboratory of Complex Severe and Rare Diseases Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing P.R. China Institute of Clinical Medicine Peking Union Medical College Hospital Beijing P.R. China Department of General Surgery Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing P.R. China

Objective: Pancreatic cancer is one of the most aggressive malignancies, a robust prognostic signature and novel biomarkers are urgently needed for accurate stratification of the patients and optimization of clinical ***: A list of bioinformatic analysis were applied in public dataset to construct an immune-related signature. Furthermore, the most pivotal gene in the signature was identified. The potential mechanism of the core gene function was revealed through GSEA, CIBERSORT, ESTIMATE, immunophenoscore (IPS) algorithm, single-cell analysis, and functional ***: An immune-related prognostic signature and associated nomogram were constructed and validated. Among the genes constituting the signature, interleukin 1 receptor type II (IL1R2) was identified as the gene occupying the most paramount position in the risk signature. Meanwhile, knockdown of IL1R2 significantly inhibited the proliferation, invasion, and migration ability of pancreatic cancer cells. Additionally, high IL1R2 expression was associated with reduced CD8+ T cell infiltration in pancreatic cancer microenvironment, which may be due to high programmed cell death-ligand-1 (PD-L1) expression in cancer cells. Finally, the IPS algorithm proved that patients with high IL1R2 expression possessed a higher tumor mutation burden and a higher probability of benefiting from ***: In conclusion, our study constructed an efficient immune-related prognostic signature and identified the key role of IL1R2 in the development of pancreatic cancer, as well as its potential to serve as a biomarker for immunotherapy efficacy prediction for pancreatic cancer.

关键词： CD8+ T cells IL1R2 Immunotherapy Pancreatic cancer Tumor microenvironment

A highly sensitive and selective fluorescence probe for singlet oxygen based on paeoniflorin

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A highly sensitive and selective fluorescence probe for sing...

Multiple Social Networks in Grassroots Governance in Rural China

第十届全国化学生物学学术会议

作者： Manman Li chengcheng song Jintao Zhang Huaixia Yang Yanju Liu Pharmacy College Henan University of Chinese Medicine

Creatures produce a lot of reactive oxygen species(ROS) in the metabolic process, and many diseases, deterioration, organism aging and many normal physiological processes are closely related to these free radicals, Singlet oxygen(O) is one of the most important[1]. Singlet oxygen in the body involved in a variety of physiological activities, and in the signal transduction, nerve transmission, muscle tension regulation, peristalsis and platelet healing and so have a very important role. But because O is a strong electrophilic reagent and it can react with some biological molecules such as amino acids, proteins, enzymes and nucleic acids leading to the body’s injury that lead to cell necrosis and cause serious chronic diseases[2]. Detecting singlet oxygen usually use these methods: spectrophotometry, HPLC, fluorescence spectrophotometry,chemiluminescence and electron spin resonance(ESR). The principle of spectrophotometry and fluorescence spectroscopy are to detect the absorbance or fluorescence intensity of the probe changing with the singlet oxygen[3]. Paeoniflorin is an active ingredient of white peony root and belongs to monoterpenoidglucoside compound. It was found that paeoniflorin has the effect of anti-free radical damage and *** has been studied as singlet oxygen probe by fluorescence spectroscopy, the results indicated that paeoniflorin acted as a highly sensitive and selective fluorescent probe for singlet oxygen in aqueous, resulting in 6.25-fold enhancement in neutral medium, and 9.95-fold decrease in alkaline medium, the detection limit is 2.6 and 38.7μM respectively, and the rate constant of the neutral condition was 1.3×10 mol·L·s, Results indicate that paeoniflorin holding great potential to be used as a probe for singlet oxygen in cells with high sensitivity and selectivity.

关键词： singlet oxygen fluorescentprobe paeoniflorin

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Social Sciences in China 2018年第3期39卷 26-45页

作者：徐林宋程成王诗宗龚华燕 School of Public Affairs Zhejiang University School of Public Administration East China Normal University

Existing research on grassroots rural governance in China adopts a network perspective to explore the role of traditional social vehicles including clans,clan clusters and popular beliefs in improving village ***,most of this research has concentrated on analyzing the way in which horizontal network relationships lead to effective village *** has thus to some extent neglected the basic reality of the overlapping interconnections between the ＂top-down＂ administrative system and the informal structure of village *** fact,an analysis that proceeds from the features of the government＇s own organizational network,the social structure of the village itself and the position of its elites in order to focus on modes of interaction within the village under the intermixture of（formal） system design and（informal） social relations,shows that differences in the composition of the government＇s promotional networks resulting from the traits of keyofficials affect the speed of policy dissemination as well as the government＇s mode of interaction with the village ***,differences in these modes of interaction further influence the subsequent operation of self-organization based on social traditions（＂filial piety＂ or ＂morality＂）.At the same time,structural elements,including the economic and social relations of the village itself,determine whether self-organization will improve the quality of governance in the long *** finding can serve as a reflection on and critique of the theories of ＂strong government＂ and ＂tradition＂ current in academia.

关键词： multiple social networks village elite filial piety fund policy dissemination

An Institutional Analysis of the Multi-layered Characteristics of Social Organizations in China

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Social Sciences in China 2016年第4期37卷 93-116页

作者：王诗宗宋程成许鹿 Li Cunna School of Public Affairs Zhejiang University School of Public Administration Guizhou University

The actual state of affairs of Chinese social organizations and the latest theoretical findings on the subject indicate that independence and autonomy are concepts that are interrelated but not fundamentally interchangeable; their actual organizational relationship is complex and varied. Exploration of the relationship between the two concepts is a necessary step in the construction and improvement of a rule-based interpretation of the characteristics of Chinese social organizations. Combining resource dependence theory with the institutional logics perspective enables us to analyze the multiple mechanisms influencing the relationship between independence and autonomy at the organizational level and to test for these mechanisms using a mixed methods research design. Our empirical findings indicate that social organizations gain greater autonomy when they have greater independence from government resources and when they strongly identify, structurally and behaviorally, with classical third sector theory. Organizations＇ behavioral identification can regulate the relationship between independence and autonomy. Further case studies support the value of the above findings. This shows that other mechanisms can often replace, offset or constrain the effects of resource dependence. In the real world, no single fixed theory can cover the independence-autonomy relationship.

关键词： independence resource dependence institutional logic autonomy analysis ofmechanism

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企业与非营利组织社会联盟实施战略分析

管理学报 2015年第7期12卷 984-992页

作者：尹珏林宋程成西交利物浦大学西浦国际商学院浙江大学公共管理学院

依托资源依赖、组织学习、新制度主义等视角,在识别企业与非营利组织社会联盟构成维度和类型的基础上,探索了企业与非营利组织社会联盟实施战略的决策依据和过程,构建"初始条件-治理过程-联盟绩效"的整体研究框架,并识别出可能影响联盟... 详细信息

依托资源依赖、组织学习、新制度主义等视角,在识别企业与非营利组织社会联盟构成维度和类型的基础上,探索了企业与非营利组织社会联盟实施战略的决策依据和过程,构建"初始条件-治理过程-联盟绩效"的整体研究框架,并识别出可能影响联盟战略实施的情境特征。

关键词：社会联盟企业社会责任非营利组织初始条件治理过程联盟绩效