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Traditional Chinese manual acupuncture for management of obesity: A systematic review

World Journal of Meta-Analysis 2015年第5期3卷 206-214页

作者： Kang Xiao Li Angela Weihong Yang charlie cl xue George Binh Lenon Traditional and Complementary Medicine Research Program Health Innovations Research Institute School of Health Sciences RMIT University

AIM： To evaluate the effectiveness and safety ofacupuncture for the treatment of obesity by reviewing currently available randomised controlled ***： This review followed the Cochrane Hand-book for Systematic Reviews of Interventions. Fifteen English and three Chinese databases were searched from their respective inceptions until July 2014. Key words used in the search consisted of acupuncture, needles, obesity, overweight, randomised trial and their synonyms. The risk of bias of included studies was assessed. The differences in effect size between acupuncture and control （including sham, no treatment, western medicine and dietary therapy/exercise） groups were compared using Cochrane Collaboration’s RevMan5.3 ***： Two thousand six hundred and twenty-one records were identifed; after full-text articles assessed for eligibility, 9 of them met inclusion criteria. Majority of included studies had unclear or high risk of bias across all domains. All included studies had high or unclear risk of bias in randomisation, blinding and outcome data. Meta-analysis showed that acupuncture was more effective for reducing body weight and body mass index than no treatment group. Manual acupuncture was also superior to dietary therapy alone for decreasingbody weight. With dietary therapy as co-intervention, combined acupuncture group achieved lower body mass index than combined sham acupuncture group or dietary therapy alone group at the end of treatment period. No severe adverse events from acupuncture group were reported from all included ***： Due to the poor quality of included studies the effectiveness of acupuncture cannot be concluded. Better-designed, large-scale, randomised, sham-controlled clinical trials with long-term follow-up are needed.

关键词： Acupuncture Obesity Weight loss Over-weight Body weight Body mass index Randomised clinical trial

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Acupuncture Combined with Chinese Herbal Medicine for Seasonal Allergic Rhinitis: A Randomized Controlled Trial

Acupuncture Combined with Chinese Herbal Medicine for Season...

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第二次世界中西医结合大会

作者： charlie cl xue Francis CK Thien JerryJSZhang cliffDaCosta ChunG.Li The Chinese Medicine Research Group RMIT UniversityBundoora West CampusAustralia The Alfred Hospital and Monash University PrahranAustralia The Chinese Medicine Research Group RMIT UniversityBundoora West CampusAustralia The Chinese Medicine Research Group RMIT UniversityBundoora West CampusAustralia The Chinese Medicine Research Group RMIT UniversityBundoora West CampusAustralia

＜正＞ Objective:To determine whether Chinese herbal medicine（CHM）produces an additional effect toacupuncture in the symptomatic management of seasonal allergic rhinitis（SAR）.Methods:Randomized,double-blinded,placebo-controlled trial for Chinese herbal medicine concurrent real acupuncture treatment wererecruited through Chinese medicine clinic at RMIT University in 1999.65 *** SAR were assigned to

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Evidence-based clinical Chinese Medicine:What Has Changed Over the Past 20 Years

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广州中医药大学学报 2024年第10期41卷 2555-2567页

作者： charlie Changli xue Anthony Lin Zhang Brian H May Louise Pobjoy Iris Wenyu Zhou RMIT University MelbourneAustralia

Chinese medicine has been used for centuries to treat a range of health *** history has produced a wealth of classical literature,case studies and clinical research data detailing its use and ***,high-quality and conclusive evidence that meets modern requirements for clinical decision support is *** evidence gap limits the integration of Chinese medicine with contemporary medicine,which in turn limits global access and acceptance of Chinese medicine as a form of safe and effective health *** the past 20 years,researchers and organisations around the world,including the World Health Organization(WHO)and United Nations,have worked to support the integration of traditional medicines,such as Chinese medicine,with conventional medicines to improve global health *** paper provides an overview of Chinese medicine studies published in the top four general medical journals(BMJ,JAMA,Lancet and New England Journal of Medicine)from February 2005 to February 2024 in the past 20 years to highlight the progress in the development of this evidence *** also highlights key actions taken to promote evidence-based clinical Chinese medicine,including product and practitioner regulation,formalising education standards,and international *** conducted at the China-Australia International Research Centre for Chinese Medicine demonstrates the benefits of such a *** development of its unique and inclusive‘whole-evidence’approach,plus clinical studies and systematic reviews,the Centre has significantly contributed to the evidence base for clinical Chinese *** addition,its high-impact papers and groundbreaking monographs have been cited in international conventional medicine *** progress has certainly been made during the past 20 years to build a stronger evidence base for clinical Chinese medicine,there is still a considerable gap that limits its integration with conventional medic

关键词： evidence-based medicine traditional Chinese medicine whole-evidence approach integrated traditional Chinese and western medicine integrative medicine China-Australia International Research Centre for Chinese Medicine

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Shennan Road and the modernization of Shenzhen architecture

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Frontiers of Architectural Research 2020年第2期9卷 437-449页

作者： Cong Sun charlie Q.L.xue Department of Architecture and Civil Engineering City University of Hong KongHong KongChina

Shenzhen exemplifies the rapid development of urban planning and construction in *** the last 40 years,many representative urban spaces and buildings have been built on Shennan Road,the city’s main eastewest thoroughfare,which has witnessed the formation of a multicenter structural layout and the miraculous expansion of the *** iconic buildings were designed by Hong Kong or foreign *** continuous development along Shennan Road not only symbolizes the fruits of the reform and opening up policies of Shenzhen and even China,but also reflects the modern architectural history in *** study uses historical research methods to review the changes in the urban fabric and the design trends,as seen in representative buildings along Shennan Road in different *** addition to the transition path of the city center,the unique role of streets and buildings in the development of the urban structure is analyzed,and other urban functions and symbolic meanings are *** work contributes to the history and theory of the modernization of contemporary Chinese architecture.

关键词： Shenzhen architecture Shennan road Contemporary Chinese architecture Foreign design Rapid urbanization

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Accelerating the comprehensive and systematic evaluation of clinical evidence for Chinese medicine using a whole-evidence approach

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Global Health Journal 2019年第2期3卷 33-36页

作者： charlie Changli xue Yubo Lyu The China-Australia International Research Centre for Chinese Medicine School of Health and Biomedical SciencesRMIT UniversityP.O.Box 71BundooraVictoria 3083Australia Guangdong Provincial Hospital of Chinese Medicine 111 Dade RoadGuangzhou 510000China

Modern Chinese medicine is rooted in classical literature and the legacies provided by ancient doctors and their *** is also grounded in the practices of expert clinicians and increasingly informed by clinical and experimental *** Chinese medicine's stage of international development,a whole-evidence approach is an appropriate method for compiling and synthesizing different types and levels of evidence for specific types of *** approach can be used for the wide range of clinical conditions that Chinese medicine commonly treats.

关键词： Chinese medicine Whole-evidence approach Evidence-based medicine

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Performing arts buildings in Taiyuan:Cultural history buildings in a second-tier Chinese city

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Frontiers of Architectural Research 2019年第2期8卷 215-228页

作者： Yingbo Xiao Yan Wan charlie Q.L.xue Department of Architecture and Civil Engineering City University of Hong KongHong KongChina

In the twenty-first century,Chinese cities tend to rely on cultural megastructures to define their new districts and reflect their aspirations.A grand theater,which is a complicated building type in terms of technology and has a striking image,is a central attraction and the focus of a new *** paper focuses on Taiyuan City,a second-tier Chinese city with a brilliant history that has been gradually reduced to *** paper aims to reveal the relationship among productivity,urban development,and theater construction in different historic periods;highlights the initiation,design,and implication of the latest grand theater designed by a French firm;and investigates the city and its performing arts spaces,stakeholders,and various forces that make the theater and its urban *** affective forces may be typical in Central China,which is a generally backward area compared with the entire *** paper presents proper descriptors for performing arts buildings in Taiyuan for three generations,and the lessons from Taiyuan can provide references for other cities that face similar problems and challenges.

关键词： The Shanxi grand theatre Performing art space Importation of design International architecture

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Preparation and characterisation of solid dispersions of tanshinone ⅡA, cryptotanshinone and total tanshinones

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Asian Journal of Pharmaceutical Sciences 2017年第1期12卷 85-97页

作者： Xifeng Zhai Chunguang Li George Binh Lenon charlie C.L.xue Weize Li Traditional&Complementary Medicine Program School of Health SciencesRMIT UniversityBundooraVictoriaAustralia School of Pharmaceutical Sciences Xi’an Medical UniversityXi’anChina Center for Complementary Medicine Research National Institute of Complementary MedicineUniversity of Western SydneyCampbelltown CampusPenrithNew SouthWalesAustralia

Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza *** ⅡA and cryptotanshinone are the major components in total ***, the bioavailability of both compounds is low due to poor water solubility. To enhance the solubility and dissolution rate of tanshinone ⅡA, cryptotanshinone and total tanshinones,three common used hydrophilic carriers including PEG 6000, poloxamer 188 and PVP K30 were used to prepare the solid dispersions at different ratios, respectively. The solid dispersions were characterised by scanning electron microscopy(SEM), differential scanning calorimetry(DSC) and Fourier transform infrared spectroscopy(FTIR). The results of powder X-ray diffraction confirmed the microcrystal state of total tanshinones in solid dispersions and no chemical interaction between total tanshinones and carriers was observed in FTIR spectra. The solubility and dissolution rate of tanshinone ⅡA and cryptotanshinone were significantly increased in all solid dispersions. Regarding tanshinone ⅡA, the solubility and dissolution rate of in solid dispersions prepared with poloxamer 188 were significantly higher than that with PEG 6000 and PVP K30. The higher solubility and dissolution rate of cryptotanshinone were obtained in solid dispersion of PVP K30 than that of PEG 6000 solid dispersions but no significant difference from poloxamer 188 solid dispersions. The results indicate that the superior carrier for preparation of tanshinone ⅡA and total tanshinones solid dispersions is poloxamer 188, and that for cryptotanshinone is PVP K30.

关键词： Cryptotanshinone Tanshinone ⅡA Total tanshinones Solid dispersion Dissolution rate

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Oral Herbal Medicines for Psoriasis:A Review of clinical Studies

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Chinese Journal of Integrative Medicine 2012年第3期18卷 172-178页

作者： Brian H.May Anthony L.ZHANG 卢传坚 charlie C.L.xue Traditional & Complementary Medicine Research Program Health Innovations Research Institute WHO Collaborating Centre for Traditional Medicine School of Health Sciences RMIT University Guangdong Provincial Academy of Chinese Medical Sciences and Guangdong Provincial Hospital of Chinese Medicine

Various forms of complementary and alternative medicine are used in *** these,herbal medicines are frequently used as systemic and/or topical interventions either as a replacement for or in conjunction with conventional *** benefit of such use is *** review is to provide an up-to-date review and discussion of the clinical evidence for the main kinds of herbal therapies for *** of the biomedical databases PubMed（including MEDLINE）, EMBASE and CINAHL were conducted in December 2011 which identified 32 clinical studies,all published in *** of these primarily tested topical herbal medicines and were thus *** 12 studies that evaluated systemic use of herbal medicines were included in the *** were case series studies and the other 8 were controlled *** terms of interventions,4 studies tested the systemic use of plant oils combined with marine oils and 8 studies tested multi-ingredient herbal *** clinical evidence for plant and animal derived fatty acids is inconclusive and any benefit appears to be *** the multi-herb formulations,benefits of oral herbal medicines were shown in several studies,however,a number of these studies are not controlled trials,a diversity of interventions are tested and there are methodological issues in the controlled *** conclusion,there is promising evidence in a number of the studies of multi-herb ***,well-designed,adequately powered studies with proper control interventions are needed to further determine the benefits of these *** addition,syndrome differentiation should be incorporated into trial design to ensure effective translation of findings from these studies into Chinese medicine clinical practice.

关键词： psoriasis herbal medicine complementary medicine traditional medicine clinical study review

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clinical Observation on Chinese Herbal Medicine in Treatment of Long-term Insomnia

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Chinese Journal of Integrative Medicine 2000年第2期6卷 122-126页

作者： David Wang charlie xue Noel Lim Woei-Jia Jiang Jennifer R Jamison

Objective: To investigate the clinical efficacy of Serenity, an Australia Government listed Chinese herbal patent medicine, in the treatment of long-term ***: Adopting randomized double blind placebo controlled cross-over method, 19 volunteers participated were enrolled in this study for a period of 12 weeks. Each phase of the trial lasted for six weeks. No washout period was implemented. Assessment was based on the Vital Sign Test, Sleep Parameter Questionnaire, Leeds Sleep Evaluation Questionnaire and the Side Effects Questionnaire. Results: Serenity improved significantly the Overall Sleep Evaluation in the treated group, in comparing with that in the control group, Pclinical management of long-term insomnia.

关键词： insomnia sleep disorder Chinese herbal medicine Serenity

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中医干预类临床证据分级系统构建思路探讨

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中医杂志 2023年第18期64卷 1885-1889页

作者：刘少南郭新峰吴大嵘 ZHANG Anthony Lin xue charlie Changli 温泽淮广州中医药大学第二附属医院/广东省中医院广东省广州市510120 省部共建中医湿证国家重点实验室(广州中医药大学第二附属医院) China-Australia International Research Center for Chinese Medicine School of Health and Biomedical SciencesRMIT University 广州中医药大学科技创新中心

证据分级水平是进行临床决策的重要考虑因素。中医药领域完全照搬国际常用证据评价体系存在一定局限性,故提出中医临床证据分级思路,即在遵循国际证据分级标准基础上,充分考虑中医药临床实践特点,以GRADE(Grades of Recommendation,Asse... 详细信息

证据分级水平是进行临床决策的重要考虑因素。中医药领域完全照搬国际常用证据评价体系存在一定局限性,故提出中医临床证据分级思路,即在遵循国际证据分级标准基础上,充分考虑中医药临床实践特点,以GRADE(Grades of Recommendation,Assessment,Development,and Evaluation)证据评价系统为基础,结合中医古籍证据及现代名医经验证据分级标准,进而整合形成中医干预类临床证据分级系统,其中古籍证据从医案来源、诊疗内容的全面性和传承性三方面进行评价,现代名医经验证据根据名医的资质、经验内容完整性、经验传承性进行评价。针对中医古籍、现代名医经验及现代研究多来源证据的整合,以定性综合为主,多来源证据的分级水平与现代研究GRADE证据评价保持一致,而中医古籍及现代名医经验作为辅助证据呈现,以期更加客观、全面地评价中医临床证据,进而指导临床实践。

关键词：干预类临床证据中医古籍名医经验 GRADE

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