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建筑学报 2009年第5期 69-72页

作者：薛求理香港城市大学

概述1978-2008年30年来我国引进外国建筑设计的情况,总结了引进外国建筑设计的正面和负面影响,并展示了对此一专题已经开展的研究。认为在全球化的今天,外国建筑设计会成为中国城市建设中的常态,人们更关注的将是设计质量和品牌。

关键词：输入建筑全球化引进和适应中国当代建筑改革开放

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基于能量模型的曲面展开通用算法

计算机辅助设计与图形学学报 2001年第6期13卷 556-560页

作者：王弘王昌凌华中理工大学动力工程系武汉430074 香港科技大学机械工程系

文中提出一个基于能量模型的曲面展开通用算法 ,解决了复杂曲面的展开问题 .将一个三维曲面展平为与之相对应的二维片 ,在计算机辅助设计、制造及计算机图形学中的纹理映射等方面都有应用 .首先 ,采用三角片模型来表达一个曲面 ;然后 ,... 详细信息

文中提出一个基于能量模型的曲面展开通用算法 ,解决了复杂曲面的展开问题 .将一个三维曲面展平为与之相对应的二维片 ,在计算机辅助设计、制造及计算机图形学中的纹理映射等方面都有应用 .首先 ,采用三角片模型来表达一个曲面 ;然后 ,建立一个基于能量的模型将三维曲面展开为二维片 .在这一过程中 ,曲面展开的局部精度较易控制 ,因此 ,较之以前的方法 ,此方法能更有效地解决

关键词：能量模型曲面展开通用算法 cAD cAM 计算机图形学

comparative analysis of biological characteristics of adult mesenchymal stem cells with different tissue origins

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Asian Pacific Journal of Tropical Medicine 2015年第9期8卷 725-731页

作者： Jin-Yang chen Xiao-Zhou Mou Xiao-chun Du charlie Xiang State Key laboratory for Diagnosis and Treatment of Infectious Diseases the First Affiliated Hospital College of Medicine Zhejiang University clinical Research Institute Zhejiang Provincial People's Hospital S-Evans Biosciences

Objective: To invest the dif erences among mesenchymal stem cells(MScs) derived from different tissues and their impacts on clinical applications. Methods: In this study, MScs were isolated from adipose tissue(AD), umbilical cord tissue(Uc), and menstrual blood(Men) and comparedtheir biological characteristics in terms of proliferation capacity, passage capacity, colony formation, and surface markers were compared. Results: The stem cells(Scs) obtained from different sources were all characterized as MScs, but demonstrated some dif erences. Umbilical cord-derived MScs(UcMScs) were able to overcome density inhibition. The proliferation rate decreased in the order UcMScs> Men Scs> ADScs, while the colony-forming ability decreased in the order Men Scs> ADScs> UcMScs. Based on gene-expression data for MScs from dif erent sources within the same donor, 768 Men Sc genes were found that were specii cally upregulated or downregulated compared with bone marrow-derived MScs and UcMScs, most of which were involved in cell function-related pathways. In addition, Men Scs appeared to be superior in terms of immune inl ammation, stress response, and neural dif erentiation potentials, but weaker in terms of osteogenic and chondrogenic dif erentiation capacities, compared with UcMScs and bone marrow-derived MScs. conclusions: Men Scs have higher extraction ei ciency, colony-forming ability, and long time passage capacity. Although the proliferation capacity is inferior to UcMScs.

关键词： Adipose Umbilical cord Menstrual blood Mesenchymal stem cell

Traditional chinese manual acupuncture for management of obesity: A systematic review

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维普期刊数据库

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World Journal of Meta-Analysis 2015年第5期3卷 206-214页

作者： Kang Xiao li Angela Weihong Yang charlie cl xue George Binh lenon Traditional and complementary Medicine Research Program Health Innovations Research Institute School of Health Sciences RMIT University

AIM： To evaluate the effectiveness and safety ofacupuncture for the treatment of obesity by reviewing currently available randomised controlled ***： This review followed the cochrane Hand-book for Systematic Reviews of Interventions. Fifteen English and three chinese databases were searched from their respective inceptions until July 2014. Key words used in the search consisted of acupuncture, needles, obesity, overweight, randomised trial and their synonyms. The risk of bias of included studies was assessed. The differences in effect size between acupuncture and control （including sham, no treatment, western medicine and dietary therapy/exercise） groups were compared using cochrane collaboration’s RevMan5.3 ***： Two thousand six hundred and twenty-one records were identifed; after full-text articles assessed for eligibility, 9 of them met inclusion criteria. Majority of included studies had unclear or high risk of bias across all domains. All included studies had high or unclear risk of bias in randomisation, blinding and outcome data. Meta-analysis showed that acupuncture was more effective for reducing body weight and body mass index than no treatment group. Manual acupuncture was also superior to dietary therapy alone for decreasingbody weight. With dietary therapy as co-intervention, combined acupuncture group achieved lower body mass index than combined sham acupuncture group or dietary therapy alone group at the end of treatment period. No severe adverse events from acupuncture group were reported from all included ***： Due to the poor quality of included studies the effectiveness of acupuncture cannot be concluded. Better-designed, large-scale, randomised, sham-controlled clinical trials with long-term follow-up are needed.

关键词： Acupuncture Obesity Weight loss Over-weight Body weight Body mass index Randomised clinical trial

Hardrock burst mechanisms and management strategies

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维普期刊数据库

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Geohazard Mechanics 2023年第1期1卷 18-31页

作者： Graham Swan charlie c.li Private consultant OntarioCanada Norwegian University of Science and Technology(NTNU) TrondheimNorway

Rockbursts occur as a direct consequence of underground mining or civil *** general scale of their seismic disturbance and consequences depend upon known ***,uncertainty remains as to exactly when and where rockbursts will occur,as well as the effectiveness of ground support measures to fully mitigate their *** the uncertainty in when and where is a dilemma shared with earthquake prediction,that associated with ground support capability is both a design and a management *** a brief review of the known mechanisms that produce rockbursts,the paper explores the sources and scales of energy demands that characterize the risk of their damaging consequences upon underground *** note that some of this risk continues to be associated with uncertainty with respect to rockmass properties and in situ stress,particularly in the context of deep mining.A review is presented of all available yielding ground support systems and their necessary design requirements,identifying practical weaknesses and limitations where these are *** paper concludes with some suggested areas where further study and development could provide the ways and means to reduce the design uncertainty in managing rockbursts.

关键词： Rockbursts Yielding support Seismic energy Managing design uncertainty

Genotype variations in accumulation of cadmium and lead in celery （Apium graveolens l.） and screening for low cd and Pb accumulative cultivars

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维普期刊数据库

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Frontiers of Environmental Science & Engineering 2013年第1期7卷 85-96页

作者： Kun ZHANG Jianbing WANG Zhongyi YANG Guorong XIN Jiangang YUAN Junliang XIN charlie HUANG State Key laboratory for Biocontrol School of Life Sciences Sun Yat-sen University Guangzhou 510275 China california Department of Fish and Game/OSPR/Scientific Division Sacramento CA 94244-2090 USA

To help reduce risks of heavy metal pollution, two pot experiments were conducted to investigate the variations, transfer potential, and stability of cadmium (cd) and lead (Pb) accumulations in celery ( l.) and to screen for low cd and Pb accumulative cultivars. The maximum differences in shoot cd concentration were 4.7-fold under low-cd exposure and 3.3-fold under high-cd exposure. These genotype variations in cd accumulation are sufficiently large to help reduce cd contamination risk in soil by using the low-cd-Accumulative genotypes. cd accumulation of the low-cd-Accumulative genotypes is significantly positive correlated with Pb accumulation. Evidence obtained proves that cd and Pb accumulations in celery are stable and genotype-dependent at the cultivar level. The presence of high-Pb contamination in soil promoted cd accumulation in shoots of celery. celery is considered a species with high risks in cd pollution and low risks in Pb pollution. Among the tested cultivars, cv. Shuanggangkangbing (SGKB) had the lowest shoot cd and Pb accumulating abilities, and thus is the most important material for breeding of pollution-safe cultivars (PScs) to minimize cd and Pb accumulations in celery.

关键词： cadmium (cd) accumulation lead (Pb) accumulation celery genotype variation food safety

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功率因数校正的数字控制技术应用研究

南京航空航天大学学报 2007年第2期39卷 164-170页

作者：陈新 charlie Wu W Hutchings 南京航空航天大学航空电源航空科技重点实验室南京210016 8/16Bit Products Division Freescale Semiconductor Inc

以单管Boost型PFc电路作为研究对象,分别针对电流断续、电流临界连续和电流连续3种工作模态,详细讨论了数字控制PFc的实现方法和设计过程,并分别给出了样机实验结果;此外,结合M c 56F 8013的外设资源特点,给出了基于DSP的PFc详细的系统... 详细信息

以单管Boost型PFc电路作为研究对象,分别针对电流断续、电流临界连续和电流连续3种工作模态,详细讨论了数字控制PFc的实现方法和设计过程,并分别给出了样机实验结果;此外,结合M c 56F 8013的外设资源特点,给出了基于DSP的PFc详细的系统接口设计,包括PWM控制策略和同步控制AD采样环节。对PFc的数字控制方案进行了系统研究,提供了不同工作模式下的完整数字控制解决方案,为功率因数的数字控制技术应用提供了较好的参考作用。

关键词：数字信号处理功率因数校正数字控制 PI控制

clinical Observation on chinese Herbal Medicine in Treatment of long-term Insomnia

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chinese Journal of Integrative Medicine 2000年第2期6卷 122-126页

作者： David Wang charlie xue Noel lim Woei-Jia Jiang Jennifer R Jamison

Objective: To investigate the clinical efficacy of Serenity, an Australia Government listed chinese herbal patent medicine, in the treatment of long-term ***: Adopting randomized double blind placebo controlled cross-over method, 19 volunteers participated were enrolled in this study for a period of 12 weeks. Each phase of the trial lasted for six weeks. No washout period was implemented. Assessment was based on the Vital Sign Test, Sleep Parameter Questionnaire, leeds Sleep Evaluation Questionnaire and the Side Effects Questionnaire. Results: Serenity improved significantly the Overall Sleep Evaluation in the treated group, in comparing with that in the control group, Pc effect reached the peak at the end of the fourth week of the treatment ***: Serenity, a chinese herbal patent medicine,is effective for the clinical management of long-term insomnia.

关键词： insomnia sleep disorder chinese herbal medicine Serenity

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中医干预类临床证据分级系统构建思路探讨

中医杂志 2023年第18期64卷 1885-1889页

作者：刘少南郭新峰吴大嵘 ZHANG Anthony lin xue charlie changli 温泽淮广州中医药大学第二附属医院/广东省中医院广东省广州市510120 省部共建中医湿证国家重点实验室(广州中医药大学第二附属医院) china-Australia International Research center for chinese Medicine School of Health and Biomedical SciencesRMIT University 广州中医药大学科技创新中心

证据分级水平是进行临床决策的重要考虑因素。中医药领域完全照搬国际常用证据评价体系存在一定局限性,故提出中医临床证据分级思路,即在遵循国际证据分级标准基础上,充分考虑中医药临床实践特点,以GRADE(Grades of Recommendation,Asse... 详细信息

证据分级水平是进行临床决策的重要考虑因素。中医药领域完全照搬国际常用证据评价体系存在一定局限性,故提出中医临床证据分级思路,即在遵循国际证据分级标准基础上,充分考虑中医药临床实践特点,以GRADE(Grades of Recommendation,Assessment,Development,and Evaluation)证据评价系统为基础,结合中医古籍证据及现代名医经验证据分级标准,进而整合形成中医干预类临床证据分级系统,其中古籍证据从医案来源、诊疗内容的全面性和传承性三方面进行评价,现代名医经验证据根据名医的资质、经验内容完整性、经验传承性进行评价。针对中医古籍、现代名医经验及现代研究多来源证据的整合,以定性综合为主,多来源证据的分级水平与现代研究GRADE证据评价保持一致,而中医古籍及现代名医经验作为辅助证据呈现,以期更加客观、全面地评价中医临床证据,进而指导临床实践。

关键词：干预类临床证据中医古籍名医经验 GRADE

Multifunctional role of microRNAs in mesenchymal stem cell-derived exosomes in treatment of diseases

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World Journal of Stem cells 2020年第11期12卷 1276-1294页

作者： Hui-Kang Xu li-Jun chen Si-Ning Zhou Yi-Fei li charlie Xiang State Key laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003Zhejiang ProvinceChina

Mesenchymal stem cells can be replaced by exosomes for the treatment of inflammatory diseases,injury repair,degenerative diseases,and *** are small vesicles rich in a variety of nucleic acids[including messenger RNA,long non-coding RNA,microRNA(miRNA),and circular RNA],proteins,and *** can be secreted by most cells in the human body and are known to play a key role in the communication of information and material transport between *** exosomes,miRNAs were neglected before their role in various activities of organisms was *** studies have confirmed that miRNAs play a vital role within *** review focuses on the specific role of miRNAs in MSc-derived exosomes(MSc-exosomes)and the methods commonly used by researchers to study miRNAs in *** together,miRNAs from MSc-exosomes display immense potential and practical value,both in basic medicine and future clinical applications,in treating several diseases.

关键词： MicroRNA Mesenchymal stem cells Exosomes Modulation of mesenchymal stem cells Inflammatory diseases Injury repair