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Data analytics using canonical correlation analysis and monte Carlo simulation

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npj Computational materials 2017年第1期3卷 234-239页

作者： Jeffrey m.Rickman Yan Wang Anthony D.Rollett martin P.Harmer charles Compson Department of Physics Lehigh UniversityBethlehemPA 18015USA Department of materials Science and Engineering Lehigh UniversityBethlehemPA 18015USA Department of materials Science and Engineering Carnegie Mellon UniversityPittsburghPA 15213USA Almatis Inc. LeetsdalePA 15056USA

A canonical correlation analysis is a generic parametric model used in the statistical analysis of data involving interrelated or interdependent input and output *** is especially useful in data analytics as a dimensional reduction strategy that simplifies a complex,multidimensional parameter space by identifying a relatively few combinations of variables that are maximally *** shortcoming of the canonical correlation analysis,however,is that it provides only a linear combination of variables that maximizes these *** this in mind,we describe here a versatile,monte-Carlo based methodology that is useful in identifying non-linear functions of the variables that lead to strong input/output *** demonstrate that our approach leads to a substantial enhancement of correlations,as illustrated by two experimental applications of substantial interest to the materials science community,namely:(1)determining the interdependence of processing and microstructural variables associated with doped polycrystalline aluminas,and(2)relating microstructural decriptors to the electrical and optoelectronic properties of thin-film solar cells based on CuInSe_(2) ***,we describe how this approach facilitates experimental planning and process control.

关键词： canonical analytic absorber

Capabilities and limitations of 3D printed microserpentines and integrated 3D electrodes for stretchable and conformable biosensor applications

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microsystems & Nanoengineering 2020年第1期6卷 1078-1092页

作者： charles Didier Avra Kundu Swaminathan Rajaraman Nanoscience Technology Center(NSTC) University of Central FloridaOrlandoFL 32826USA Burnett School of Biomedical Sciences University of Central FloridaOrlandoFL 32827USA Department of materials Science&Engineering University of Central FloridaOrlandoFL 32816USA Department of Electrical&Computer Engineering University of Central FloridaOrlandoFL 32816USA

We explore the capabilities and limitations of 3D printed microserpentines(µserpentines)and utilize these structures to develop dynamic 3D microelectrodes for potential applications in in vitro,wearable,and implantable microelectrode arrays(mEAs).The device incorporates optimized 3D printedµserpentine designs with out-of-plane microelectrode structures,integrated on to a flexible Kapton®package with micromolded PDmS *** flexibility of the optimized,printedµserpentine design was calculated through effective stiffness and effective strain equations,so as to allow for analysis of various designs for enhanced *** optimized,down selectedµserpentine design was further sputter coated with 7–70 nm-thick gold and the performance of these coatings was studied for maintenance of conductivity during uniaxial strain ***/conforming analysis of the final devices(3D mEAs with a Kapton®package and PDmS insulation)were performed to qualitatively assess the robustness of the finished device toward dynamic mEA applications.3D microelectrode impedance measurements varied from 4.2 to 5.2 kΩduring the bending process demonstrating a small change and an example application with artificial agarose skin composite model to assess feasibility for basic transdermal electrical recording was further demonstrated.

关键词： microelectrode insulation utilize

Applications of advanced signal processing and machine learning in the neonatal hypoxic-ischemic electroencephalography

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Neural Regeneration Research 2020年第2期15卷 222-231页

作者： Hamid Abbasi charles P.Unsworth Department of Engineering Science The University of Auckland

Perinatal hypoxic-ischemic-encephalopathy significantly contributes to neonatal death and life-long disability such as cerebral palsy. Advances in signal processing and machine learning have provided the research community with an opportunity to develop automated real-time identification techniques to detect the signs of hypoxic-ischemic-encephalopathy in larger electroencephalography/amplitude-integrated electroencephalography data sets more easily. This review details the recent achievements, performed by a number of prominent research groups across the world, in the automatic identification and classification of hypoxic-ischemic epileptiform neonatal seizures using advanced signal processing and machine learning techniques. This review also addresses the clinical challenges that current automated techniques face in order to be fully utilized by clinicians, and highlights the importance of upgrading the current clinical bedside sampling frequencies to higher sampling rates in order to provide better hypoxic-ischemic biomarker detection frameworks. Additionally, the article highlights that current clinical automated epileptiform detection strategies for human neonates have been only concerned with seizure detection after the therapeutic latent phase of injury. Whereas recent animal studies have demonstrated that the latent phase of opportunity is critically important for early diagnosis of hypoxic-ischemic-encephalopathy electroencephalography biomarkers and although difficult, detection strategies could utilize biomarkers in the latent phase to also predict the onset of future seizures.

关键词： advanced signal processing aEEG automatic detection classification clinical EEG fetal HIE hypoxic-ischemic encephalopathy machine learning neonatal seizure real-time identification review

Extreme Weather Loss and Damage Estimation Using a Hybrid Simulation Technique

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International Journal of Disaster Risk Science 2022年第4期13卷 592-601页

作者： charles Doktycz mark Abkowitz Hiba Baroud School of Civil and Environmental Engineering Vanderbilt UniversityNashvilleTN 37235USA

History has shown that occurrences of extreme weather are becoming more frequent and with greater impact,regardless of one's geographical *** a risk analysis setting,what will happen,how likely it is to happen,and what are the consequences,are motivating questions searching for *** help address these considerations,this study introduced and applied a hybrid simulation model developed for the purpose of improving understanding of the costs of extreme weather events in the form of loss and damage,based on empirical data in the contiguous United *** results are encouraging,showing on average a mean cost estimate within 5%of the historical *** creates opportunities to improve the accuracy in estimating the expected costs of such events for a specific event type and geographic *** turn,by having a more credible price point in determining the cost-effectiveness of various infrastructure adaptation strategies,it can help in making the business case for resilience investment.

关键词： Climate change Cost estimation Extreme weather Loss and damage Loss normalization monte Carlo simulation

Botanic gardens should lead the way to create a "Garden Earth" in the Anthropocene

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Plant Diversity 2017年第6期39卷 331-337页

作者： charles H.Cannon Chai-Shian Kua The Center for Tree Science The Morton Arboretum Science and Conservation The Morton Arboretum Shanghai Engineering Research Center for Urban Tree Ecology and Applications

The strength and expertise that botanic gardens bring to conservation are based on their detailed knowledge and understanding of the care. management, and biology of a diversity of plant species. This emphasis on the organism has led to many ex-situ and in-situ conservation programs aimed at protecting endangered species, restoring threatened populations, and establishing living plant and seed collections of endangered species. In China, the scale and pace of change in land and resource use, often leading to environmental degradation, has created a strong emphasis on improving environmental conditions. If done properly, being "green" can be a surprisingly complex issue, because it should encompass and exploit the whole of plant diversity and function. Unfortunately, 'green' often includes a small portion of this whole. Earth's rich plant diversity presents considerable opportunity but requires expertise and knowledge for stable and beneficial management. With the dawning of the Anthropocene, we should strive to live on a "Garden Earth", where we design and manage our environments, both built and natural, to create a healthy, beneficial living landscape for people and other organisms. The staff of botanic gardens worldwide and the living collections they maintain embody the best examples of sustainable, beautiful, and beneficial environments that thrive on plant diversity. This expertise should be a fundamental resource for agencies in all sectors responsible for managing and designing "green" infrastructure. Botanic gardens should actively engage and contribute to these opportunities, from large public infrastructure projects to small private conservation efforts. Here, we discuss several ongoing conservation efforts, primarily in China, and attempt to identify areas where botanic gardens could make a significant and meaningful difference.

关键词： Green infrastructure Botanic garden Ex-situ conservationln-situ conservation Botanical garden

multimodal treatment in oligometastatic gastric cancer

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World Journal of Gastrointestinal Oncology 2022年第2期14卷 434-449页

作者： mickael Chevallay charles-Henri Wassmer Pouya Iranmanesh minoa K Jung Stefan P mönig Division of Digestive Surgery Geneva University Hospital and Faculty of MedicineGeneva 1205GenèveSwitzerland

Gastric cancer is generally diagnosed at an advanced stage,especially in countries without screening ***,the metastatic stage was synonymous with palliative management,and surgical indications were only for symptomatic ***,this therapeutic option is associated with poor prognosis.A subgroup of patients with limited metastatic disease could benefit from intensive treatment.A combination of chemotherapy,immunotherapy,and targeted therapy could help either maintain a resectable state for oligometastatic disease or diminish the metastasis size to obtain a complete resection *** latter strategy is known as conversion therapy and has growing evidence with favorable *** approach of metastatic disease could prolong survival in selected *** challenge for the surgeon and oncologist is to identify these specific patients to offer the best multimodal *** review in this article the actual evidence for the treatment of oligometastatic gastric cancer with curative intent.

关键词： Gastric cancer Radiotherapy Chemotherapy multimodal treatment Oligometastatis Immunotherapy

Next generation sequencing, inter-tumor heterogeneity and prognosis of hepatitis B related hepatocellular carcinoma

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Chinese Journal of Cancer Research 2014年第6期26卷 730-731页

作者： Jean-charles Nault Inserm UMR-1162 Génomique fonctionnelle des Tumeurs solidesIUH Paris F-75010 France Université Paris Descartes Labex Immuno-Oncology Sorbonne Paris CitéFaculté de Médecine Paris France Service d'Hépatologie Hopital Jean Verdier AP-HP Bondy and Université Paris 13 Bobigny France

Hepatocellular carcinoma（HCC）is one of the leading causes of cancer related death in Asia and Africa（1）.It reflects the high burden of hepatitis B virus（HBV）infection in these *** treatments of HCC as radiofrequency ablation and resection are impaired by a high rate of tumor ***,most of the time,HCC is frequently diagnosed at advanced stages where only

关键词： sequencing heterogeneity radiofrequency recurrence impaired ablation prognosis carcinogenesis burden Africa

Recent development and challenges in enhancing fire performance on wood and wood-based composites:A 10-year review from 2012 to 2021

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Journal of Bioresources and Bioproducts 2024年第1期9卷 27-42页

作者： charles michael Albert Kang Chiang Liew Faculty of Tropical Forestry Universiti Malaysia SabahKota Kinabalu 88400Kota KinabaluSabah 88400Malaysia

Due to their durability,versatility,and aesthetic value,wood and wood-based composites are widely used as building *** fact that these materials are flammable,however,raises a major worry since they might cause fire hazards and significant loss of life and *** article investigates the variables that affect fire performance as well as the various fire-retardant treatments and their *** current developments and challenges in improving the fire performance of wood and wood-based composites treated with fire-retardant materials are summarized in this ***,organic chemicals,and densification are some recent developments in fire-retardant treatments that are also *** points from the review are summarized,along with potential areas for further research and development.

关键词： Fire performance Fire-retardant materials Wood Wood-based composite Nanoparticles coating Surface charring Bio-based fire retardant Densification

Continuous frequency and phase spectrograms: a study of their 2D and 3D capabilities and application to musical signal analysis

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第2期9卷 199-206页

作者： Laurent NAVARRO Guy COURBEBAISSE Jean-charles PINOLI Ecole Nationale Supérieure des mines de Saint-Etienne Centre Ingénierie et Santé (CIS) and LPMG UMR 5148 CNRS 158 cours Fauriel 42023 Saint-Etienne cedex 2 France medical Imaging Research Center (CREATIS-LRmN) UMR 5220 CNRS U630 INSERM Université Lyon 1 INSA Lyon Bat. Blaise Pascal 7 Av. Jean Capelle 69621 Villeurbanne France

A new lighting and enlargement on phase spectrogram （PS） and frequency spectrogram （FS） is presented in this paper. These representations result from the coupling of power spectrogram and short time Fourier transform （STFT）. The main contribution is the construction of the 3D phase spectrogram （3DPS） and the 3D frequency spectrogram （3DFS）. These new tools allow such specific test signals as small slope linear chirp, phase jump case of musical signal analysis is reported. The main objective is to and small frequency jump to be analyzed. An application detect small frequency and phase variations in order to characterize each type of sound attack without losing the amplitude information given by power spectrogram

关键词： Frequency spectrogram (FS) Phase spectrogram (PS) Time-frequency representations musical signals