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Enhancement of motor functional recovery in thoracic spinal cord injury: voluntary wheel running versus forced treadmill exercise

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Neural Regeneration Research 2025年第3期20卷 836-844页

作者： Do-Hun Lee Dan Cao Younghye Moon chen chen Nai-Kui Liu Xiao-Ming Xu Wei Wu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteIndiana University School of MedicineIndianapolisINUSA Department of Neurological Surgery Indiana University School of MedicineIndianapolisINUSA Department of Neuroscience Baylor College of MedicineHoustonTXUSA

Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.

关键词： behavioral assessment motor function neural plasticity running wheel exercise spinal cord injury treadmill exercise voluntary exercise

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Comprehensive Shape Control Technology for CSP Hot Strip Mills

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International Journal of Automation and computing 2015年第6期12卷 611-619页

作者： chao-chao chen Jian Shao An-Rui He Nan-feng Zhang National Engineering Research Center for Advanced Rolling Technology University of Science and Technology Beijing CSP Hot Strip Mill Hunan Valin Lianyuan Iron & Steel Co. Ltd

With the increasing demand on higher strip quality, the profile and flatness of hot rolling strips have become subjects of concern, particularly for compact strip product(CSP) hot strip mills. Based on the roll contour, control model, and rolling process, a comprehensive shape control technology is proposed and applied to CSP hot strip mill of Lianyuan steel, which includes optimization and design of the work roll contour and varying contact back-up roll(VCR) plus backup roll contour, analysis of the flatness feedback control model, as well as improvement of the rolling process control system. The application of the technology has significantly improved the shape control performance. The roll wear is improved and the general roll consumption of the finishing mill is reduced by 29.86%.The percentages that satisfy the control target ranges of the average strip flatness and crown are increased by approximately 15.40%and 14.82%, respectively. The rejection rate of grade Q235 due to shape quality problem is reduced monthly by 39.69%, which creates significant economic benefits for the plant.

关键词： Compact strip product(CSP) hot strip mills roll co

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Preparation and Performance of Ternary Early Strength Agent and Quercetin Composite Cement Sealing Material

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期 130-140页

作者：刘健 chen Meiting 吉小利 XU chao WANG Chunmei Department of Safety Science and Engineering Anhui University of Science and Technology Key Laboratory of Mine Safety and High Efficient Mining Jointly Built by Province and Education Ministry Anhui University of Science and Technology Department of Chemical Engineering and Explosives Anhui University of Science and Technology

A ternary early-strengthening agent consisting of calcium formate + triethanolamine + lithium sulfate was compounded with quercetin to shorten the setting time of cementitious materials while ensuring their early *** optimum ratio of the three early-strengthening agents was determined as 0.5% calcium formate + 0.04% triethanolamine + 0.4% lithium sulfate by response surface *** effects of the ternary early-strengthening agent composed of calcium formate + triethanolamine(TEA)+ lithium sulfate on cementitious pore sealing materials under the synergistic effect of quercetin were studied by means of the performance tests of compressive strength,fluidity,and setting time,and the microstructural characterizations of X-ray powder diffractometer(XRD),thermogravimetry (TG-DSC) and scanning electron microscopy (SEM).The study shows that the synergistic effect of ternary early-strengthening agent and quercetin forms a multi-performance composite admixture for cementitious *** best performance was obtained with the compounding scheme of 0.5% calcium formate + 0.04% triethanolamine + 0.4% lithium sulfate ternary early-strengthening agent and 0.05% *** compressive strength of 1,3,7,and 28 d are 94.8%,39.8%,42%,and 28% higher than those of the blank group,*** initial time and final setting time are 41 and 57 minutes,*** to the microscopic analysis,the network and fibrous C-S-H gels generated by ternary early-strengthening agents are attached to the surface promoted by quercetin,which forms skeleton support while thickening and solidifying the cement slurry,which enhances the early compressive strength of the cement-based materials.

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Influence of bottom blowing oxygen on dust emission in converter steelmaking

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Journal of Iron and Steel Research International 2021年第9期28卷 1105-1113页

作者： Wei-feng Li Rong Zhu chao feng Bao-chen Han Guang-sheng Wei School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Beijing Key Laboratory of Research Center of Special Melting and Preparation of High-end Metal Materials University of Science and Technology BeijingBeijing 100083China

With the importance of the steelmaking industry in the economy and its negative impacts on the environment,reducing dust emissions is a vital focus in this ***,the theory of dust generation in converter steelmaking process was analyzed and the influence of bottom blowing oxygen on dust generation was obtained through experimental *** industrial test was carried out in a 120-t bottom combined blown O_(2)–CaO steelmaking *** results show that lowering the lance position can reduce the amount of *** emission rate of the converter is also found to be in direct proportion to the decarburization *** a result,the proposed bottom blowing O_(2)–CaO steelmaking converter can technically reduce the amount of dust and improve the recovery rate of *** more bottom blowing oxygen,the dust content is lower with the dust peak appearing *** evaporation theory,followed by the bubble theory,plays the primary role in the dust generation of bottom blowing oxygen *** points out the direction for the technology research and development of reducing dust generation.

关键词： Steelmaking converter Dust emission Bottom blowing O_(2)-CaO Evaporation theory Bubble theory

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Wetting failure condition on rough surfaces

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Chinese Physics B 2019年第4期28卷 242-246页

作者： feng-chao Yang Xiao-Peng chen School of Mechanics Civil Engineering and Architecture Northwestern Polytechnical University School of Marine Science Northwestern Polytechnical University

Wetting states and processes attract plenty of interest of scientific and industrial societies. Air entrainment, i.e.,wetting failure, on smooth plate in wetting process has been investigated carefully before. Liquid bath entries of "rough"silicon wafers are studied experimentally in the present work, and the air entrainment condition is analyzed specially with the lubrication theory. The roughness effects on the moving contact lines are therefore explored. The contact line pinning is found to be the main reason for the dynamically enhanced hydrophobicity of rough surface, which implies an effective microscopic contact angle of θ_e = θ_Y + 90° where θY is the Young's contact angle of the material. Our results suggest that the solid surfaces can be considered as hydrophobic ones for a wide range of dynamic process, since they are normally rough. The work can also be considered as a starting point for investigating the high-speed advancing of moving contact line on rough surfaces.

关键词： wetting failure roughness lubrication theory contact angle

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Magneto‑Dielectric Synergy and Multiscale Hierarchical Structure Design Enable Flexible Multipurpose Microwave Absorption and Infrared Stealth Compatibility

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Nano-Micro Letters 2025年第2期17卷 401-416页

作者： chen Li Leilei Liang Baoshan Zhang Yi Yang Guangbin Ji School of Electronic Science and Engineering Nanjing UniversityNanjing 210093People’s Republic of China College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Developing advanced stealth devices to cope with radar-infrared(IR)fusion detection and diverse application scenarios is increasingly demanded,which faces significant challenges due to conflicting microwave and IR cloaking mechanisms and functional integration ***,we propose a multiscale hierarchical structure design,integrating wrinkled MXene IR shielding layer and flexible Fe_(3)O_(4)@C/PDMS microwave absorption *** top wrinkled MXene layer induces the intensive diffuse reflection effect,shielding IR radiation signals while allowing microwave to pass ***,the permeable microwaves are assimilated into the bottom Fe_(3)O_(4)@C/PDMS layer via strong magneto-electric *** theoretical and experimental optimization,the assembled stealth devices realize a near-perfect stealth capability in both X-band(8–12 GHz)and long-wave infrared(8–14μm)wavelength ***,it delivers a radar cross-section reduction of−20 dB m^(2),a large apparent temperature modulation range(ΔT=70℃),and a low average IR emissivity of ***,the optimal device demonstrates exceptional curved surface conformability,self-cleaning capability(contact angle≈129°),and abrasion resistance(recovery time≈5 s).This design strategy promotes the development of multispectral stealth technology and reinforces its applicability and durability in complex and hostile environments.

关键词： Microwave absorption Radar-infrared compatible stealth Wrinkled MXene Magneto-dielectric synergy Multifunction

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低估的自我——中等收入群体收入波动与主观阶层认同研究

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山西财经大学学报 2025年第1期47卷 1-15页

作者：陈涛峰杨希雷南开大学经济学院山东女子学院经济学院

中等收入群体作为社会的中坚力量，当其主观认同自身阶层时，能更有效地促进社会的经济发展与稳定。基于2010—2020年CFPS数据研究发现，我国中等收入群体存在明显的低位阶层认同现象，并且收入波动是导致这一现象产生的重要因素。机制... 详细信息

中等收入群体作为社会的中坚力量，当其主观认同自身阶层时，能更有效地促进社会的经济发展与稳定。基于2010—2020年CFPS数据研究发现，我国中等收入群体存在明显的低位阶层认同现象，并且收入波动是导致这一现象产生的重要因素。机制检验发现，收入波动通过改变中等收入群体对未来的预期、消费结构和对代际传递的担忧，影响其主观阶层认同感。调节效应分析显示，是否连续处于中等收入群体和家庭资产的数量是重要的调节变量。

关键词：中等收入群体收入波动主观阶层认同认同下移偏差低位认同未来预期消费结构代际传递

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Role of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective

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World Journal of Gastroenterology 2016年第33期22卷 7463-7477页

作者： Hui-Yi feng Yang-chao chen School of Biomedical Sciences Faculty of Medicinethe Chinese University of Hong Kong

The role of bile acids in colorectal cancer has been well documented,but their role in pancreatic cancer remains unclear. In this review,we examined the risk factors of pancreatic cancer. We found that bile acids are associated with most of these factors. Alcohol intake,smoking,and a high-fat diet all lead to high secretion of bile acids,and bile acid metabolic dysfunction is a causal factor of gallstones. An increase in secretion of bile acids,in addition to a long common channel,may result in bile acid reflux into the pancreatic duct and to the epithelial cells or acinar cells,from which pancreatic adenocarcinoma is derived. The final pathophysiological process is pancreatitis,which promotes dedifferentiation of acinar cells into progenitor duct-like cells. Interestingly,bile acids act as regulatory molecules in metabolism,affecting adipose tissue distribution,insulin sensitivity and triglyceride metabolism. As a result,bile acids are associated with three risk factors of pancreatic cancer: obesity,diabetes and hypertriglyceridemia. In the second part of this review,we summarize several studies showing that bile acids act as cancer promoters in gastrointestinal cancer. However,more question are raised than have been solved,and further oncological and physiological experiments are needed to confirm the role of bile acids in pancreatic cancer carcinogenesis.

关键词： Bile acids Pancreatic adenocarcinoma Pancreatitis Metabolic syndrome

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Low-temperature chlorination roasting technology for the simultaneous recovery of valuable metals from spent LiCoO_(2)cathode material

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 80-91页

作者： Junjie Shi Changle Hou Jingjing Dong Dong chen Jianzhong Li Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) Northeastern UniversityShenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China

With the continuous increase in the disposal volume of spent lithium-ion batteries(LIBs),properly recycling spent LIBs has become essential for the advancement of the circular *** study presents a systematic analysis of the chlorination roasting kinetics and proposes a new two-step chlorination roasting process that integrates thermodynamics for the recycling of LIB cathode *** activation energy for the chloride reaction was 88.41 kJ/mol according to thermogravimetric analysis–derivative thermogravimetry data obtained by using model-free,model-fitting,and Z(α)function(αis conversion rate).Results indicated that the reaction was dominated by the first-order(F1)model when the conversion rate was less than or equal to 0.5 and shifted to the second-order(F2)model when the conversion rate exceeded *** conditions were determined by thoroughly investigating the effects of roasting temperature,roasting time,and the mass ratio of NH_(4)Cl to LiCoO_(2).Under the optimal conditions,namely 400℃,20 min,and NH_(4)Cl/LiCoO_(2)mass ratio of 3:1,the leaching efficiency of Li and Co reached 99.43% and 99.05%,*** of the roasted products revealed that valuable metals in LiCoO_(2)transformed into CoCl_(2) and ***,the reaction mechanism was elucidated,providing insights for the establishment of a novel low-temperature chlorination roasting technology based on a crystal structure *** technology can guide the development of LIB recycling processes with low energy consumption,low secondary pollution,high recovery efficiency,and high added value.

关键词： spent lithium-ion battery thermodynamics chlorination roasting kinetics circular economy

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Degradation of ofloxacin using peroxymonosulfate activated by nitrogen-rich graphitized carbon microspheres:Structure and performance controllable study

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Journal of Environmental Sciences 2021年第1期33卷 10-20页

作者： Changsheng feng chen chen Yu Zhu Qi Cao chao chen Caiyun Jiang Yuping Wang School of Chemistry and Material Science Jiangsu Provincial Key Laboratory of Materials cycling and Pollution ControlNanjing Normal UniversityNanjing 210046China Department of Engineering and Technology Jiangsu lnstitute of CommerceNanjing 211168China

Nitrogen-rich graphitized carbon microspheres(NGCs)with hierarchically porous were constructed by *** different heat treatment conditions,the structure,morphology and properties of NGCs were studied by using multiple characterization *** results showed that the chemical microenvironments(*** chemistry,degree of graphitization and defective,etc.)and microstructures properties(***,specific surface area,particle size,etc.)could be delicately controlled via thermal carbonization *** degradation of ofloxacin(OFLX)by NGCs activated peroxymonosulfate(PMS)was studied *** was found that the synergistic coupling effect between optimum N or O bonding species configuration ratio(graphitic N and C=O)and special microstructure was the main reason for the enhanced catalytic activity of NGC-800(calcination temperature at 800°C).Electron paramagnetic resonance(EPR)experiments and radical quenching experiments indicated that the hydroxyl(·OH),sulfate(SO4^·-)and singlet oxygen(^1O_(2))were contributors in the NGC-800/PMS *** investigation of the durability of chemical structures and surface active sites revealed that undergo N bonding species configuration reconstruction and cannibalistic oxidation during PMS activation *** used NGC-800 physicochemical properties could be recovered by heat treatment to achieve the ideal catalytic *** findings proposed a valuable insight for catalytic performance and controllable design of construction.

关键词： Peroxymonosulfate Ofloxacin degradation Carbonization temperature Carbocatalyst

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