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Should atrial fibrillation patients with hypertension as an additional risk factor of the CHA2DS2-VASc score receive oral anticoagulation？

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Journal of Geriatric Cardiology 2018年第3期15卷 229-234页

作者： Juan WANG Da-Peng ZHANG Hong-Bin liu Jiu-chang ZHONG Xin-chun YANG Heart Center and Beijing Key Laboratory of Hypertension Beijing Chaoyang Hospital Affiliated to Capital Medical University Beijing China Department of Cardiology People's Liberation Army General Hospital Beijing China

Hypertension has been found to be increased a risk of stroke in atrial fibrillation （AF）. Both the European and U.S. guidelines advocate the use of the CHA2DSz-VASc （congestive heart failure, hypertension, age 〉 75 years, diabetes mellitus, stroke/transient ischemic attack, vascular disease, age 65-74 years, sex category） scheme for risk stratification. Although vitamin K antagonists is more effective than acetyl-salicylic acid at preventing ischaemic stroke, its benefit is offs by an increased haemorrhage risk. The risk of ischemic stroke in patients with AF and a CHA2DS2-VASc score of 1 are considered to be low risk and may be not expected to benefit from anticoagulation therapy. Hyper-tension carries an increased risk of ischemic stroke, however, it is also a clear risk factor for hemorrhage in AF. Therefore, the optimal anti-thrombotic management is highlighted in patients with AF with only one risk factor especially hypertension.

关键词： Atrial fibrillation Hypertension Stroke

Radiomics and molecular analysis:Bridging the gap for predicting hepatocellular carcinoma prognosis

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World Journal of Clinical Cases 2025年第4期13卷 56-60页

作者： chun-Han Cheng Wen-Rui Hao Tzu-Hurng Cheng Department of Medical Education Linkou Chang Gung Memorial HospitalTaoyuan 33305TaiwanChina Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561TaiwanChina Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002TaiwanChina Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404333TaiwanChina

This editorial examines a recent study that used radiomics based on computed tomography(CT)to predict the expression of the fibroblast-related gene enhancer of zeste homolog 2(EZH2)and its correlation with the survival of patients with hepatocellular carcinoma(HCC).By integrating radiomics with molecular analysis,the study presented a strategy for accurately predicting the expression of EZH2 from CT *** findings demonstrated a strong link between the radiomics model,EZH2 expression,and patient *** noninvasive approach provides valuable insights into the therapeutic management of HCC.

关键词： Hepatocellular carcinoma Computed tomography Radiomics Enhancer of zeste homologue 2 expression Non-invasive imaging

Simple digital PWM and PSM controlled DC-DC boost converter for luminance-regulated WLED driver

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The Journal of China Universities of Posts and Telecommunications 2009年第2期16卷 98-102页

作者： liu Xin GUO Shu-xu chang Yu-chun ZHU Shun-dong WANG Shuai State Key Laboratory on Integrated Optoelectronics College of Electronic Science and Engineering Jilin University Changchun 130012 China

This article presents a control strategy based on simple digital pulse-width modulation （DPWM） and pulse-skip modulation （PSM） for a DC-DC boost converter, to drive a luminance-regulated white light emitting diodes （WLEDs）. The presented control strategy not only retains most of the advantages and flexibilities of traditional digital PWM, but also reduces complexity and cost. Based on analyzing the principle of the presented control strategy, the white light emitting diode （WLED） driver is designed and simulated using the 0.6 μm CMOS process. Simulation results of the boost converter show that the power efficiency is above 76% for a full load, with a peak efficiency of 88% when supply voltage varies from 2.7 V to 5.5 V. The control strategy overcomes low efficiency for PWM mode with light load.

关键词： DC-DC boost converter DPWM PSM WLED

A comparison of ophthalmic education in China and America

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Annals of Eye Science 2017年第1期2卷 165-170页

作者： Ziyuan liu Mugen liu Robert chang Ping Huang chun Zhang Department of Ophthalmology Peking University Third HospitalPeking UniversityBeijing 100191China Department of Ophthalmology UT Southwestern Medical CenterTX 75209USA Stanford Byers Eye institute Palo AltoCA 94303USA Doheny Eye Institute UCLALos AngelesCA 90033USA

Training qualified ophthalmic professional is crucial for any eye care system *** of modern western Ophthalmology in China started late but develops *** review focused on ophthalmic education in China and US,describing details of the programs and analyzing the *** summary may provide useful information for practitioners of medical education from both countries and help improve the present training designs.

关键词： Ophthalmic education standardized ophthalmology residency training continuing medical education(CME)

Influence of Water Vapor on Silica Membrane： Adsorption Properties and Percolation Effect

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Chinese Journal of Chemical Physics 2015年第3期28卷 345-350,I0002页

作者： chun-lin Song Gang liu Faculty of Materials and Energy Southwest University Chongqing 400715 China Inorganic Membrane Group MESA+ Institute for Nanotechnology Faculty of Science and Technology University of Twente P.O. Box 217 7500 AE Enschede the Netherlands

The influence of water vapor on silica membrane with pore size of ,-4A has been investigated in terms of adsorption properties and percolation effect at 50 and 90 ℃. Two methods are employed： spectroscopic ellipsometry for water vapor adsorption and gas permeation of binary mixture of helium and H2O The adsorption behaviors on the silica membrane comply with the first-order Langmuir isotherm. The investigation demonstrates that helium flux through the silica membrane decreases dramatically in presence of H20 molecules. The transport of gas molecules through such small pores is believed not to be continuous any more, whereas it is reasonably assumed that the gas molecules hop from one occupied site to another unoccupied one under the potential gradient. When the coverage of H20 molecules on the silica surface increases, the dramatic decrease of helium flux could be related to percolation effect, where the adsorbed H20 molecules on the silica surface block the hopping of helium molecules.

关键词： Silica membrane Percolation effect Adsorption

Phase Transitions in Neutron Stars Within Modified Quark-Meson Coupling Model

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Communications in Theoretical Physics 2008年第7期50卷 180-186页

作者： MA chang-Qun GAO chun-Yuan School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking University Beijing 100871 China

K^- condensation and quark deconfinement phase transitions in neutron stars are investigated. We use the modified quark-meson coupling model for hadronic phase and the MIT bag model for quark phase. With the equation of state （EOS） solved self-consistently, we discuss the properties of neutron stars. We find that the EOS of pure hadron matter with condensed K- phase should be ruled out by the redshift for star EX00748-676, while EOS containing unpaired quark matter phase with B1/4 being about 180 MeV could be consistent with both this observation and the best measured mass of star PSR 1913 ＋ 16. But if the recent inferred massive star among Terzan 5 with M 〉 1.68M is confirmed, all the present EOSes with condensed phase and deconfined phase would be ruled out.

关键词： neutron star modified quark-meson coupling model nuclear matter quark matter

Overview of Computational Modeling in Nano/Micro Scaled Thin Films Mechanical Properties and Its Applications

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Computer Modeling in Engineering & Sciences 2019年第8期120卷 239-260页

作者： chang-chun Lee Pei-Chen Huang Department of Power Mechanical Engineering National Tsing Hua UniversityNo.101Section 2Kuang-Fu RoadHsinchu 30013Taiwan

This research reviews the application of computational mechanics on the properties of nano/micro scaled thin films,in which the application of different computational methods is *** concept and fundamental theories of concerned applications,material behavior estimations,interfacial delamination behavior,strain engineering,and multilevel modeling are thoroughly ***,an example of an interfacial adhesion estimation is presented to systematically estimate the related mechanical reliability issue in the microelectronic *** presented results show that the peeled mode fracture is the dominant delamination behavior of layered material system,with high stiffness along the bonding ***,the shear mode fracture being dominated as the polymer cover plate with low moduli is *** occurrence of crack advance is also significantly influenced by the interfacial crack length and applied ***,this paper could serve as a guideline of several engineering cases with the assistance of computational mechanics.

关键词： Computational mechanics mechanical responses nano/micro thin films

Classification and Reduction of Generalized Thin Film Equations

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Communications in Theoretical Physics 2009年第9期52卷 403-410页

作者： ZHU chun-Rong QU chang-Zheng Center for Nonlinear Studies Northwest University Xi＇an 710069 China College of Mathematics and Computer Science Anhui Normal University Wuhu 241000 China Department of Mathematics Northwest University Xi＇an 710069 China

Classification and reduction of the generalized fourth-order nonlinear differential equations arising from theliquid films are *** is shown that these equations have solutions on subspaces of the polynomial,exponential ortrigonometric form defined by linear nth-order ordinary differential equations with constant coefficients for n=4,...,*** examples of exact solutions are presented.

关键词： thin film equation classification invariant subspaces exact solutions

Patterns and determinants of plant richness by elevation in a mountain ecosystem in South Korea: area, mid-domain effect,climate and productivity

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Journal of Forestry Research 2015年第4期26卷 905-917页

作者： chang-Bae Lee Jung-Hwa chun Korea Green Promotion Agency 121 DunsanbukroSeoguDaejeon 302-831Republic of Korea Division of Forest Ecology Korea Forest Research Institute57 HoegiroDongdaemunguSeoul 130-712Republic of Korea

We examined patterns of plant species richness on an elevation gradient and evaluated the effects of cli- matic variables including mean annual temperature and precipitation, area, the mid-domain effect and productivity on species richness along two transects on Mt. Seorak, South Korea. A total of 235 plant species of 72 families and 161 genera were recorded from 130 plots along the two transects. Two different patterns, monotonic decline and a unimodal shape, were observed for woody plants with the change in elevation along the two transects, whereas multimodal patterns were observed for all plant species considered together and for herbaceous plants. Area and productivity showed significant relationships with total plant richness. Climatic variables were better predictors than other variables for variation by elevation in woody plant richness, whereas productivity was a more important variable for herbaceous plant richness. Although area was an important variable for predicting species richness pat- terns, the effects differed by transect and plant group. No empirical evidence was linked to the mid-domain *** elevational patterns may characterize different groups in the same taxon and there might be fundamental differences in the mechanisms underlying these richness patterns.

关键词： Area Climatic variables Elevationalpatterns Plant richness Productivity