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Tailoring Classical Conditioning Behavior in TiO_(2) Nanowires:ZnO QDs-Based Optoelectronic Memristors for Neuromorphic Hardware

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Nano-Micro Letters 2024年第7期16卷 265-280页

作者： Wenxiao Wang Yaqi Wang Feifei Yin Hongsen Niu Young-Kee shin Yang Li Eun-Seong Kim nam-Young Kim School of Information Science and Engineering University of JinanJinan 250022People’s Republic of China RFIC Centre NDAC CentreKwangwoon UniversityNowon-guSeoul 139-701South Korea Department of Electronics Engineering Kwangwoon UniversityNowon-GuSeoul 139-701South Korea School of Microelectronics Shandong UniversityJinan 250101People’s Republic of China Department of Molecular Medicine and Biopharmaceutical Sciences Seoul National UniversitySeoul 08826South Korea

Neuromorphic hardware equipped with associative learn-ing capabilities presents fascinating applications in the next generation of artificial ***,research into synaptic devices exhibiting complex associative learning behaviors is still ***,an optoelec-tronic memristor based on Ag/TiO_(2) Nanowires:ZnO Quantum dots/FTO was proposed and constructed to emulate the biological associative learning *** implementation of synaptic behaviors,including long and short-term plasticity,and learning-forgetting-relearning behaviors,were achieved in the device through the application of light and electrical *** the optoelectronic co-modulated characteristics,a simulation of neuromorphic computing was conducted,resulting in a handwriting digit recognition accuracy of 88.9%.Furthermore,a 3×7 memristor array was constructed,confirming its application in artificial visual *** importantly,complex biological associative learning behaviors were emulated by mapping the light and electrical stimuli into conditioned and unconditioned stimuli,*** training through associative pairs,reflexes could be triggered solely using light ***-sively,under specific optoelectronic signal applications,the four features of classical conditioning,namely acquisition,extinction,recovery,and generalization,were elegantly *** work provides an optoelectronic memristor with associative behavior capabilities,offering a pathway for advancing brain-machine interfaces,autonomous robots,and machine self-learning in the future.

关键词： Artificial intelligence Classical conditioning Neuromorphic computing Artificial visual memory Optoelectronic memristors ZnO Quantum dots

Advances in advanced solution-synthesis-based structural materials for tactile sensors and their intelligent applications

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InfoMat 2024年第1期6卷 31-64页

作者： Hongsen Niu Ning Li Eun-Seoung Kim Young Kee shin nam-Young Kim Guozhen Shen Yang Li School of Information Science and Engineering University of JinanJinanthe People's Republic of China RFIC Centre Department of Electronics EngineeringKwangwoon UniversitySeoulRepublic of Korea Department of Molecular Medicine and Biopharmaceutical Sciences Seoul National UniversitySeoulRepublic of Korea School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijingthe People's Republic of China School of Microelectronics Shandong UniversityJinanthe People's Republic of China

Intelligent applications,with tactile sensors at their core,represent significant advancement in the field of artificial ***,achieving perception abilities in tactile sensors that match or exceed human skin remains a formidable ***,the design and implementation of hierarchical structural materials are considered the optimal solution to this *** contrast to conventional methods,such as complicated lithography and three-dimensional printing,the cost-effective and scalable nature of advanced solution-synthesis methods makes them ideal for preparing diverse tactile sensors with hierarchical structural ***,the process and applicability of advanced solution synthesis methods have yet to form a seamless ***,the development and intellectualization of tactile sensors based on advanced solution synthesis methods are still in their early stages,and require a comprehensive and systematic review to usher in *** study delves into the advantages and disadvantages of various advanced solution synthesis methods,providing detailed ***,the positive effects of hierarchical structural materials constructed using these methods in tactile sensors and their intelligent applications are also discussed in ***,the challenges and future opportunities faced by this emerging field are summarized.

关键词： aqueous phase reduction artificial intelligence hydrothermal growth in situ polymerization tactile sensor

Methane Emission from Rice Fields:Necessity for Molecular Approach for Mitigation

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Rice science 2024年第2期31卷 159-178页

作者： Sujeevan RAJENDRAN Hyeonseo PARK Jiyoung KIM Soon Ju PARK Dongjin shin Jong-Hee LEE Young Hun SONG nam-Chon PAEK Chul Min KIM Department of Horticulture Industry Wonkwang UniversityIksan 54538Korea Plant Molecular Biology and Biotechnology Research Center Gyeongsang National UniversityJinju 52828Korea Department of Southern Area Crop Science National Institute of Crop ScienceMiryang 50424Korea Department of Agricultural Biotechnology Seoul National UniversitySeoul 08826Korea Department of Plant Science Plant Genomics and Breeding InstituteResearch Institute of Agriculture and Life SciencesSeoul National UniversitySeoul 08826Korea

Anthropogenic methane emissions are a leading cause of the increase in global averagetemperatures,often referred to as global *** soils play a significant role in methaneproduction,where the anaerobic conditions promote the production of methane by *** fields contribute a considerable portion of agricultural methane emissions,as riceplants provide both factors that enhance and limit methane *** plants harbor both methaneproducingand methane-oxidizing *** from rice roots provide source for methaneproduction,while oxygen delivered from the root aerenchyma enhances methane *** haveshown that the diversity of these microorganisms depends on rice cultivars with some genes characterizedas harboring specific groups of microorganisms related to methane ***,there is still aneed for research to determine the balance between methane production and oxidation,as rice plantspossess the ability to regulate net methane *** agronomical practices,such as fertilizerand water management,have been employed to mitigate methane ***,studiescorrelating agronomic and chemical management of methane with productivity are ***,evidences for breeding low-methane-emitting rice varieties are scattered largely due to the absence ofcoordinated breeding *** has indicated that phenotypic characteristics,such as rootbiomass,shoot architecture,and aerenchyma,are highly correlated with methane *** reviewdiscusses available studies that involve the correlation between plant characteristics and *** emphasizes the necessity and importance of breeding low-methane-emitting rice varieties inaddition to existing agronomic,biological,and chemical *** review also delves into the idealphenotypic and physiological characteristics of low-methane-emitting rice and potential breeding techniques,drawing from studies conducted

关键词： methane emission rice breeding aerenchyma greenhouse gas radial oxygen loss

Incidental renal cell carcinoma post bilateral nephrectomy in autosomal dominant polycystic kidney disease

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World Journal of Clinical Cases 2024年第28期12卷 6187-6194页

作者： Min-Ho shin nam-Kyu Choi Division of General Surgery Department of Hepato-Bilio-Pancreatic Surgery and Transplantation SurgeryChosun University College of MedicineGwangju 61453South Korea

BACKGROUND Renal cell carcinoma(RCC)is more common in patients with autosomal dominant polycystic kidney disease(ADPKD)than in the general *** RCC in ADPKD is challenging due to the presence of multiple renal cysts,often leading to delays and difficulties in distinguishing RCC from cyst infection or hemorrhage.A total of 38 kidneys were excised from 19 patients,with a mean age of 56.8 years and an average hemodialysis duration of 84.2 *** patients underwent open nephrectomies,and 11 underwent hand-assisted laparoscopic *** was detected in 15.8%of kidneys,affecting 21.1%of *** patients had multifocal RCC in both *** RCC cases were pT1 stage,with the largest lesion averaging 16.5 mm in *** average operative duration was 120 minutes,with intraoperative blood loss averaging 184.2 *** patients required blood *** complications occurred in five patients,with a mean hospital stay of 17.1 *** mean follow-up period was 28.1 *** The prevalence of RCC is higher in patients with ADPKD with ESRD than in those with ESRD ***,clinicians should be cautious and implement surveillance programs to monitor the development of RCC in patients with ADPKD,particularly those on dialysis.

关键词： Renal cell carcinoma Autosomal dominant polycystic kidney disease End-stage renal disease Kidney transplantation Nephrectomy

The SARS-CoV-2 spike protein induces lung cancer migration and invasion in a TLR2-dependent manner

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Cancer Communications 2024年第2期44卷 273-277页

作者： Mi-Jeong Kim Ji Young Kim Ji Hye shin Juhee Son Yeeun Kang Soo-Kyung Jeong Duk-Hwan Kim Kyun-Hwan Kim Eunyoung Chun Ki-Young Lee Department of Immunology Samsung Biomedical Research InstituteSungkyunkwan University School of MedicineSuwonRepublic of Korea Research and Development Center CHA Vaccine InstituteSeongnam-siRepublic of Korea Department of Molecular Cell Biology Sungkyunkwan University School of MedicineSuwonRepublic of Korea Department of Precision Medicine Sungkyunkwan University School of MedicineSuwonRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences&TechnologySamsung Medical CenterSungkyunkwan UniversitySeoulRepublic of Korea

Dear editor,Severe acute respiratory syndrome coronavirus2(SARS-CoV-2)infection can lead to severe outcomes in patients with cancer[1].It has been reported that patients with lung cancers disproportionately manifest severe COVID-19 with a high rate of hospitalization and death[2].Notably,the SARS-CoV-2 Spike(S)protein can induce hyper-inflammation in both epithelial cells and macrophages through toll-like receptor(TLR)1/TLR2 or TLR2/6-dependent nuclear factor-kappaB(NF-κB)path-way[3].However,molecular and cellular evidence on whether the SARS-CoV-2 virus affects the severity of lung cancer patients through TLR1/2 or TLR2/6 signaling remains unclear.

关键词： lung TLR2 invasion

Diagnosis of Middle Ear Diseases Based on Convolutional Neural Network

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Computer Systems Science & Engineering 2023年第8期46卷 1521-1532页

作者： Yunyoung nam Seong Jun Choi Jihwan shin Jinseok Lee Department of Computer Science and Engineering Soonchunhyang UniversityAsan31538Korea Department of Otolaryngology-Head and Nech Surgery Soonchunhyang University College of MedicineCheonan HospitalCheonan31151Korea Department of Biomedical Engineering Kyung Hee UniversityYonginKorea

An otoscope is traditionally used to examine the eardrum and ear canal.A diagnosis of otitis media(OM)relies on the experience of *** an examiner lacks experience,the examination may be difficult and *** paper presents an ear disease classification method using middle ear images based on a convolutional neural network(CNN).Especially the segmentation and classification networks are used to classify an otoscopic image into six classes:normal,acute otitis media(AOM),otitis media with effusion(OME),chronic otitis media(COM),congenital cholesteatoma(CC)and traumatic perforations(TMPs).The Mask R-CNN is utilized for the segmentation network to extract the region of interest(ROI)from otoscopic *** extracted ROIs are used as guiding features for the *** classification is based on transfer learning with an ensemble of two CNN classifiers:EfficientNetB0 and *** proposed model was trained with a 5-fold cross-validation *** proposed method was evaluated and achieved a classification accuracy of 97.29%.

关键词： Otitis media convolutional neural network acute otitis media otitis media with effusion chronic otitis media congenital cholesteatoma traumatic perforation Mask R-CNN

Facilitators of and barriers to emergency medical service use by acute ischemic stroke patients: A retrospective survey

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International Journal of Nursing Sciences 2017年第1期4卷 52-57页

作者： cha.nam shin Kyungeh An Jeongha Sim College of Nursing and Health Innovation Arizona State University500 N.Third St.PhoenixAZ 85004United States College of Nursing Virginia Commonwealth University1100 E.Leigh StRichmondVAUnited States Department of Nursing Jeonju University303 Cheonjam-roWansan-guJeonju560-759South Korea

Objective: The objective of the study was to identify facilitators and barriers to emergency medical service use among acute ischemic stroke patients in ***: This paper presents a secondary analysis of a retrospective survey that collected data from questionnaires and medical *** 233 acute ischemic stroke patients enrolled in a large-scale study,160 patients who had arrived at a hospital within 72 h after symptom onset were included in the data ***: Users of emergency medical services needed a shorter time than non-users to arrive at hospital (140 min vs.625 min.,p =0.001) and were more likely to arrive at hospital within 3 h of symptom onset (51.9% vs.31.5%,p =0.013).For those who first contacted emergency medical service,the facilitators of emergency medical service use were the presence of hemiparesis (p =0.003),bilateral paralysis (p =0.040),and loss of balance (p =0.021).The predominant barrier was the failure to recognize the urgency of symptoms (p 0.006).Conclusions: The use of emergency medical services reduced prehospital delay and increased the likelihood of patient arrival at hospital within 3 *** that experiencing typical stroke symptoms was a facilitator of emergency medical service use yet failure to recognize the urgency of symptoms was a barrier,public awareness should be raised as regards stroke symptoms and the benefits of using emergency medical services.

关键词： Barrier Emergency medical services Facilitator Social norms Stroke

Uterine rupture due to adenomyosis in an adolescent:A case report and review of literature

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World Journal of Clinical Cases 2023年第32期11卷 7888-7894页

作者： Nah Ihm Kim Ji shin Lee Jong Hee nam Department of Pathology Chonnam National University HospitalGwangju 61469South Korea Department of Pathology Chonnam National University Hwasun HospitalHwasun 58128South Korea Department of Pathology Chonnam National University Medical SchoolGwangju 61469South Korea

BACKGROUND Uterine rupture is a fatal medical complication with a high mortality *** cases of uterine rupture occur in late pregnancy or during labor and are mainly related to uterine scarring due to previous surgical *** is a possible risk factor for uterine ***,spontaneous uterine rupture due to severe adenomyosis in a non-gravida-teenaged female has not been reported in the literature to *** SUMMARY A 16-year-old girl was referred to our hospital for acute abdominal pain and hypovolemic shock with a blood pressure of 90/50 *** studies revealed a huge endometrial mass with multiple nodules in the lung,suggesting lung *** patient underwent an emergency total hysterectomy and wedge resection of the lung ***,the uterus showed diffuse adenomyosis with glandular and stromal *** nodules were endometrioma with massive *** demonstrated that the tumor cells were positive for PAX8,ER,and PR expression,leading to a final diagnosis of pulmonary endometriosis and uterine *** surgery,the patient remains in good condition without *** This is the first case of spontaneous uterine rupture due to adenomyosis in a nongravida adolescent.

关键词： Uterus Adenomyosis Malignancy Endometrioma Case report

Effects of electroacupuncture on the functionality of NG2-expressing cells in perilesional brain tissue of mice following ischemic stroke

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Neural Regeneration Research 2022年第7期17卷 1556-1565页

作者： Hong Ju Lee Da Hee Jung nam Kwen Kim Hwa Kyoung shin Byung Tae Choi Department of Korean Medical Science School of Korean MedicinePusan National UniversityYangsanRepublic of Korea Graduate Training Program of Korean Medicine for Healthy Aging Pusan National UniversityYangsanRepublic of Korea Department of Korean Ophthalmology Otolaryngology and DermatologySchool of Korean MedicinePusan National UniversityYangsanRepublic of Korea

Neural/glial antigen 2(NG2)-expressing cells has multipotent stem cell activity under cerebral *** study examined the effects of electroacupuncture(EA)therapy(2 Hz,1 or 3 mA,20 minutes)at the Sishencong acupoint on motor function after ischemic insult in the brain by investigating the rehabilitative potential of NG2-derived cells in a mouse model of ischemic *** stimulation alleviated motor deficits caused by ischemic stroke,and 1 mA EA stimulation was more efficacious than 3 mA EA stimulation or positive control treatment with edaravone,a free radical *** properties of NG2-expressing cells were altered with 1 mA EA stimulation,enhancing their survival in perilesional brain tissue via reduction of tumor necrosis factor alpha *** stimulation robustly activated signaling pathways related to proliferation and survival of NG2-expressing cells and increased the expression of neurotrophic factors such as brain-derived neurotrophic factor,tumor growth factor beta,and neurotrophin *** the perilesional striatum,EA stimulation greatly increased the number of NG2-expressing cells double-positive for oligodendrocyte,endothelial cell,and microglia/macrophage markers(CC1,CD31,and CD68).EA therapy also greatly activated brain-derived neurotrophic factor/tropomyosin receptor kinase B and glycogen synthase kinase 3 beta *** results indicate that EA therapy may prevent functional loss at the perilesional site by enhancing survival and differentiation of NG2-expressing cells via the activation of brain-derived neurotrophic factor-induced signaling,subsequently ameliorating motor *** animal experiments were approved by the Animal Ethics Committee of Pusan National University(approval ***2019-2199 and PNU2019-2884)on April 8,2019 and June 19,2019.

关键词： brain-derived neurotrophic factor differentiation electroacupuncture motor function neural/glial antigen 2 perilesional striatum stroke survival