Incidental renal cell carcinoma post bilateral nephrectomy in autosomal dominant polycystic kidney disease
作者机构：Division of General SurgeryDepartment of Hepato-Bilio-Pancreatic Surgery and Transplantation SurgeryChosun University College of MedicineGwangju 61453South Korea
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2024年第12卷第28期
页 面：6187-6194页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：The Research fund from the Chosun University Hospital No.2023-26
主 题：Renal cell carcinoma Autosomal dominant polycystic kidney disease End-stage renal disease Kidney transplantation Nephrectomy
摘 要：BACKGROUND Renal cell carcinoma(RCC)is more common in patients with autosomal dominant polycystic kidney disease(ADPKD)than in the general *** RCC in ADPKD is challenging due to the presence of multiple renal cysts,often leading to delays and difficulties in distinguishing RCC from cyst infection or hemorrhage.A total of 38 kidneys were excised from 19 patients,with a mean age of 56.8 years and an average hemodialysis duration of 84.2 *** patients underwent open nephrectomies,and 11 underwent hand-assisted laparoscopic *** was detected in 15.8%of kidneys,affecting 21.1%of *** patients had multifocal RCC in both *** RCC cases were pT1 stage,with the largest lesion averaging 16.5 mm in *** average operative duration was 120 minutes,with intraoperative blood loss averaging 184.2 *** patients required blood *** complications occurred in five patients,with a mean hospital stay of 17.1 *** mean follow-up period was 28.1 *** The prevalence of RCC is higher in patients with ADPKD with ESRD than in those with ESRD ***,clinicians should be cautious and implement surveillance programs to monitor the development of RCC in patients with ADPKD,particularly those on dialysis.
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