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Comprehensive analysis of clinical and biological value of Ing family genes in liver cancer

World Journal of Gastrointestinal Oncology 2024年第6期16卷 2592-2609页

作者： shi-Cai Liu School of Medical Information Wannan Medical CollegeWuhu 241002Anhui ProvinceChina

BACKGROUND Liver cancer(LIHC)is a malignant tumor that occurs in the liver and has a high mortality in *** Ing family genes were identified as tumor suppressor *** expression of these genes can lead to cell cycle arrest,senescence and/or *** family genes are promising targets for anticancer ***,their role in LIHC is still not well *** To have a better understanding of the important roles of Ing family members in *** A series of bioinformatics approaches(including gene expression analysis,genetic alteration analysis,survival analysis,immune infiltration analysis,prediction of upstream microRNAs(miRNAs)and long noncoding RNAs(lncRNAs)of Ing1,and Ing1-related gene functional enrichment analysis)was applied to study the expression profile,clinical relationship,prognostic significance and immune infiltration of Ing in *** relationship between Ing family genes expression and tumor associated immune checkpoints was investigated in *** molecular mechanism of Ing1 mediated hepatocarcinogenesis was preliminarily *** mRNA/protein expression of different Ing family genes in LIHC was analyzed in different databases,showing that Ing family genes were highly expressed in *** 47 samples from 366 LIHC patients,the Ing family genes were altered at a rate of 13%.By comprehensively analyzing the expression,clinical pathological parameters and prognostic value of Ing family genes,Ing1/5 was ***1/5 was related to poor prognosis of LIHC,suggesting that they may play key roles in LIHC tumorigenesis and *** of the target miRNAs of Ing1 was identified as *** upstream lncRNAs of hsa-miR-214-3p,U91328.1,and HCG17,were *** the same time,we found that the expression of Ing family genes was correlated with immune cell infiltration and immune checkpoint *** This study lays a foundation for further research on the potential mechanism and clinical v

关键词： Liver cancer Ing family genes Noncoding RNAs Immune cell infiltration Prognosis

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Statistical Process Monitoring Based on Ensemble Structure Analysis

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IEEE/CAA Journal of Automatica Sinica 2024年第8期11卷 1889-1891页

作者： Likang shi chudong Tong Ting Lan Xuhua shi Faculty of Electrical Engineering and Computer Science Ningbo UniversityNingbo 315211China

Dear Editor,This letter presents a novel process monitoring model based on ensemble structure analysis(ESA).The ESA model takes advantage of principal component analysis(PCA),locality preserving projections(LPP),and multi-manifold projections(MMP)models,and then combines the multiple solutions within an ensemble result through Bayesian *** the developed ESA model,different structure features of the given dataset are taken into account simultaneously,the suitability and reliability of the ESA-based monitoring model are then illustrated through ***:The requirement for ensuring safe operation and improving process efficiency has led to increased research activity in the field of process monitoring.

关键词： ensemble preserving letter

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Density peak clustering using tensor network

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Science china(Information Sciences) 2024年第3期67卷 321-322页

作者： Xiao shi Yun SHAng Institute of Mathematics Academy of Mathematics and Systems ScienceChinese Academy of Sciences School of Mathematical Sciences University of Chinese Academy of Sciences National Center for Mathematics and Interdisciplinary Sciences Key Laboratory of ManagementDecision and Information SystemsAcademy of Mathematics and Systems ScienceChinese Academy of Sciences

Tensor networks have been a powerful tool in simulating many-body physics and have recently gained recognition in the machine learning community due to their remarkable representation capabilities. However, using tens... 详细信息

关键词： Tensors

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砂布页轮柔性抛光表面微观形貌建模与预测

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西北工业大学学报 2024年第1期42卷 62-69页

作者：陈振赵盼闫蕊史诺史恺宁史耀耀西安航空学院机械工程学院陕西西安710077 西安明德理工学院智能制造与控制技术学院陕西西安710124 西北工业大学机电学院陕西西安710072

柔性抛光技术广泛应用于航空发动机整体叶盘叶片的精密加工。系统深入研究柔性抛光过程,了解抛光加工表面微观形貌生成的内涵,成为柔性抛光加工技术的重要研究内容之一。以砂布页轮为柔性磨具,通过空间几何坐标变换建立了砂布页轮表面... 详细信息

柔性抛光技术广泛应用于航空发动机整体叶盘叶片的精密加工。系统深入研究柔性抛光过程,了解抛光加工表面微观形貌生成的内涵,成为柔性抛光加工技术的重要研究内容之一。以砂布页轮为柔性磨具,通过空间几何坐标变换建立了砂布页轮表面磨粒的空间运动学模型及磨粒-工件几何学干涉模型,并研究了砂布页轮柔性变形对工件表面磨粒运动轨迹的影响。基于磨具表面形貌模型,利用MATLAB软件进行砂布页轮柔性抛光表面微观形貌生成过程仿真,并得到不同工艺参数下工件表面三维形貌及其影响规律,抛光实验结果验证了该仿真算法的正确性和有效性。

关键词：整体叶盘叶片柔性抛光空间几何坐标转换表面微观形貌

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Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and metaanalysis

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World Journal of Clinical Cases 2024年第1期12卷 107-118页

作者： shi-shi Wang Wang-Hao Liu Department of Emergency Medicine Huzhou Third Municipal HospitalThe Affiliated Hospital of Huzhou UniversityHuzhou 313000Zhejiang ProvinceChina Department of Geriatrics Huzhou Third Municipal Hospitalthe Affiliated Hospital of Huzhou UniversityHuzhou 313000Zhejiang ProvinceChina

BACKGROUND Frailty is a common condition in elderly patients who receive percutaneous coronary intervention(PCI).However,how frailty affects clinical outcomes in this group is *** To assess the link between frailty and the outcomes,such as in-hospital complic-ations,post-procedural complications,and mortality,in elderly patients *** The PubMed/MEDLINE,EMBASE,Cochrane Library,and Web of Science databases were screened for publications up to August *** primary outcomes assessed were in-hospital and all-cause mortality,major adverse cardiovascular events(MACEs),and major *** Newcastle-Ottawa Scale was used for quality *** Twenty-one studies with 739693 elderly patients undergoing PCI were *** was consistently associated with adverse *** patients had significantly higher risks of in-hospital mortality[risk ratio:3.45,95%confidence interval(95%CI):1.90-6.25],all-cause mortality[hazard ratio(HR):2.08,95%CI:1.78-2.43],MACEs(HR:2.92,95%CI:1.85-4.60),and major bleeding(HR:4.60,95%CI:2.89-7.32)compared to non-frail *** Frailty is a pivotal determinant in the prediction of risk of mortality,development of MACEs,and major bleeding in elderly individuals undergoing percutaneous coronary intervention.

关键词： Frailty Elderly Percutaneous coronary intervention Systematic review Meta-analysis

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Microstructural characterization and mechanical properties of(TiC+TiB)/TA15 composites prepared by an in-situ synthesis method

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china Foundry 2024年第2期21卷 168-174页

作者： Zhi-yong Zhang Jiao-jiao ch.ng Jia-qi Xie shi-bing Liu Kun shi Jun Zhao Shenyang Research Institute of Foundry Co. Ltd.CAMShenyang 110022China National Key Laboratory of Advanced Casting Technologies Shenyang 110022China

Titanium matrix composites reinforced with ceramic particles are considered a promising engineering material due to their combination of high specific strength,low density,and high *** this study,the TA15-based composites reinforced with a volume fraction of 10% to 25%(TiB+TiC)were prepared using powder metallurgy and casting *** characterization and phase constitution were examined using optical microscopy(OM),scanning electron microscopy(SEM),and X-ray diffraction(XRD).In addition,the microhardness,room temperature(RT)and high temperature(HT)tensile properties of the composites were *** revealed that the reinforcements are distributed uniformly even in the composites with a high volume of TiB and ***,as the volume fraction exceeds 15%,TiB and TiC particles become coarsening and exhibit rod-like and dendritic-like *** increases gradually from 321.2 HV for the base alloy to a maximum of 473.3 HV as the reinforcement increases to 25vol.%.Tensile test results indicate that a reinforcement volume fraction above 20% is beneficial for enhancing tensile strength and yield strength at high temperatures,but it has an adverse effect on room temperature ***,if the reinforcement volume fraction is below 20%,it can improve high-temperature elongation when the temperature exceeds 600℃.

关键词： titanium matrix composites microstucture microhardness tensile properties in-situ synthesis

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Novel milestones for early esophageal carcinoma:From bench to bed

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1104-1118页

作者： Ji-Han Qi shi-Ling Huang shi-Zhu Jin Department of Gastroenterology and Hepatology The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150086Heilongjiang ProvinceChina

Esophageal cancer(EC)is the seventh most common cancer worldwide,and esophageal squamous cell carcinoma(ESCC)accounts for the majority of cases of *** effectively diagnose and treat ESCC and improve patient prognosis,timely diagnosis in the initial phase of the illness is *** article offers a detailed summary of the latest advancements and emerging technologies in the timely identification of *** biology and epigenetics approaches involve the use of molecular mechanisms combined with fluorescence quanti-tative polymerase chain reaction(qPCR),high-throughput sequencing technology(next-generation sequencing),and digital PCR technology to study endogenous or exogenous biomolecular ch.nges in the human body and provide a decision-making basis for the diagnosis,treatment,and prognosis of *** invest-igation of the microbiome is a swiftly progressing area in human cancer research,and microorganisms with complex functions are potential components of the tumor *** intratumoral microbiota was also found to be connected to tumor *** application of endoscopy as a crucial technique for the early identification of ESCC has been essential,and with ongoing advancements in technology,endoscopy has continuously *** the advancement of artificial intelligence(AI)technology,the utilization of AI in the detection of gastrointestinal tumors has become increasingly *** implementation of AI can effectively resolve the discrepancies among observers,improve the detection rate,assist in predicting the depth of invasion and differentiation status,guide the pericancerous margins,and aid in a more accurate diagnosis of ESCC.

关键词： Early esophageal squamous cell carcinoma Epidemiology and risk factors Molecular biology Epigenetic Microbiology Endoscopy and artificial intelligence

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Cloud-Edge Collaborative Federated GAN Based Data Processing for IoT-Empowered Multi-Flow Integrated Energy Aggregation Dispatch

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Computers, Materials & Continua 2024年第7期80卷 973-994页

作者： Zhan shi Electric Power Dispatch.ng Control Center Guangdong Power Grid Co.Ltd.Guangzhou510030China

The convergence of Internet of Things(IoT),5G,and cloud collaboration offers tailored solutions to the rigorous demands of multi-flow integrated energy aggregation dispatch data *** generative adversarial networks(GANs)are instrumental in resource scheduling,their application in this domain is impeded by challenges such as convergence speed,inferior optimality search.ng capability,and the inability to learn from failed decision making ***,a cloud-edge collaborative federated GAN-based communication and computing resource scheduling algorithm with long-term constraint violation sensitiveness is proposed to address these *** proposed algorithm facilitates real-time,energy-efficient data processing by optimizing transmission power control,data migration,and computing resource *** employs federated learning for global parameter aggregation to enhance GAN parameter updating and dynamically adjusts GAN learning rates and global aggregation weights based on energy consumption constraint *** results indicate that the proposed algorithm effectively reduces data processing latency,energy consumption,and convergence time.

关键词： IoT federated learning generative adversarial network data processing multi-flowintegration energy aggregation dispatch

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Control of highly pathogenic avian influenza through vaccination

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Journal of Integrative Agriculture 2024年第5期23卷 1447-1453页

作者： Xianying Zeng Jianzhong shi Hualan chen State Key Laboratory for Animal Disease Control and Prevention Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin150069China

The stamping-out strategy has been used to control highly pathogenic avian influenza viruses in many countries,driven by the belief that vaccination would not be successful against such viruses and fears that avian influenza virus in vaccinated birds would evolve more rapidly and pose a greater risk to *** this review,we summarize the successes in controlling highly pathogenic avian influenza in china and make suggestions regarding the requirements for vaccine selection and *** addition,we present evidence that vaccination of poultry not only eliminates human infection with avian influenza virus,but also significantly reduces and abolishes some harmful characteristics of avian influenza virus.

关键词： avian influenza control highly pathogenic vaccination

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Cooperative control for heterogeneous multi-agent systems: progress, applications, and challenges

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Science china(Information Sciences) 2024年第5期67卷 318-320页

作者： Bing YAN Peng shi Jonathon chAMBERS School of Electrical and Mechanical Engineering Faculty of Science Engineering and TechnologyThe University of Adelaide School of Engineering College of Science and Engineering University of Leicester

Cooperative control for heterogeneous multi-agent systems(MASs) is a critical and rapidly evolving field in modern automation and robotics. characterized by the integration of agents with diverse capabilities and func... 详细信息

关键词： Multi agent systems

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