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Maternal cigarette smoking during pregnancy and reproductive health in children： a review of epidemiological studies

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Asian Journal of Andrology 2014年第1期16卷 39-49页

作者： Linn Berger Hfikonsen Andreas Ernst cecilia Host Ramlau-Hansen Department of Public Health Section for Epidemiology Aarhus University Aarhus Denmark

Maternal cigarette smoking may affect the intrauterine hormonal environment during pregnancy and this early fetal exposure may have detrimental effects on the future trajectory of reproductive health. In this review, we discuss the epidemiological literature on the association between prenatal exposure to maternal cigarette smoking and several aspects of reproductive health. The literature points towards an increased risk of the urogenital malformation cryptorchidism, but a potential protective effect on the risk of hypospadias in sons following prenatal cigarette smoking exposure. Studies on sexual maturation find a tendency towards accelerated pubertal development in exposed boys and girls. In adult life, prenatally exposed men have impaired semen quality compared with unexposed individuals, but an influence on fecundability, that is, the biological ability to reproduce, is less evident. We found no evidence to support an association between prenatal cigarette smoking exposure and testicular cancer. Among adult daughters, research is sparse and inconsistent, but exposure to cigarette smoking in utero may decrease fecundability. In conclusion, prenatal exposure to cigarette smoking may cause some long-term adverse effects on the reproductive health.

关键词： fertility prenatal exposure puberty testicular neoplasms time-to-pregnancy

The influence of bacteria on multitrophic interactions among plants, psyllids, and pathogen

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Insect Science 2017年第6期24卷 961-974页

作者： cecilia Tamborindeguy Ordom Brian Huot Freddy Ibanez Julien Levy Department of Entomology Texas A&M University College Station Texas USA Department of Horticultural Sciences Texas A&M University College Station Texas USA

The recent emergence ofseveralplant diseases caused by psyllid-borne bacterial pathogens worldwide （Candidatus Liberibaeter spp.） has created renewed interest on the interaction between psyllids and bacteria. In spite of these efforts to understand psyllid association with bacteria, many aspects of their interactions remain poorly understood. As more organisms are studied, subtleties on the molecular interactions as well as on the effects of the bacteria on the psyllid host are being uncovered. Additionally, psyllid-borne bacterial phytopathogens can also affect the host plant, which in turn can impact psyllid physiology and behavior. Here, we review the current literature on different aspects of the influence of bacteria on multitrophic interactions among plants, psyllids, and pathogens. We then highlight gaps that need to be addressed to advance this field, which can have significant implications for controlling these newly emergent and other plant diseases.

关键词： bacteria interaction Liberibacter microbiome phytoplasma psyllid

Non-breeding movements of the Black-tailed Gull(Larus crassirostris)

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Avian Research 2023年第2期14卷 206-214页

作者： Huan Xia cecilia Nilsson Kasper Thorup Chenxi Jia Fumin Lei Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing100101China College of Life Science University of Chinese Academy of SciencesBeijing100049China Center for Macroecology Evolution and ClimateGlobe InstituteUniversity of CopenhagenDK-2100CopenhagenDenmark Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunming650223China

With the continued development of tracking technology and increasing interest in animal movement,our understanding of migration behavior has become more ***,there are still many species that have not been well studied,particularly sea ***,we present the first year-round Global Positioning System(GPS)tracking data of the Black-tailed Gull(Larus crassirostris)at the population *** used solar-powered GPS-Global System for Mobile communication(GSM)loggers to successfully track 30 individuals breeding at Xingrentuo Islet,Liaoning Province,China,for 1-3 *** for one individual who roamed in the far north of the Yellow Sea during non-breeding period,all others did a directed southward *** routes and wintering sites differed among migrating gulls and between years for the birds tracked for two or more ***,during wintering,the migrating gulls were more likely to travel over a large body of water and shift sites,and some trajectories were quite complex,which was probably closely related to what we observed in the field about their boat-chasing *** to wintering movements,the post-breeding movements ranged over a smaller ***,almost all of them had a long post-breeding period near the breeding islet(≥120days,<220 km from the breeding islet),and 80%of the gulls who were tracked more than one year had at least one faithful post-breeding *** to the post-breeding period,only approximately half of the migrating gulls had a pre-breeding period that was shorter(3-20 days)and closer to the breeding islet(≤80 km).Migration distance varied among migrating gulls(range 209-2405 km)and the gulls moved least distance during postbreeding ***,we found that the southward movement of the migrating gulls occurred when the temperature near the breeding islet dropped;specifically,the gulls directly migrated southward away from the post-breeding *** results suggest that the B

关键词： Black-tailed Gull GPS tracking Larus crassirostris Migration Post-breeding Pre-breeding Sea bird Wintering

Turbocharging introgression breeding of perennial fruit crops:a case study on apple

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Horticulture Research 2020年第1期7卷 2040-2046页

作者： Satish Kumar Elena Hilario cecilia HDeng Claire Molloy The New Zealand Institute for Plant and Food Research Limited Hawkes Bay Research CentreHavelock NorthNew Zealand The New Zealand Institute for Plant and Food Research Limited Mount Albert Research CentreAucklandNew Zealand

The allelic diversity of primitive germplasm of fruit crops provides a useful resource for introgressing novel genes to meet consumer preferences and environmental ***-breeding facilitates the identification of novel genetic variation in the primitive germplasm and expedite its utilisation in cultivar breeding *** generations of pre-breeding could be required to minimise linkage drag from the donor parent and to maximise the genomic content of the recipient *** this study we investigated the potential of genomic selection(GS)as a tool for rapid background selection of parents for the successive generation.A diverse set of 274 accessions was genotyped using random-tag genotyping-by-sequencing,and phenotyped for eight fruit quality *** relationship between‘own phenotypes’of 274 accessions and their general combining ability(GCA)was also *** heritability influenced the strength of correspondence between own phenotype and the *** average(across eight traits)accuracy of predicting own phenotype was 0.70,and the correlations between genomic-predicted own phenotype and GCA were similar to the observed *** results suggest that genome-assisted parental selection(GAPS)is a credible alternative to phenotypic parental selection,so could help reduce the generation interval to allow faster accumulation of favourable alleles from donor and recipient parents.

关键词： breeding crops donor

A NETWORK ANALYSIS OF THE 2010 FIFA WORLD CUP CHAMPION TEAM PLAY

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Journal of Systems Science & Complexity 2013年第1期26卷 21-42页

作者： COTTA Carlos MORA Antonio M MERELO Juan Julin MERELO-MOLINA cecilia Department of Computer Science University of Mlaga Department of Architecture and Computer Technology University of Granada

This paper analyzes the network of passes among the players of the Spanish team during the last FIFA World Cup 2010,where they emerged as the champion,with the objective of explaining the results obtained from the behavior at the complex network *** team is considered a network with players as nodes and passes as(directed) edges.A temporal analysis of the resulting passes network is also done,looking at the number of passes,length of the chain of passes,and to network measures such as player centrality and clustering *** of the last three matches(the decisive ones) indicate that the clustering coefficient of the pass network remains high,indicating the elaborate style of the Spanish *** effectiveness of the opposing team in negating the Spanish game is reflected in the change of several network measures over time,most importantly in drops of the clustering coefficient and passing length/speed,as well as in their being able in removing the most talented players from the central positions of the ***'s ability to restore their combinative game and move the focus of the game to offensive positions and talented players is shown to tilt the balance in favor of the Spanish team.

关键词： Complex network complex systems FIFA World Cup football La Roja network analysis soccer Spanish team sports.

Speckle filtering of Synthetic Aperture Radar images using filters with object-size-adapted windows

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International Journal of Digital Earth 2018年第7期11卷 703-729页

作者： Sahel Mahdavi Bahram Salehi cecilia Moloney Weimin Huang Brian Brisco C-CORE Faculty of Engineering and Applied ScienceMemorial University of NewfoundlandSt John’sNLCanada Department of Electrical Engineering Faculty of Engineering and Applied ScienceMemorial University of NewfoundlandSt.John’sNLCanada Canada Center for Mapping and Earth Observation OttawaONCanada

Speckle degrades the radiometric quality of a Synthetic Aperture Radar(SAR)*** methods for speckle reduction have used a fixedsize window for filtering the entire ***,however,may not be effective for the entire image,as land covers of different sizes require different filtering *** this paper,a novel method is proposed by which each pixel in the image is filtered with a window appropriate for the size of object within *** real in-phase and the imaginary quadrature components of the SAR images determine the best window size and the pixels in the intensity image are filtered using their own optimal *** proposed method is presented for both singleand multi-polarized SAR images,and the results of several common filters that were modified are *** approach is applied to two RADARSAT-2 images:one over San Francisco,California,USA and the other over ***’s,Newfoundland and Labrador,Canada,producing results that were similar to,or outperformed,comparable filters while retaining details and suppressing speckle *** the method was successful for single-look intensity data,it offers great potential for multi-look and amplitude data as well.

关键词： Speckle Synthetic Aperture Radar(SAR) filters adaptive window size

Using Statistical Downscaling to Quantify the GCM-Related Uncertainty in Regional Climate Change Scenarios: A Case Study of Swedish Precipitation

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Advances in Atmospheric Sciences 2006年第1期23卷 54-60页

作者： Deliang CHEN Christine ACHBERGER Jouni R■IS■NEN cecilia HELLSTRM Earth Sciences Centre Gothenburg UniversityGothenburgSweden Laboratory for Climate Studies/National Climate CenterChina Meteorological AdministrationBeijingChina Earth Sciences Centre Gothenburg UniversityGothenburgSweden Department of Atmospheric Sciences University of HelsinkiFinland

There are a number of sources of uncertainty in regional climate change scenarios. When statistical downscaling is used to obtain regional climate change scenarios, the uncertainty may originate from the uncertainties in the global climate models used, the skill of the statistical model, and the forcing scenarios applied to the global climate model. The uncertainty associated with global climate models can be evaluated by examining the differences in the predictors and in the downscaled climate change scenarios based on a set of different global climate models. When standardized global climate model simulations such as the second phase of the Coupled Model Intercomparison Project （CMIP2） are used, the difference in the downscaled variables mainly reflects differences in the climate models and the natural variability in the simulated climates. It is proposed that the spread of the estimates can be taken as a measure of the uncertainty associated with global climate models. The proposed method is applied to the estimation of global-climate-model-related uncertainty in regional precipitation change scenarios in Sweden. Results from statistical downscaling based on 17 global climate models show that there is an overall increase in annual precipitation all over Sweden although a considerable spread of the changes in the precipitation exists. The general increase can be attributed to the increased large-scale precipitation and the enhanced westerly wind. The estimated uncertainty is nearly independent of region. However, there is a seasonal dependence. The estimates for winter show the highest level of confidence, while the estimates for summer show the least.

关键词： Statistical downscaling global climate model climate change scenario uncertainty

Life cycle assessment of urban uses of biochar and case study in Uppsala,Sweden

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Biochar 2022年第1期4卷 889-905页

作者： Elias S.Azzi Erik Karltun cecilia Sundberg Department of Sustainable Development Environmental Engineeringand Sciences(SEED)KTH Royal Institute of TechnologyTeknikrigen 10B11428 StockholmSweden Department of Soil and Environment Swedish University of Agricultural Sciences(SLU)UppsalaSweden Department of Energy and Technology Swedish University of Agricultural Sciences(SLU)UppsalaSweden

Biochar is a material derived from biomass pyrolysis that is used in urban *** environmental impacts of new biochar products have however not been ***,the life cycle assessments of 5 biochar products(tree planting,green roofs,landscaping soil,charcrete,and biofilm carrier)were performed for 7 biochar supply-chains in 2 energy *** biochar products were benchmarked against reference products and oxidative use of biochar for steel *** demand was then estimated,using dynamic material flow analysis,for a new city district in Uppsala,*** a decarbonised energy system and with high biochar stability,all biochar products showed better climate performance than the reference products,and most applications outperformed biomass use for decarbonising steel *** climate benefits of using biochar ranged from−1.4 to−0.11 tonne CO_(2)-eq tonne−1 biochar in a decarbonised energy *** other environmental impact categories,biochar products had either higher or lower impacts than the reference products,depending on biochar supply chain and material substituted,with trade-offs between sectors and impact ***,several use-phase effects of biochar were not included in the assessment due to knowledge *** Uppsala’s new district,estimated biochar demand was around 1700 m^(3)year^(−1)during the 25 years of *** 2100,23%of this biochar accumulated in landfill,raising questions about end-of-life management of biochar-containing ***,in a post-fossil economy,biochar can be a carbon dioxide removal technology with benefits,but biochar applications must be designed to maximise co-benefits.

关键词： Biochar Carbon dioxide removal Urban areas Bioeconomy Life cycle assessment Material flow analysis

Tumor-associated myeloid cells:diversity and therapeutic targeting

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Cellular & Molecular Immunology 2021年第3期18卷 566-578页

作者： Alberto Mantovani Federica Marchesi Sebastien Jaillon cecilia Garlanda Paola Allavena Department of Immunology and Inflammation Humanitas Clinical and Research Center-IRCCSRozzanoItaly Department of Biomedical Science Humanitas UniversityRozzanoItaly The William Harvey Research Institute Queen Mary University of LondonLondonUK Department of Biotechnology and Translational Medicine University of MilanMilanItaly

Myeloid cells in tumor tissues constitute a dynamic immune population characterized by a non-uniform phenotype and diverse functional *** tumor-associated macrophages(TAMs),which are more abundantly represented,and tumor-associated neutrophils(TANs)are known to sustain tumor cell growth and invasion,support neoangiogenesis and suppress anticancer adaptive immune *** recent decades,several therapeutic approaches have been implemented in preclinical cancer models to neutralize the tumor-promoting roles of both TAMs and *** of the most successful strategies have now reached the clinic and are being investigated in clinical *** this review,we provide an overview of the recent literature on the evergrowing complexity of the biology of TAMs and TANs and the development of the most promising approaches to target these populations therapeutically in cancer patients.

关键词： tumor-associated macrophages tumor microenvironment macrophage targeting