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Spatiotemporal patterns of burned areas,fire drivers,and fire probability across the equatorial Andes

Journal of Mountain Science 2021年第4期18卷 952-972页

作者： Xavier ZAPATA-RiOS carmen lopez-fabara Abigail NAVARRETE Sandra TORRES-PAGUAY Miguel FLORES Department of Civil and Environmental Engineering Escuela Politecnica NacionalLadron de Guevara E11-253P.O.Box 17-01-2759QuitoEcuador Center for Research and Water Resources Studies(CIERHI) Escuela Politecnica NacionalLadron de Guevara E11-253P.O.Box 17-01-2759QuitoEcuador Faculty of Agricultural Sciences Universidad Central del EcuadorAv.UniversitariaP.O.Box 17-03-100QuitoEcuador Modeling Optimization and Inferential Statistics Group(MODES)Department of MathematicsEscuela Politecnica NacionalLadron de Guevara Ell-253P.O.Box 17-01-2759QuitoEcuador

Field-based fire studies in the equatorial Andes indicate that fires are strongly associated with biophysical and anthropogenic ***,fire controls and fire regimes at the regional scale remain ***,this paper describes spatial and temporal burned-area patterns,identifies biophysical and anthropogenic fire drivers,and quantifies fire probability across 6°of latitude and 3°of longitude in the equatorial *** spatial and temporal burned-area analysis was carried out based on 18 years(2001-2018)of the MCD64 A1 MODIS burned-area ***,topography,vegetation,and anthropogenic variables were integrated in a logistic regression model to identify the significance of explanatory variables and determine fire occurrence probability.A total of 5779 fire events were registered during the 18 years of this study,located primarily along the western cordillera of the Andes and spreading from North to ***-eight percent of these fires took place within two fire hotspots located in the northwestern and southwestern corners of the study ***-nine percent occurred during the second part of the year,between June and *** largest density of fires was primarily located on herbaceous vegetation and *** show that mean monthly temperature,precipitation and NDVI during the prefire season,the location of land cover classes such as forest and agriculture,distance to roads and urban areas,slope,and aspect were the most important determinants of spatial and temporal fire *** logistic regression model achieved a good accuracy in predicting fire probability(80%).Probability was higher in the southwestern and northern corners of the study area,and lower towards the north in the western and eastern piedmonts of the *** analysis contributes to the understanding of fires in mountains within the *** results here presented have the potential to contribute to fire management and control in the regi

关键词： MODIS MCD64A1 Spectral vegetation indices Pre-fire season NDVI and precipitation Remote sensing

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Generation of lossy mode resonances(LMR)using perovskite nanofilms

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Opto-Electronic Advances 2024年第2期7卷 33-40页

作者： Dayron Armas Ignacio R.Matias M.carmen lopez-Gonzalez Carlos Ruiz Zamarreño Pablo Zubiate Ignacio del Villar Beatriz Romero Electrical Electronic and Communications Engineering DepartmentPublic University of NavarraPamplona 31006Spain Institute of Smart Cities(ISC) Public University of NavarraPamplona 31006Spain Experimental Science and Technology School Rey Juan Carlos UniversityMostoles 28933Spain

The results presented here show for the first time the experimental demonstration of the fabrication of lossy mode resonance(LMR) devices based on perovskite coatings deposited on planar waveguides. Perovskite thin films have been obtained by means of the spin coating technique and their presence was confirmed by ellipsometry, scanning electron microscopy, and X-ray diffraction testing. The LMRs can be generated in a wide wavelength range and the experimental results agree with the theoretical simulations. Overall, this study highlights the potential of perovskite thin films for the development of novel LMR-based devices that can be used for environmental monitoring, industrial sensing, and gas detection, among other applications.

关键词： perovskite thin films slab waveguide lossy mode resonance

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Multi-omic study to unmask genes involved in prostate cancer development in amulti-case family

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Cancer Communications 2024年第3期44卷 443-447页

作者： Lucia Chica-Redecillas Sergio Cuenca-lopez Eduardo Andres-Leon Laura carmen Terron-Camero Blanca Cano-Gutierrez Jose Manuel Cozar Jose Antonio Lorente Fernando Vazquez-Alonso Luis Javier Martinez-Gonzalez Maria Jesus Alvarez-Cubero GENYO Centre for Genomics and Oncological ResearchPfizerUniversity of GranadaAndalusian Regional GovernmentPTS GranadaGranadaGranadaSpain Department of Biochemistry Molecular Biology III and ImmunologyFaculty of MedicineUniversity of GranadaPTS GranadaGranadaGranadaSpain Bioinformatics Unit Institute of Parasitology and Biomedicine“López-Neyra”Spanish National Research CouncilGranadaGranadaSpain Nursery Service.University Hospital Clínico San Cecilio GranadaGranadaSpain Urology Department University Hospital Virgen de las NievesGranadaGranadaSpain Legal Medicine and Toxicology Department Faculty of MedicineUniversity of GranadaPTS GranadaGranadaGranadaSpain Ibs Biosanitary Research InstituteGranadaGranadaSpain

Dear Editor,Hereditary prostate cancer(PC)comprises 5%-10%of all PC *** increased risk of PC in menwith a family his-tory of the disease is well known and is commonly caused by germline mutations,leading to clinical guidelines men-tioning various genes for identifying high-risk ***,the complex inheritance patterns involvingmul-tiple single nucleotide polymorphisms(SNPs)make it a genetically heterogeneous disease,with genetic testing still in its early stages.

关键词： cancer clinical cases

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Dynamic assessment of variations in pupil diameter using swept‑source anterior segment optical coherence tomography after phakic collamer lens implantation

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Eye and Vision 2021年第6期8卷 396-403页

作者： Felix Gonzalez‑lopez carmen Bouza‑Miguens Victor Tejerina Vasyl Druchkiv Blas Mompean Julio Ortega‑Usobiaga Rafael Bilbao‑Calabuig Department of Refractive Surgery Clinica BavieraMelchor Fernández Almagro928029 MadridSpain Department of Research and Development Clinica BavieraValenciaSpain

Purpose:To dynamically assess variations in pupil diameter induced by changes in brightness in myopic eyes implanted with an implantable collamer lens(ICL,STAAR Surgical)with a central ***:This prospective,observational single-center case series study comprised 65 eyes from 65 consecutive patients undergoing ICL implant.A modified commercially available swept-source Fourier-domain anterior segment optical coherence tomography(AS-OCT)device was used for imaging and performing dynamic pupillometry under changing light conditions before and after a mean follow-up interval of four months after ***:Preoperative mean pupil size under photopic conditions was 3.38±0.64 mm;after surgery,this increased to 3.48±0.61 *** pupil size under scotopic light conditions was 5.72±0.79 mm before surgery and 5.84±0.77 mm *** differences between preoperative and postoperative pupil diameter in miosis and mydriasis were 0.10±0.44 mm(P=0.078)and 0.12±0.58 mm(P=0.098),*** scotopic pupil exceeded the optic zone of the implanted lens in 39 eyes(60%).The mean central vault value was 412±177μm under maximum miosis and 506±190μm under maximum *** found a positive correlation between vault and differences in pupil diameter under all light conditions(P<0.05).Conclusion:Dynamic AS-OCT enables a very precise determination of the pupillary diameter in the iris *** changes in the pupil diameter under different light conditions after the implantation of an ICL are related to the postoperative vault.

关键词： Phakic collamer lens ICL Pupil OCT Central hole Central port Posterior chamber phakic lens

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Evaluation of patient visual comfort and repeatability of refractive values in non-presbyopic healthy eyes

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International Journal of Ophthalmology(English edition) 2015年第5期8卷 1031-1036页

作者： Francisco Segura Ana Sanchez-Cano carmen lopez de la Fuente Lorena Fuentes-Broto Isabel Pinilla Department of Surgery Gynaecology and ObstetricsUniversity of Zaragoza Aragon Health Sciences Institute University of Zaragoza Department of Applied Physics University of Zaragoza Department of Physiology and Pharmacology University of Zaragoza Department of Ophthalmology Lozano Blesa University Hospital

AIMTo evaluate the intra-operator repeatability in healthy subjects using the WAM-5500 auto-kerato/refractometer and the iTrace aberrometer, to compare the refractive values and the subjective refraction obtained with both devices and to determine which of these three spherocylindrical corrections allows the subject to achieve the best visual ***-two non-presbyopic healthy eyes of 42 subjects were enrolled in this prospective study. Refractive values were compared, evaluating the repeatability, the relationship between the methods and the best visual comfort ***, cylinder and axis results showed good intraclass correlation coefficients (ICC); the highest ICC was obtained using the spherical refraction with the autorefractometer and the aberrometer, achieving levels of 0.999 and 0.998, respectively. The power vector (PV) was calculated for each refraction method, and the results indicated that there were no statistically significant differences between them (P>0.05). Direct comparison of PV measurements using the three methods showed that aberrometer refraction gave the highest values, followed by the subjective values; the autorefractometer gave the lowest values. The subjective method correction was most frequently chosen as the first selection. Equal values were found for the autorefractometer and the aberrometer as the second *** iTrace aberrometer and the WAM-5500 auto-kerato/refractometer showed high levels of repeatability in healthy eyes. Refractive corrections with the aberrometer, the autorefractometer and subjective methods presented similar results, but spherocylindrical subjective correction was the most frequently selected option. These technologies can be used as complements in refractive evaluation, but they should not replace subjective refraction.

关键词： repeatability optical correction aberrometer autorefractometer subjective refraction

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Effects of Perinatal Undernutrition and Massage Stimulation upon the Ambiguus Nucleus in the Rat Prior to Weaning

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Journal of Behavioral and Brain Science 2013年第2期3卷 200-209页

作者： Dora lopez-Jimenez carmen Torrero Mirelta Regalado Manuel Salas Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology National Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico Department of Developmental Neurobiology and Neurophysiology Institute of NeurobiologyNational Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico

Undernutrition produces morphological brain alterations and cognitive deficiencies in children of underdeveloped countries. The central nervous system (CNS) alterations mainly interfere with the anatomical organization of areas undergoing a phase of intense postnatal cell proliferation, disrupting plastic processes like learning, memory, and phonation. In the rat pup, prenatal malnutrition interferes with the elaboration of ultrasonic vocalizations (USVs) by poorly understood mechanisms. The neuronal caudal portion of the nucleus ambiguus (Ambc) innervates the laryngeal intrinsic muscles to produce phonation, a basic USV communication system. During postnatal development, enhanced plasticity phenomena play a fundamental role in improving brain function. Thus, the massage stimulation (MS) may accelerate growth and induce neurogenesis in different areas of the brain. The current study analyzed the effects of a daily 10-min MS on the dendritic tree and perikarya measurements of Ambc multipolar motoneurons (Golgi-Cox) of perinatally underfed (U), control (C), control massage-stimulated (CMS), and underfed massage-stimulated (UMS) groups at postnatal days (PDs) 8, 12, and 15. The data indicated that the dendritic scores were reduced (p < 0.05) in both number and density at PD8 and PD15 in the U subjects and that MS increased the values of these parameters (p < 0.05). In addition, MS induced body weight gain in both U and CMS groups, and it enhanced the dendritic density in CMS subjects. These results show that MS during the pre-weaning period restores the plastic properties of the Ambc over the hypoplastic multipolar motoneuron after the alterations caused by perinatal undernutrition.

关键词： Nucleus Ambiguus Development Massage Stimulation Perinatal Undernutrition Rat Pups

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Hydrometeorology of Anthropogenic Erosion in the Metropolitan Region of São Paulo

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Journal of Environmental Protection 2021年第12期12卷 1234-1253页

作者： Maria del carmen Sanz lopez Augusto José Pereira Filho Jorge Luiz Diaz Pinaya Departamento de Ciências Atmosférica do Instituto de Astronomia Geofísica e Ciências Atmosféricas da Universidade de S&atilde o Paulo S&atilde o Paulo Brazil

Erosive processes play an important role in environmental degradation. Rain is the main erosive agent in the Metropolitan Region of Sao Paulo. This study characterized the erosion events caused by precipitation leveraging the accumulated daily precipitation estimate generated by the Climate Prediction Center Morphing Method (CMORPH) and integrating the surface telemetric network using the Statistical Objective Analysis method (SOAS). From the Civil Defense database, 400 events were identified in the Metropolitan region of Sao Paulo (MRSP) area between 2000 and 2013 and, of these, 3 were chosen to carry out meteorological and climatological analyses. In an initial observation, 58% of them were found to occur in summer. Two regions with the highest number of erosion events were observed, in the Serra do Mar and Serra da Cantareira. In the Serra do Mar core, the municipality of São Bernardo do Campo was the one with the greatest amount of erosion. Precipitation volumes were estimated for accumulations of 30 minutes, 1 day, 1 month, and 1 year. The results, from the 3 events, indicate accumulated precipitation in 30 minutes from 10 mm to 19.8 mm, daily from 30.8 mm to 69.5 mm, and 1 month from 369.7 mm to 742.5 mm, and 1 year (2010) from 1712.9 mm to 1961.8 mm. In these events, it was noted that there were heavy rains in December 2009 and January 2010. It was also noted that the CMORPH and SOAS identify the rain events found by the São Paulo meteorological radar. The meteorological analyzes of the events based on images from the São Paulo meteorological radar and the Meteosat-9 satellite indicate that the active precipitation systems are associated with cold fronts, instability lines, and isolated convection.

关键词： Hydrometeorology Anthropogenic Erosion CMORPH SOAS

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Review of the El Soplao Amber Outcrop,Early Cretaceous of Cantabria,Spain

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Acta Geologica Sinica(English Edition) 2010年第4期84卷 959-976页

作者： María NAJARRO Enrique PENALVER Ricardo PEREZ-DE LA FUENTE Jaime ORTEGA-BLANCO Cesar MENOR-SALVAN Eduardo BARRON carmen SORIANO Idoia ROSALES Rafael lopez DEL VALLE Francisco VELASCO Fernando TORNOS Véronique DAVIERO-GOMEZ Bernard GOMEZ Xavier DELCLOS Instituto Geologico y Minero de Espana E-28003MadridSpain Departament d'Estratigrafia Paleontologia i Geociencies MarinesFacultat de GeologiaUniversitat de BarcelonaE-08071BarcelonaSpain Centro de Astrobiologia(CSIC-INTA) E-28850Torrejon de ArdozSpain European Synchrotron Radiation Facilities F-38000 GrenobleFrance/Geosciences Rennes-Universite de Rennes 1F-35042 RennesFrance El Soplao S.L. Prao El CollaoE-39553CantabriaSpain Universidad del Pais Vasco Dpto.Mineralogia y PetrologiaE-48080 BilbaoSpain CNRS-UMR 5125 PEPS Universite Lyon 1GeodeF-69622 VilleurbanneFrance

El Soplao outcrop, an Early Cretaceous amber deposit recently discovered in northern Spain （Cantabria）, has been shown to be the largest site of amber with arthropod inclusions that has been found in Spain so far. Relevant data provided herein for biogeochemistry of the amber, palynology, taphonomy and arthropod bioinclusions complement those previously published. This set of data suggests at least two botanical sources for the amber of El Soplao deposit. The first （type A amber） strongly supports a source related to Cheirolepidiaceae, and the second （type B amber） shows non-specific conifer biomarkers. Comparison of molecular composition of type A amber with Frenelopsis leaves （Cheirolepidiaceae） strongly suggests a biochemical affinity and a common botanical origin. A preliminary palynological study indicates a regional high taxonomical diversity, mainly of pteridophyte spores and gymnosperm pollen grains. According to the preliminary palynological data, the region was inhabited by conifer forests adapted to a dry season under a subtropical climate. The abundant charcoalified wood associated with the amber in the same beds is evidence of paleofires that most likely promoted both the resin production and an intensive erosion of the litter, and subsequent great accumulation of amber plus plant cuticles. In addition, for the first time in the fossil record, charcoalified plant fibers as bioinclnsions in amber are reported. Other relevant taphonomic data are the exceptional presence of serpulids and bryozoans on the surfaces of some amber pieces indicating both a long exposure on marine or brackish-water and a mixed assemblage of amber. Lastly, new findings of insect bioiuclusions, some of them uncommon in the fossil record or showing remarkable adaptations, are reported. In conclusion, a documented scenario for the origin of the El Soplao amber outcrop is provided.

关键词： fossil resin chemotaxonomy paleobotany charcoal arthropod bioinclusions taphonomy EarlyAlbian

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Heritage risk index:A multi-criteria decision-making tool to prioritize municipal historic preservation projects

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Frontiers of Architectural Research 2020年第2期9卷 403-418页

作者： Jonathan Ruiz-Jaramillo carmen Munoz-Gonzalez Maria Dolores Joyanes-Diaz Eduardo Jimenez-Morales Jose Manuel lopez-Osorio Roberto Barrios-Perez Carlos Rosa-Jimenez Department of Art and Architecture School of ArchitectureUniversidad de MalagaMalaga 29071Spain

The current pressure on the built historical heritage requires a global evaluation to develop strategies for its preservation.A combined vision of the state of conservation of architectural heritage is essential to highlight the vulnerabilities of the structure from which harmonized measures can be proposed for its *** study proposes a multi-criteria analysis methodology that considers a qualitative and quantitative approach to organize the global conservation state of heritage buildings hierarchically.A global index can be determined on the basis of the generation of an interoperable data matrix by defining a set of indicators to assess different components of a *** index describes the risk with respect to the stability,safety,and habitability of the *** methodology aims to achieve the state of the building in an integral way by obtaining a simple and objective index that enables efficient comparison among different *** application of this methodology to a historic area allows creating a hierarchical map of risk to stablish priorities for intervention and enable a sustainable and critical management and planning over the actions of maintenance,conservation,and *** this way,a holistic vision of the complex reality of built heritage and the urban landscape is obtained to identify critical areas of priority intervention.

关键词： Historic city State of conservation Risk index Intervention priority Architectural heritage

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Update on the treatment of metastatic renal cell carcinoma

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World Journal of Clinical Oncology 2022年第1期13卷 1-8页

作者： Rafael Antonio Medina lopez Ines Rivero Belenchon Javier Mazuecos-Quiros carmen Belen Congregado-Ruiz Felipe Counago Department of Urology and Nephrology Virgen del Rocio University HospitalBiomedical Institute of Seville/CSIC/University of SevilleSevilla 41013Spain Department of Urology and Nephrology Virgen del Rocio University HospitalSeville 41005Spain Radiation Oncology Hospital Universitario QuironsaludHospital La LuzUniversidad Europea de MadridMadrid 28223Spain

Metastatic renal cell cancer(mRCC)management has undergone a paradigm shift in recent *** first revolution came with the emergence of vascular endothelial growth factor inhibitors;there was a second wave with the unprecedented success of checkpoint inhibitors,and then the latest approach,which is becoming the new care standard in mRCC,of combining these two strategies in different *** results of Checkmate-214 after 42 mo of follow-up were consistent with previously published results showing the superiority of nivolumab/ipilimumab over sunitinib in progression free survival(PFS),overall survival(OS),and objective response rate(ORR)in intermediate and high-risk ***,several studies presented at the American Society of Clinical Oncology 2020 suggested that the best place,and so far,the only one for nivolumab/ipilimumab is the frontline *** update on Keynote-426 after 23 mo of follow-up showed no superiority of pembrolizumab/axitinib over sunitinib in favorable-risk mRCC,suggesting that it should no longer be the first line of choice in low-risk ***,the phase III Checkmate 9ER trial results revealed the superiority of nivolumab/cabozantinib vs sunitinib in PFS,OS,and ORR,providing a new first-line option among all International Metastatic RCC Database Consortium risk *** phase II clinical trials also presented this year showed promising results with new combination therapies such as nivolumab/sitravatinib,cabozantinib/atezolizumab,and lenvatinib/pembrolizumab,providing promising grounds upon which to start phase III *** addition,other works are using novel therapeutic agents with different mechanisms of action,including telaglenastat(a glutaminase inhibitor),entinostat[an inhibitor of histone deacetylases(HDACs)],and olaparib and talazoparib,poly(ADP-ribose)polymerase inhibitors widely used in other ***,some questions regarding mRCC management still need to be addressed,such as head-to-head co

关键词： Metastatic renal cell carcinoma Systemic treatment Immune checkpoint inhibitors Antiangiogenic Update Biomarkers

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