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Bacterial extracts and bioformulates as a promising control of fruit body rot and root rot in avocado cv. Hass

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Journal of Integrative Agriculture 2020年第3期19卷 748-758页

作者： David GRANADA Lorena LÓPez-LUJAN Sara RAMIRez-RESTREPO Juan MORALES carlos peláez-jaramillo Galdino ANDRADE Juan carlos BEDOYA-PERez Phytosanitary and Biological Control Unit Corporation for Biological ResearchMedellin 050034Colombia Faculty of Health Sciences Institution University Colegio Mayor de AntioquiaMedellin 050034Colombia Department of Agronomic Sciences National University of ColombiaMedellin 050034Colombia Faculty of Exact Sciences University of AntioquiaMedellin 050010Colombia Department of Microbiology Londrina State UniversityLondrina 86051-990Brazil

At least 20-40% of annual losses of avocado crops are caused by pathogenic *** chemical treatments of these diseases are inefficient,cause environmental pollution and are increasingly restricted by international *** work aimed to assess the biocontrol capacity of a bacterial extract to protect avocado fruits and plants from pathogen *** from the bacterial isolate Serratia ***5.1 were obtained from liquid fermentations in a biorreactor.A body rot postharvest infection model with Colletotrichum gloeosporioides on fruits was ***,packaging conditions were simulated using the bacterial extract and the commercial fungicide prochloraz as a positive ***,seedlings infections with Phytophthora cinnamomi were performed on two types of avocado(West Indian race and ***).The Area Under Disease Progress Curve(AUDPC) was recorded using the bacterial extract and a commercial product with fosetyl-aluminium as *** bacterial extract significantly reduced infections by *** on injured avocado fruits at 31.1 μg mL^-*** fruits were also protected against body rot infections at the same concentration and showed no significant differences with the commercial *** the other hand,AUDPC in the seedlings was significantly reduced with the extract treatment at 3 μg mL^-1 compared to the ***,a possible phytotoxicity effect of the extract was evidenced in the seedlings and confirmed by pathogen recovery and tests on Raphanus sativus ***,formulations of the extracts(emulsion and emulsifiable concentrate) were prepared,and bioactive stability was assessed for 8 *** emulsion formulates demonstrated very stable bioactivity against *** extract and the emulsion formulate showed promising results for the control of avocado *** bioproducts based on this type of active principles could be developed for the benefit of avocado industry.

关键词： Colletotrichum gloeosporioides Phytophthora cinnamomi Serratia sp. antagonistic microbes secondary metabolites biofungicide

Mental health in organizations from a healthcare analytics framework:taxonomic model,trends,and impact of COVID-19

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Journal of Management Analytics 2024年第1期11卷 62-86页

作者： Jorge Iván Pérez Rave carlos Mario Zapata jaramillo Gloria Patricia jaramillo Álvarez IDINNOV research group IDINNOV S.A.SMedellínColombia Department of Computing and Decision Sciences Universidad Nacional de ColombiaMedellínColombia

Mental disorders negatively affect employee well-being and organizational *** face a challenge in terms of how to manage mental *** paper clarifies three issues(underlying patterns,trends,and impact of COVID-19)regarding the scientific study of mental health in organizations from a healthcare analytics *** framework comprises eight stages considering a text-driven approach with scientific corpora assisted by linguistic/computational and statistical *** study discovers a new taxonomic model comprising five patterns in the scientific discourse on the *** analyses reveal imbalances and concerns regarding the interests associated with the patterns,which is reinforced by examining patterns“before”and“during”*** paper complements psychological/epidemiological studies on mental health in organizations from a healthcare analytics perspective.

关键词： Healthcare analytics healthcare management analytics mental health scientific discourse text analytics taxonomy COVID-19 management analytics

Impact of seismic design on tunnels in rock-Case histories

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Underground Space 2017年第2期2卷 106-114页

作者： carlos A.jaramillo COWI North America 1300 Clay Street7th FloorOaklandCA 94612USA

The tunnel industry has considered that tunnels,especially tunnels in rock,are naturally resistant to earthquake action,including faulting,shaking,deflection and ground *** the number of case histories of tunnels subject to earthquake action has increased,the industry has started to recognize that,although tunnels in rock have good resistance against earthquakes generating peak ground accelerations(PGA)lower than 0.5 g,it is important to include the dynamic forces and displacements generated by seismic ground motions in the design process to obtain a more reliable *** additional earthquake forces impact the final design,potentially requiring changes to the ground support and additional reinforcement of the concrete lining,as illustrated by case histories presented in this paper.

关键词： Tunnel Tunnels Seismic design Earthquake impact Tunnel lining Ground support

Helicobacter pylori CagA protein polymorphisms and their lack of association with pathogenesis

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World Journal of Gastroenterology 2010年第31期16卷 3936-3943页

作者： Nicole Acosta Andrés Quiroga Pilar Delgado María Mercedes Bravo carlos jaramillo Molecular Diagnostics and Bioinformatics Laboratory Biological Sciences DepartmentLos Andes University Infectious Agents and Cancer Research Group National Cancer Institute(Colombia)

AIM: To investigate Helicobacter pylori (H. pylori) CagA diversity and to evaluate the association between protein polymorphisms and the occurrence of gastric pathologies. METHODS: One hundred and twenty-two clinical isolates of H. pylori cultured from gastric biopsies obtained from Colombian patients with dyspepsia were included as study material. DNA extracted from isolates was used to determine cagA status, amplifying the C-terminal cagA gene region by polymerase chain reaction. One hundred and six strains with a single amplicon were sequenced and results were used to characterize the 3' variable region of the cagA gene. To establish the number and type of tyrosine phosphorylation motifs Glutamine acid-Proline-Isoleucine-Tyrosine-Alanine (EPI-YA) bioinformatic analysis using Amino Acid Sequence Analyzer-Amino Acid Sequence Analyzer software was conducted. Analysis of the association between the number of EPIYA motifs and the gastric pathology was performed using χ2 test and analysis of the presence of EPIYA-C motifs in relation to the pathology was made by logistic regression odds ratios. Comparisons among EPIYA types found and those reported in GenBank were performed using a proportion test in Statistix Analytical Software version 8.0. RESULTS: After amplification of the 3' of the cagA gene, 106 from 122 isolates presented a single amplicon and 16 showed multiple amplicons. As expected, diversity in the size of the cagA unique fragments among isolates was observed. The 106 strains that presented a single amplicon after 3' cagA amplification came from patients with gastritis (19 patients), atrophic gastritis (21), intestinal metaplasia (26), duodenal ulcer (22) and gastric cancer. DNA sequence analysis showed that the differences in size of 3' cagA unique fragments was attributable to the number of EPIYA motifs: 1.9% had two EPIYA motifs, 62.3% had three, 33.0% had four and 2.8% had five motifs. The majority of tested clinical strains (62.3%) were found to harbor

关键词： Helicobacter pylori CagA-protein polymorphisms Molecular characterization Bioinformatic analysis Pathogenesis Cancer

Eosinophilic esophagitis: Current concepts in diagnosis and treatment

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World Journal of Gastroenterology 2019年第32期25卷 4598-4613页

作者： Andrés Gómez-Aldana Mario jaramillo-Santos Andrés Delgado carlos jaramillo Adán Lúquez-Mindiola Departament of Internal Medicine Section of GastroenterologySanta Fe Foundation of Bogotá(Fundación Santa Fe de Bogotá)Bogotá220246Colombia University of Los Andes Bogotá111711Colombia Department of Endoscopy Caldas UniversityManizales 275Colombia Department of Endoscopy Surgeons’Union SAS(Joint stock company)(Union de cirujanos SAS)Manizales 170001661Colombia Department of Gastroenterology Gut MédicaBogotá110221001Colombia

Eosinophilic esophagitis is an immune-allergic pathology of multifactorial etiology(genetic and environmental)that affects both pediatric and adult *** symptoms,which include heartburn,regurgitation,and esophageal stenosis(with dysphagia being more frequent in eosinophilic esophagitis in young adults and children),are similar to those of gastroesophageal reflux disease,causing delays in diagnosis and *** endoscopic findings such as furrows,esophageal mucosa trachealization,and whitish exudates may suggest its presence,this diagnosis should be confirmed histologically based on the presence of more than 15 eosinophils per high-power field and the exclusion of other causes of eosinophilia(parasitic infections,hypereosinophilic syndrome,inflammatory bowel disease,among others)for which treatment could be ***,the 3“D”s(“Drugs,Diet,and Dilation”)are considered the fundamental components of *** first 2 components,which involve the use of proton pump inhibitors,corticosteroids,immunosuppressants and empirical diets or guided food elimination based on allergy tests,are more useful in the initial phases,whereas endoscopic dilation is reserved for esophageal ***,the most important aspects of eosinophilic esophagitis pathophysiology will be reviewed,in addition to evidence for the various treatments.

关键词： Eosinophilic esophagitis Corticoid Esophageal stenosis Diet Dilation Proton pump inhibitor

Analysis of Double Row Diaphragm Wall Structural Parameters and Their Influences on Foundation Pit Support Structure and Adjacent Ship Lock

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Analysis of Double Row Diaphragm Wall Structural Parameters ...

作者： jaramillo AGUAYO carlos EFREN（永新）华南理工大学

学位级别：硕士

Given China’s constant economic and technological growth,many of the current river ship locks are reaching complete *** lock expansion,at key navigation terminals,is absolutely *** is common practice for new ship locks to be built adjacent to the original ship locks or existing dams and have a certain degree of impact on the existing ship *** this research,structural parameters of the double row diaphragm wall were analyzed with numerical simulation as the main research *** Qingyuan new second line ship lock in Guangdong,China was chosen as the engineering *** double row diaphragm wall is a major part of the braced supporting structure for the deep foundation pit for the new second line ship *** the geotechnical finite element software MIDAS GTS NX,the structural parameters of the supporting structure were *** main contents and results from this paper are as follow:（1）Utilizing MIDAS GTS NX,a 3D finite element model of the new ship lock foundation excavation was *** reliability of the finite element model was verified via comparison with the engineering monitoring data from the engineering case construction and survey *** comparison of the MIDAS GTS NX model was also performed with a model constructed in PLAXIS.（2）Based on the FEM model,the structural parameters of the double row diaphragm wall were studied through single factor sensitivity *** influences on the deformation and stress characteristics of the supporting structure,and displacement of the adjacent ship lock were analyzed.（3）Through orthogonal array testing and multiple finite element simulations,multi factor sensitivity analysis of the structural parameters was *** deformation and stress characteristics of the supporting structure and adjacent ship lock were analyzed to determine the influence of each structural parameter and a possibly more favorable set of parameters.（4）Based on the single and multiple factor

关键词：双排地下连续墙结构参数基坑支护结构邻近船闸

Is the present cut-point to define type 2 diabetes appropriate in Latin-Americans?

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World Journal of Diabetes 2014年第6期5卷 747-755页

作者： Patricio López-jaramillo carlos Velandia-Carrillo Diego Gómez-Arbeláez Martin Aldana-Campos Dirección de Investigaciones Clínica de Síndrome MetabólicoPrediabetes y DiabetesFundación Oftalmo-lógica de Santander-FOSCAL Instituto de Investigaciones MASIRA Facultad de MedicinaUniversidad de Santander-UDES Departamento de Medicina Interna Universidad Autónoma de Bucaramanga División de Endocrinología Escuela de MedicinaUniversidad de Santiago de Compostela

The diagnosis of diabetes mellitus type 2(DM2) is based either on increased plasma glucose or Glycated hemoglobin levels. Since these measures are the only means for diagnosis of DM2, they must be well adapted to each population according to their metabolic characteristics, given that these may vary in each population. The World Health Organization(WHO) determined the cut-points of plasma glucose levels for the diagnosis of DM2 by associating hyperglycemia with the risk of a specific microvascular complication-retinopathy. Cardiovascular diseases are however the principal causes of mortality in patients with DM2 and we reported that in the Colombo-Ecuadorian population impaired fasting glucose and impaired glucose tolerance are both riskmarkers for myocardial infarction. We propose that the current cut-points accepted by the WHO need to be revaluated in populations such as Latin America and that there should be lower cut points for glycaemia in this population, to reduce the prevalence of cardiovascular complications associated with DM2.

关键词： Type 2 diabetes Cut-off points Cardiovascular diseases Plasma glucose Coronary disease

The 40th AASP Meeting in Panama

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Episodes 2008年第3期31卷 354-354页

作者： jaramillo, carlos Ctr Trop Paleoecol & Archeol Balboa Panama

The American Association of Stratigraphic Palynologists （AASP） held its 40th annual meeting this year in Panama City, Panama from 9-12 September. Meeting organizer and AASP president carlos jaramillo （Smithsonian Tropical Research Institute, Panama） received 50 abstracts from 18 coun- tries. There were 68 attendees, a quarter of them students. This year＇s meeting was spon- sored by： AASP, ExxonMobil,

关键词：地层学巴拿马国际会议会议组织

Heritage risk index:A multi-criteria decision-making tool to prioritize municipal historic preservation projects

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Frontiers of Architectural Research 2020年第2期9卷 403-418页

作者： Jonathan Ruiz-jaramillo Carmen Munoz-Gonzalez Maria Dolores Joyanes-Diaz Eduardo Jimenez-Morales Jose Manuel Lopez-Osorio Roberto Barrios-Perez carlos Rosa-Jimenez Department of Art and Architecture School of ArchitectureUniversidad de MalagaMalaga 29071Spain

The current pressure on the built historical heritage requires a global evaluation to develop strategies for its preservation.A combined vision of the state of conservation of architectural heritage is essential to highlight the vulnerabilities of the structure from which harmonized measures can be proposed for its *** study proposes a multi-criteria analysis methodology that considers a qualitative and quantitative approach to organize the global conservation state of heritage buildings hierarchically.A global index can be determined on the basis of the generation of an interoperable data matrix by defining a set of indicators to assess different components of a *** index describes the risk with respect to the stability,safety,and habitability of the *** methodology aims to achieve the state of the building in an integral way by obtaining a simple and objective index that enables efficient comparison among different *** application of this methodology to a historic area allows creating a hierarchical map of risk to stablish priorities for intervention and enable a sustainable and critical management and planning over the actions of maintenance,conservation,and *** this way,a holistic vision of the complex reality of built heritage and the urban landscape is obtained to identify critical areas of priority intervention.

关键词： Historic city State of conservation Risk index Intervention priority Architectural heritage