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Extreme biomimetic approach for developing novel chitin-GeO2 nanocomposites with photoluminescent properties

Nano Research 2015年第7期8卷 2288-2301页

作者： Marcin Wysokowski Mykhailo Motylenko Jan Beyer Anna Makarova Hartmut Stocker Juliane Walter Roberta Galli Sabine Kaiser Denis Vyalikh Vasilii V. Bazhenov laroslav Petrenko Allison l Stelling Serguei l. Molodtsovs Dawid Stawski Krzysztof J.Kurzydfowski Enrico langer Mikhail V Tsurkan Teofil Jesionowski Johannes Heitmann Dirk C. Meyer Hermann Ehrlich Institute of Chemical Technology and Engineering Poznan University of Technology 60965 Poznan Poland Institute of Materials Science TU Bergakademie Freiberg 09599 Freiberg Germany Institute of Applied Physics TU Bergakademie Freiberg 09599 Freiberg Germany Institute of Solid State Physics Dresden University of Technology 01069 Dresden Germany Institute of Experimental Physics TU Bergakademie Freiberg 09599 Freiberg Germany Faculty of Medicine carl Gustav Carus Department of Anaesthesiology and Intensive Care Medicine Clinical Sensoring and Monitoring TU Dresden 01069 Dresden Germany epartment of Physics St. Petersburg State University 198504 St. Petersburg Russia Department of Mechanical Engineering and Materials Science Duke University 27708 Durham NC USA European X-Ray Free-Electron laser Facility (XFEl) GmbH 22761 Hamburg Germany ITMO University 197101 St. Petersburg Russia Department of Commodity and Material Sciences and Textile Metrology Technical University of Lodz 90924 LSdz Poland Materials Design Group Faculty of Materials Science and Engineering Warsaw University of Technology PL-02507 Warsaw Poland Institute of Semiconductors and Microsystems TU Dresden 01062 Dresden Germany leibniz Institute of Polymer Research Max Bergmann Centre for Biomaterials 01062 Dresden Germany

This work presents an extreme biomimetics route for the creation of nano- structured biocomposites utilizing a chitinous template of poriferan origin. The specific thermal stability of the nanostructured chitinous template allowed for the formation under hydrothermal conditions of a novel germanium oxide- chitin composite with a defined nanoscale structure. Using a variety of analytical techniques （FTIR, Raman, energy dispersive X-ray （EDX）, near-edge X-ray absorption fine structure （NEXAFS）, and photoluminescence （Pl） spectroscopy, EDS-mapping, selected area for the electron diffraction pattern （SAEDP）, and transmission electron microscopy （TEM））, we showed that this bioorganic scaffold induces the growth of GeO2 nanocrystals with a narrow （150-300 nm） size distri- bution and predominantly hexagonal phase, demonstrating the chitin template＇s control over the crystal morphology. The formed GeO2-chitin composite showed several specific physical properties, such as a striking enhancement in photo- luminescence exceeding values previously reported in GeOR-based biomaterials. These data demonstrate the potential of extreme biomimetics for developing new-generation nanostructured materials.

关键词： extreme biomimetics, chitin-GeO2 photoluminescence, near-edge X-ray absorption fine structure (NEXAFS) spectroscopy

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Study of the Orthoptic Assessment in Refractive Eye Surgery

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Open Journal of Ophthalmology 2020年第1期10卷 55-58页

作者： l. Sabetti M. Ciancaglini F. Guetti l. laglia G. Murano Department of Biotechnological and Applied Clinical Sciences University of L’Aquila L’Aquila Italy Departmente of life Health & Environmental Sciences L’Aquila Italy

Purpose: The aim of our study was to assess the variations in fusion and stereopsis before and after refractive surgery. Methods: We conducted a retrospective study. 140 patients (78 M, 62 F) were selected, aged 20 - 59 years (mean age 36 ± 10 DS). All patients received a comprehensive ophtalmological and orthoptic examination. Surgery was performed using a MEl-80 excimer laser (carl Zeiss Meditec, Jena, Germany). Results: Fusional convergence amplitudes after refractive eye surgery range from at near 18 - 20 PD in 42 (30%) patients;25 - 30 PD in 56 (40%) patients;35 - 40 PD in 42 (30%) patients, at far 20 - 25 PD in 84 (60%) patients;30 - 40 PD in 56 (40%) patients, fusional divergence at near after refractive eye surgery range from at near 6 - 8 PD in 108 (75.7%) patients;10 - 12 PD in 52 (37.1%), at far 6 - 8 PD in 126 (90%) patients;10 - 12 PD in 14 (10%) patients. None of the patients developed any ocular deviations. NCP, on average, decreases from 9.4 ± 1.5 cm to 9.1 ± 0.9 cm after. None of these patients with a normal NCP before surgery developed an abnormal NCP after refractive surgery. Eighteen patients (12.8%) had a stereopsis higher than 60 s of arch before surgical intervention. Of these, in 2 cases (2.8%) stereopsis increased from 200 to 40 s of arch after surgery. In the rest of patients stereopsis remained unchanged. Conclusion: The increase in fusion at near appears to be considerably interesting, whereas there is no worsening of stereopsis. A careful pre-surgery orthoptic evaluation is extremely revelant for a safe refractive surgery, this reducing the risk of complications associated with fusion and stereopsis.

关键词： Orthoptic Refractive Excimer Fusion Stereopsis Convergence

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激进主义一代的日记(1968-2008)

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世界哲学 2008年第5期 42-48页

作者： l.兰格曼周穗明美国芝加哥罗约拉大学中国社会科学院哲学研究所

本文是l.兰格曼论1968年运动的数万字长文的导言和结论两部分。作者在概括西方新社会运动40年的发展,全面考察1968年运动的起源、后果和意义的基础上,提出了三个观点:1.1968年运动是政治上进步的变革运动,继承了启蒙的民主化事业,是未... 详细信息

本文是l.兰格曼论1968年运动的数万字长文的导言和结论两部分。作者在概括西方新社会运动40年的发展,全面考察1968年运动的起源、后果和意义的基础上,提出了三个观点:1.1968年运动是政治上进步的变革运动,继承了启蒙的民主化事业,是未来世界政治变化的先兆;2.1968年运动是关于包容和承认的文化变化的里程碑,标志着社会运动目标从利益到文化、身份和生活方式的转折;3.1968年运动不是对社会的根本改造,其主要成就是形成了构成运动本质的身份认同、共同体和意义。

关键词： 1968 激进主义者社会运动全球正义运动

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NEW QUAlITY ASSESSMENT PARAME-TERS FOR OCT 3

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国际眼科杂志 2003年第1期3卷 121-122页

作者： H.Ishikawa R.Hariprasad G.Wollstein l.A.Paunescu l.l.Price P.Stark J.G.Fujimoto J.S.Schuman Tufts-New England Medical Center Tufts University School of Medicine New England Eye Center MATufts-New England Medical Center Tufts University School of Medicine New England Eye Center MATufts-New England Medical Center Tufts University School of Medicine New England Eye Center MATufts-New England Medical Center Tufts University School of Medicine New England Eye Center MATufts-New England Medical Center Tufts University School of Medicine New England Eye Center MATufts-New England Medical Center Tufts University School of Medicine New England Eye Center MADepartment of Electrical Engineering and Computer Sci-ence and Research Laboratory of Electronics Massachusetts In-stitute of Technology MA USATufts-New England Medical Center Tufts University School of Medicine New England Eye Center MA

Purpose: To develop a method to evaluate the quality of optical coherence tomography (OCT 3, carl Zeiss Meditec Inc., Dublin, CA) images in a quantitative and objective fashion. Methods: Raw data files of OCT 3 images (linear macular scan, peripapil-lary circular scan, and optic nerve head scan) were exported and analyzed using a software program of our own design. We de-

关键词：光学相干X断层照相质量控制评价 OCT图像

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Direct laser writing of volumetric gradient index lenses and waveguides

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light(Science & Applications) 2020年第1期9卷 89-102页

作者： Christian R.Ocier Corey A.Richards Daniel A.Bacon-Brown Qing Ding Raman Kumar Tanner J.Garcia Jorik van de Groep Jung-Hwan Song Austin J.Cyphersmith Andrew Rhode Andrea N.Perry Alexander J.littlefield Jinlong Zhu Dajie Xie Haibo Gao Jonah F.Messinger Mark l.Brongersma Kimani C.Toussaint Jr lynford l.Goddard Paul V.Braun Department of Materials Science and Engineering University of Illinois at Urbana-ChampaignUrbanaILUSA Materials Research laboratory University of Illinois at Urbana-ChampaignUrbanaILUSA Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-ChampaignUrbanaILUSA Department of Electrical and Computer Engineering University of Illinois at Urbana-ChampaignUrbanaILUSA Department of Materials Science and Engineering Stanford UniversityStanfordCAUSA carl R.Woese Institute for Genomic Biology University of Illinois at Urbana-ChampaignUrbanaILUSA Department of Mechanical Science and Engineering University of Illinois at Urbana-ChampaignUrbanaILUSA

Direct laser writing(DlW)has been shown to render 3D polymeric optical components,including lenses,beam expanders,and mirrors,with submicrometer ***,these printed structures are limited to the refractive index and dispersive properties of the ***,we present the subsurface controllable refractive index via beam exposure(SCRIBE)method,a lithographic approach that enables the tuning of the refractive index over a range of greater than 0.3 by performing DlW inside photoresist-filled nanoporous silicon and silica *** the laser exposure during printing enables 3D submicron control of the polymer infilling and thus the refractive index and chromatic *** SCRIBE’s unprecedented index range and 3D writing accuracy has realized the world’s smallest(15μm diameter)spherical luneburg lens operating at visible ***’s ability to tune the chromatic dispersion alongside the refractive index was leveraged to render achromatic doublets in a single printing step,eliminating the need for multiple photoresins and writing *** also has the potential to form multicomponent optics by cascading optical elements within a *** a demonstration,stacked focusing structures that generate photonic nanojets were fabricated inside porous ***,an all-pass ring resonator was coupled to a subsurface 3D *** measured quality factor of 4600 at 1550 nm suggests the possibility of compact photonic systems with optical interconnects that traverse multiple *** is uniquely suited for constructing such photonic integrated circuits due to its ability to integrate multiple optical components,including lenses and waveguides,without additional printed supports.

关键词： index refractive render

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Suppression of the External MitochondrialNADPH Dehydrogenase, NDB1, in Arabidopsisthaliana Affects Central Metabolism andVegetative Growth

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Molecular Plant 2014年第2期7卷 356-368页

作者： Sabá V. Wallström Igor Florez-Sarasa Wagner l. Araújo Mari Aidemark María Fernández-Fernández Alisdair R. Fernie Miquel Ribas-Carbó Allan G. Rasmusson Department of Biology Lund University Biology building Sölvegatan 35 SE-223 62 Lund Sweden Grup de Recerca en Biologia de les Plantes en Condicions Mediterrànies Universitat de les Illes Balears Ctra Valldemossa Km. 75 07122 Palma de Mallorca Spain Present address: Max-Planck-Institut für Molekulare Pflanzenphysiologie Am Mühlenberg 1 14476 Potsdam-Golm Germany Max-Planck-Institut für Molekulare Pflanzenphysiologie Am Mühlenberg 1 14476 Potsdam-Golm Germany Present address: Departamento de Biologia Vegetal Universidade Federal de Viçosa 36570-000 Viçosa Minas Gerais Brasil

Ca2＋-dependent oxidation of cytosolic NADPH is mediated by NDB1, which is an external type II NADPHdehydrogenase in the plant mitochondrial electron transport chain. Using RNA interference, the NDB1 transcript wassuppressed by 80% in Arabidopsis thaliana plants, and external Ca2＋-dependent NADPH dehydrogenase activity becameundetectable in isolated mitochondria. This was linked to a decreased level of NADP＋ in rosettes of the transgenic ***-grown transgenic seedlings displayed decreased growth specifically on glucose, and respiratory metabolism of 14C-glucose was increased. On soil, NDBl-suppressing plants had a decreased vegetative biomass, but leaf maximumquantum efficiency of photosystem Ⅱ and CO2 assimilation rates, as well as total respiration, were similar to the wild-type. The in vivo alternative oxidase activity and capacity were also similar in all genotypes. Metabolic profiling revealeddecreased levels of sugars, citric acid cycle intermediates, and amino acids in the transgenic lines. The NDBl-suppressioninduced transcriptomic changes associated with protein synthesis and glucosinolate and jasmonate metabolism. Thetranscriptomic changes also overlapped with changes observed in a mutant lacking ABAINSENSITIVE4 and in A. thalianaoverexpressing stress tolerance genes from rice. The results thus indicate that A. thaliana NDB1 modulates NADP（H）reduction levels, which in turn affect central metabolism and growth, and interact with defense signaling.

关键词： citric acid cycle metabolic profiling mitochondrial respiration NADPH RNA interference type II NAD(P)Hdehydrogenase vegetative growth

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人类与自然耦合系统

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AMBIO－人类环境杂志 2007年第B12期36卷 602-611页

作者：刘建国 Thomas Dietz Stephen R.Carpenter carl Folke Marina Alberti Charles l.Redman Stephen H.Schneider Elinor Ostrom Alice N.Pell Jane lubchenco William W.Taylor 欧阳志云 Peter Deadman Timothy Kratz William Provencher 张淑敏密歇根州立大学美国威斯康星大学瑞典皇家科学院贝耶学院华盛顿大学亚利桑那州立大学斯坦福大学亚利桑那州立大学制度多样性研究中心康奈尔大学的康奈尔国际食品农业与发展学院俄勒冈州立大学密歇根州立大学鱼类和野生动植物系中国科学院生态环境研究中心国家城市和区域生态重点实验室沃特卢大学地理系威斯康星州大学的威斯康星大学鳟鱼湖站威斯康星大学

人类与自然系统不断地相互作用促使人类与自然耦合系统(CHANS)的形成与发展。近期的研究揭示了人类与自然耦合系统在组织、空间以及时间上耦合的复杂性。这些耦合在相互作用方面从直接演化到更间接;在联结方面从邻近演化到更远距离;在... 详细信息

人类与自然系统不断地相互作用促使人类与自然耦合系统(CHANS)的形成与发展。近期的研究揭示了人类与自然耦合系统在组织、空间以及时间上耦合的复杂性。这些耦合在相互作用方面从直接演化到更间接;在联结方面从邻近演化到更远距离;在尺度上,从局部演化到全球;在模式和过程上,从简单演化到复杂。解开如相互影响和突发属性的复杂性,能够导致新的科学发现,并且对于开发生态和社会经济可持续性的有效政策是非常重要的。以解决关于人类与自然耦合系统的基本问题和迎接社会的空前挑战为目的的,真正整合不同学科的机会正显现出来。

关键词：耦合系统自然系统人类相互作用社会经济科学发现可持续性复杂性

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Genetic reporter analysis reveals an expandable reservoir of OCT4+cells in adult skin

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Cell Regeneration 2014年第1期3卷 63-68页

作者： Anne limbourg Sabine Schnabel Vladimir J lozanovski l Christian Napp Teng-Cheong Ha Tobias Maetzig Johann Bauersachs Hassan Y Naim Axel Schambach Florian P limbourg Research Group Regenerative Agents HannoverGermany REBIRTH Cluster of Excellence HannoverGermany Integrated Research Center Transplantation(IFB-Tx) HannoverGermany Current affiliation:Department of Plastic Hand and Reconstructive SurgeryHannoverGermany Department of Cardiology and Angiology HannoverGermany Institute of Experimental Hematology OE6960 Hannover Medical SchoolCarl-Neuberg-Str.1D-30625 HannoverGermany Department of Physiological Chemistry Hannover Veterinary SchoolHannoverGermany Division of Hematology/Oncology Boston Children’s HospitalHarvard Medical SchoolHarvardUSA Department of Nephrology and Hypertension Hannover Medical SchoolHannoverGermany Department of General and Transplant Surgery University Hospital HeidelbergHeidelbergGermany Vascular Medicine and Transplantation Research Dept.of Nephrology and HypertensionOE 6841Hannover Medical SchoolCarl-Neuberg-Str.1D-30625 HannoverGermany

The transcription factor Oct4(Pou5f1)is a critical regulator of pluripotency in embryonic and induced pluripotent stem ***,Oct4 expression might identify somatic stem cell populations with inherent multipotent potential or a propensity for facilitated ***,analysis of Oct4 expression is confounded by Oct4 pseudogenes or non-pluripotency-related *** analysis of a transgenic Oct4-EGFP reporter mouse identified testis and skin as two principle sources of Oct4^(+)cells in postnatal *** the prevalence of GFP^(+)cells in testis rapidly declined with age,the skin-resident GFP^(+)population expanded in a cyclical *** cells were identified as epidermal stem cells dwelling in the stem cell niche of the hair follicle,which endogenously expressed all principle reprogramming factors at low ***,skin wounding or non-traumatic hair removal robustly expanded the GFP^(+)epidermal cell pool not only locally,but also in uninjured skin areas,demonstrating the existence of a systemic ***,the epithelial stem cell niche of the hair follicle harbors an expandable pool of Oct4^(+)stem cells,which might be useful for therapeutic cell transfer or facilitated reprogramming.

关键词： Oct4 Epidermal stem cells Skin Transgenic reporter mice

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钻井泥浆泵的研究和使用

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石油矿场机械 1980年第5期 3-3页

作者： Samluel l.Collier carl Aalund N.B.Heaps Walter E.liljestrand Clarence Reid

本文最初发表在美国《World Oil》杂志,147卷,1、2、4、5、6、7期;148卷,2、4、5、7期及149卷,1、2期。全文共十二个部分,原文总题目为《Know You Mud Pump-It Can SaveYou Money》。本文是美国米兴公司(Mission)发展研究部的一组试验... 详细信息

本文最初发表在美国《World Oil》杂志,147卷,1、2、4、5、6、7期;148卷,2、4、5、7期及149卷,1、2期。全文共十二个部分,原文总题目为《Know You Mud Pump-It Can SaveYou Money》。本文是美国米兴公司(Mission)发展研究部的一组试验研究报告。它以试验为依据,对泥浆泵本身,吸入系统,排出系统三个基本方面进行了分析和论述;系统地提出了许多包括测试方法在内的研究泥浆泵系统的基本方法、公式、曲线和图表,并指出了一些符

关键词：泥浆泵杂质泵美国美利坚合众国北美洲

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Rare case of perforated giant gastric ulcer with concurrent thyroid storm:A case report

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World Journal of Surgical Procedures 2022年第1期12卷 8-12页

作者： Jasper Xiangwei Wang lin Seong Soh Dinesh carl Junis Mahendran Chang Yi Woon Clement luck Khng Chia Department of General Surgery Khoo Teck Puat HospitalSingapore 768828Singapore Department of Endocrinology Khoo Teck Puat HospitalSingapore 768828Singapore Yong loo lin School of Medicine National University of SingaporeSingapore 117597Singapore

BACKGROUND Thyroid storm is an uncommon condition manifesting in severe thyrotoxicosis with a high mortality *** concurrence of peptic ulcer disease and hyperthyroidism is rare due to concurrent activation of both the sympathetic and parasympathetic *** present a case of perforated giant gastric ulcer with concurrent thyroid storm who underwent damage control surgery with emergency patch repair with falciform ligament and recovered *** SUMMARY A 53-year-old male chronic smoker,with no previous medical history,presented with severe generalized abdominal pain and vomiting for one day *** history revealed weight loss,diarrhea,and anxiety over the past three *** clinical examination,patient was febrile with temperature of 38.6 Degrees Celsius and tachycardic at 130-140 beats per minute,his blood pressure was low at 90/*** abdomen was tender with generalized *** view of his clinical history,a thyroid screen was ordered which showed raised thyroxine(T4)levels of 90.3 pmol/l and low thyroxine stimulating hormone(TSH)levels of 0.005μU/*** X-ray showed no sub-diaphragmatic free air,but contrasted CT scan revealed pneumoperitoneum with large amount of intraabdominal free *** working diagnosis was perforated peptic ulcer complicated by thyroid *** urgent endocrinologist consult was made,and patient was started on beta blocker and intravenous steroids *** patient underwent emergency laparotomy with washout and patch repair of the perforated gastric *** was monitored post-operatively in intensive care unit and required IV hydrocortisone and lugol’s *** of the ulcer edges showed no *** post-operative day seven,T4 decreased to 20.4 pmol/l,TSH was 0.005 mlU/*** thyroid function test subsequently normalized 3 mo post-operatively with T418.1 pmol/l,TSH 1.91 mlU/***’s recovery was otherwise *** receptor antibody subsequently was positive,and pa

关键词： Peptic ulcer Perforated viscus Thyroid storm Multidisciplinary Grave’s disease Case report

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