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Chinese Medical Journal 2013年第15期126卷 2984-2986页

作者： cao hai-long song shu-li yang bo-li zhang zhi-hua zhang hui qu rui wang bang-mao Tianjin Med Univ Dept Gastroenterol & Hepatol Gen Hosp Tianjin 300052 Peoples R China Cangzhou Peoples Hosp Dept Gastroenterol & Hepatol Cangzhou 061000 Heibei Peoples R China Anhui Med Univ Dept Epidemiol Hefei 230032 Anhui Peoples R China

Sporadic fundic gland polyps （FGPs） account for 0.8%- 1.9% of all gastric polyps and are observed in patients undergoing esophagogastroduodenoscopy （EGD） in whom they account for more than 50% of all gastric polyps. The prevalence is increasing in recent years possibly due to decreased Helicobacter pylori （1t. pylori） infection rate and long-term proton pump inhibitor use. Generally, sporadic FGPs are assumed to be benign polyps with no risk of malignant transformation. We evaluated the feasibility of predicting sporadic FGPs based on typical endoscopic appearance in a large database of 47 771 endoscopies.

关键词： fundic gland polyps stomach neoplasms dysplasia endoscopy, gastrointestinal

Study of the response of 10B-doped MCP to wide-energy range neutrons from eV to MeV

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Nuclear Science and Techniques 2024年第8期35卷 132-141页

作者： Qiang li li‑Jiao wang Xiang‑Biao Qiu Jing‑Wen li Wei Xu Tao li Ze‑Bin lin Chang‑Jun Ning Yong‑Hao Chen rui‑rui Fan Kang Sun Jing‑Yu Tang Rong zhang Han‑Tao Jing bo Mei Qi An Hao‑Fan Bai Jiang‑bo Bai Jie Bao Ping cao Qi‑Ping Chen Zhen Chen Zeng‑Qi Cui An‑Chuan Fan Chang‑Qing Feng Fan‑Zhen Feng Ke‑Qing Gao Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑Zhu He Yong‑Cheng He yang Hong Yi‑Wei Hu Han‑Xiong huang Wei‑hua Jia Hao‑Yu Jiang Wei Jiang zhi‑Jie Jiang Zheng‑Yao Jin ling Kang bo li Chao li Gong li Jia‑Wen li Xiao li yang li Jie liu Rong liu shu‑Bin liu Guang‑Yuan Luan Bin‑Bin Qi Jie Ren zhi‑Zhou Ren Xi‑Chao Ruan Zhao‑hui song zhi‑Xin Tan Sheng‑Da Tang Peng‑Cheng wang Zhao‑hui wang Zhong‑Wei Wen Xiao‑Guang Wu Xuan Wu li‑Kun Xie Yi‑Wei yang Han Yi Yong‑Ji Yu Guo‑hui zhang lin‑Hao zhang Mo‑Han zhang Qi‑Wei zhang Xian‑Peng zhang Yu‑liang zhang Yue zhang zhi‑Yong zhang mao‑Yuan Zhao Lu‑Ping Zhou zhi‑Hao Zhou Ke‑Jun Zhu Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Dongguan songshan Lake Future School Dongguan 523808China North Night Vision Science&Technology(Nanjing)Research Institute Co.Ltd. Nanjing 211106China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Neutron-sensitive microchannel plates(nMCPs)have applications in neutron detection,including energy spectrum measurements,neutron-induced cross sections,and neutron imaging.10B-doped MCPs(B-MCPs)have attracted significant attention owing to their potential for exhibiting a high neutron detection efficiency over a large neutron energy *** spatial and temporal resolutions are useful for neutron energy-resolved ***,their practical applications still face many technical *** this study,a B-MCP with 10 mol%10B was tested for its response to wide-energy neutrons from eV to MeV at the Back-n white neutron source at the China Spallation Neutron *** neutron detection efficiency was calibrated at 1 eV,which is approximately 300 times that of an ordinary MCP and indicates the success of 10 B *** factors that caused the reduction in the detection efficiency were simulated and *** neutron energy spectrum obtained using B-MCP was compared with that obtained by other measurement methods,and showed very good consistency for neutron energies below tens of *** response is more complicated at higher neutron energy,at which point the elastic and nonelastic reactions of all nuclides of B-MCP gradually become *** is beneficial for the detection of neutrons,as it compensates for the detection efficiency of B-MCP for high-energy neutrons.

关键词： Neutron radiation image 10B-doped MCP Neutron response Wide-energy range neutrons

Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

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Nuclear Science and Techniques 2024年第1期35卷 178-187页

作者： Sheng-Da Tang Yong-Hao Chen Jing-Yu Tang rui-rui Fan Qiang li Gong li Dong liu Zheng-Yao Jin Xing-Zhu Cui Tian-Xiang Chen Yi-Wei yang Rong liu Han Yi yang li Zhen yang Qi An Hao-Fan Bai Jiang-bo Bai Jie Bao Ping cao Qi-Ping Chen Zhen Chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He yang Hong Yi-Wei Hu Han-Xiong huang Wei-hua Jia Hao-yu Jiang Wei Jiang zhi-jie Jiang ling Kang bo li Chao li Jia-Wen li Xiao li Jie liu shu-Bin liu Guang-Yuan Luan Chang-Jun Ning Bin-Bin Qi Jie Ren zhi-Zhou Ren Xi-Chao Ruan Zhao-hui song Kang Sun zhi-Xin Tan li-Jiao wang Peng-Cheng wang Zhao-hui wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu li-Kun Xie Yong-Ji Yu Guo-hui zhang lin-Hao zhang Mo-Han zhang Qi-Wei zhang Xian-Peng zhang Yu-liang zhang Yue zhang zhi-Yong zhang mao-Yuan Zhao Lu-Ping Zhou zhi-Hao Zhou Ke-Jun Zhu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Institute of High-Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China USTC Archaeometry Laboratory University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Nondestructive and noninvasive neutron assays are essential applications of neutron *** resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental composition of an *** back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRTA method for nuclide identification was conducted at the CSNS Back-n via two test *** results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRTA method at *** study reveals its potential future applications.

关键词： CSNS White neutron beam NRTA Nuclide identification Nondestructive method

Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China:A national multicenter survey of 35,566 individuals

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan liu rui-Xia Ma Xian-Bao cao hua zhang shui-Hong Zhou Wei-Hong Jiang Yan Jiang Jing-Wu Sun Qin-Tai yang Xue-Zhong li Ya-Nan Sun li Shi Min wang Xi-Cheng song Fu-quan Chen Xiao-shu zhang Hong-quan Wei Shao-Qing Yu Dong-Dong Zhu Luo Ba zhi-Wei cao Xu-Ping Xiao Xin Wei zhi-Hong lin Feng-Hong Chen Chun-Guang Shan Guang-Ke wang Jing Ye Shen-Hong qu Chang-Qing Zhao Zhen-lin wang hua-Bin li Feng liu Xiao-bo Cui Sheng-Nan Ye Zheng liu Yu Xu Xiao Cai Wei huang Ru-Xin zhang Yu-lin Zhao Guo-Dong Yu Guang-Gang Shi Mei-Ping Lu yang Shen Yu-Tong Zhao Jia-Hong Pei Shao-Bing Xie long-Gang Yu Ye-hai liu Shao-Wei Gu Yu-Cheng yang Lei Cheng Jian-Feng liu Graduate School of Beijing University of Chinese Medicine BeijingChina Department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina Department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina Department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina Department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina Department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina Department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and Prevention LanzhouChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 28,2022,and February 21,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.29 and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12 days,respectively,with 0.5%of patients having symptoms lasting for more than 28 *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2 virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2 vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis bodrov Anton bogomyagkov Serge bondarenko Stewart boogert Maarten boonekamp Marcello borri Angelo bosotti Vincent boudry Mohammed boukidi Igor boyko Ivanka bozovic Giuseppe bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai haiying Cai huacheng Cai Lorenzo Calibbi Junsong Cang Guofu cao Jianshe cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen hua-Xing Chen huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen boping Chen Chunhui Chen Hok Chuen Cheng huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core shuangxue Deng Wei-Tian Deng zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

2019—2020年160例儿童肺炎链球菌脑膜炎临床流行病学多中心研究

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中国当代儿科杂志 2024年第2期26卷 131-138页

作者：王彩云许红梅刘钢刘静俞蕙陈必全郑帼舒敏杜丽君徐志伟黄丽素李海波汪东白松婷单庆文朱春晖田健美郝建华林爱伟林道炯吴谨准张新华曹清陶仲宾陈源朱国龙薛萍汤正珍苏学文曲政海赵仕勇庞琳邓慧玲舒赛男陈英虎浙江大学医学院附属儿童医院感染科浙江杭州310052 重庆医科大学附属儿童医院感染科重庆400014 首都医科大学附属北京儿童医院感染科北京100045 湖南省儿童医院感染科湖南长沙410007 复旦大学附属儿科医院感染科上海201102 安徽省儿童医院感染科安徽合肥230022 南京医科大学附属儿童医院神经科江苏南京210008 四川大学华西第二医院儿科四川成都610044 山西省儿童医院神经内科山西太原030006 温州医科大学附属第二医院/育英儿童医院普儿科浙江温州325027 上海交通大学医学院附属新华医院感染科上海200092 吉林大学第一医院儿科门诊吉林长春130061 西安交通大学附属儿童医院陕西西安710002 郑州大学第一附属医院儿科河南郑州450052 广西医科大学第一附属医院儿科广西南宁530021 江西省儿童医院感染科江西南昌330006 苏州大学附属儿童医院感染科江苏苏州215002 河南开封市儿童医院感染科河南开封475000 山东大学儿童院感染科山东济南250022 海南省妇幼保健院感染科海南海口571103 厦门大学附属妇女儿童医院儿科福建厦门361003 山西省儿童医院新生儿科山西太原030006 上海交通大学医学院附属上海儿童医学中心感染科上海200127 兰州大学第一医院儿科甘肃兰州730013 河北医科大学第二医院儿科河北石家庄050004 青海省妇女儿童医院感染消化科青海西宁810007 太原市妇幼保健院儿内科山西太原030012 遵义市第一人民医院儿科贵州遵义563099 内蒙古自治区人民医院儿科内蒙古呼和浩特750306 青岛大学附属医院儿科山东青岛266003 杭州市儿童医院感染科浙江杭州310005 首都医科大学附属北京地坛医院儿科北京100102 西安市中心医院儿科陕西西安710004 华中科技大学同济医学院附属同济医院儿科湖北武汉430030

目的研究中国儿童肺炎链球菌脑膜炎(pneumococcal meningitis,PM)的临床特征、转归和分离菌株肺炎链球菌(Streptococcus pneumoniae,SP)的药物敏感性。方法回顾性分析2019年1月—2020年12月全国33家三级甲等医院160例<15岁的PM住院患儿... 详细信息

目的研究中国儿童肺炎链球菌脑膜炎(pneumococcal meningitis,PM)的临床特征、转归和分离菌株肺炎链球菌(Streptococcus pneumoniae,SP)的药物敏感性。方法回顾性分析2019年1月—2020年12月全国33家三级甲等医院160例<15岁的PM住院患儿的临床信息、实验室资料和微生物学资料。结果160例PM患儿中,男103例,女57例;年龄15 d至15岁,其中3月龄至<3岁109例(68.1%)。脑脊液培养分离SP菌株95例(59.4%),血培养分离SP菌株57例(35.6%)。脑脊液宏基因组二代测序和脑脊液SP抗原检测阳性率分别为40%(35/87)、27%(21/78)。55例(34.4%)患儿存在1个或多个化脓性脑膜炎高危因素;113例(70.6%)患儿有1个或多个颅外感染病灶;18例(11.3%)有明确基础疾病。临床症状以发热最常见(147例,91.9%),其次是精神萎靡(98例,61.3%)、呕吐(61例,38.1%)等。69例(43.1%)患儿住院期间发生颅内并发症,常见并发症为硬膜下积液和/或积脓(43例,26.9%)、脑积水(24例,15.0%)、脑脓肿(23例,14.4%)、脑出血(8例,5.0%)。硬膜下积液和/或积脓和脑积水主要发生在<1岁患儿,分别为91%(39/43)、83%(20/24)。SP菌株对万古霉素(100%,75/75)、利奈唑胺(100%,56/56)、厄他培南(100%,6/6)完全敏感;对左氧氟沙星(81%,22/27)、莫西沙星(82%,14/17)、利福平(96%,25/26)和氯霉素(91%,21/23)敏感率高;对青霉素(16%,11/68)、克林霉素(6%,1/17)敏感率低;对红霉素完全耐药(100%,31/31)。痊愈和好转出院率分别为22.5%(36/160)、66.2%(106/160);18例(11.3%)出现不良结局。结论儿童PM多见于3月龄至<3岁婴幼儿,颅内并发症多发生在<1岁患儿,发热是PM患儿最常见的临床表现,硬膜下积液和/或积脓、脑积水是最常见的并发症。脑脊液非培养检测方法有助于提高病原菌检出率。超过10%PM患儿出现不良结局。SP菌株对万古霉素、利奈唑胺、厄他培南、左氧氟沙星、莫西沙星、利福平、氯霉素敏感率高。

关键词：肺炎链球菌脑膜炎流行病学多中心研究儿童

基于白光中子源的^(197)Au中子辐射俘获截面测量及共振参数分析

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物理学报 2024年第7期73卷 104-113页

作者：罗淏天张奇玮栾广源王晓宇邹翀任杰阮锡超贺国珠鲍杰孙琪黄翰雄王朝辉吴鸿毅顾旻皓余滔解立坤陈永浩安琪白怀勇鲍煜曹平陈昊磊陈琪萍陈裕凯陈朕崔增琪樊瑞睿封常青高可庆韩长材韩子杰何泳成洪杨黄蔚玲黄锡汝季筱璐吉旭阳蒋伟江浩雨姜智杰敬罕涛康玲康明涛李波李超李嘉雯李论李强李晓李样刘荣刘树彬刘星言穆奇丽宁常军齐斌斌任智洲宋英鹏宋朝晖孙虹孙康孙晓阳孙志嘉谭志新唐洪庆唐靖宇唐新懿田斌斌王丽娇王鹏程王琦王涛峰文杰温中伟吴青彪吴晓光吴煊羊奕伟易晗于莉于永积张国辉张林浩张显鹏张玉亮张志永赵豫斌周路平周祖英朱丹阳朱科军朱鹏朱兴华中国原子能科学研究院核数据重点实验室北京102413 中国科学院高能物理研究所北京100049 散裂中子源科学中心东莞523803 核探测与核电子学国家重点实验室北京100049 中国科学技术大学近代物理系核探测与核电子学国家重点实验室合肥230026 北京大学物理学院核物理与核技术国家重点实验室北京100871 中国工程物理研究院核物理与化学研究所绵阳621900 西北核技术研究院西安710024 中国科学院大学北京100049 中国科学技术大学工程与应用物理系合肥230026 北京航空航天大学物理学院北京100083 华能山东石岛湾核电有限公司荣成264312

中子辐射俘获反应在反应堆运行、核装置设计及核天体物理研究中起重要的作用.4πBaF_(2)探测装置有着高时间分辨能力、低中子灵敏度、高探测效率等优点,适合开展中子辐射俘获反应截面数据的测量.中国原子能科学研究院核数据重点实验室... 详细信息

中子辐射俘获反应在反应堆运行、核装置设计及核天体物理研究中起重要的作用.4πBaF_(2)探测装置有着高时间分辨能力、低中子灵敏度、高探测效率等优点,适合开展中子辐射俘获反应截面数据的测量.中国原子能科学研究院核数据重点实验室建立了伽马全吸收装置(Gamma total absorption facility,GTAF),该装置用28块六棱BaF_(2)晶体和12块五棱BaF_(2)晶体构成了外径25 cm,内径10 cm的球壳,覆盖了95.2%的立体角.利用GTAF在中国散裂中子源Back-n束线上,测量了197Au(n,γ)的反应截面数据.测量数据通过能量筛选、PSD方法、晶体多重性筛选进行了初步本底扣除,随后结合对^(nat)C及空样品的测量数据对本底进行了分析及扣除,获得了197Au俘获反应的产额,利用SAMMY程序拟合得到了^(197)Au在1—100 e V的共振能量、中子共振宽度和伽马共振宽度参数.实验测量结果与ENDF/B-VIII.0数据库符合良好,其共振参数存在一定差异,分析原因可能与GTAF能量分辨率、Back-n的中子能谱测量精度、以及实验本底扣除方法相关,这也是下一步工作的重点.

关键词：中子辐射俘获截面共振参数白光中子源伽马全吸收装置

维普期刊数据库博看期刊

The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-li Luo Yong-Heng Zhao Gang Zhao li-Cai Deng Xiao-Wei liu Yi-Peng Jing Gang wang Hao-Tong zhang Jian-Rong Shi Xiang-qun Cui Yao-quan Chu Guo-Ping li Zhong-rui Bai Yue Wu Yan Cai shu-Yun cao Zi-huang cao Jeffrey L.Carlin hai-Yuan Chen Jian-Jun Chen Kun-Xin Chen li Chen Xue-Lei Chen Xiao-Yan Chen Ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng Jian-Ning Fu Peng Gao Xue-Fei Gong bo-Zhong Gu Yan-Xin Guo Zhan-Wen Han bo-liang He Jin-liang Hou Yong-hui Hou Wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu zhi-Ying Huo Lei Jia Fang-hua Jiang Xiang Jiang zhi-bo Jiang Ge Jin Xiao Kong Xu Kong Ya-Juan Lei Ai-hua li Chang-hua li Guang-Wei li hai-Ning li Jian li Qi li shuang li Sha-Sha li Xin-Nan li Yan li Yin-Bi li Ye-Ping li Yuan liang Chien-Cheng lin Chao liu Gen-Rong liu Guan-qun liu zhi-Gang liu Wen-zhi Lu Yu Luo Yin-Dun mao Heidi Newberg Ji-Jun Ni Zhao-Xiang Qi Yong-Jun Qi Shi-Yin Shen Huo-Ming Shi Jing song Yi-Han song Ding-Qiang Su Hong-Jun Su Zheng-Hong Tang Qing-Sheng Tao Yuan Tian Dan wang Da-Qi wang Feng-Fei wang Guo-Min wang hai wang Hong-Chi wang Jian wang Jia-Ning wang Jian-ling wang Jian-Ping wang Jun-Xian wang Lei wang Meng-Xin wang Shou-Guan wang shu-Qing wang Xia wang Ya-Nan wang You wang Yue-Fei wang You-Fen wang Peng Wei Ming-zhi Wei Hong Wu Ke-Fei Wu Xue-Bing Wu Yu-Zhong Wu Xiao-Zheng Xing ling-Zhe Xu Xin-Qi Xu Yan Xu Tai-Sheng Yan De-hua yang hai-Feng yang hui-Qin yang Ming yang Zheng-Qiu Yao Yong Yu hui Yuan hai-bo Yuan hai-long Yuan Wei-Min Yuan Chao Zhai En-Peng zhang hua-Wei zhang Jian-Nan zhang li-Pin zhang Wei zhang Yong zhang Yan-Xia zhang Zheng-Chao zhang Ming Zhao Fang Zhou Xu Zhou Jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

基于CSNS反角白光中子源的中子俘获反应截面测量技术研究

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物理学报 2021年第22期70卷 28-39页

作者：张奇玮栾广源任杰阮锡超贺国珠鲍杰孙琪黄翰雄王朝辉顾旻皓余滔解立坤陈永浩安琪白怀勇鲍煜曹平陈昊磊陈琪萍陈裕凯陈朕崔增琪樊瑞睿封常青高可庆韩长材韩子杰何泳成洪杨黄蔚玲黄锡汝季筱璐吉旭阳蒋伟江浩雨姜智杰敬罕涛康玲康明涛李波李超李嘉雯李论李强李晓李样刘荣刘树彬刘星言穆奇丽宁常军齐斌斌任智洲宋英鹏宋朝晖孙虹孙康孙晓阳孙志嘉谭志新唐洪庆唐靖宇唐新懿田斌斌王丽娇王鹏程王琦王涛峰文杰温中伟吴青彪吴晓光吴煊羊奕伟易晗于莉于永积张国辉张林浩张显鹏张玉亮张志永赵豫斌周路平周祖英朱丹阳朱科军朱鹏朱兴华中国原子能科学研究院核数据重点实验室北京102413 中国科学院高能物理研究所北京100049 散裂中子源科学中心东莞523803 核探测与核电子学国家重点实验室北京100049 中国科学技术大学近代物理系合肥230026 北京大学物理学院核物理与核技术国家重点实验室北京100871 中国工程物理研究院核物理与化学研究所绵阳621900 西北核技术研究院西安710024 中国科学院大学北京100049 中国科学技术大学工程与应用物理系合肥230026 北京航空航天大学物理学院北京100083 华能山东石岛湾核电有限公司荣成264312

中子俘获反应截面数据在核天体物理研究、先进核能开发中具有非常重要的应用,由于缺乏合适的白光中子源和探测装置,国内在keV能区(1 eV-100 keV)中子俘获反应截面的实验数据几乎是空白.中国原子能科学研究院核数据重点实验室建造了国内... 详细信息

中子俘获反应截面数据在核天体物理研究、先进核能开发中具有非常重要的应用,由于缺乏合适的白光中子源和探测装置,国内在keV能区(1 eV-100 keV)中子俘获反应截面的实验数据几乎是空白.中国原子能科学研究院核数据重点实验室建造了国内第一台γ全吸收型探测装置,由40块BaF_(2)探测器单元组成厚度为15 cm,内半径为10 cm的BaF_(2)晶体球壳,共覆盖了95.2%的立体角.利用升级后的装置在中国散裂中子源的反角白光中子源上建立了中子俘获反应截面在线测量技术.在不规则的φ30 mm中子束斑的实验条件下,完成首次197Au中子俘获反应截面的在线测量,利用加和能谱和多重数分布扣除本底,反演飞行时间谱得到keV能区197Au中子俘获反应截面的实验数据.通过与ENDF评价数据库相关数据的比较,共振峰位置能够很好地吻合,从而验证了测量装置和测量技术的可靠性,为下一步高精度截面数据的获取奠定基础.

关键词： γ全吸收型探测装置中子俘获反应截面中国散裂中子源白光中子源

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抗肿瘤药物处方审核专家共识——乳腺癌

中国药学杂志 2020年第11期55卷 961-967页

作者：杨珺于波黄红兵翟青李焕杜琼刘澍戴媛媛贺飞樊英王晨董梅刘江刘玉国徐珽黄萍张文周蒋刚曹俊岭王丽霞戴助孙言才姜明燕吕永宁卢晓阳刘茂柏梁宁生宋燕青李朋梅刘广宣郝志英姚敦武李桂茹孔树佳谢瑞祥王建华魏青贾乐川李玫孟珺曹舫陈寒杰鄢丹白在先李国辉赫捷国家癌症中心国家肿瘤临床医学研究中心中国医学科学院北京协和医学院肿瘤医院北京100021 复旦大学附属肿瘤医院上海200032 中山大学肿瘤防治中心广州510060 天津医科大学肿瘤医院天津300060 哈尔滨医科大学附属肿瘤医院哈尔滨150081 河北医科大学第四医院石家庄050000 山东省肿瘤医院济南250117 四川大学华西医院成都610041 浙江省肿瘤医院杭州310022 河南省肿瘤医院郑州450008 四川省肿瘤医院成都610047 北京中医药大学东方医院北京100078 中国中医科学院广安门医院北京100053 湖北省肿瘤医院武汉430079 安徽省肿瘤医院合肥230031 中国医科大学附属第一医院沈阳110001 华中科技大学同济医学院附属协和医院武汉430022 浙江大学附属第一医院杭州310003 福建医科大学附属协和医院福州350001 广西医科大学附属肿瘤医院南宁530021 吉林大学第一医院长春130021 中日友好医院北京100029 辽宁省肿瘤医院沈阳110042 山西省肿瘤医院太原030013 湖南省肿瘤医院长沙410013 大连医科大学附属第二医院辽宁大连116023 云南省肿瘤医院昆明650000 福建省肿瘤医院福州350014 新疆医科大学第一附属医院乌鲁木齐830011 江苏省肿瘤医院南京210009 宁夏医科大学总医院肿瘤医院银川750004 吉林省肿瘤医院长春130000 国家癌症中心国家肿瘤临床医学研究中心中国医学科学院北京协和医学院肿瘤医院深圳医院广东深圳518116 陕西省肿瘤医院西安710061 青海省人民医院西宁810007 首都医科大学附属北京世纪坛医院北京100038 内蒙古自治区肿瘤医院呼和浩特010020 上海交通大学医学院附属同仁医院上海200336

乳腺癌是我国女性人群中发病率和死亡率最高的恶性肿瘤,年新发病例约27.89万例,占女性全部恶性肿瘤发病的16.51%,位居女性恶性肿瘤发病的首位[1]。和很多恶性肿瘤一样,乳腺癌的治疗采取多学科综合治疗与个体化治疗相结合的模式,根据患... 详细信息

乳腺癌是我国女性人群中发病率和死亡率最高的恶性肿瘤,年新发病例约27.89万例,占女性全部恶性肿瘤发病的16.51%,位居女性恶性肿瘤发病的首位[1]。和很多恶性肿瘤一样,乳腺癌的治疗采取多学科综合治疗与个体化治疗相结合的模式,根据患者的身体状况、肿瘤的病理组织学类型和分子分型、侵及范围和发展趋向,采取手术、放疗、化疗、内分泌治疗和分子靶向治疗等手段。

关键词：抗肿瘤处方共识乳腺癌