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Tripartite intensive intervention for prevention of rebleeding in elderly patients with hypertensive cerebral hemorrhage

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World Journal of Clinical Cases 2021年第33期9卷 10106-10115页

作者： cai-xia li li li Jin-Feng Zhang Qi-Hong Zhang xiao-Hong Jin Guo-Juan cai Department of Critical Care Affiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Emergency Zhuji People’s Hospital of Zhejiang ProvinceZhuji 311800Zhejiang ProvinceChina

BACKGROUND Hypertensive cerebral hemorrhage(HICH)is the rupture and bleeding of vessels of the cerebral parenchyma caused by continuously elevated or violently fluctuating blood *** condition is characterized by high disability and high *** formation and resulting space-occupying effects following intracerebral hemorrhage are among the key causes of impaired neurological function and ***,minimally invasive clearance of the hematoma is undertaken for the treatment of HICH because it can effectively relieve intracranial ***,special attention should be given to the quality of medical and nursing interventions in the convalescent period after minimally invasive hematoma *** The study aim was to determine the value of intensive intervention,including doctors,nurses,and patient families,for the prevention of rebleeding in elderly patients with HICH during the first hospitalization for rehabilitation after the ictal event METHODS A total of 150 elderly HICH patients with minimally invasive hematoma evacuation in our hospital between May 2018 and May 2020 were selected and equally divided into two groups of 75 each by their planned *** control group was given conventional nursing intervention and the observation group was given tripartite intensive *** length of hospital stay,cost,complication rate,satisfaction rate,and rebleeding rate during hospitalization were *** in cerebral blood flow indicators were recorded in both *** in the National Institutes of Health Stroke Scale(NIHSS)score,quality of life index(Qli)score,and health behavior score were evaluated at the National Institutes of *** Duration of hospitalization was shorter in the in the observation group than in the control group,the hospitalization cost was less than in the control group,and the rate of rebleeding during hospitalization was lower than in the control group(all P<0.05)

关键词： Tripartite intensive intervention by doctors Nurses and patient families Hypertensive intracerebral hemorrhage Rebleeding Rehabilitation Nerve function

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Trans-arterial gene therapy for hepatocellular carcinoma in a rabbit model

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World Journal of Gastroenterology 2007年第14期13卷 2113-2117页

作者： Tao Gu cai-xia li Yan Feng Qian Wang Chun-Hai li Chuan-Fu li Department of Radiology Qilu Hospital of Shandong University Jinan 250012 Shandong Province China

AIM： To study the effect of adenovirus （Ad）-p53 gene therapy on hepatocellular carcinoma （HCC） in a rabbit model.METHODS： VX2 tumor was grown in the liver of 24rabbits. Animals were divided into four groups： group A receiving trans-arterial gene therapy （Ad-p53） only,group B receiving combined Ad-p53 therapy and transarterial embolization （lipiodol）, group C receiving transarterial chemoembolization （lipiodol ＋ mitomycin C）,control group （D） receiving sodium chloride. Tumor volume （V1） was measured by using MRI （d 13）.Interventional procedure was applied （d 14）.Tumor volume （V2） was assessed by MRT （d 21） and the mean ratio （V2/V1） was calculated. After the second MRI,specimens of the liver were abstained and examined immunohistochemically using mutant-type p53 *** positive expression was scored.RESULTS： Compared with control group （（^-x） = 3.14± 0.64）, therapeutic groups all showed a significant decrease in the tumor growth ratio （P 〈 0.05）. A slight difference was found between group A （（^-x） =2.35 ±0.59） and group B （（^-x） = 1.75 ± 0.28）（P = 0.048）. Nostatistically significant difference was observed between group B and group C （（^-x） = 2.00 ± 0.44）. The positive expression rate of mutant-type p53 was the lowest in group B and significantly different between group A and group C （P 〈 0.05）.Compared to the control subjects, groups A and C both showed a decrease in the expression of mutant-type p53, but there was no significant difference between them.CONCLUSION： Trans-arterial Ad-p53 gene therapy can reduce tumor growth of HCC in rabbit model.

关键词： liver hepatocellular carcinoma Trans-arterial chemoembolization Gene therapy

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运动员食育实践的困境与应对策略

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食品与机械 2021年第10期37卷 189-192,201页

作者：蔡利霞河南机电职业学院动力森林体育健康学院河南郑州451100

文章以国内、外食育理论和实践发展为契机,探讨当前中国运动员膳食营养管理中存在的主要问题,提出促进营养均衡管理和改善运动表现为基本导向的运动员食育实践模式,还对运动员食育实践中涉及的受众群体、食育主体、基本原则和实施策略... 详细信息

文章以国内、外食育理论和实践发展为契机,探讨当前中国运动员膳食营养管理中存在的主要问题,提出促进营养均衡管理和改善运动表现为基本导向的运动员食育实践模式,还对运动员食育实践中涉及的受众群体、食育主体、基本原则和实施策略一一作了分析。

关键词：食育运动员运动营养现实困境应对策略

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Comparison on Immune Efficacy of Avian Influenza Virus Re-5 Strain and SS Strain in Guangxi Sanhuang Chickens

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Animal Husbandry and Feed Science 2011年第5期3卷 23-25,29页

作者： LU cai-xia li Jun-cheng HE Yin-e Guangxi Agricultural College Nanning 530007 China

[ Objective] To compare immune efficacy of avian influenza virus （AIV） Re-5 strain （HSN1 subtype） and SS strain （ H9 subtype） in Guangxi Sanhuang chickens. [Method] A total of 180 Sanhuang chickens were selected from a breeding chicken farm in Guilin City of Guangxi and assigned into four groups （ n = 45）. At 145 days old, the chickens in the group I and II were respectively inoculated with AIV Re-5 strain and AIV SS strain, but they were kept in cages separately. The two control groups were not inoculated. Antibody levels were determined at 170 days old. [ Result] The level of antibodies against AIV Re-5 strain was significantly higher in the chickens of the group I and group II than in the corresponding control groups, respectively （ P 〈 0.01 ）. The level of antibodies against AIV SS strain was not significantly different between the group I and its control group or between the group II and its control group. [ Conclusion] The antibody level of chickens can be increased by the AIV Re-5 strain but not by the AIV SS strain.

关键词： Guangxi Sanhuang chickens H5 vaccine H9 vaccine Immune efficacy

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衬底温度对低功率直流磁控溅射ZnO薄膜特性的影响

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功能材料 2008年第8期39卷 1279-1282页

作者：蔡利霞马书懿李伟李锡森李勇西北师范大学物理与电子工程学院甘肃兰州730070 河南师范大学物理与信息工程学院河南新乡453007

采用低功率直流反应磁控溅射法,在Si衬底上成功制备出了具有高c轴择优取向的ZnO薄膜,利用X射线衍射仪、荧光分光光度计研究了沉积温度对ZnO薄膜微观结构及光致发光特性的影响。结果表明,合适的村底温度有利于提高ZnO薄膜结晶质量;在室... 详细信息

采用低功率直流反应磁控溅射法,在Si衬底上成功制备出了具有高c轴择优取向的ZnO薄膜,利用X射线衍射仪、荧光分光光度计研究了沉积温度对ZnO薄膜微观结构及光致发光特性的影响。结果表明,合适的村底温度有利于提高ZnO薄膜结晶质量;在室温下测量样品的光致发光谱(PL),观察到波长位于440nm左右和485nm左右的蓝色发光峰及527nm左右微弱的绿光峰,随村底温度升高,样品的PL谱中蓝光强度都明显增大,低功率溅射对其蓝光发射具有很重要的影响。综合分析得出440nm左右的蓝光发射应与Zn;有关,485nm附近的蓝先发射是由于氧空位形成的深施主能级上电子跃迁到价带顶的结果,而527nm左右的较弱的绿先发射主要来源于导带底到氧错位缺陷能级的跃迁。生长温度主要是通过改变薄膜中缺陷种类及浓度而影响着ZnO薄膜的发光特性的。

关键词： ZnO薄膜磁控溅射 X射线衍射光致发光

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稀土钇掺杂多孔硅光致发光研究

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功能材料 2008年第7期39卷 1108-1110,1114页

作者：李锡森马书懿孙小菁蔡利霞李勇西北师范大学物理与电子工程学院甘肃兰州730070

采用电化学方法在多孔硅中掺杂了稀土钇(Y)元素。用荧光分光光度计分析了样品的光致发光特性。多孔硅样品在440nm波长激发下,光致发光谱上主发光峰位于620nm,认为其来源于Si-O复合物的发光中心;多孔硅样品在390nm波长激发下,光致发光谱... 详细信息

采用电化学方法在多孔硅中掺杂了稀土钇(Y)元素。用荧光分光光度计分析了样品的光致发光特性。多孔硅样品在440nm波长激发下,光致发光谱上主发光峰位于620nm,认为其来源于Si-O复合物的发光中心;多孔硅样品在390nm波长激发下,光致发光谱上主发光峰分别位于527和576nm,并且用量子限制/发光中心模型加以解释。钇掺杂多孔硅样品的光致发光强度明显增强,并且在484nm附近出现新的发光峰。分析结果认为,这是由于钇的掺入,在多孔硅禁带中形成了新的表面能级,从而形成新的发光中心的结果。

关键词：多孔硅稀土钇掺杂光致发光

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Treatment Effects of Common Melastoma Herb on White Scour in Piglets

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Animal Husbandry and Feed Science 2011年第4期3卷 13-15页

作者： LU cai-xia li Jun-cheng QIN Jun ZHANG Min-teng LAN Tong-xing ZHOU Ru-jun Guangxi Agdcultural Collage Nanning 530007 China

[ Objective] To explore the treatment effects of common melastoma herb decoction on white scour in piglets. [ Method] Piglets suffering from white scour were orally given the common melastorna herb decoction and norfloxacin, respectively. [ Result] After the weaned piglets were gavaged medicines, the treatment effect of the common melastoma herb decoction was significantly different from that of norfloxacin （ P 〈 0.05）, and the optimal dosage of common melastoma herb decoction was 20 ml per piglet for treatment. After the weaned piglets were given medicines added in feedstuff, the treatment effect of the common melastoma herb decoction was significantly different from that of norfloxacin （P 〈 0.01 ）, and the optimum dosage of common melastoma herb decoction was 50 ml per piglet for treatment. The preventive effect of the common melastoma herb decoction was significantly different from that of the control group in 35-day＇old piglets suffering from white scour （ P 〈 0.05）, and the optimal dosage of common melastoma herb decoction was 15 ml per piglet for prophylaxis. To mix medicine in feedstuff was the preferred way for the diseased piglets having appetite. [ Cenclusion] The common melastoma herb decoction has treatment effects and preventive effects on white scour of piglets.

关键词： Common melastoma herb Prophylaxis White scour Piglets

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Cytotoxicity of anti-tumor herbal Marsdeniae tenacissimae extract on erythrocytes

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第7期18卷 597-604页

作者： Ke HAO Bing-yu CHEN Kai-qiang li Yu ZHANG cai-xia li Ying WANG Lu-xi JIANG Jiang SHEN xiang-chai GUO Wei ZHANG Meng-hua ZHU Zhen WANG Research Center of Blood Transfusion Medicine Ministry of Education Key Laboratory of Laboratory Medicine Department of Blood Transfusion Zhejiang Provincial People's Hospital People's Hospital of Hangzhou Medical College Department of Blood Transfusion Lishui People's Hospital

Marsdeniae tenacissimae extract （MTE） has been used as an adjuvant medicine for cancer therapy for a long time. Although massive studies demonstrated its considerable anti-cancer effect, there is no research on its influence on erythrocytes, which are firstly interacted with MTE in the circulation. To investigate the influence of MTE on erythrocytes, we used a flow cytometer to detect the MTE-treated alternations of morphology, calcium concentration, and reactive oxygen species （ROS） level in erythrocytes. We used hemolysis under different osmotic solutions to evaluate the fragility of erythrocytes. Data showed that MTE treatment dose-dependently increased the ratio of erythrocyte fragmentation （P〈0.001） and shrinking, and elevated the forward scatter （FSC） value （P〈0.001） and calcium accumulation （P〈0.001）. MTE induced ROS production of erythrocytes under the high glucose condition （P〈0.01） and consequently caused a rise in fragility （P〈0.05）. These results suggest that MTE induces cytotoxicity and aging in erythrocytes in a dose-dependent manner, and presents the possibility of impairment on cancer patients＇ circulating erythrocytes when MTE is used as an anti-cancer adjuvant medicine.

关键词： Marsdeniae tenacissimae extract Erythrocyte Calcium Reactive oxygen species (ROS) Fragility

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Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑life lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang li Wen‑xia Su Jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng cai Kang li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous li deposition and highly reversible li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous li+flux lithium metal battery

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高温氧化物晶体界面非稳定性研究

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无机材料学报 2000年第5期15卷 769-776页

作者：金蔚青蔡丽霞潘志雷苗宇中国科学院上海硅酸盐研究所上海200050

设计了一套模拟实验，以获得关于晶体形态和界面非稳定性的差异的可靠数据，如高温溶液生长的骸晶和枝蔓晶．这些实验是在高温实时观察装置（ＨＩＴＩＳＯＴ）内进行的．高温溶液晶体生长实验是在环形铂金丝炉圈内进行的．炉圈直径为２... 详细信息

设计了一套模拟实验，以获得关于晶体形态和界面非稳定性的差异的可靠数据，如高温溶液生长的骸晶和枝蔓晶．这些实验是在高温实时观察装置（ＨＩＴＩＳＯＴ）内进行的．高温溶液晶体生长实验是在环形铂金丝炉圈内进行的．炉圈直径为２ｍｍ．铂金丝既起加热又起支撑熔体的作用．选用ＫＮｂＯ３和Ｌｉ２Ｂ４Ｏ７的混合物进行晶体生长实验．在只存在扩散机制的快速生长过程中，会形成不同的晶体不完整性，如晶面凹坑、骸晶和枝蔓晶．采用淬火实验以分辨不同的ＫＮｂｏＯ３晶体形态，并用扫描电镜研究Ｌｉ２Ｂ４Ｏ７溶体中ＫＮｂＯ３晶体生长的形貌．在一般情况下，当晶体在气液界面附近液相区成核时，会产生晶体界面非稳定性．导致晶体形状不稳定的溶液层的厚度为６０μｍ．通过扫描电镜观察，发现晶体在这一溶液层中由多面体晶变为枝蔓晶．骸晶和枝蔓晶的各向异性反映了ＫＮｂＯ３的立方特性，也反映了界面非稳定性是沿［１１０］晶棱扩大的，［１１０］晶棱方向的分支证实了晶体生长形状的各向异性·形成界面非稳定性的临界尺寸为１０μｍ．与此相反，中持稳定的晶面形状是通过６０μｍ厚度以下的溶液内的晶体生长来实现的．晶体生长过程是由高温实时观察装置进行实时观察和记录的，并能观察到晶体固液?

关键词：高温氧化物界面非稳定性晶体生长

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