检索结果-南通市图书馆

Current Medical Science 2024年第4期44卷 692-697页

作者： Jun-feng zhang Feng-qing cai Xiu-cai zhang Qing YE Department of Laboratory Medicine Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou310052China

Objective Inflammation is involved in the development and progression of nonalcoholic fatty liver disease(NAFLD).The monocyte to high-density lipoprotein cholesterol ratio(MHR)has emerged as a marker for various inflammation-related *** aim of the present study was to investigate the association between the MHR and NAFLD in a population with childhood *** Based on hepatic ultrasound,a total of 504 children with obesity(357 with NAFLD and 147 without NAFLD)were included in the *** correlation between the MHR and NAFLD risk factors was assessed by Pearson’s and Spearman’s *** stepwise logistic regression analyses were conducted to explore the association between the MHR and the risk of *** The MHR in patients with NAFLD was significantly greater than that in patients without NAFLD[0.52(0.44-0.67)versus 0.44(0.34-0.57),P<0.001].Multivariate stepwise logistic regression analysis demonstrated that the MHR[odds ratio(OR):1.033,95%confidence interval(CI):1.015-1.051;P<0.001]was an independent predictor of NAFLD in childhood obesity patients,as were age(OR:1.205,95%CI:1.059-1.371;P=0.005],waist circumference[OR:1.037,95%CI:1.008-1.067;P=0.012],and alanine transaminase[OR:1.067,95%CI:1.045-1.089;P<0.001].Additionally,MHR quartiles showed a significant positive association with the incidence of NAFLD after adjusting for potential confounding *** The present study showed that the MHR may serve as an available and useful indicator of NAFLD in individuals with childhood obesity.

关键词： nonalcoholic fatty liver disease obesity monocyte-to-high-density lipoprotein ratio marker

Theoretical understanding of correlation between magnetic phase transition and the superconducting dome in high-Tc cuprates

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 167-173页

作者： Chen zhang cai-Xin zhang Su-Huai Wei Haiqing Lin Hui-Xiong Deng State Key Laboratory of Superlattices and Microstructures Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Beijing Computational Science Research Center Beijing 100193China

Many issues concerning the origin of high-temperature superconductivity(HTS)are still under *** example,how the magnetic order varies with doping and its relationship with the superconducting temperature(Tc);and why Tcalways peaks near the quantum critical *** this paper,taking hole-doped La_(2)CuO_(4)as a classical example,we employ the first-principles band structure and total energy calculations with Monte Carlo simulations to explore how the symmetry-breaking magnetic ground state evolves with hole doping and the origin of a dome-shaped superconductivity region in the phase *** demonstrate that the local antiferromagnetic order and doping play key roles in determining the electron-phonon coupling,thus ***,the La_(2)CuO_(4)possesses a checkerboard local antiferromagnetic ground *** the hole doping increases,Tcincreases with the enhanced electron-phonon coupling *** as the doping increases further,the strength of the antiferromagnetic interaction weakens and spin fluctuation *** the critical doping level,a magnetic phase transition occurs that reduces the local antiferromagnetism-assisted electron-phonon coupling,thus diminishing the *** superconductivity disappears in the heavily overdoped region when the ferromagnetic order *** observations could account for why cuprates have a dome-shaped superconductivity region in the phase *** study,thus,contributes to a fundamental understanding of the correlation between doping,local magnetic order,and superconductivity of HTS.

关键词： high-temperature superconductivity antiferromagnetic order electron-phonon coupling doping effect cuprates

维普期刊数据库

TSC prediction and dynamic control of BOF steelmaking with state-of-the-art machine learning and deep learning methods

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第1期31卷 174-194页

作者： Tian-yi Xie cai-dong zhang Quan-lin Zhou Zhi-qiang Tian Shuai Liu Han-jie Guo Material Technology Research Institute Hesteel GroupShijiazhuang050023HebeiChina Tangsteel Company Hesteel GroupTangshan063611HebeiChina School of Artificial Intelligence Beijing Technology and Business UniversityBeijing100048China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China

Mathematical(data-driven)models based on state-of-the-art(SOTA)machine learning and deep learning models and data collected from 12,786 heats were established to predict the values of temperature,sample,and carbon(TSC)test,including temperature of molten steel(TSC-Temp),carbon content(TSC-C)and phosphorus content(TSC-P),which made prepa-ration for eliminating the TSC *** maximize the prediction accuracy of the proposed approach,various models with different inputs were implemented and compared,and the best models were applied to the production process of a Hesteel Group steelmaking plant in China in the *** number of tabular features(hot metal information,scrap,additives,blowing practices,and preset values)was expanded,and time series(off-gas profiles and blowing practice curves)that could reflect the entire steelmaking process were introduced as ***,the latest machine learning models(LightGBM,CatBoost,TabNet,and NODE)were used to make predictions with tabular features,and the best coefficient of determination R^(2)values obtained for TSC-P,TSC-C and TSC-Temp predictions were 0.435(LightGBM),0.857(Cat-Boost)and 0.678(LightGBM),respectively,which were higher than those of classic models(backpropagation and support vector machine).Then,making predictions was performed by using SOTA time series regression models(SCINet,DLinear,Informer,and MLSTM-FCN)with original time series,SOTA image regression models(NesT,caiT,ResNeXt,and GoogLeNet)with resized time series,and the proposed Concatenate-Model and Parallel-Model with both tabular features and time *** optimization and comparisons,it was finally determined that the Concatenate-Model with MLSTM-FCN,SCINet and Informer as feature extractors performed the best,and its R^(2)values for predicting TSC-P,TSC-C and TSC-Temp reached 0.470,0.858 and 0.710,*** field test accuracies for TSC-P,TSC-C and TSC-Temp were 0.459,0.850 and 0.685,respectively.A related importance analysis was carri

关键词： BOF steelmaking In-blow prediction TSC test Machine learning Deep learning Field application

Impact of transparent exopolymer particles on the dynamics of dissolved organic carbon in the Amundsen Sea,Antarctica

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Polar Science 2024年第1期35卷 123-131页

作者： HU Ji XUE Siyou ZHAO Jun LI Dong zhang Haifeng YU Peisong zhang cai YANG Xufeng PAN Jianming Key Laboratory of Marine Ecosystem Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China College of Ocean and Earth Sciences Xiamen UniversityXiamen 361102China

The Southern Ocean is an important carbon sink pool and plays a critical role in the global carbon *** Amundsen Sea was reported to be highly productive in inshore area in the Southern *** order to investigate the influence of transparent exopolymer particles(TEP)on the behavior of dissolved organic carbon(DOC)in this region,a comprehensive study was conducted,encompassing both open water areas and highly productive *** was found that microbial heterotrophic metabolism is the primary process responsible for the production of humic-like fluorescent components in the open *** relationship between apparent oxygen utilization and the two humic-like components can be accurately described by a power-law function,with a conversion rate consistent with that observed *** presence of TEP was found to have little impact on this ***,the study revealed the accumulation of DOC at the sea surface in the Amundsen Sea Polynya,suggesting that TEP may play a critical role in this *** findings contribute to a deeper understanding of the dynamics and surface accumulation of DOC in the Amundsen Sea Polynya,and provide valuable insights into the carbon cycle in this region.

关键词： dissolved organic matter chromophoric dissolved organic matter excitation-emission matrix coupled with parallel factor analysis transparent exopolymer particles Amundsen Sea Antarctica

维普期刊数据库

Risk Factors of Enternal Nutrition Intolerance in Septic Patients:A Case-control Study

在线全文

学校读者我要写书评

暂无评论

Current Medical Science 2024年第2期44卷 328-332页

作者： Li-zhu WANG Yan XIANG Qian LI Yi-rong ZHU Jue FANG Xiao-dan LU Zhao-cai zhang Department of Nursing The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Critical Care Medicine The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Key Laboratory of the Diagnosis and Treatment for Severe Trauma and Burn of Zhejiang Province Hangzhou 310009China Zhejiang Province Clinical Research Center for Emergency and Critical Care Medicine Hangzhou 310009China

Objective:This study aimed to investigate the incidence of enteral nutrition intolerance(ENI)in patients with sepsis and explore potential risk ***:A case-control study was conducted in patients with sepsis who were receiving enteral nutrition(EN)at a tertiary hospital in *** included patients were divided into the ENI group and the non-ENI *** and multivariate analyses were performed to identify the risk factors for ***:A total of 859 patients were included in the *** them,288(33.53%)patients experienced symptoms of ENI,including diarrhea,vomiting,bloating,and gastric *** regression analysis revealed that the Acute Physiology and Chronic Health Evaluation H(APACHE H)score,thoracocentesis,and usage of cardiotonic drugs(namely,inotropes)were independent predictors of the ***:The incidence of ENI is relatively high in patients with sepsis,especially in those who have higher APACHE H scores,have undergone thoracocentesis,and have received inotropes.

关键词： sepsis enteral nutrition intolerance influencing factor

Marginal zone lymphoma with severe rashes: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第3期12卷 565-574页

作者： Si-Jun Bai Ye Geng Yi-Nan Gao cai-Xia zhang Qian Mi Chen zhang Jia-Ling Yang Si-Jie He Zhen-YingYan Jian-Xia He Department of Hematology Shanxi Provincial People’s HospitalTaiyuan 030012Shanxi ProvinceChina

BACKGROUND Marginal zone lymphoma(MZL)is an indolent subtype of non-Hodgkin lymphoma(NHL),which is rare clinically with severe rashes as the initial *** SUMMARY This study reports a case of MZL with generalized skin rashes accompanied by pruritus and purulent ***-line treatment with rituximab combined with zanubrutinib had poor ***,after switching to obinutuzumab combined with zanubrutinib,the case was alleviated,and the rashes *** For patients with advanced stage MZL not benefiting from type I anti-CD20 monoclonal antibody(mAb)combination therapy,switching to a type II anti-CD20 mAb combination regimen may be *** approach may provide a new perspective in the treatment of MZL.

关键词： Marginal zone lymphoma Mucosa-associated lymphoid tissue Extranodal marginal zone lymphoma Primary cutaneous marginal zone lymphoma Rituximab,Obinutuzumab Zanubrutinib Case report

Network pharmacology and animal experiments revealed the protective effects of Guilong Prescription(归龙方) on chronic prostatitis and its possible mechanisms

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medicine 2024年

作者： ZHU Peixuan SU Zeqi FAN Qiongyin zhang cai WANG Ting School of Chinese Medicine， Beijing University of Chinese Medicine Beijing Research Institute of Chinese Medicine， Beijing University of Chinese Medicine State Key Laboratory of Toxicology and Medical Countermeasures， Beijing Key Laboratory of Neuropsychopharmacology， Beijing Institute of Pharmacology and Toxicology

OBJECTIVE: To investigate the protective effects of Guilong prescription (归龙方， GL) on chronic prostatitis (CP) and unravel the underlying mechanisms of its pharmacological effects. METHODS: The composition of GL was determined via linear ion trap/electrostatic field orbital trap tandem high-resolution mass spectrometry， and the identified compounds were performed network pharmacological analysis to predict possible pathways of the effects of GL on CP. A CP rat model was established by carrageenan， and rats were randomly assigned into a Control group， Sham group， CP group， GL low dose (3.5 g/kg) group， GL medium dose (7 g/kg) group， and GL high dose (14 g/kg) group. Hematoxylin-eosin staining of the prostate， and prostate blood -perfusion measured by laser speckle contrast analysis were used to evaluate the efficacy of GL. Expression of intercellular cell adhesion molecule-1 (ICAM-1) and induce nitric oxide synthase (iNOS) were determined by immunohistochemistry， and the content of interferon-γ (IFN-γ)， interleukin-1β (IL-1β)， interleukin-4 (IL-4)， interleukin-10 (IL-10)， chemokine ligand 1 (CXCL1) and tumor necrosis factor-α (TNF-α) were determined by electro-chemiluminescence assays. The expression of p38 mitogen-activated protein kinase (p38 MAPK)， phosphatidylinositol 3-kinase (PI3K)， ribosome-associated complex-alpha serine/threonine-protein kinase (Akt)， nuclear factor-κ-gene binding p65 (NF-κB p65)， inhibitor of NF-κB-α (IκBα)， glycogen synthase kinase-3β (GSK-3β)， and their phosphorylated forms were tested by Western blot. RESULTS: In GL， a total of 48 compounds were identified， including 14 flavonoids， 14 alkaloids， 11 carboxylic acids， 4 lactones， 2 glycosides， 2 terpenoids and 1 aldehyde. Network pharmacological analysis suggested that the mechanism of GL may be related to PI3K-Akt signaling pathway and cytokine expression. After treatment with GL， inflammatory pathological changes in the prostate of rats were significantly improved， and blood perfusion

关键词：

日本积极老龄化媒介话语建构及中国启示--以《朝日新闻》(1984—2020)为例

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

河北学刊 2024年第3期44卷 186-192页

作者：张佩佩张彩中国传媒大学新闻学院

“积极老龄化”是全球应对人口老龄化的基本理念和政策基础。日本作为世界上老龄化程度最高的国家,在践行积极老龄化理念、建设适老化社会方面积累了较为丰富的经验。日本《朝日新闻》借助于积极老龄化媒介话语的建构,在社会动因、媒体... 详细信息

“积极老龄化”是全球应对人口老龄化的基本理念和政策基础。日本作为世界上老龄化程度最高的国家,在践行积极老龄化理念、建设适老化社会方面积累了较为丰富的经验。日本《朝日新闻》借助于积极老龄化媒介话语的建构,在社会动因、媒体环境视角及其老龄化报道等方面阐释了积极老龄化内涵,发挥了媒介赋权功能,并构建讨论空间,在一定程度上推动了社会和谐。这些经验和做法给予我们的启示是:应结合中国老龄社会特点,在积极老龄化媒介话语建构中创新报道理念,充分了解群体需求,完善信息功能;丰富报道话语,强调参与共建意识,提升群体成就感;挖掘报道价值,增强舆论引导功能,推进形象建构。

关键词：积极老龄化日本媒体媒介话语建构媒介功能

维普期刊数据库

Investigation and Mitigation of Carbon Deposition over Copper Catalyst during Electrochemical CO_(2)Reduction

在线全文

学校读者我要写书评

暂无评论

Precision Chemistry 2024年第4期2卷 151-160页

作者： Jing-Wen DuanMu Zhi-Zheng Wu Fei-Yue Gao Peng-Peng Yang Zhuang-Zhuang Niu Yu-cai zhang Li-Ping Chi Min-Rui Gao Division of Nanomaterials and Chemistry Hefei National Laboratory for Physical Sciences at the MicroscaleUniversity of Science and Technology of ChinaHefei 230026China

Copper(Cu)is considered to be the most effective catalyst for electrochemical conversion of carbon dioxide(CO_(2))into value-added hydrocarbons,but its stability still faces considerable ***,we report the poisoning effect of carbon deposition during CO_(2)reduction on the active sites of Cu electrodea critical deactivation factor that is often *** find that,*C,an intermediate toward methane formation,could desorb on the electrode surface to form carbon *** reveal a strong correlation between the formation of methane and the carbon deposition,and the reaction conditions favoring methane production result in more carbon *** deposited carbon blocks the active sites and consequently causes rapid deterioration of the catalytic *** further demonstrate that the carbon deposition can be mitigated by increasing the roughness of the electrode and increasing the pH of the *** work offers a new guidance for designing more stable catalysts for CO_(2)reduction.

关键词： carbon deposition roughness in situ spectrum CO_(2)electroreduction copper catalyst

Understanding of Five Grains for YANG:a way to straighten Asians’dietary structure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Health 2024年第3期6卷 18-19页

作者： Jing-Chao Ma cai-Jie zhang Wen-Li Zhao Ye Zhao* Intelligent Imaging College He UniversityShenyang 110163China.2 Liver CenterSaga University HospitalSaga University 849-8501Japan.3 Department of Public HealthInternational CollegeKrirk UniversityBangkok 10220Thailand.

According to the general opinion,grains should occupy the largest amount of human food each day,but this grain-based eating habit does not allow human life to be *** are high in carbohydrates and five commonly recognized plant hormones,namely auxin,gibberellin,cytokinin,abscisic acid,and *** in-depth analysis of ancient books,it was found that five grains for support:support is a restriction,and it means the essence,which means that grains should be eaten less,and it is the essence of the least daily *** correctly understand the Chinese dietary concept of"five grains for support"is the basis for improving Asian dietary health and promoting Asian human health.

关键词： Grains Hormones Carbohydrates Eating habits