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comparison between the therapeutic effects of differentiated and undifferentiated Wharton’s jelly mesenchymal stem cells in rats with streptozotocin-induced diabetes

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World Journal of Stem cells 2020年第2期12卷 139-151页

作者： chen-Yuan hsiao Tien-Hua chen Ben-Shian Huang Po-Han chen c.eng-hsi su Jia-Fwu Shyu Pei-Jiun Tsai Graduate Institute of Medical Sciences National Defense Medical CenterTaipei 114Taiwan Department of surgery Landseed International HospitalTaoyuan 324Taiwan Institute of Anatomy and cell Biology School of MedicineNational Yang Ming UniversityTaipei 112Taiwan Trauma center Department of SurgeryVeterans General HospitalTaipei 112Taiwan Division of General surgery Department of SurgeryVeterans General HospitalTaipei 112Taiwan Department of Obstetrics and Gynecology Veterans General HospitalTaipei 112Taiwan Department of surgery Cheng Hsin General HospitalTaipei 112Taiwan Department of Biology and Anatomy National Defense Medical CenterTaipei 114Taiwan Department of critical care Medicine Veterans General HospitalTaipei 112Taiwan

BAcKGROUND Despite the availability of current therapies,including oral antidiabetic drugs and insulin,for controlling the symptoms caused by high blood glucose,it is difficult to cure diabetes mellitus,especially type 1 diabetes *** cell therapies using mesenchymal stem cells(MScs)may be a promising ***,the therapeutic mechanisms by which MScs exert their effects,such as whether they can differentiate into insulin-producing cells (IPcs) beforetransplantation, are *** this study, we used three types of differentiation media over 10 d to generateIPcs from human Wharton’s jelly MScs (hWJ-MScs). We further transplantedthe undifferentiated hWJ-MScs and differentiated IPcs derived from them intothe portal vein of rats with streptozotocin-induced diabetes, and recorded thephysiological and pathological *** fluorescent staining and c-peptide enzyme-linked immunoassay, we wereable to successfully induce the differentiation of hWJ-MScs into *** of both IPcs derived from hWJ-MScs and undifferentiated hWJMScshad the therapeutic effect of ameliorating blood glucose levels andimproving intraperitoneal glucose tolerance tests. The transplanted IPcs homedto the pancreas and functionally survived for at least 8 wk after transplantation,whereas the undifferentiated hWJ-MScs were able to improve the insulitis andameliorate the serum inflammatory cytokine in streptozotocin-induced *** IPcs can significantly improve blood glucose levels in diabetic ratsdue to the continuous secretion of insulin by transplanted cells that survive in theislets of diabetic rats. Transplantation of undifferentiated hWJ-MScs cansignificantly improve insulitis and re-balance the inflammatory condition indiabetic rats with only a slight improvement in blood glucose levels.

关键词： Human Wharton’s jelly mesenchymal stem cell Insulin-producing cells Diabetes mellitus Differentiation Regeneration therapy Anti-inflammatory

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基于Retinex的自适应水域图像去雾算法

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应用科技 2024年第4期51卷 62-68页

作者：苏丽张丽君哈尔滨工程大学智能科学与工程学院黑龙江哈尔滨150001

针对利用Retinex理论对水域雾天图像去雾时出现去雾不彻底、色彩失真等问题,提出一种基于Retinex的自适应水域图像去雾算法,通过分析水域雾天图像特征,提出水域雾气浓度划分标准,实现自适应去雾。将水域雾天图像由RGB颜色空间转到hsi颜... 详细信息

针对利用Retinex理论对水域雾天图像去雾时出现去雾不彻底、色彩失真等问题,提出一种基于Retinex的自适应水域图像去雾算法,通过分析水域雾天图像特征,提出水域雾气浓度划分标准,实现自适应去雾。将水域雾天图像由RGB颜色空间转到hsi颜色空间,对亮度(Intensity,I)分量进行拉伸变换以调节亮度平衡,再用改进的单尺度Retinex(singal scale Retinex,SSR)算法对I分量进行增强处理,初步提高图像清晰度;将增强处理后的图像转换回RGB颜色空间进行自适应伽马变换增强,进一步提高图像的清晰度及对比度;利用hsi颜色空间进行图像饱和度补偿及其他操作实现对水域雾天图像的色彩恢复。实验结果表明,该算法能有效进行自适应水域雾天图像去雾,色彩恢复真实,可得到细节清晰的高质量去雾图像。

关键词： Retinex 雾气浓度划分自适应去雾 hsi颜色空间引导滤波自适应伽马变换饱和度补偿色彩恢复

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台湾地区的农村社区土地重划--以云林县古坑乡水碓社区为例

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国际城市规划 2016年第6期31卷 40-44页

作者：苏南何肇喜台湾云林科技大学营建系台湾云林科技大学创意生活设计系

台湾地区农村社区土地重划的目的在于缩短城乡发展差距,改善农村生活环境,进而推动社区发展及各方面建设。本文以云林县古坑乡水碓农村社区土地重划为例,介绍云林县落实农村社区土地重划的示范计划(2009—2014)。农村社区土地重划的内... 详细信息

台湾地区农村社区土地重划的目的在于缩短城乡发展差距,改善农村生活环境,进而推动社区发展及各方面建设。本文以云林县古坑乡水碓农村社区土地重划为例,介绍云林县落实农村社区土地重划的示范计划(2009—2014)。农村社区土地重划的内容包括社区绿化美化,道路兴建拓宽,建设社区活动中心、停车场、公园,以及兴修其他公共设施。社区土地重划及相关建设对农村的环境改善有诸多帮助。

关键词：台湾农村土地重划水碓社区

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HIV-infected Female Sex Workers High Risk Behavior and Attitude changes in Kaiyuan city, Yunnan Province, china

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Biomedical and Environmental Sciences 2014年第6期27卷 444-452页

作者： DING Guo Wei hsi Jenny H LIU Hui Xin su Ying Ying WANG Jun Jie BAI Jun WANG Gui Xiang WANG Hai Bo DONG Rui Ling WANG Ning National center for AIDS/STD control and Prevention Chinese Center for Disease Control and Prevention Kaiyuan city center for Disease control and Prevention chinese center for Disease control and Prevention Shenzhen International Travel Healthcare center

Objective To investigate the attitude and sexual behavior status and change among HIV positive female workers in entertainment sites in Kaiyuan city, Yunnan province, china. The key information should be applied in the integrated intervention program in future. Methods A cohort survey among HIV positive female workers was conducted during 12 months, between 2010 and 2012. All the risk sexual behavior and attitude were collected for assessment for the potential secondary transmission to sexual partners. Results Of 99 HIV positive women who sell sex in Kaiyuan city, 99 participated in the survey at baseline, 80, 80, 75, and 75 at 3-, 6-, 9-, and 12-month follow-ups. The percentage of participants who reported consistently used condoms in the last one month ranged between 94.5% and 95.5%. The client volume in the last one month, income per sex and age group were significant related with non-insistent condom use with their clients. conclusion It was suggested that integrated intervention program package should include 100 percent condom use promotion for the HIV positive FSW with all sexual partners, and also, include socially support involved.

关键词： HIV-infected Female sex workers Sexual behavior change

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NON-PENETRATING ABDOMINAL INJURIES WITH RUPTURE OF GASTRO-INTESTINAL TRAcT: WITH REPORT OF TWO cASES

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中华医学杂志(英文版) 1949年第8期67卷 446-446页

作者： HUNG-hsi su P. c. TUNG Department of surgery Medical College National Central University Nanking

The gastro-intestinal tract fromfthe stomach down to the rectum may be ruptured at any point by non-penetrating violence, the small iptestine probably being ruptured more frequently than the stomach and the Jarge intestine. Accidents in eivilian life from the automobiles and heavy industries as well as in modern warfare from underwater blasts (1) produce innumerable intra-abdominal injuries. In these cases early diagnosis is of paramount importance, and their mortality can be greatly rpduced if operation is performed at the easrliest possible moment. The following two cases may serve as illustrations.

关键词： ABDOMEN DIGESTIVE SYSTEM

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A Statistical Features-based color Difference classification Method 25th

A Statistical Features-based Color Difference Classification...

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第25届中国控制与决策会议

作者： su Feng-wu Jiang Mai School of Telecommunication Heilongjiang Institute of Science and Technology Shenyang Institute of Automation Chinese Academy of Sciences

ISBN: (纸本)9781467355339

This paper presents a method for color difference based on Histogram statistical values. First, the color image in RGB color space is converted to hsi color space, median filter was selected for image preprocessing. Then, the ceramic samples hsi Histogram statistical of each channel was calculated respectively. Take the Histogram statistical as the color difference classification character value. For real time requirement, using minimum distance classifier as classification basis. compared with the S, I channel, the results showed that adopted the H channel Histogram statistical value as feature vector has higher accuracy for ceramic tile color difference classification.

关键词： ceramic tile color difference classification hsi color model Histogram statistical

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cost-effectiveness analysis of population-based screening of hepatocellular carcinoma: comparing ultrasonography with two-stage screening

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World Journal of Gastroenterology 2016年第12期22卷 3460-3470页

作者： Ming-Jeng Kuo hsiu-hsi chen chi-Ling chen Jean ching-Yuan Fann Sam Li-Sheng chen Sherry Yueh-hsia chiu Yu-Min Lin chao-Sheng Liao Hung-chuen chang Yueh-Shih Lin Amy Ming-Fang Yen Department of Hepatogastroenterology Tainan Municipal Hospital Tainan 701 Taiwan Graduate Institute of Epidemiology and Preventive Medicine College of Public Health National Taiwan University Taipei 100 Taiwan Graduate Institute of clinical Medicine College of Medicine and Graduate Institute of Epidemiology and Preventive Medicine College of Public Health National Taiwan University Taipei 100 Taiwan Department of Health Industry Management School of Healthcare Management Kainan University Taoyuan 338 Taiwan School of Oral Hygiene College of Oral Medicine Taipei Medical University Taipei 110 Taiwan Department and Graduate Institute of Health care Management Chang Gung University Taoyuan 333 Taiwan Division of Gastroenterology Department of Internal Medicine Shin-Kong Wu Ho-Su Memorial Hospital Taipei 111 Taiwan angder Health clinics Taipei 111 Taiwan

AIM: To assess the cost-effectiveness of two populationbased hepatocellular carcinoma(Hcc) screening programs, two-stage biomarker-ultrasound method and mass screening using abdominal ultrasonography(AUS).METHODS: In this study, we applied a Markov decision model with a societal perspective and a lifetime horizon for the general population-based cohorts in an area with high Hcc incidence, such as Taiwan. The accuracy of biomarkers and ultrasonography was estimated from published meta-analyses. The costs of surveillance, diagnosis, and treatment were based on a combination of published literature, Medicare payments, and medical expenditure at the National Taiwan University Hospital. The main outcome measure was cost per lifeyear gained with a 3% annual discount rate. REsuLTS: The results show that the mass screening using AUS was associated with an incremental costeffectiveness ratio of USD39825 per life-year gained, whereas two-stage screening was associated with an incremental cost-effectiveness ratio of USD49733 per life-year gained, as compared with no screening. Screening programs with an initial screening age of 50 years old and biennial screening interval were the most cost-effective. These findings were sensitive to the costs of screening tools and the specificity of biomarker ***: Mass screening using AUS is more cost effective than two-stage biomarker-ultrasound screening. The most optimal strategy is an initial screening age at 50 years old with a 2-year inter-screening interval.

关键词： Two-stage biomarker-ultrasound screening One-stage abdominal ultrasonography screening Markov model cost-effectiveness Sensitivity analysis Age

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单幅图像中值暗通道先验去雾的改进算法

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光电子．激光 2015年第8期26卷 1611-1617页

作者：黄素霞莆田学院机电工程学院福建莆田351100

为解决传统基于暗通道先验(DcP)的单幅去雾算法在景物边界处出现的白边现象及高计算复杂度,在中值DcP(MDcP)法的基础上提出一种改进算法。首先通过判断RGB三颜色通道的最小值与中值暗原色的差值绝对值的大小判断DcP法或MDcP法是否成立:... 详细信息

为解决传统基于暗通道先验(DcP)的单幅去雾算法在景物边界处出现的白边现象及高计算复杂度,在中值DcP(MDcP)法的基础上提出一种改进算法。首先通过判断RGB三颜色通道的最小值与中值暗原色的差值绝对值的大小判断DcP法或MDcP法是否成立:当DcP法成立时,取较大窗口的暗原色值作为最终的暗原色值;当DcP法不成立而MDcP法成立时,取两种窗口中中值暗原色值较小的值作为最终的暗原色值;当DcP法和MDcP法都不成立时,取较小窗口的中值暗原色值作为最终的暗原色值。然后在hsi色彩空间保留色调分量不变,仅对强度分量运用修改的暗原色值进行去雾。最后,对饱和度分量进行颜色补偿。本文算法无需图像后期修补。实验结果表明了本文改进算法的可行性和有效性。

关键词：单幅图像去雾暗通道先验(DcP) 中值DcP(MDcP) hsi色彩空间

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《西游记》余国藩英译本中诗词全译的策略及意义

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外语研究 2009年第2期26卷 82-86页

作者：苏艳华中师范大学外国语学院翻译研究中心湖北武汉430079 南开大学外国语学院天津300071

诗词全译是《西游记》余国藩英译本最突出的特点和成就之一,体现了译者坚定的可译论思想,也是他在反思中国文学的翻译现状后选择异化翻译策略的结果。本文认为,诗词全译是余译本的整体价值评判的关键参数:首先,诗词全译直接关涉译者对... 详细信息

诗词全译是《西游记》余国藩英译本最突出的特点和成就之一,体现了译者坚定的可译论思想,也是他在反思中国文学的翻译现状后选择异化翻译策略的结果。本文认为,诗词全译是余译本的整体价值评判的关键参数:首先,诗词全译直接关涉译者对小说性质的定位和对主题的认识,其结果是将译本建构为一个蕴涵宗教思想和寓言架构的多重文本;其次,诗词全译完整再现了中国传统章回体小说韵散相间的叙事特点;第三,诗词全译体现了译者对作者身份的确认和对作品语言风格的再现。

关键词：《西游记》英译诗词可译性异化寓言韵散相间

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金鱼和鳊鱼卵球受精的细胞学研究

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实验生物学报 1960年第Z1期 29-46页

作者：朱洗陈兆熙王幽兰中国科学院实难生物研究所中国科学院实难生物研究所上海

前言一、金鱼的受精1.生体观察(1)受精膜的形成(2)胚盘的形成(3)卵的扫卜泄 4造形物质的集中 2.受精的袖胞学研究 (l)即将受精的卵球 (2)精虫入卵后的变化

关键词：卵球焦和精孔胚盘朱洗细胞学生物学

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