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Runx2 regulates peripheral nerve regeneration to promote Schwann cell migration and re-myelination

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Neural Regeneration Research 2024年第7期19卷 1575-1583页

作者： Rong hu Xinpeng Dun Lolita Singh Matthew c.Banton School of Traditional chinese Medicine Department of Traditional Chinese MedicineNanfang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina The co-innovation center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Faculty of Health University of PlymouthPlymouthUK

Runx2 is a major regulator of osteoblast differentiation and function;however,the role of Runx2 in peripheral nerve repair is unclea ***,we analyzed Runx2expression following injury and found that it was specifically up-regulated in Schwann ***,using Schwann cell-specific Runx2 knocko ut mice,we studied peripheral nerve development and regeneration and found that multiple steps in the regeneration process following sciatic nerve injury were *** observed in Runx2 knoc kout mice include increased prolife ration of Schwann cells,impaired Schwann cell migration and axonal regrowth,reduced re-myelination of axo ns,and a block in macrophage clearance in the late stage of *** together,our findings indicate that Runx2 is a key regulator of Schwann cell plasticity,and therefore peripheral nerve ***,our study shows that Runx2 plays a major role in Schwann cell migration,re-myelination,and peripheral nerve functional recovery following injury.

关键词： macrophage clearance migration peripheral nerve injury regeneration re-myelination Runx2 Schwann cells

An improved pulse coupled neural networks model for semantic IoT

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Digital communications and Networks 2024年第3期10卷 557-567页

作者： Rong Ma Zhen Zhang Yide Ma Xiping hu Edith c.H.Ngai Victor c.M.Leung School of Information Sc.ence and engineering Lanzhou UniversityLanzhou 730000China School of Medical Technology Beijing Institute of TechnologyBeijing100081China Department of Electrical and Electronic.engineer The University of Hong KongHong Kong 999077China college of computer Sc.ence and Software engineering Shenzhen UniversityShenzhen 518060China Department of Electrical and computer engineering the University of British ColumbiaVancouverBC V6T 1Z4Canada

In recent years,the Internet of Things(IoT)has gradually developed applications such as collecting sensory data and building intelligent services,which has led to an explosion in mobile data ***,with the rapid development of artificial intelligence,semantic communication has attracted great attention as a new communication ***,for IoT devices,however,processing image information effic.ently in real time is an essential task for the rapid transmission of semantic *** the increase of model parameters in deep learning methods,the model inference time in sensor devices continues to *** contrast,the Pulse coupled Neural Network(PcNN)has fewer parameters,making it more suitable for processing real-time scene tasks such as image segmentation,which lays the foundation for real-time,effective,and accurate image ***,the parameters of PcNN are determined by trial and error,which limits its *** overcome this limitation,an Improved Pulse coupled Neural Networks(IPcNN)model is proposed in this *** IPcNN constructs the connection between the static properties of the input image and the dynamic properties of the neurons,and all its parameters are set adaptively,which avoids the inconvenience of manual setting in traditional methods and improves the adaptability of parameters to different types of *** segmentation results demonstrate the validity and effic.ency of the proposed self-adaptive parameter setting method of IPcNN on the gray images and natural images from the Matlab and Berkeley Segmentation *** IPcNN method achieves a better segmentation result without training,providing a new solution for the real-time transmission of image semantic information.

关键词： Internet of things(IoT) Semantic information Real-time application Improved pulse coupled neural network Image segmentation

Mechanistic insight into cr(Ⅵ)retention by Si-containing ferrihydrite

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Journal of environmental Sc.ences 2024年第5期139卷 217-225页

作者： Ying hu Qiang Xue Honghan c.en huaming Guo Kenneth c.carroll Song Wang MOE Key Laboratory of Groundwater circulation and environmental Evolution School of Water Resources and EnvironmentChina University of Geosciences(Beijing)Beijing 100083China Beijing Key Laboratory of Water Resources and environmental engineering School of Water Resources and EnvironmentChina University of GeosciencesBeijing 100083China State Key Laboratory of Biogeology and environmental Geology China University of GeosciencesBeijing 100083China Plant&environmental Sc.ence New Mexico State UniversityNM 88003USA Institute of Theoretical chemistry College of ChemistryJilin UniversityChangchun 130023China

Hexavalent chromium[cr(Ⅵ)]causes serious harm to the environment due to its high toxicity,solubility,and ***(Fh)are the main adsorbent and trapping agent of cr(Ⅵ)in soils and aquifers,and they usually coexist with silicate(Si),forming Si-containing ferrihydrite(Si-Fh)***,the mechanism of cr(Ⅵ)retention by Si-Fh mixtures is poorly *** this study,the behaviors and mechanisms of cr(Ⅵ)adsorption onto Si-Fh with different Si/Fe molar ratios was *** electron microscope,Fourier transform infrared spectroscopy,X-ray diffraction,X-ray photoelectron spectroscopy,and other techniques were used to characterize Si-Fh and cr(Ⅵ)-loading of *** results show that specific surface area of Si-Fh increases gradually with increasing Si/Fe ratios,but cr(Ⅵ)adsorption on Si-Fh decreases with increasing Si/Fe *** is because with an increase in Si/Fe molar ratio,the point of zero charge of Si-Fh gradually decreases and electrostatic repulsion between Si-Fh and cr(Ⅵ)***,the complexation of cr(Ⅵ)is enhanced due to the increase in adsorbed hydroxyl(A-OH-)on Si-Fh with increasing Si/Fe molar ratio,which partly counteracts the effect of the electrostatic ***,the increase in the electrostatic repulsion has a greater impact on adsorption than the additional complexation with *** functional theory calculation further supports this observation,showing the increases in electron variation of bonding atoms and reaction energies of inner spherical complexes with the increase in Si/Fe ratio.

关键词： Hexavalent chromium Ferrihydrite Si/Fe ratio cr(Ⅵ)Adsorption

Doped low-density parity-check codes

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Digital communications and Networks 2024年第1期10卷 217-226页

作者： Yong Li Rui Liu Xianlong Jiao Youqiang hu Zhen Luo Francis c.M.Lau college of computer Sc.ence Chongqing UniversityChongqing400044China School of Automation Chongqing UniversityChongqing400044China college of Electronic and Information engineering Southwest UniversityChongqing400715China Future Wireless Networks and IoT Focusing Area Department of Electronic and Information EngineeringHong Kong Polytechnic UniversityHong KongChina

In this paper,we propose a doping approach to lower the error floor of Low-Density Parity-check(LDPc)*** doping component is a short block code in which the information bits are selected from the coded bits of the dominant trapping sets of the LDPc ***,an algorithm for selecting the information bits of the short code is proposed,and a specific two-stage decoding algorithm is *** results demonstrate that the proposed doped LDPc code achieves up to 2.0 dB gain compared with the original LDPc code at a frame error rate of 10^(-6)Furthermore,the proposed design can lower the error floor of original LDPc codes.

关键词： LDPc codes Doped LDPc codes Tanner graph Quadratic residue codes Trapping sets

Modulating p-type doping of two-dimensional material palladium diselenide

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Nano Research 2024年第4期17卷 3232-3244页

作者： Jiali Yang Yu Liu en-Yang Wang Jinbo Pang Shirong huang Thomas Gemming Jinshun Bi Alicja Bachmatiuk Hao Jia Shu-Xian hu chongyun Jiang Hong Liu Gianaurelio cuniberti Weijia Zhou Mark H Rümmeli Institute for Advanced Interdisciplinary Research(iAIR) University of JinanJinan 250022China Institute for Materials chemistry Leibniz Institute for Solid State and Materials Research Dresden(IFW Dresden)20 Helmholtz StrasseDresden 01069Germany State Key Lab of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China college of energy Soochow Institute for Energy and Materials Innovations Soochow UniversitySuzhou 215006China Key Laboratory of Advanced carbon Materials and Wearable energy Technologies of Jiangsu Province Soochow UniversitySuzhou 215006China School of Integrated circuits University of Chinese Academy of SciencesBeijing 101408China Institute of Microelectronics of Tianjin Binhai New Area Tianjin 300451China Institute of Microelectronics Chinese Academy of SciencesBeijing 100029China Lukasiewicz Research Network PORT Polish Center for Technology DevelopmentStablowicka 147Wroclaw 54-066Poland School of Mathematics and Physics University of Science and Technology BeijingBeijing 100083China college of electronic information and optical engineering Nankai UniversityTianjin 300350China centre of Polymer and carbon Materials Polish Academy of SciencesM.Curie Sklodowskiej 34Zabrze 41-819Poland center for energy and environmental Technologies VŠB-Technical University of Ostrava17.Listopadu 15Ostrava 70833Czech Republic State Key Laboratory of crystal Materials Center of Bio&Micro/Nano Functional MaterialsShandong UniversityJinan 250100China Dresden center for computational Materials Sc.ence Technische Universität DresdenDresden 01062Germany Dresden center for Intelligent Materials(GcL DcIM) Technische Universität DresdenDresden 01062Germany Institute for Materials Sc.ence and Max Bergmann center of Biomaterials Technische Universität DresdenDresden 01069Germany center for Advancing Electronics Dresden Technische Universität DresdenDresden 01069Germany

The van der Waals heterostructures have evolved as novel materials for complementing the Si-based semiconductor ***-10 noble metal dichalcogenides(e.g.,PtS_(2),PtSe_(2),PdS_(2),and PdSe_(2))have been listed into two-dimensional(2D)materials toolkit to assemble van der Waals *** them,PdSe_(2) demonstrates advantages of high stability in air,high mobility,and wide tunable ***,the regulation of p-type doping of PdSe_(2) remains unsolved problem prior to fabricating p–n junction as a fundamental platform of semiconductor ***,a quantitative method for the controllable doping of PdSe_(2) is yet to be *** this study,the doping level of PdSe_(2) was correlated with the concentration of Lewis acids,for example,Sncl_(4),used for *** the transfer characteristics,the threshold voltage(the gate voltage corresponding to the minimum drain current)increased after Sncl_(4) soaking ***_(2) transistors were soaked in Sncl_(4) solutions with five different *** threshold voltages from the as-obtained transfer curves were extracted for linear fitting to the threshold voltage versus doping concentration correlation *** study provides in-depth insights into the controllable p-type doping of PdSe_(2).It may also push forward the research of the regulation of conductivity behaviors of 2D materials.

关键词： two-dimensional(2D)materials Lewis acid treatment p-type doping field-effect transistors transfer characteristic

Dramatic Difference Between cu_(20)H_(8)and cu_(20)H_(9)clusters in catalysis

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ccS chemistry 2024年第6期6卷 1581-1590页

作者： chun-Yu Liu Tong-Yu Liu Zong-Jie Guan Song Wang Yuan-Yuan Dong Feng hu De-en Jiang Quan-Ming Wang Department of chemistry Engineering Research Center of Advanced Rare Earth Materials(Ministry of Education)Tsinghua UniversityBeijing 100084 Jiangsu engineering Research centre for Digital Textile Inkjet Printing Key Laboratory of Eco-Textile Jiangnan UniversityMinistry of EducationWuxiJiangsu 214122 Department of chemical and Biomolecular engineering Vanderbilt UniversityNashvilleTennessee 37235 Department of chemistry Vanderbilt UniversityNashvilleTennessee 37235 college of chemistry and chemical engineering Hunan UniversityChangsha 410082 Hefei National Research center for Physical Sc.ences at the Microscale School of Chemistry and Materials ScienceUniversity of Science and Technology of ChinaHefeiAnhui 230026

Sensitivity to structure and composition is very challenging to establish in nanocatalysis due to inadequate definition of structures that are very close in *** synthesized a pair of atomically precise copper clusters that are very close in composition,[cu_(20)H_(9)(Tf-dpf)_(10)]·BF4(cu_(20)H_(9))and[cu_(20)H_(8)(Tf-dpf)_(10)]·(BF_(4))_(2)(cu_(20)H_(8)),by using a pyridyl-functionalized flexible amidinate ligand,N,N′-di(5-trifluoromethyl-2-pyridyl)*** one-hydride difference in their composition leads to significant variation in geometric and electronic structures and,consequently,distinctly different optical and catalytic ***_(20)H_(8)exhibits 25 times higher catalytic activity than cu_(20)H_(9)(96.7%vs 3.7%in yield)in the selective hydrogenation of anα,β-unsaturated aldehyde(cinnamaldehyde)to saturated aldehyde(3-phenylpropanal).Electrospray ionization mass spectrometry combined with density functional theory calculations reveal that the greater ease of dissociation of one Tf-dpf ligand compared to cu_(20)H_(8)is the key to its higher *** work demonstrates a clear case of structure and composition sensitivity in nanocatalysis and that one hydride,out of∼330 atoms in the nanoclusters,can make a huge difference in the catalytic *** insights will be useful in the design and synthesis of atomically precise nanocatalysts.

关键词： copper cluster hydride amidinate ligand structural transformation hydrogenation catalysis

Two-photon polymerization lithography for imaging optics

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International Journal of Extreme Manufacturing 2024年第4期6卷 21-60页

作者： Hao Wang c.eng-Feng Pan chi Li Kishan S Menghrajani Markus A Schmidt Aoling Li Fu Fan Yu Zhou Wang Zhang Hongtao Wang Parvathi Nair Suseela Nair John You en chan Tomohiro Mori Yueqiang hu Guangwei hu Stefan A Maier Haoran Ren huigao Duan Joel K W Yang college of Mechanical and Vehicle engineering Hunan UniversityChangsha 410082People's Republic of China engineering Product Development Singapore University of Technology and DesignSingapore 487372Singapore Greater Bay Area Institute for Innovation Hunan UniversityGuangzhou 511300People's Republic of China Department of Electrical and computer engineering National University of Singapore4 Engineering Drive 3Singapore 117576Singapore School of Physics and Astronomy Faculty of ScienceMonash UniversityMelbourneVictoria 3800Australia Leibniz Institute of Photonic Technology 07745 JenaGermany Abbe center of Photonics and Faculty of Physics FSU Jena07745 JenaGermany Otto Schott Institute of Material Research FSU Jena07745 JenaGermany Institute of Materials Research and engineering A*STAR(Agency for Science Technology and Research)Singapore 138634Singapore Industrial Technology center of Wakayama Prefecture Wakayama 6496261Japan School of Electrical and Electronic.engineering Nanyang Technological UniversitySingapore639798Singapore Department of Physics Imperial College LondonLondon SW72AZUnited Kingdom

Optical imaging systems have greatly extended human visual capabilities,enabling the observation and understanding of diverse *** technologies span a broad spectrum of wavelengths from x-ray to radio frequencies and impact research activities and our daily *** glass lenses are fabricated through a series of complex processes,while polymers offer versatility and ease of ***,modern applications often require complex lens assemblies,driving the need for miniaturization and advanced designs with micro-and nanoscale features to surpass the capabilities of traditional fabrication ***-dimensional(3D)printing,or additive manufacturing,presents a solution to these challenges with benefits of rapid prototyping,customized geometries,and effic.ent production,particularly suited for miniaturized optical imaging *** 3D printing methods have demonstrated advantages over traditional counterparts,yet challenges remain in achieving nanoscale ***-photon polymerization lithography(TPL),a nanoscale 3D printing technique,enables the fabrication of intricate structures beyond the optical diffraction limit via the nonlinear process of two-photon absorption within liquid *** offers unprecedented abilities,***-free fabrication,micro-and nanoscale capabilities,and rapid prototyping of almost arbitrary complex 3D *** this review,we emphasize the importance of the criteria for optical performance evaluation of imaging devices,discuss material properties relevant to TPL,fabrication techniques,and highlight the application of TPL in optical *** the first panoramic review on this topic,it will equip researchers with foundational knowledge and recent advancements of TPL for imaging optics,promoting a deeper understanding of the *** leveraging on its high-resolution capability,extensive material range,and true 3D processing,alongside advances in materials,fabrication,and design,we en

关键词： two-photon polymerization lithography 3D printing additive manufacturing imaging optics and nanophotonics

Mapping out the reaction network of humin formation at the initial stage of fructose dehydration in water

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Green energy & environment 2024年第6期9卷 1016-1026页

作者： Xing Fu Yexin hu Ping hu hui Li Shuguang Xu Liangfang Zhu changwei hu Key Laboratory of Green chemistry and Technology Ministry of EducationCollege of ChemistrySichuan UniversityChengduSichuan610064China State Key Laboratory of Southwestern chinese Medicine Resources Innovative Institute of Chinese Medicine and PharmacyChengdu University of Traditional Chinese MedicineChengduSichuan611137China

The formation of humins hampers the large-scale production of 5-hydroxymethylfurfural(HMF)in ***,a detailed reaction network of humin formation at the initial stage of fructose-to-HMF dehydration in water is delineated by combined experimental,spectroscopic,and theoretical *** bimolecular reaction pathways to build up soluble humins are *** is,the intermolecular etherification of β-furanose at room temperature initiates the c12 path,whereas the c-c cleavage of a-furanose at 130-150℃ leads to c11 path,and that of open-chain fructose at 180℃ to c11' *** successive intramolecular dehydrations and condensations of the as-formed bimolecular intermediates lead to three types of soluble *** show that the c12 path could be restrained by using Hcl or Alcl_(3) catalyst,and both the c12 and c110 paths could be effectively inhibited by adding THF as a co-solvent or accelerating heating rate via microwave heating.

关键词： carbohydrates 5-hydroxymethylfurfural Reaction network Soluble humins Tautomer

Theoretical and experimental study of a bi-stable piezoelectric.energy harvester under hybrid galloping and band-limited random excitations

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Applied Mathematics and Mechanics(english Edition) 2024年第3期45卷 461-478页

作者： Haitao LI Tianyu ZHenG Weiyang QIN Ruilan TIAN hu DING J.c.JI Liqun c.en Department of engineering Mechanics North University of ChinaTaiyuan 030051China Department of engineering Mechanics Northwestern Polytechnical UniversityXi'an 710072China Department of engineering Mechanics Shijiazhuang Tiedao UniversityShijiazhuang 050043China Shanghai Key Laboratory of Mechanics in energy engineering Shanghai Frontier Science Center of MechnoinformaticsShanghai Institute of Applied Mathematics and MechanicsSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai 200072China School of Mechanical and Mechatronic.engineering University of Technology SydneyNew South Wales 2007Australia

In the practical environment,it is very common for the simultaneous occurrence of base excitation and *** the combined energy of vibration and wind with a single energy harvesting structure is *** this purpose,the effects of the wind speed and random excitation level are investigated with the stochastic averaging method(SAM)based on the energy *** results of the analytical prediction are verified with the Monte-carlo method(McM).The numerical simulation shows that the introduction of wind can reduce the critical excitation level for triggering an inter-well jump and make a bi-stable energy harvester(BEH)realize the performance enhancement for a weak base ***,as the strength of the wind increases to a particular level,the influence of the random base excitation on the dynamic responses is weakened,and the system exhibits a periodic galloping response.A comparison between a BEH and a linear energy harvester(LEH)indicates that the BEH demonstrates inferior performance for high-speed *** experiments are conducted to investigate the validity of the theoretical prediction and numerical *** experimental findings also show that strong random excitation is favorable for the BEH in the range of low wind ***,as the speed of the incoming wind is up to a particular level,the disadvantage of the BEH becomes clear and evident.

关键词： bi-stability inter-well response galloping band-limited random