检索结果-南通市图书馆

Preclinical and clinical evidence of the association of colibactinproducing Escherichia coli with anxiety and depression in colon cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第21期30卷 2817-2826页

作者： Fabien Rondepierre maëva meynier Johan Gagniere Vincent deneuvy Anissa deneuvy Gwenaelle Roche Elodie Baudu Bruno Pereira Richard Bonnet Nicolas Barnich Frédéric Antonio carvalho denis Pezet mathilde Bonnet Isabelle Jalenques Service de Psychiatrie de l’Adulte A et Psychologie médicale CHU Clermont-FerrandClermont-Ferrand 63000France m2iSH UMR 1071INSERMUniversity of Clermont AuvergneINRAE USC 1382Clermont-Ferrand 63001France NeuroDol UMR 1107INSERMUniversity of Clermont AuvergneClermont-Ferrand 63001France department of Digestive Surgery CHU de Clermont-FerrandClermont-Ferrand 63001France Biostatistics Unit Department of Clinical Research and InnovationCHU Clermont-FerrandClermont-Ferrand 63000France department of Bacteriology CHU de Clermont-FerrandClermont-Ferrand 63001France Universitéclermont Auvergne INPCNRSClermont Auvergne Institut PascalClermont-Ferrand 63000France

BAcKGROUND The association between the intestinal microbiota and psychiatric disorders is becoming increasingly *** gut microbiota contributes to colorectal carcinogenesis(cRc),as demonstrated with colibactin-producing Escherichia coli(coPEc).AIm To evaluate the association between coPEc prevalence and anxiety-and depressive-like behaviors with both preclinical and clinical *** Patients followed after a cRc surgery and for whom the prevalence of coPEc has been investigated underwent a psychiatric *** were compared according to the coPEc *** parallel c57BL6/J wild type mice and mice with a cRc susceptibility were chronically infected with a coPEc *** behavior was assessed using the Elevated Plus maze test,the Forced Swimming Test and the Behavior recognition system PhenoTyper®.RESULTS In a limited cohort,all patients with coPEc colonization presented with psychiatric disorders several years before cancer diagnosis,whereas only one patient(17%)without coPEc *** result was confirmed in c57BL6/J wildtype mice and in a cRc susceptibility mouse model(adenomatous polyposis colimultiple intestinal neoplasia/+).mice exhibited a significant increase in anxiety-and depressive-like behaviors after chronic infection with a coPEc *** This finding provides the first evidence that coPEc infection can induce microbiota-gut-brain axis disturbances in addition to its procarcinogenic properties.

关键词： colorectal cancer colibactin Escherichia coli colibactin-producing Escherichia coli Inflammation Anxiety depression Behavior

STcF conceptual design report (Volume 1): Physics & detector

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of physics 2024年第1期19卷 1-154页

作者： m.Achasov X.c.Ai L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.m.cai H.cai J.J.cao Q.H.cao X.cao Z.cao Q.chang K.T.chao D.Y.chen H.chen H.X.chen J.F.chen K.chen L.L.chen P.chen S.L.chen S.m.chen S.chen S.P.chen W.chen X.chen X.F.chen X.R.chen Y.chen Y.Q.chen H.Y.cheng J.cheng S.cheng T.G.cheng J.P.Dai L.Y.Dai X.c.Dai D.dedovich A.denig I.denisenko J.m.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.m.Duan D.Epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich c.Q.Feng X.Feng Y.T.Feng J.L.Fu J.Gao Y.N.Gao P.S.Ge c.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.c.Gui A.Q.Guo F.K.Guo J.c.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han m.Han X.Q.Hao J.B.He S.Q.He X.G.He Y.L.He Z.B.He Z.X.Heng B.L.Hou T.J.Hou Y.R.Hou c.Y.Hu H.m.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.c.Hu J.Hua G.S.Huang J.S.Huang m.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.B.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.B.Jiang J.Jiang S.Z.Jiang J.B.Jiao Z.Jiao H.J.Jing X.L.Kang X.S.Kang B.c.Ke m.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev c.H.Li c.Li D.Y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.J.Li H.L.Li J.m.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.J.Li H.Liang J.H.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao c.X.Lin D.X.Lin X.S.Lin B.J.Liu c.W.Liu D.Liu F.Liu G.m.Liu H.B.Liu J.Liu J.J.Liu J.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.B.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long c.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo T.Luo X.F.Luo Y.H.Luo H.J.Lyu X.R.Lyu J.P.ma P.ma Y.ma Y.m.ma F.maas S.malde D.matvienko Z.X.meng R.mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian c.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin T.L.Qiu J.Rademacker c.F.Redmer H.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia cAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom central china Normal University Wuhan 430079China central South University Changsha 410083China china University of Geosciences Wuhan 430074China china University of mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STcF)is an electron–positron collider proposed by the chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STcF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPcII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STcF project in china is under development with an extensive R&D *** document presents the physics opportunities at the STcF,describes conceptual designs of the STcF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STcF detector conceptual design

A-site ordered state in manganites with perovskite-like structure based on optimally doped compounds Ln0.70Ba0.30mnO3（Ln=Pr,Nd）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2019年第11期37卷 1242-1249页

作者： S.V.Trukhanov va Khomchenko D.V.Karpinsky m.V.Silibin A.V.Trukhanov L.S.Lobanovsky H.Szymczak c.E.Botez I.O.Troyanchuk National University of Science and Technology mISiS 119049 MoscowLeninsky Av.4Russia South Ural State University 454080 ChelyabinskLenin Av.76Russia Scientific-Practical materials Research centre of NASB 220072 MinskBelarus cFisUc Department of PhysicsUniversity of Coimbra3004-516 CoimbraPortugal National Research University of Electronic Technology"mIET 124498 ZelenogradMoscowRussia Institute for Bionic Technologies and Engineering I.M.Sechenov First Moscow State Medical University2-4 Bolshaya Pirogovskaya St.119991 MoscowRussia Institute of Physics Polish Academy of Sciences02-668 WarsawPoland The University of Texas at El Paso El PasoTX 79968-0515USA

In this paper,we report on the crystal structure and magnetic properties of the nano structured Baordered phases of rare-earth manganites obtained from the optimally doped solid solutions Ln0.70Ba0.30mnO3(Ln=Pr,Nd).The materials were studied by X-ray diffraction,scanning electron microscopy,energy dispersive spectroscopy and SQUID-magnetometry *** is found that states with different degrees of cation ordering in the A-sublattice of the ABO3 perovskite can be obtained by employing special conditions of chemical *** particular,reduction of the parent compounds results in the formation of a nanocomposite containing ferrimagnetic anion-deficient ordered phase *** of the composite does not change an average size of the nanocrystallites,but drastically alters their phase composition to stabilize ferromagnetic stoichiometric ordered phase LnBamn2O6 and ferromagnetic superstoichiometric disordered phase Ln0.90Ba0.10mnO3+δ.It is shown that the magnetic properties of the materials are determined by the joint action of chemical(cation ordering)and external(surface tension)pressures.

关键词： Ionic order magnetic transition Perovskite manganite Rare earths

A new strategy for corrosion protection of porous stainless steel using polypyrrole films

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of materials Science & Technology 2020年第2期37卷 85-95页

作者： c.Garcia-cabezon c.Garcia-Hernandez m.L.Rodriguez-mendez F.martin-Pedrosa materials Engineering E.I.I.Universidad de Valladolid47011 ValladolidSpain UvaSENS E.I.I.Universidad de Valladolid47011 ValladolidSpain

In this work,a method to improve the protection against corrosion of porous sintered stainless steel is *** is based on the electrodeposition of polypyrrole(PPy)layers doped with a large size counterion such as dodecylbenzenesulphonic acid(DBSA),a conducting polymer with high corrosion resistance and good *** efficacy of PPy coating depends on the adequate adhesion between the metal substrate and the coating *** protection against corrosion has been tested using 316 L stainless steel(SS)powder sintered at different conditions to evaluate the effect of the sintering atmosphere(nitrogen and vacuum)and cooling rates(furnace and water)on corrosion resistance,while wrought 316 L SS has been used as reference *** addition,two electrochemical deposition techniques have been tested to select the most *** circuit potential evolution,anodic polarization measurements and electrochemical impedance spectra have been used to evaluate corrosion protection in phosphate buffer saline *** has been evidenced that a more homogeneous and stable coating was obtained in the case of porous stainless *** corrosion potential shifted to nobler values and the anodic polarization branch became more *** porous samples have a good passivation performance with a lower stable passive current density and a higher breakdown *** transfer electronic resistance and the impedance module increase more than one order of ***,the porosity of sintered stainless steel is seen as an advantage for the improvement of the adherence of the PPy *** best corrosion protection is found for samples sintered in nitrogen and water-cooled.

关键词： Stainless steel Powder metallurgy Protection corrosion Electrodeposited films Polymer coatings

Silk-ELR co-recombinamer covered stents obtained by electrospinning

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2019年第1期6卷 21-28页

作者： m.Putzu F.causa manuel Parente Israel Gonza´lez de Torre J.c.Rodriguez-cabello P.A.Netti Dipartimento di Ingegneria chimica dei Materiali e della Produzione Industriale(DICMAPI)University“Federico II”Piazzale Tecchio 8080125 NaplesItaly Interdisciplinary Research centre on Biomaterials(cRIB) University of Naples Federico IIPiazzale Tecchio 8080125 NapoliItaly center for Advanced Biomaterials for Health care@cRIB Istituto Italiano di TecnologiaLargo Barsanti e Matteucci 5380125 NapoliItaly conic vascular via Carlo Maderno 236901 LuganoSwitzerland Technical Proteins NanoBioTechnology S.L. Edificio CTTAPaseo de Belen9A47011 ValladolidSpain Networking Research center on Bioengineering Biomaterials and Nanomedicine(CIBER-BBN)ValladolidSpain Bioforge Lab University of ValladolidEdificio LUCIAPaseo de Belen1947011 ValladolidSpain

In the field of tissue engineering the choice of materials is of great importance given the possibility to use biocompatible polymers produced by means of biotechnology.A large number of synthetic and natural materials have been used to this purpose and processed into scaffolds using Electrospinning *** materials that could be used for the fabrication of scaffold and degradable membranes,natural polymers such as collagen,elastin or fibroin offer the possibility to design structures strictly similar to the extracellular matrix(Ecm).Biotechnology and genetic engineering made possible the advent of a new class of biopolymers called protein-based *** example is represented by the silk-elastin-proteins that combine the elasticity and resilience of elastin with the high tensile strength of silk-fibroin and display engineered bioactive *** this work,we use electrospinning technique to produce a fibrous scaffold made of the corecombinamer *** fibres have been characterized from the morphological point of *** and morphology have been explored using Scanning Electron microscopy.A thorough study regarding the influence of Voltage,flow rate and distance have been carried out to determine the appropriate parameters to obtain the fibrous mats without defects and with a good distribution of *** has also been in vitro *** the first time we use the co-recombinamer Silk-ELR for the fabrication of a 2.5 angioplasty balloon *** structure could be useful as a coated scaffold for the regeneration of intima layer of vessels.

关键词： electrospinning silk elastin-like-recombinamers tissue engineering

Improvements in tribological and anticorrosion performance of porous Ti–6Al–4V via PEO coating

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Friction 2021年第5期9卷 1303-1318页

作者： c.Garcia-cabezón m.L.Rodríguez-méndez V.AmigóBorrás R.Bayón c.Salvo-comino c.Garcia-Hernandez F.martin-Pedrosa materials Engineering E.I.I.Universidad de ValladolidValladolid 47011Spain BioecoUva Research Institute Universidad de ValladolidValladolid 47011Spain Group UvaSENS Escuela de Ingenierías IndustrialesUniversidad de ValladolidValladolid 47011Spain Instituto de Tecnología de materials Univesitat Politécnica de ValenciaValencia 46022Spain Tribology Unit Fundación IK4-TeknikerEibar 20600Spain

medical implants manufactured using biomaterial Ti–6Al–4V exhibit some *** higher elastic modulus than that of natural bone can cause stress shielding *** can be avoided using Ti–6Al–4V with pores in the implant ***,poor corrosion and tribocorrosion behaviors are yielded because of the large area exposed to the *** mitigate both issues,coating technologies can be *** plasma electrolytic oxidation(PEO)process is a cost‐effective process that has been used successfully in nonporous Ti *** this study,two PEO coatings with different amounts of ca/P are ***,reports regarding their application in porous materials are *** effects of PEO treatments on corrosion and tribocorrosion in Ti–6Al–4V powder metallurgy are analyzed *** porous materials provide an efficient surface for PEO coatings,as demonstrated via scanning electron microscopy(SEm)and atomic force microscopy(AFm),and the porosity of the substrates improved the adherence of the *** corrosion resistance measured via electrochemical impedance spectroscopy confirmed the beneficial effect of the coatings,particularly for long exposure *** lower roughness,small pore size,and more compact film observed in the PEO–ca/P sample resulted in favorable tribological and corrosion properties.

关键词： Ti‐based alloys corrosion tribocorrosion surface modification

mechanical properties of 65mn chiral structure with three ligaments

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Acta mechanica Sinica 2019年第1期35卷 88-98,I0003页

作者： X.W.Su D.m.Zhu c.Zheng m.m.Tomovic School of Technology Beijing Forestry UniversityBeijing 100083China School of mechanical Engineering University of Science and Technology BeijingBeijing 100083 China Batten college of Engineering and Technology Old Dominion University Norfolk VA 23529 USA

chiral honeycomb structures have been developed in recent years, showing excellent mechanical properties, including in-plane deformation and out-of-plane bearing and vibration isolation. In this study, the 65mn chiral structure with three ligaments was modeled and analyzed using the finite element (FE) method. The effects of the dimensionless ligament length and dimensionless ligament thickness on the in-plane equivalent elastic modulus, equivalent Poisson's ratio, and out-of-plane shear modulus were studied. The numerical results indicate that increase of the dimensionless ligament length leads to decrease of the equivalent elastic modulus and increase of the equivalePoisson's ratio, whereas the out-of-plane equivalent shear modulus decreases. The results also indicate that increase of the dimensionless ligament thickness leads to in crease of the equivalent elastic modulus, whereas the equivalent Poisson's ratio remains nearly unchanged and the out-of-plane equivalent shear modulus shows a linear in crease. The numerical results are verified by comparis on with published experime ntal data. These results will provide a reference for the application of chiral structures with three ligaments in the aerospace field.

关键词： chiral structure with three ligaments mechanical properties Finite elemern method

First extensive and cost-effective quality check of crisis maps: presentation of assessment parameters and results

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2013年第S02期6卷 50-66页

作者： D.carrion c.corbane m.Broglia m.Pesaresi Politecnico di milano DIIARSurveyingMilanoItaly European commission Joint Research CentreInstitute for the Protection and Security of the CitizenIspra(VA)Italy

The digital representation of disaster situations into maps,mainly based on remotely sensed observations,is becoming a widely used instrument for emergency *** of maps are being produced all over the world and big attention is paid by international institutions,such as the World Bank,the United Nations and the European commission to these *** quality of crisis maps is a crucial element to ensure effectiveness in the disaster response chain,but it is often neglected with respect to the need for a rapid *** this paper a sample of crisis maps produced between 2005 and 2010 by world leader providers has been evaluated through around 40 parameters assessed by visual analysis and extracted from the validation protocol designed at the Joint Research centre(JRc)of the European *** maps turned out to be in most cases clearly readable,but some gaps and inconsistencies have been singled out,due to the lack of international standard *** results are analysed in detail and some remarks are presented.

关键词： emergency maps quality assessment readability metadata cartographic standards

Impact of ozonation on disinfection byproducts formation from phenylalanine during chlorination

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第10期144卷 199-211页

作者： Sinong Huang Hongwei Liu Kunming Wei Liang Zhang Xiaoyan ma Qingsong Li Xueyan Li Andrea m.Dietrich college of civil Engineering Zhejiang Key Laboratory of Civil Engineering Structures&Disaster Prevention and Mitigation TechnologyZhejiang University of TechnologyHangzhou 310023China Water Resources and Environmental Institute Xiamen University of TechnologyXiamen 361005China School of Environmental Science and Engineering Suzhou University of Science and TechnologySuzhou 215009China civil and Environmental Engineering Virginia Polytechnic Institute and State UniversityBlackburgVA 24061USA

As a strong oxidizing agent,ozone is used in some water treatment facilities for disinfection,taste and odor control,and removal of organic ***(Phe)was used as the target amino acid to comprehensively investigate variability of disinfection byproducts(DBPs)formation during chlorine disinfection and residual chlorine conditions subsequent to *** results showed that subsequent to ozonation,the typical regulated and unregulated DBPs formation potential(DBPsFP),including trichloromethane(Tcm),dichloroacetonitrile(DcAN),chloral hydrate(cH),dichloroacetic acid(DcAA),trichloroacetic acid(TcAA),and trichloroacetamide(TcAcAm)increased substantially,by 2.4,3.3,5.6,1.2,2.5,and 6.0 times,respectively,compared with only *** also significantly increased the DBPs yield under a 2 day simulated residual chlorine condition that mimicked the water distribution *** formations followed pseudo first order *** formation rates of DBPs in the first 6 hr were higher for Tcm(0.214 hr^(−1)),DcAN(0.244 hr^(−1)),cH(0.105 hr^(−1)),TcAcAm(0.234 hr^(−1)),DcAA(0.375 hr^(−1))and TcAA(0.190 hr^(−1))than *** peak DBPsFP of Tcm,DcAN,cH,TcAcAm,DcAA,and TcAA were obtained when that ozonation time was set at 5–15 *** times>30 min increased the mineralization of Phe and decreased the formation of DBPs upon *** bromine ion(Br^(−1))concentration increased production of bromine-DBPs and decreased chlorine-DBPs formation by 59.3%–92.2%.Higher ozone dosages and slight alkaline favored to reduce DBP formation and *** ozonation conditions should be optimized for all application purposes including DBPs reduction.

关键词： Ozone Amino acids chlorination Disinfection by-products