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The Teodorescu Operator in clifford Analysis

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chinese Annals of Mathematics,Series B 2012年第4期33卷 625-640页

作者： f.BRAcKX H.De ScHEPPER M.E. LUNA-ELIZARRARS M.SHAPIRO clifford Research Group Faculty of Engineering and Architecture Ghent University Belgium Instituto Politcnico Nacional Mexico city Mexico

Euclidean clifford analysis is a higher dimensional function theory centred around monogenic.functions, i.e., null solutions to a first order vector valued rotation in- variant differential operator called the Dirac operator. More recently, Hermitian clifford analysis has emerged as a new branch, offering yet a refinement of the Euclidean case; it focuses on the simultaneous null solutions, called Hermitian monogenic.functions, to two Hermitian Dirac operators and which are invariant under the action of the unitary group. In Euclidean clifford analysis, the Teodorescu operator is the right inverse of the Dirac operator __0. In this paper, Teodorescu operators for the Hermitian Dirac operators c9~_ and 0_~, are constructed. Moreover, the structure of the Euclidean and Hermitian Teodor- escu operators is revealed by analyzing the more subtle behaviour of their components. finally, the obtained inversion relations are still refined for the differential operators is- suing from the Euclidean and Hermitian Dirac operators by splitting the clifford algebra product into its dot and wedge parts. Their relationship with several complex variables theory is discussed.

关键词： clifford analysis Teodorescu operator Dirac operator

Anti-inflammatory activity of the leaf extacts of Gendarussa vulgaris Nees

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Asian Pac.fic Journal of Tropical Biomedicine 2011年第2期1卷 147-149页

作者： TK Mohamed Saleem AK Azeem c Dilip c Sankar NV Prasanth R Duraisami Al Shifa college of Pharmacy Poonthavanam P.OKizhatturPerinthalmannaMalappuram dist Kerala Nandha college of Pharmacy

Objective:To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris(***) ***:*** Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers,sores,inflammation, dyspepsia,healing of wounds,*** present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro and in vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation(HRBc) method and in vivo method was estimated on the carrageenan induced paw ***:Both the methods showed significant anti-inflammatory property of the different extracts tested. conclusions:The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium.

关键词： Gendarussa vulgaris Anti-inflamation HRBc carrageenan

Ileal profile of non-starch polysaccharides and oligosaccharides in response to exogenous enzymes in broiler chickens offered wheat-or maize-based diets under subclinical necrotic enteritis challenge

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Animal Nutrition 2022年第3期10卷 207-215页

作者： Eunjoo Kim Amy f.Moss Natalie K.Morgan Kosar Gharib-Naseri Peter Ader Mingan choct School of Environmental and Rural Science University of New EnglandArmidaleNSW2351Australia BASf SE 68623LampertheimGermany

The present study evaluated the impacts of fibre-degrading enzymes on the profiles of non-starch polysaccharides(NSP)and oligosaccharides(OS)in the ileum of broiler chickens offered wheat-or maize-based diets under subclinical necrotic enteritis(NE)challenge.A 224 factorial arrangement of treatments was *** were the following:NE challenge,no or yes;diet type,wheat-or maizebased;and supplemental enzymes,control(no enzyme),family 10 xylanase(XYN10),family 11 xylanase(XYN11)or b-mannanase(MAN).Birds in the challenged group were inoculated with Eimeria on d 9 and clostridium perfringens on d 14 and 15.A 3-way interaction(P=0.047)occurred on overall(d 0 to 16)weight *** NE was present,all the supplemental enzymes increased weight gain in birds fed the wheat-based diet;whereas in those fed the maize-based diet supplemental XYN10 and XYN11 decreased weight *** NE was absent,birds fed the wheat-based diet supplemented with XYN10 or MAN presented increased weight gain compared to non-supplemented birds,but no improvements with enzyme addition were observed in birds fed the maize-based diet.A 3-way interaction(P=0.002)was observed on insoluble NSP level in the *** NE was absent,all the supplemental enzymes reduced the ileal level of insoluble NSP,regardless of diet *** the challenged birds,supplementing XYN10 and MAN reduced insoluble NSP level in the ileum,but only in birds fed the wheat-based *** soluble NSP level was reduced by supplemental XYN11 and MAN,but only in birds fed the wheatbased diet,resulting in a 2-way diet typeenzyme interaction(Pffered the wheat-based diet supplemented with ***,supplementation of NSP-degrading enzymes to the wheat-based diet enhanced bird performance regardless of NE challenge,with XYN11 significantly increasing oligosaccharide ***,enzyme addition did not improve growth performance in birds fed maize-based diet

关键词： Broiler chicken Non-starch polysaccharide Subclinical necrotic enteritis Oligosaccharide

Anti-HIV-1 Activities of 4 Telomerase Restrictors

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Wuhan University Journal of Natural Sciences 2007年第6期12卷 1113-1117页

作者： YU Xin WANG Jinghui de Giuli Morghen c Radaelli A Zanotto c Beggio p college of Pharmacy Wuhan University Wuhan 430072 Hubei China Medical School Huangshi Institute of Technology Huangshi 435003 Hubei China Laboratory of Molecular Virology Department of Medical Pharmacology University of Milan Via Vanvitelli 32 20129 Milano Italy

MTT cell Proliferation Assay was used to optimize the concentration of Telomerase Restrictors（TRs） with minimum toxicity to the selected cells. fAcSort flow cytometer and Innotest P24 HIV（Human immtmodeficiency Virus） antigen mAb ELISA Kit were used to investigate the anti-HIV-1 activities of TRs. The results showed that TRs had low cytotoxicity to the PBMc （Peripheral Blood mononuclear cells） and cEM/GfP if the concentration of TRs was at 50μmol/L or below, and the supernatant from PBMc pretreated with SHIV and TR1-001 /TR1-002 could not infect the PBMc, while can infect the c8166 with reduced infectivity, which suggested that the TRs may be one of the novel resources for screening anti-HIV-1 agents.

关键词： telomerase telomerase restrictor HIV anti-HIV Agents Screening

非酒精脂肪性肝炎男性患者血清中肺炎衣原体IgA高阳性率

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世界核心医学期刊文摘（胃肠病学分册） 2005年第11期1卷 5-6页

作者： Bolukbas f.f. Bolukbas c. Zeyrek f. 陈瑜 Y. mah. 4 sok. A. Apt. Kat. 2 D. 3 63100 Yenisehir/Sanliurfa TurkeyDr.

The aim of this study was to investigate if there was any relationship between nonalcoholic steatohepatitis and the rate of chlamydia pneumoniae seropositivity in a male population. fifteen men with nonalcoholic steatohepatitis and 20 healthy men were enrolled in the study. The seropositivity rate of chlamydia pneumoniae immunoglobulin A in the nonalcoholic steatohepatitis and control groups was 53.3 and 5% , respectively. The rate of chlamydia pneumoniae immunoglobulin A positivity was significantly higher in the nonalcoholic steatohepatitis group than the controls (P = 0.002), while such a difference did not occ-ur for chlamydia pneumoniae immunoglobulin G positivity (P >0.05). There is an association between nonalcoholic steatohepatitis and persistent chlamydia pneumoniae infection as a probable causative or triggering agent. These findings suggest that further studies are necessary to clarify this association.

关键词：脂肪性肝炎 IgA 肺炎衣原体男性人群始动因素持续性 IgG

A cell-Based Smoothed finite Element Method for Modal Analysis of Non-Woven fabrics

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computers, Materials & continua 2021年第6期67卷 2765-2795页

作者： Nguyen T.Quyen N.Dourado A.J.P.Gomes f.B.N.ferreira c2T—centro de ciência e Tecnologia Têxtil Departamento de Engenharia TêxtilUniversidade do MinhoCampus de AzurémGuimarães4804-533Portugal cMEMS-UMinho Departamento de Engenharia MecânicaUniversidade do MinhoCampus de AzurémGuimarães4804-533Portugal Department of computer Science Universidade da Beira InteriorConvento de Sto.AntónioCovilhã6201-001Portugal Instituto de Telecomunicações R.Marquês deÁvila e BolamaCovilhã6201-001Portugal

The combination of a 4-node quadrilateral mixed interpolation of tensorial components element(MITc4)and the cell-based smoothed finite element method(c.fEM)was formulated and implemented in this work for the analysis of free vibration and unidirectional buckling of shell *** formulation was applied to numerous numerical examples of non-woven *** c.fEM schemes do not require coordinate transformation,spurious modes and numerical instabilities are prevented using bilinear quadrilateral element subdivided into two,three and four smoothing *** improvement of the original c.fEM formulation was made regarding the calculation of outward unit normal vectors,which allowed to remove the integral operator in the strain smoothing *** procedure conducted both to the simplification of the developed formulation and the reduction of computational cost.A wide range of values for the thickness-to-length ratio and edge boundary conditions were *** developed numerical model proved to overcome the shear locking phenomenon with success,revealing both reduced implementation effort and computational cost in comparison to the conventional fEM *** cell-based strain smoothing technique used in this work yields accurate results and generally attains higher convergence rate in energy at low computational cost.

关键词： Mindlin-Reissner theory of plates shear-locking gradient/strain smoothing technique non-woven fabric

Oxidative stress modulation in hepatitis c virus infected cells

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World Journal of Hepatology 2015年第29期7卷 2880-2889页

作者： Sonia A Lozano-Sepulveda Owen L Bryan-Marrugo carlos cordova-fletes Maria c Gutierrez-Ruiz Ana M Rivas-Estilla Department of Biochemistry and Molecular Medicine School of MedicineUniversidad Autonoma de Nuevo LeonMonterreyNuevo Leon 64460Mexico Department of Health Sciences Biological Sciences and Health DivisionSchool of Biological SciencesUniversidad Autonoma Metropolitana

Hepatitis c virus(HcV) replication is associated with the endoplasmic reticulum, where the virus can induce cellular stress. Oxidative cell damage plays an important role in HcV physiopathology. Oxidative stress is triggered when the concentration of oxygen species in the extracellular or intracellular environment exceeds antioxidant defenses. cells are protected and modulate oxidative stress through the interplay of intracellular antioxidant agents, mainly glutathione system(GSH) and thioredoxin; and antioxidant enzyme systems such as superoxide dismutase, catalase, GSH peroxidase, and heme oxygenase-1. Also, the use of natural and synthetic antioxidants(vitamin c and E, N-acetylcysteine, glycyrrhizin, polyenylphosphatidyl choline, mitoquinone, quercetin, S-adenosylmethionine and silymarin) has already shown promising results as co-adjuvants in HcV therapy. Despite all the available information, it is not known how different agents with antiviral activity can interfere with the modulation of the cell redox state induced by HcV and decrease viral replication. This review describes an evidence-based consensus on molecular mechanisms involved in HcV replication and their relationship with cell damage induced by oxidative stress generated by the virus itself and cell antiviral machinery. It also describes some molecules that modify the levels of oxidative stress in HcV-infected cells.

关键词： Hepatitis c virus Oxidative stress Reactiveoxygen species Vitamin E Antioxidants Glycyrrhizin S-adenosylmethionine N-acetylcysteine Silymarin

Acne on Pigmented Skin: Epidemiological, clinical and Therapeutic.features in Dermatology in Benin

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Journal of cosmetics, Dermatological Sciences and Applications 2019年第4期9卷 305-312页

作者： B. Dégboé c. Koudoukpo N. Agbéssi N. Elégbédé-Adégbitè f. Akpadjan H. Adégbidi f. Atadokpèdé Service of Dermatology and Venerology National Teaching Hospital HKM of Cotonou Faculty of Health Sciences University of Abomey-Calavi Abomey-Calavi Benin Service of Dermatology and Venerology Department Teaching Hospital of Borgou-Alibori Faculty of Medicine University of Parakou Parakou Benin

Purpose: The aim of this work was to describe the epidemiological, clinical and therapeutic.features of pigmented skin acne in Benin. Methods: This was a prospective, cross-sectional and analytical study conducted in the dermatology departments of the Borgou-Alibori Departmental Teaching Hospital and the National Teaching Hospital Hubert Koutoukou Maga from January 2017 to December 2018, which has included black-skinned patients who were diagnosed with acne and gave their free and informed consent. The EcLA score was used for clinical evaluation of the severity of the acne. Results: We collected 129 patients including 35 men and 94 women. The median age of the patient was 24.6 years ± 8.5 years. The median age of onset was 17.9 years ± 7.6 years. The main triggering of worsening factors was inadequate self-medication (53.5%), excoriation (48.1%), certain foods (34.9%) and lightening cosmetic (32.5%). Most patients had inflammatory (51.9%) or comedonal (31.8%) acne associated with post-inflammatory hyperpigmentations (70.5%) and excoriated lesions (31%). In the majority of cases, acne was moderate in women (52.1%) and severe in men (62.8%) with p = 9 × 10-3. The lesions were electively seated in the face (95.3%), mainly on the forehead and cheeks. Active cosmetics (76.7%), retinoids (58.9%), oral antibiotics (55.8%), and benzoyl peroxide (48.9%) were the most commonly used therapeutic classes. conclusion: The majority of young and adult women consulted for predominant inflammatory acne on the forehead and cheeks, moderate in woman and severe in men in Benin. The therapeutic arsenal consisted mainly of active cosmetics, retinoids, antibiotics and benzoyl peroxide.

关键词： Inflammatory Acne Adult Acne Active cosmetic Pigmented Skin Benin

Late Quaternary sinistral slip rate along the Altyn Tagh fault and its structural transformation model

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Science china Earth Sciences 2005年第3期48卷 384-397页

作者： P. Tapponnier J. Van Der Woerd f. J. Ryerson A.S. Meriaux Laboratoire de Tectonique Institut de Physique du Globe de Paris FranceLaboratoire de Tectonique Institut de Physique du Globe de Paris FranceIGPP Lawrence Livermore Laboratory Livermore CA 94550 USALaboratoire de Tectonique Institut de Physique du Globe de Paris France

Based on technical processing of high-resolution SPOT images and aerophotos, detailed mapping of offset landforms in combination with field examination and displacement measurement, and dating of offset geomorphic surfaces by using carbon fourteen (14c), cos- mogenic nuclides (10Be+26Al) and thermoluminescence (TL) methods, the Holocene sinistral slip rates on different segments of the Altyn Tagh fault (ATf) are obtained. The slip rates reach 17.5 ±2 mm/a on the central and western segments west of Aksay Town, 11±3.5 mm/a on the Subei-Shibaocheng segment, 4.8±1.0 mm/a on the Sulehe segment and only 2.2±0.2 mm/a on the Kuantanshan segment, an easternmost segment of the ATf. The sudden change points for loss of sinistral slip rates are located at the Subei, Shibaocheng and Shulehe triple junctions where NW-trending active thrust faults splay from the ATf and propagate southeastward. Slip vector analyses indicate that the loss of the sinistral slip rates from west to east across a triple junction has structurally transformed into local crustal shortening perpendicular to the active thrust faults and strong uplifting of the thrust sheets to form the NW-trending Danghe Nanshan, Daxueshan and Qilianshan Ranges. Therefore, the eastward extrusion of the northern Qing- hai-Tibetan Plateau is limited and this is in accord with “the imbricated thrusting transforma- tion-limited extrusion model”.

关键词： Altyn Tagh fault, sinistral strike-slip rate, structural transformation, extrusion tectonics.