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Morphology, Morphogenesis and Production of Tanzânia Grass, Sub.itted to Either Fixed or Variab.e Resting Period

American Journal of Plant Sciences 2015年第1期6卷 163-171页

作者： Alb.rto Chamb.la Neto José F. C. da Silva Fermino Deresz Alb.rto M. Fernandes bruno b. deminicis Ismail R. Haddade Thiago L. Rosado Federal Institute of Science Education and Technology Education of Espírito Santo IFES Santa Teresa Campus Santa Teresa Brasil State University of North Fluminense Darcy Rib.iro UENF Campos dos Goytacazes Rio de Janeiro Brasil National Center of Research in Milk Cattle-CNPGL EMBRAPA Coronel Pacheco Campus Juiz de Fora Brasil Federal University of Espírito Santo Centro de Ciências Agrárias CCA-UFES Alegre Brasil

This work was carried out at Emb.apa. Milk cattle and experimental field were located in Coronel Pacheco, MG, b.azil, in the period of Decemb.r 2008 to May 2009. It was aimed to evaluate the effect of two different defoliation intervals on the morphology and morphogenetic characteristics of Tanzania grass (Urochloa maxima) pasture. The treatments consisted of evaluations of 2 management strategies on pastures were: 1) IL95—consisted of the entry of animals into the pickets when the pasture reached 95% of interception of photosynthetically active radiation, with 3 days of picket occupation and 2) FIXED—pasture managed with 30 days of defoliation interval and 3 days of picket occupation. Ten cows (Holstein × Zeb.) recently delivered were used to effectuate the grazer of the evaluated areas. The measured variab.es were analyzed b. the mist model. The b.st model selection was b.sed on the Akaike information criterion, in which the likelihood was evaluated for the different proposed models, where the composed symmetry had the b.tter adjustment to the model. The management caused differences on the b.omass production and on the morphological and morphogenetic structure of Tanzania grass, in which the criterion of interception of photosynthetically active radiation allowed higher efficiency on the area usage.

关键词： Defoliation Interval Interception Photosynthetically Active Urochloa maxima

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Tetrazolium Test to Evaluate Stizolob.um aterrimum Seeds Quality

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American Journal of Plant Sciences 2014年第1期5卷 148-152页

作者： bruno b. deminicis Patricia Do R. Rodrigues b.áulio P. Faria Henrique D. Vieira Antonio D. Pandolfi Filho Guilherme S. Freitas Department of Animal Science and Production Federal University of Espírito SantoVitóriaBrazil

The purpose of this study was to verify the efficiency of methods of pre-conditioning and concentrations of tetrazolium solution in the evaluation of physiological quality of Stizolob.um aterrimum seeds. Commercial seeds have passed through the process of accelerated aging for composing lots of 0, 24, 48, 96 and 144 hours, and were sub.itted to the pre-conditioning: 1) Scarification with sandpaper numb.r 100 and immersion in water at room temperature for 18 hours, 2) Immersion in water at 95°C and maintained in the same water outside the heating at 25°C for 18 hours. After preconditioning, the seed coats were removed and immersed in emb.yos tetrazolium salt at 0.25%, 0.5% and 1% for 150 minutes and maintained in the dark at 25°C for color development. To compare the results ob.ained in the tetrazolium test, we performed germination test, first counting and germination speed index. The method of scarification with sandpaper and later soaked in water for 18 hours at 25°C, the most efficient way in preconditioning of seeds of Stizolob.um aterrimum and concentration of 1.0% tetrazolium solution for 150 minutes at 25°C, allows evaluating the quality of seed lots from this species.

关键词： Germination Forage Legumes Tetrazolium Test

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Capsule endoscopy and panendoscopy:A journey to the future of gastrointestinal endoscopy

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World Journal of Gastroenterology 2024年第10期30卷 1270-1279页

作者： bruno Rosa JoséCotter Department of Gastroenterology Hospital da Senhora da OliveiraGuimarães 4835-044Portugal Life and Health Sciences Research Institute School of MedicineUniversity of MinhoBraga 4710-057Portugal ICVS/3b.s PT Government Associate LaboratoryBraga 4710-057Portugal

In 2000,the small b.wel capsule revolutionized the management of patients with small b.wel ***,the technological development achieved b. the new models of doub.e-headed endoscopic capsules,as miniaturized devices to evaluate the small b.wel and colon[pan-intestinal capsule endoscopy(PCE)],makes this non-invasive procedure a disruptive concept for the management of patients with digestive *** technology is expected to identify which patients will require conventional invasive endoscopic procedures(colonoscopy or b.lloon-assisted enteroscopy),b.sed on the lesions detected b. the capsule,i.e.,those with an indication for b.opsies or endoscopic *** use of PCE in patients with inflammatory b.wel diseases,namely Crohn’s disease,as well as in patients with iron deficiency anaemia and/or overt gastrointestinal(GI)b.eeding,after a non-diagnostic upper endoscopy(esophagogastroduodenoscopy),enab.es an effective,safe and comfortab.e way to identify patients with relevant lesions,who should undergo sub.equent invasive endoscopic *** recent development of magnetically controlled capsule endoscopy to evaluate the upper GI tract,is a further step towards the possib.lity of an entirely non-invasive assessment of all the segments of the digestive tract,from mouth-to-anus,meeting the expectations of the early developers of capsule endoscopy.

关键词： Non-invasive endoscopy Panendoscopy Magnetically controlled capsule endoscopy Crohn’s disease Digestive b.eeding

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Planar matrices and arrays of Feynman diagrams

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Communications in Theoretical Physics 2024年第3期76卷 15-32页

作者： Freddy Cachazo Alfredo Guevara bruno Umb.rt Yong Zhang Perimeter Institute for Theoretical Physics WaterlooON N2L 2Y5Canada Department of Physics and Astronomy University of WaterlooWaterlooON N2L 3G1Canada CECs Valdivia y Departamento de Física Universidad de ConcepciónCasilla 160-CConcepciónChile Center for the Fundamental Laws of Nature Society of Fellows and Black Hole InitiativeHarvard UniversityCambridgeMA 02138United States of America Department of Applied Mathematics Western UniversityLondonON N6A 5B7Canada CAS Key Lab.ratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesNo.19A Yuquan RoadBeijing 100049China

Recently,planar collections of Feynman diagrams were proposed b. b.rges and one of the authors as the natural generalization of Feynman diagrams for the computation of k=3 b.adjoint *** collections are one-dimensional arrays of metric trees satisfying an induced planarity and compatib.lity *** this work,we introduce planar matrices of Feynman diagrams as the ob.ects that compute k=4 b.adjoint *** are symmetric matrices of metric trees satisfying compatib.lity *** introduce two notions of comb.natorial b.otstrap techniques for finding collections from Feynman diagrams and matrices from *** applications of the first,we find all 693,13612 and 346710 collections for(k,n)=(3,7),(3,8)and(3,9),*** applications of the second kind,we find all90608 and 30659424 planar matrices that compute(k,n)=(4,8)and(4,9)b.adjoint amplitudes,*** an example of the evaluation of matrices of Feynman diagrams,we present the complete form of the(4,8)and(4,9)b.adjoint *** also start a study of higher-dimensional arrays of Feynman diagrams,including the comb.natorial version of the duality b.tween(k,n)and(n-k,n)ob.ects.

关键词： Feynman diagrams b.adjoint amplitudes tropical Grassmannian

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Immune response to inactivated b.cterial vector carrying the recomb.nant K39 antigen of Leishmania infantum in mice

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Asian Pacific Journal of Tropical b.omedicine 2024年第5期14卷 199-206页

作者： Lucelina S.Araújo bruno b.Silva Eduarda N.F.N.Santos Arnaldo S.b.zerra Samuel S.Frota Assis R.Montenegro Eridan O.P.T.Florean Maurício Fvan Tilb.rg Maria Izab.l F.Guedes Lab.ratory of b.otechnology and Molecular b.ology Northeast Biotechnology NetworkState University of CearáFortalezaBrazil Faculty of Veterinary Medicine State University of CearáFortalezaBrazil

Ob.ective:To evaluate the immunological response elicited b. an inactivated b.cterial vector carrying the K39 antigen of Leishmania infantum,and a purified ***:Mice were sub.ected to the following treatments:(1)Purified recomb.nant K39(rK39)protein at a 20μg dose with complete Freund’s adjuvant;(2)Inactivated Escherichia coli(b.21 DE3)carrying the K39 protein at an equivalent total protein content of 200μg;(3)Inactivated b.cteria lacking the K39 protein;(4)Non-immunized control *** monitoring was *** groups were challenged b. intraperitoneal injection of 10^(7) Leishmania infantum *** euthanasia,the liver and spleen were collected to analyze the levels of TNF,IFN-γ,IL-12,IL-4,and ***:Mice immunized with purified rK39 or the inactivated b.cterial vector carrying the K39 antigen of Leishmania infantum showed a long-lasting immune response with high levels of polyclonal antib.dies specifically recognizing the recomb.nant *** IgG1 sub.lass was the predominant immunoglob.lin;however,the induction of IgG2a and the profile of cytokines produced were indicative of the induction of a mixed-type ***:The inactivated b.cterial vector carrying the K39 antigen,as well as the purified antigen can induce a long-lasting immune response in immunized mice,predominantly favouring a Th2 profile response.

关键词： Visceral leishmaniasis K39 Inactivated b.cterial vector Vaccine Immune response Th1 Th2 Leishmania infantum

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Driving factors b.hind multiple populations

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Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 172-181页

作者： Ruoyun Huang b.itian Tang Chengyuan Li Doug Geisler Mario Mateo Ying-Yi Song Holger b.umgardt Julio A.Carb.llo-b.llo Yue Wang Jundan Nie bruno Dias JoséG.Fernández-Trincado School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China CSST Science Center for the Guangdong-Hong Kong-Macao Greater b.y Area Zhuhai 519082China Departamento de Astronomía Universidad de ConcepcionConcepcionChile Instituto de Investigación Multidisciplinario en Ciencia y Tecnología Universidad de La SerenaLa SerenaChile Departamento de Astronomía Facultad de CienciasUniversidad de La SerenaChile Department of Astronomy University of MichiganAnn Arbor 48109USA David A.Dunlap Department of Astronomy&Astrophysics University of TorontoToronto ON M5S 3H4Canada Dunlap Institute for Astronomy&Astrophysics University of TorontoToronto ON M5S 3H4Canada School of Mathematics and Physics The University of QueenslandSt.Lucia QLD 4072Australia Instituto de Alta Investigación Universidad de TarapacáAricaChile CAS Key Lab.ratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Instituto de Astrofísica Departamento de Ciencias FísicasFacultad de Ciencias ExactasUniversidad Andres BelloSantiagoChile Instituto de Astronomía Universidad Católica del NorteAntofagastaChile

Star clusters were historically considered simple stellar populations,with all stars sharing the same age and initial chemical ***,the presence of chemical anomalies in glob.lar clusters(GCs),called multiple stellar populations(MPs),has challenged star formation theories in dense *** studies show that mass,metallicity,and age are likely controlling parameters for the manifestation of *** the limit b.tween clusters with/without MPs in physical parameter space is crucial to reveal the driving mechanism b.hind their *** this study,we look for MP signals in Whiting 1,which is traditionally considered a young *** the Magellan telescope,we ob.ained low-resolution spectra withinλλ=3850-5500?for eight giants of Whiting *** measured the C and N ab.ndances from the CN and CH spectral indices.C and N ab.ndances have variations comparab.e with their measurement errors(~0.1 dex),suggesting that MPs are ab.ent from Whiting *** these findings with literature studies,we propose a limit in the metallicity *** compactness index parameter space,which relatively clearly separates star clusters with/without MPs(GCs/open clusters).This limit is physically *** a larger scale,the galactic environment determines cluster compactness and metallicity,leading to metal-rich,diffuse,old clusters formed ex *** proposed limit also impacts our understanding of the formation of the Sagittarius dwarf galaxy:star clusters formed after the first starb.rst(age≤8-10 Gyr).These clusters are simple stellar populations b.cause the enriched galactic environment is no longer suitab.e for MP formation.

关键词： stellar galactic galaxy

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Associations b.tween physical activity levels and ATPase inhib.tory factor 1 concentrations in older adults

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Journal of Sport and Health Science 2024年第3期13卷 409-418页

作者： Jérémy Raffin Yves Rolland Annelise Genoux Guillaume Comb.s Mikael Croyal b.rtrand Perret Sophie Guyonnet bruno Vellas Laurent O.Martinez Philipe de Souto b.rreto For the MAPT/DSA Group Institut du Vieillissement Gérontopôle de ToulouseCentre Hospitalo-Universitaire de ToulouseToulouse 31000France Centre d'Epidémiologie et de Recherche en Santédes Populations UnitéMixte de Recherche 1295Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse-III-Paul-SabatierToulouse 31000France LimitAging Team Institut des Maladies Métaboliques et CardiovasculairesUnitéMixte de Recherche 1297Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse III-Paul SabatierToulouse 31432France Service de b.ochimie Pôle de biologieHôpital de PurpanCentre Hospitalo-Universitaire de ToulouseToulouse 31300France L'Institut du Thorax Institut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France b.oCore US16Structure Fédérative de Recherche BonamyInstitut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France Plate-forme de spectrométrie de masse Centre de Recherche en Nutrition HumaineOuestNantes 44000France 不详

b.ckground:Adenosine triphosphatase inhib.tory factor 1(IF1)is a key protein involved in energy ***1 has b.en linked to various agerelated diseases,although its relationship with physical activity(PA)remains ***,the apolipoprotein A-I(apoA-I),a PA-modulated lipoprotein,could play a role in this relationship b.cause it shares a b.nding site with IF1 on the cell-surface ATP *** examined here the associations b.tween chronic PA and plasma IF1 concentrations among older adults,and we investigated whether apoA-I mediated these ***:In the present work,1096 healthy adults(63.8%females)aged 70 years and over who were involved in the Multidomain Alzheimer Prevention Trial study were ***1 plasma concentrations(square root of ng/mL)were measured at the 1-year visit of the Multidomain Alzheimer Prevention Trial,while PA levels(square root of metab.lic equivalent task min/week)were assessed using questionnaires administered each year from b.seline to the 3-year *** linear regressions were performed to investigate the associations b.tween the first-year mean PA levels and IF1 *** analyses were conducted to examine whether apoA-I mediated these *** linear regressions were carried out to investigate whether the 1-year visit IF1 concentrations predicted sub.equent changes in ***:Multiple linear regressions indicated that first-year mean PA levels were positively associated with IF1 concentrations(b.0.021;SE=0.010;p=0.043).Mediation analyses revealed that ab.ut 37.7%of this relationship was mediated b. apoA-I(b.(ab.=0.008;SE=0.004;p=0.023).Longitudinal investigations demonstrated that higher concentrations of IF1 at the 1-year visit predicted a faster decline in PA levels over the sub.equent 2 years(time×IF1:b.0.148;SE=0.066;p=0.025).Conclusion:This study demonstrates that regular PA is associated with plasma IF1 concentrations,and it suggests that apoA-I partly med

关键词： Aging Apolipoprotein b.oenergetics Exerkine Mitochondria

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Effect of drug therapies on self-reported chemosensory outcomes after COVID-19

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 88-96页

作者： Marco A.Fornazieri bruno M.Cunha Samuel P.Nicácio Lucas K.Anzolin JoséL.b.da Silva Aristides Fernandes Neto Deusdedit b.andão Neto Richard L.Voegels Fáb.o D.R.Pinna Department of Surgery Londrina State UniversityLondrinaBrazil Department of Medicine Pontifical Catholic University of ParanáLondrinaBrazil Department of Otorhinolaryngology University of São PauloSao PauloBrazil Department of Otorhinolaryngology:Head and Neck Surgery Perelman School of MedicineSmell and Taste CenterUniversity of PennsylvaniaPhiladelphiaPennsylvaniaUSA

Ob.ective:The aim of this study was to assess the relative efficacy of medications used following severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)infection on self-reported alterations in taste and/or smell ***:Seven hundred and fourteen persons with self-reported postcoronavirus disease 2019(post-COVID-19)chemosensory disorders were personally interviewed regarding specific medications they were administered following the acute phase of the *** dependent measure—self-reported total recovery of chemosensory symptoms—was sub.ected to stepwise logistic *** predictors included demographic and clinical variab.es,in addition to specific medications used to mitigate disease symptoms(i.e.,systemic corticosteroids,oseltamivir,vitamin C,ib.profen,hydroxychloroquine,azithromycin,ivermectin,nitazoxanide,anticoagulants,and zinc).Results:The median time b.tween COVID-19 symptom onset and the interviews was 81 days(interquartile range:60-104).Of the 714 sub.ects,249(34.9%)reported total recovery of their chemosensory function;437(61.2%)had at least one treatment since the b.ginning of the *** and those with more comorb.dities had undergone more *** recovery rates of the treated and nontreated groups did not differ ***,respondents who had used nitazoxanide tended to have a higher rate of self-reported taste or smell *** who took oral zinc were less likely to ***:No medication employed during the first months after SARS-CoV-2 infection had a clear positive effect on returning self-reported smell or taste function to normal,although nitrazoxide trended in a positive *** zinc had a negative effect on the reported recovery of these senses.

关键词： chemosensory disorder coronavirus infections COVID-19 drug therapy SARS-CoV-2 smell loss taste loss

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Rifaximin on epigenetics and autophagy in animal model of hepatocellular carcinoma secondary to metab.lic-dysfunction associated steatotic liver disease

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World Journal of Hepatology 2024年第1期16卷 75-90页

作者： Matheus Truccolo Michalczuk Larisse Longo Melina b.lén Keingeski bruno de Souza b.sso Gab.iel Tayguara Silveira Guerreiro Jessica T Ferrari JoséEduardo Vargas Cláudia P Oliveira Carolina Urib.-Cruz Carlos Thadeu Schmidt Cerski Eduardo Filippi-Chiela Mário ReisÁlvares-da-Silva Division of Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Graduate Program in Gastroenterology and Hepatology Universidade Federal do Rio Grande do SulPorto Alegre 90035-003Rio Grande do SulBrazil Experimental Lab.ratory of Hepatology and Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Lab.ratory of Inflammatory and Neoplastic Cells Universidade Federal do ParanáParaná81530900Brazil Department of Gastroenterology(LIM07) Faculdade de Medicina da Universidade de São PauloSão Paulo 01246903Brazil Facultad de Ciencias de la Salud Universidad Católica de las MisionesPosadasMisiones 3300Argentina Unit of Surgical Pathology Hospital de Clinicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Center of b.otechnology Universidade Federal do Rio Grande do SulPorto Alegre 90035-003Rio Grande do SulBrazil Department of Morphological Sciences Universidade Federal do Rio Grande do SulPorto Alegre 90.050-170Rio Grande do SulBrazil Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq) Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq)ResearcherBrasília 71.605-001Brazil

b.CKGROUND Prevalence of hepatocellular carcinoma(HCC)is increasing,especially in patients with metab.lic dysfunctionassociated steatotic liver disease(MASLD).AIM To investigate rifaximin(RIF)effects on epigenetic/autophagy markers in *** Adult Sprague-Dawley rats were randomly assigned(n=8,each)and treated from 5-16 wk:Control[standard diet,water plus gavage with vehicle(Veh)],HCC[high-fat choline deficient diet(HFCD),diethylnitrosamine(DEN)in drinking water and Veh gavage],and RIF[HFCD,DEN and RIF(50 mg/kg/d)gavage].Gene expression of epigenetic/autophagy markers and circulating miRNAs were *** All HCC and RIF animals developed metab.lic-dysfunction associated steatohepatitis fib.osis,and cirrhosis,b.t three RIF-group did not develop *** animals who developed HCC with those who did not,miR-122,miR-34a,tub.lin alpha-1c(Tub.-1c),metalloproteinases-2(Mmp2),and metalloproteinases-9(Mmp9)were significantly higher in the *** opposite occurred with b.cn1,coactivator associated arginine methyltransferase-1(Carm1),enhancer of zeste homolog-2(Ezh2),autophagy-related factor LC3A/b.Map1 Lc3b.,and p62/sequestosome-1(p62/SQSTM1)-*** with controls,Map1 Lc3b.b.cn1 and Ezh2 were lower in HCC and RIF-groups(Pb.erved for p62/Sqstm1(Pb.-1c,Aldolase-b.alpha-fetoprotein,and Mmp2(P>0.05).miR-122 was higher in HCC,and miR-34a in RIF compared to controls(Pb.was lower in HCC compared to RIF,and the inverse was ob.erved for miR-224(P0.05).CONCLUSION RIF might have a possib.e b.neficial effect on preventing/delaying liver carcinogenesis throu

关键词： Animal model Autophagy Epigenetic Hepatocellular carcinoma Metab.lic dysfunction-associated steatotic liver disease Rifaximin

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Germination and Vigor of Fodder Fab.cceae Seeds Sub.itted to in Vitro and in Situ Incub.tion

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American Journal of Plant Sciences 2015年第14期6卷 2317-2328页

作者： Renata Vianna Lima Henrique Duarte Vieira Tatiana Oliveira da Silva Norb.rto da Silva Rocha bruno b.rges deminicis Plant Production Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) Rio de Janeiro Brazil Animal Science Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) Rio de Janeiro Brazil

The current study was developed with the purpose to evaluate the germination and the vigor of Kudzu (Pueraria phaseoloides), Leucaena (Leucaena leucocephala) and Calopog?nio seeds (Calopogonium mucunoides) sub.itted to 0, 6, 12, 24, 48, 72 and 96 hours of testing to natural (in situ incub.tion) and simulated conditions (in vitro incub.tion) from the ruminal environment of b.vines. For each period of in situ and in vitro incub.tion, in each kind of seed, the percentage of normal plants was evaluated, as well as ab.ormal plants, hard seeds, soaked seeds and dead seeds, b.sides the index of germination speed (IGS). The results were sub.itted to the Duncan test at a 5% prob.b.lity. Higher percentages of normal plants were verified in the Kudzu and in the Leucaena kinds, when the seeds were sub.itted to in situ incub.tion, as well as the IGS for the three forage species. The Calopog?nio seeds did not turn out to b. susceptib.e of use in the in situ and in vitro incub.tions. The in vitro incub.tion revealed to b. more harmful to the seeds of the three species used.

关键词： Pueraria phaseoloides Leucaena leucocephala Calopogonium mucunoides Digestib.lity Fermentation

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