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Open Journal of Preventive Medicine 2013年第5期3卷 363-367页

作者： Adrienne G. Clark Elizabeth A. Dennis Parker Jyoti S. Savla kevin P. Davy brenda M. Davy Department of Human Development Virginia Tech Blacksburg USA Department of Human Nutrition Foods and Exercise Virginia Tech Blacksburg USA Department of Human Nutrition Foods and Exercise Virginia Tech Blacksburg USA Lombardi Comprehensive Cancer Center Georgetown University Medical Center Washington D.C. USA

Obesity and impaired glucose homeostasis in older adults place these individuals at risk for diabetes. Dehydration, glucose homeostasis, and insulin resistance are related;while aging and dehydration are associated with decreased glucose tolerance, weight loss can improve glycemia. For older adults following hypocaloric diets, additional water consumption may lead to greater weight loss. Further more, research suggests an association between insulin resistance and the body water retention hormone, arginine vasopressin (AVP). Analysis of the association between plasma copeptin (an AVP derivative) and fasting glucose, insulin, and homeostasis model assessment of insulin resistance (HOMA-IR) may provide further insight into the relationship between dehydration and diabetes risk. Our objective was to investigate the possibility that increased water consumption among older adults (n = 29, BMI = 31 ± 1 kg/m2, age = 62 ± 1 years) could improve glucose homeostasis beyond that observed with weight loss, as well as associations between plasma copeptin and diabetes risk. This retrospective analysis utilized data from a previous investigation, in which obese/overweight older adults were assigned to one of two groups: 1) Water: consume 500 ml of water prior to three daily meals over a 12-week hypocaloric diet intervention, or 2) Non-water: hypocaloric diet alone. In the present analysis, fasting plasma glucose and insulin, HOMA-IR, and plasma copeptin were evaluated, and compared to urinary specific gravity (USG), drinking water consumption, and body weight. Analyses performed using group assignment, volume of drinking water consumed or among a subgroup pair-matched for weight loss and sex did not reveal significant differences between groups. However in the full sample, plasma insulin concentration was associated with USG (r = 0.512,

关键词： Older Adults Diabetes Glucose Water Consumption Hydration

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金属卡拜与双卡宾的转换和α-夺氢反应

金属卡拜与双卡宾的转换和α-夺氢反应

Restraint Induces Sickness Responses Independent of Injection with Epstein-Barr Virus (EBV)-Encoded dUTPase

中国化学会第26届学术年会无机与配位化学分会场

作者： brenda A.Dougan 薛子陵美国田纳西大学化学系美国田纳西大学化学系

＜正＞金属卡宾和卡拜化合物被广泛地应用烯烃和炔烃催化复分解反应。我们曾报道了卡拜-烷基膦配合物与双卡宾-烷基膦配合物进行α-氢转移反应并达到平衡。我们最近研究了（Me3SiCH2）3W（≡CSiMe3）

关键词：卡宾卡拜烷基膦

来源： cnki会议评论

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Journal of Behavioral and Brain Science 2014年第11期4卷 491-505页

作者： Taryn G. Aubrecht Bachir Abi Salloum Maria Eugenia Ariza Marshall Williams brenda Reader Ronald Glaser John Sheridan Randy J. Nelson Departments of Neuroscience The Ohio State University Columbus OH USA Departments of Molecular Virology Immunology & Medical Genetics The Ohio State University Columbus OH USA Institute for Behavioral Medicine Research Wexner Medical Center Comprehensive Cancer Center The Ohio State University Columbus OH USA Division of Bioscience College of Dentistry The Ohio State University Columbus OH USA

Most adult humans have been infected by Epstein-Barr virus (EBV), a putative cause of chronic fatigue syndrome, and carry latent EBV. The EBV-encoded dUTPase can induce sickness responses in mice and chronic stress exacerbates this response. Because individuals often adapt to chronic stress, we tested the hypothesis that acute restraint stress would potentiate these sickness responses elicited by EBV-encoded dUTPase. Male CD-1 mice were injected daily for one or three days with either saline or EBV-encoded dUTPase. Additionally, mice from each condition were either restrained for three hours daily or left undisturbed during the light phase when mice are inactive. Restraint decreased weight gain during the one- and three-day experiments. Restraint in saline injected mice increased anxiety-like behavior in the open field during the three-day experiment. There were no behavioral differences during the one-day experiment. Restraint stress had no effect when experienced acutely on one day, but did produce a sickness response after three days of exposure regardless of saline or dUTPase injection. In contrast to the effects of chronic stress and EBV-encoded dUTPase on the sickness response, acute stress did not affect sickness responses in association with EBV-encoded dUTPase. Thus, dUTPase does not appear to provoke the same sickness responses after acute stress as compared to chronic stress.

关键词： Epstein-Barr Virus Restraint Stress Sickness Response Anxiety-Like and Depressive-Like Behaviors

Hematology and blood serum chemistry reference intervals for children in Iganga district of Uganda

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Health 2013年第8期5卷 1261-1267页

作者： Fred kironde Musa Sekikubo Halima Naiwumbwe Fatuma Namusoke William Buwembo Steven kiwuwa brenda Oketch Ramadhani Noor Roma Chilengi Edison Mworozi Mark kaddumukasa African Malaria Network Trust Dar-es Salaam Tanzania Centre for Infectious Disease Research in Zambia (CIDRZ) Lusaka Zambia Makerere University College of Health Sciences Kampala Uganda

In this study, normal ranges for hematology and serum biochemistry in children aged 1 to 5 years inUgandawere determined. By a cross-sectional study, 1168 children from Iganga, a prospective site for clinical trials in Uganda, were screened. From 1168 households, 460 children were selected for enrollment, while 600 (58%) were excluded because of either a history of fever in the previous 24 hours, presence of asexual malaria parasites in the peripheral blood or presence of fever. Accordingly, 460 children (39.4%) of median age = 3 years were enrolled in the baseline study. While the lower limits of hemoglobin, hematocrit levels, mean corpuscular volume and platelet counts for the Ugandan children were found to be less than conventional reference values of Caucasisan children, the white blood cell count reference values were higher than the international intervals. On the other hand, the upper limits of the reference intervals for serum transaminases, bilirubin, creatinine, urea, total protein and albumin in sera of the Ugandan children were higher than the corresponding values for a Caucasian pediatric population. This study showed that, if hematology test results of the Ugandan children were assessed against “imported” international reference values, up to 44.6% of the study participants would have been excluded from clinical trials or would have been reported as adverse events in such trials. The present study was not only the first report of serum biochemistry reference ranges for children aged one to five years in Uganda but also one of very few such studies in Africa.

关键词： Normal Intervals Reference Uganda Children Hematology Serum Biochemistry Iganga

The Safety of Cannabis Use in Pregnancy

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Open Journal of Obstetrics and Gynecology 2021年第11期11卷 1437-1445页

作者： Simona Senovaityte Alexander Nguyen Solhee Han brenda La Faithful Anane-Asane Rouna Mohran Sterling Lee Anthony Monzon Omar Samara Derrick Murcia Shrey Purohit University of Colorado Anschutz Medical Campus Aurora Colorado USA

Based on self-reported surveys conducted by the Substance Abuse and Mental Health Services Administration, cannabis use in pregnant females has increased over the years. Despite the increasing trend, the relationship between cannabis use and fetal outcomes is not fully understood. This review paper evaluates the literature investigating the short-term and long-term fetal outcomes resulting from cannabis use during pregnancy. Additionally, the risk of chronic marijuana use leading to cannabis hyperemesis syndrome has been highlighted in this paper using conclusions compiled from several case studies. Several studies linked delayed mental growth and reduced cognitive function with prenatal cannabis use, but the literature was limited to lower-quality observational studies and could not establish causality. One systematic review investigated short-term outcomes of low birth rates and preterm deliveries, where marijuana use in conjunction with tobacco use was associated with more preterm deliveries. Another study found that six-year-old patients exposed to cannabis prenatally were more likely to score lower in different categories on the Stanford-Binet scale test, which measures intelligence. The exposure in the first, second, or third trimester was associated with lower composite or subcategory scores such as verbal reasoning or short-term memory. Despite these results, the studies evaluated had limitations. They could not establish a clear relationship between cannabis use and fetal outcomes, but the literature showed a similar pattern of health, social and economic inequities among the populations who self-reported cannabis and substance use and non-users. Current organization guidelines advise against the use of cannabis use during pregnan

关键词： Causality Preterm Deliveries Low-Birth Rates Stanford-Binet Scale Test Trimester Inequities

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英格兰的教师培训

物理教师（高中版） 2000年第3期21卷 27-29页

作者： brenda M Jennison 李科敏徐旭玲英国剑桥大学教育学院广西师范大学物理系

Process for the Obtention of Coumaric Acid from Coumarin: Analysis of the Reaction Conditions

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Advances in Chemical Engineering and Science 2013年第3期3卷 195-201页

作者： Néstor N. López-Castillo Alma D. Rojas-Rodríguez brenda M. Porta M. Javier Cruz-Gómez Chemical Engineering Department of the Faculty of Chemistry Universidad Nacional Autónoma de México (UNAM) Coyoacan D. F. México México

Coumaric acid can be obtained from basic hydrolysis of coumarin, through a reaction process consisting on opening the lactone ring and cis-trans isomerization. Parameters such as reaction time, temperature, NaOH concentration, solvent and reaction atmosphere, have been thoroughly studied and analyzed, in order to determine the appropriate conditions for the maximum conversion efficiency of coumarin into coumaric acid. Experimental results show that the best conditions are a 1 hour reaction time, at 160℃, with a 20% sodium hydroxide aqueous solution, and in an inert reaction atmosphere.

关键词： Coumarin Coumaric Acid Ester Hydrolysis

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劳伦斯有妇之夫

Cost and Calorie Analysis of Fast Food Consumption in College Students

丛书名：编译传记

1999年

作者：（美）布伦达·马多克斯（brenda Maddox）邹海仑等译

编译传记

ISBN: (纸本)7801092252

编译传记

关键词：历史、地理传记各国人物传记

来源：汇雅图书（南通市图书馆... 评论

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Food and Nutrition Sciences 2012年第7期3卷 942-946页

作者： kimberly B. Heidal Sarah E. Colby Ginger T. Mirabella khalid S. Al-Numair brenda Bertrand kevin H. Gross Department of Community Health Sciences College of Applied Medical Sciences-King Saud University Riyadh Saudi Arabia Department of Nutrition Science East Carolina University Greenville North Carolina USA Department of Nutrition Science East Carolina University Greenville North Carolina USA 2Sarah E. Colby Department of Nutrition University of Tennessee-Knoxville Knoxville TN USA Sarah E. Colby Department of Nutrition University of Tennessee-Knoxville Knoxville TN USA Statistics & Research Consultant East Carolina University Greenville North Carolina USA

The purpose of this research was to assess money spent and calories consumed by college students from fast food restaurants located on and around a southern college campus. A convenience sample (n = 152) of undergraduate college students (aged 18 - 24) at a southern university participated in a survey that measured dietary intake from seven local fast food chains using a researcher developed food frequency questionnaire and a lifestyle behavior survey that collected data on health practices. A strong positive correlation was found between total monthly fast food expense and total monthly fast food caloric consumption (r(150) = 0.94, p t test comparing the mean monthly fast food restaurant expense males to females found a significant difference between the two groups (t(150) = 4.19, p < 0.05).The more money spent by college students contributed to a higher amount of calories consumed from fast food in a typical month. Future research needs to determine if college students are contributing to the high obesity rate and if limiting fast food restaurants on and around college campuses would help decrease fast food consumption in college students.

关键词： Cost Analysis Students Health Food Energy Intake