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Relationship between preoperative psychological stress and shortterm prognosis in elderly patients with femoral neck fracture

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World Journal of Psychiatry 2024年第6期14卷 838-847页

作者： Wen-Hui Fu Zhi-Long Hu Yuan-Jun Liao Ri-Jiang Chen Jian-bin qiu Wu-Tang Que Wan-Tao Wang Wei-Hua Li Wei-bin Lan Department of Orthopedics Longyan First Affiliated Hospital of Fujian Medical UniversityLongyan 361000Fujian ProvinceChina

BACKGROUND Older adults are at high risk of femoral neck fractures(FNFs).Elderly patients face and adapt to significant psychological burdens,resulting in different degrees of psychological stress response.Total hip replacement is the preferred treatment for FNF in elderly patients;however,some patients have poor postoperative prognoses,and the underlying mechanism is unknown.We speculated that the postoperative prognosis of elderly patients with FNF may be related to preoperative psychological stress.AIM To explore the relationship between preoperative psychological stress and the short-term prognosis of elderly patients with FNF.METHODS In this retrospective analysis,the baseline data,preoperative 90-item Symptom Checklist score,and Harris score within 6 months of surgery of 120 elderly patients with FNF who underwent total hip arthroplasty were collected.We analyzed the indicators of poor short-term postoperative prognosis and the ability of the indicators to predict poor prognosis and compared the correlation between the indicators and the Harris score.RESULTS Anxiety,depression,garden classification of FNF,cause of fracture,FNF reduction quality,and length of hospital stay were independent influencing factors for poor short-term postoperative prognoses in elderly patients with FNF(P<0.05).The areas under the curve for anxiety,depression,and length of hospital stay were 0.742,0.854,and 0.749,respectively.The sensitivities of anxiety,depression,garden classification of FNF,and prediction of the cause of fracture were 0.857,0.786,0.821,and 0.821,respectively.The specificities of depression,FNF quality reduction,and length of hospital stay were the highest at 0.880,0.783,and 0.761,respectively.Anxiety,depression,and somatization scores correlated moderately with Harris scores(r=-0.523,-0.625,and-0.554;all P<0.001).CONCLUSION Preoperative anxiety,depression,and somatization are correlated with poor short-term prognosis in elderly patients with FNF and warrant consideration.

关键词： Psychological stress Old age Femoral neck fracture Hip replacement Short-term prognosis Correlation

Evaluation of bronchoscopic direct vision glottis anesthesia method in bronchoscopy

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World Journal of Clinical Cases 2023年第21期11卷 5108-5114页

作者： Jie Lang Zhi-Zhen Guo Shu-Shan Xing Jian Sun bin qiu Yu Shu Zhi-Qiang Wang Gui-Xiang Liu Department of Thoracic Surgery Tangshan People’s HospitalTangshan 063000Hebei ProvinceChina Department of Nephrology Kailuan General HospitalTangshan 063000Hebei ProvinceChina Department of Oncology Tangshan Central HospitalTangshan 063000Hebei ProvinceChina

BACKGROUND Fibrobronchoscopy is a common adjunct tool that requires anesthesia and is widely used in the diagnosis and treatment of various respiratory diseases.However,current anesthesia methods,such as spray,nebulized inhalation,and cricothyroid membrane puncture,have their own advantages and disadvantages.Recently,studies have shown that bronchoscopic direct-view glottis anesthesia is a simple and inexpensive method that shortens the examination time and provides excellent anesthetic results.AIM To evaluate the effectiveness of bronchoscopic direct vision glottis anesthesia for bronchoscopy.METHODS The study included 100 patients who underwent bronchoscopy during thoracic surgery.A random number table method was used to divide the patients into control and observation groups(50 patients each).The control and observation groups were anesthetized using the nebulized inhalation and bronchoscopic direct vision glottis method,respectively.Hemodynamic indices[systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR),and oxygen saturation(SpO_(2))before(T1),5 min after anesthesia(T2),and at the end of the operation(T3)]serum stress hormone indices[norepinephrine(NE),epinephrine(E),adrenocorticotropic hormone(ACTH),and cortisol(Cor)before and after treatment]were compared between the 2 groups.Adverse effects were also RESULTS At T2 and T3,SBP,DBP,and HR were lower in the observation group than the control group,whereas SpO_(2) was higher than the control group[(119.05±8.01)mmHg vs(127.05±7.83)mmHg,(119.35±6.66)mmHg vs(128.39±6.56)mmHg,(84.68±6.04)mmHg vs(92.42±5.57)mmHg,(84.53±4.97)mmHg compared to(92.57±6.02)mmHg,(74.25±5.18)beats/min compared to(88.32±5.72)beats/min,(74.38±5.31)beats/min compared to(88.42±5.69)beats/min,(97.36±2.21)%vs(94.35±2.16)%,(97.42±2.36)%vs(94.38±2.69%],with statistically significant differences(all P<0.05).After treatment,NE,E,ACTH,and Cor were significantly higher in both groups than before treatment,but were lower in the observation group than in the control group[(68.25±8.

关键词： Direct bronchoscopy Glottis anesthesia method Bronchoscopy Airway Sedation

基于深度强化学习的车载边缘计算功率分配方法

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北京邮电大学学报 2024年第2期47卷 81-89页

作者：邱斌王云霄肖海林桂林理工大学信息科学与工程学院桂林541004 广西嵌入式技术与智能系统重点实验室桂林541004 湖北大学计算机与信息工程学院武汉430062

针对车载边缘计算环境下车辆移动引起的车载时变信道和任务随机到达问题,提出了一种基于深度强化学习的计算卸载和功率分配方法。首先,设计了双向车道场景下基于非正交多址的“端-边-云”三层卸载模型;接着,结合该模型的通信、计算、缓... 详细信息

针对车载边缘计算环境下车辆移动引起的车载时变信道和任务随机到达问题,提出了一种基于深度强化学习的计算卸载和功率分配方法。首先,设计了双向车道场景下基于非正交多址的“端-边-云”三层卸载模型;接着,结合该模型的通信、计算、缓存资源以及车辆的移动性,进一步确立了车载用户功率和缓存延迟长期累积总成本最小化的联合优化问题;最后,考虑到车载边缘计算网络的动态、时变和随机特性,提出了基于深度确定性策略梯度的分布式智能算法,以获取最优功率分配机制。仿真实验结果显示,相较于传统方法,所提方法在减少总成本方面具有显著优势。

关键词：车载边缘计算计算卸载功率分配服务缓存深度确定性策略梯度

A Model Predicting Lymph Node Status for Patients with Clinical Stage TlaNO-2MO Nonsmall Cell Lung Cancer

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Chinese Medical Journal 2017年第4期130卷 398-403页

作者： Ruo-Chuan Zang bin qiu Shu-Geng Gao Jie He Department of Thoracic Surgery Peking Union Medical College Cancer Hospital and Chinese Academy of Medical Sciences Beijing 100021 China

Background： Lymph node status of patients with early-stage nonsmall cell lung cancer has an influence on the choice of surgery. To assess the lymph node status more correspondingly and accurately, we evaluated the relationship between the preoperative clinical variables and lymph node status and developed one model for predicting lymph node involvement. Methods： We collected clinical and dissected lymph node information of 474 patients with clinical stage TlaN0-2M0 nonsmall cell lung cancer （NSCLC）. Logistic regression analysis of clinical characteristics was used to estimate independent predictors of lymph node metastasis. The prediction model was validated by another group. Results： Eighty-two patients were diagnosed with positive lymph nodes （17.3%）, and four independent predictors of lymph node disease were identified： larger consolidation size （odds ratio [OR] = 2.356, 95% confidence interval [CI]： 1.517-3.658, P 〈 0.001）, central tumor location （OR = 2.810, 95% CI： 1.545-5.109, P = 0.001 ）, abnormal status of tumor marker （OR = 3.190, 95% CI： 1.797-5.661, P 〈 0.001 ）, and clinical N1-N2 stage （OR = 6.518, 95% CI： 3.242-11.697, P 〈 0.001）. The model showed good calibration （Hosmer-Lemeshow goodness-of-fit, P 〈 0.766） with an area under the receiver operating characteristics curve （AUC） of 0.842 （95% [CI]： 0.797-0.886）. For the validation group, the AUC was 0.810 （95% CI： 0.731-0.889）. Conclusions： The model can assess the lymph node status of patients with clinical stage TlaN0-2M0 NSCLC, enable surgeons perform an individualized prediction preoperatively, and assist the clinical decision-making procedure.

关键词： Carcinoma Diagnosis Lymph Nodes Nonsmall Cell Lung Cancer Predictive Models

Bioinspired manganese complexes catalyzed epoxidation for the synthesis of the epoxyketone fragment of carfilzomib

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Chinese Chemical Letters 2019年第3期30卷 698-701页

作者： bin qiu Chungu Xia Wei Sun Key Laboratory for Oxo Synthesis and Selective Oxidation Suzhou Research Institute of LICP Lanzhou Institute of Chemical Physics (LICP) Chinese Academy of Sciences University of Chinese Academy of Sciences

We report herein an efficient catalytic epoxidation reaction for the synthesis of epoxyketone(tert-butyl((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate), which is an important synthetic intermediate of carfilzomib. A series of bioinspired manganese complexes bearing N4 ligands are carefully investigated in the epoxidation of enone precursor with H_2O_2 as oxidant in the presence of carboxylic acid(e.g., acetic acid).

关键词： Catalytic epoxidation Bioinspired manganese complexes Hydrogen peroxide Epoxyketone Carfilzomib

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基于事件演化图的多标记事件预测模型

计算机工程 2024年第4期50卷 132-140页

作者：王华珍许泽孙悦丘斌陈坚邱强斌华侨大学计算机科学与技术学院福建厦门361021 华侨大学厦门市计算机视觉与模式识别重点实验室福建厦门361021 智业软件股份有限公司福建厦门361008

多标记事件预测是指预测多个相关联的事件是否会在未来发生,相比传统单标记事件预测,需要同时预测多个目标事件。现有的事件预测研究忽略各领域存在的多标记事件情境,且对多标记事件预测研究较少。提出一种基于事件演化图的多标记事件... 详细信息

多标记事件预测是指预测多个相关联的事件是否会在未来发生,相比传统单标记事件预测,需要同时预测多个目标事件。现有的事件预测研究忽略各领域存在的多标记事件情境,且对多标记事件预测研究较少。提出一种基于事件演化图的多标记事件预测模型(MLEP),以实现基于事件演化图(EEG)的多标记事件预测研究模式。首先基于事件链构建事件演化图;然后对多标记事件预测问题进行问题转换,将多标记问题转化为单标记问题,利用事件表示学习方法获取所有事件的向量表示,对多标记事件进行编码;最后采用门控图神经网络(GGNN)框架构建多标记事件预测模型,根据相似度匹配出最优的后续事件,实现多标记事件的预测。在真实数据集上的实验结果表明,MLEP模型可以有效地预测出多标记事件,预测准确率达到了65.58%,性能优于大多现有的基准模型,提升幅度达到了4.94%以上。通过消融实验也证明了更好的事件表示学习方法对事件具有较好的表示效果,提升多标记事件预测的性能。

关键词：多标记事件演化图事件表示学习门控图神经网络事件预测

Research Progress on Acupuncture Therapy in Infertility: A Bibliometric Analysis from 2000 to 2021

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Chinese Medicine 2023年第3期14卷 181-207页

作者： Nuan Wen bin qiu Ping Wang Ran Li Department of Chinese Medicine Weifang Nursing Vocational College Weifang China Department of Chinese Medicine Weifang Weien Hospital Weifang China Department of Gynaecology and Obstetrics Weifang Weien Hospital Weifang China

Objective: To investigate the research progress and new trend of acupuncture in the treatment of infertility from 2000 to 2021. Methods: The literature review was conducted on acupuncture and moxibustion treatment of infertility from 2000 to 2021 from the Web of Science core collection and PubMed. CiteSpace and VOSviewer were used to analyze the annual number of articles, countries, institutions, authors, journals, references and keywords. Statistical Analysis Toolkit for Informetrics 3.2 (SATI) and IBM SPSS Modeler 18.0 were employed to draw the maps of core acupoints and acupuncture approaches. Results: A total of 316 articles were included. From 2000 to 2021 the number of publications has been ever increased with certain fluctuations. The United States was the most productive country. Heilongjiang University of Chinese Medicine was the most active institution. Stener-Victorin E was the highest cited author. Fertility and Sterility was the most prolific journal. Paulus We, 2002 was the highest co-citation literature. SP6 (Sanyinjiao) was the most commonly used acupoint. Manual acupuncture was the most commonly used method. Conclusions: The study of acupuncture in the treatment of infertility is characterized by multinational, multi-institutional participation and close regional cooperation. Acupuncture is a potentially effective therapy for infertility. Due to a lack of research quality and difficulties in performing double-blind, high-quality clinical evidence is urgently required. A complete acupuncture therapy system for infertility should be gradually constructed.

关键词： Acupuncture Infertility Bibliometric Analysis CiteSpace VOSviewer

广东省乐昌林场森林管护中存在的问题及其对策

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南方农业 2024年第10期18卷 168-171页

作者：丘斌广东省乐昌林场(广东后洞森林公园管理处) 广东乐昌512200

加快造林绿化进程,提高森林植被覆盖率是森林管护的重要任务,关乎我国生态文明建设。为促进森林资源可持续开发和利用,总结森林管护的意义,分析当前广东省乐昌林场森林管护中存在的问题,提出明确职责,健全管护责任机制;创新方法,建立健... 详细信息

加快造林绿化进程,提高森林植被覆盖率是森林管护的重要任务,关乎我国生态文明建设。为促进森林资源可持续开发和利用,总结森林管护的意义,分析当前广东省乐昌林场森林管护中存在的问题,提出明确职责,健全管护责任机制;创新方法,建立健全管理机制;组建队伍,优化管护队伍建设;完善设施,加强管护工作保障;聚焦矛盾,发展与保护相协调等对策。

关键词：森林管护生态建设管护责任管护队伍广东省乐昌林场

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中国创新模式选择:自主创新抑或技术引进?

经济研究 2024年第4期59卷 113-132页

作者：谭用邱斌叶迪綦建红南京财经大学国际经贸学院 210023 东南大学经济管理学院 210096 山东大学经济学院 250100

本文旨在探讨中国企业的创新模式选择,以及不同创新模式影响企业生产率和销售绩效的供给侧与需求侧机制。本文采用全国创新调查企业数据库,在展现不同创新模式异质性影响的典型事实基础上,将创新模式融入异质性企业贸易模型,进一步采用... 详细信息

本文旨在探讨中国企业的创新模式选择,以及不同创新模式影响企业生产率和销售绩效的供给侧与需求侧机制。本文采用全国创新调查企业数据库,在展现不同创新模式异质性影响的典型事实基础上,将创新模式融入异质性企业贸易模型,进一步采用结构式估计和反事实研究,讨论企业创新模式选择所带来的生产率和国内外销售额变化。结果发现,创新将通过供给侧与需求侧机制共同影响企业生产率与国内外销售绩效,而不同创新模式的影响渠道存在显著的异质性:相比于引进国外技术,自主创新对生产率的促进作用更加明显;相比于自主创新,直接引进国外技术将在出口市场产生更大的信号效应;提高中国专利的国际认可度将有效促进企业自主创新意愿,并增加出口总量;畅通国内大循环,降低国内贸易成本,可有效抵消“卡脖子”问题对中国企业创新绩效的负面影响。

关键词：创新模式选择自主创新国外技术引进信号效应结构式估计