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Simulation Based Energy-resource Efficient Manufacturing Integrated with In-process Virtual Management

Chinese Journal of Mechanical Engineering 2016年第6期29卷 1083-1089页

作者： KATCHASUWANMANEE Kanet CHENG Kai bateman richard College of Engineering Design and Physical Sciences Brunel University Faculty of Engineering Environment and Computing Coventry University

As energy efficiency is one of the key essentials towards sustainability, the development of an energy-resource efficient manufacturing system is among the great challenges facing the current industry. Meanwhile, the availability of advanced technological innovation has created more complex manufacturing systems that involve a large variety of processes and machines serving different functions. To extend the limited knowledge on energy-efficient scheduling, the research presented in this paper attempts to model the production schedule at an operation process by considering the balance of energy consumption reduction in production, production work flow （productivity） and quality. An innovative systematic approach to manufacturing energy-resource efficiency is proposed with the virtual simulation as a predictive modelling enabler, which provides real-time manufacturing monitoring, virtual displays and decision-makings and consequentially an analytical and multidimensional correlation analysis on interdependent relationships among energy consumption, work flow and quality errors. The regression analysis results demonstrate positive relationships between the work flow and quality errors and the work flow and energy consumption. When production scheduling is controlled through optimization of work flow, quality errors and overall energy consumption, the energy-resource efficiency can be achieved in the production. Together, this proposed multidimensional modelling and analysis approach provides optimal conditions for the production scheduling at the manufacturing system by taking account of production quality, energy consumption and resource efficiency, which can lead to the key competitive advantages and sustainability of the system operations in the industry.

关键词： energy-resource efficient manufacturing virtual manufacturing manufacturing simulation in-process virtual management

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Smart Cutting Tools and Smart Machining: Development Approaches, and Their Implementation and Application Perspectives

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Chinese Journal of Mechanical Engineering 2017年第5期30卷 1162-1176页

作者： Kai Cheng Zhi-Chao Niu Robin C.Wang richard Rakowski richard bateman College of Engineering Design and Physical SciencesBrunel University London

Smart machining has tremendous potential and is becoming one of new generation high value precision manufacturing technologies in line with the advance of Industry 4.0 concepts. This paper presents some innovative design concepts and, in particular, the development of four types of smart cutting tools, including a force-based smart cutting tool, a temperature-based internally-cooled cutting tool, a fast tool servo （FTS） and smart collets for ultra- precision and micro manufacturing purposes. Implemen- tation and application perspectives of these smart cutting tools are explored and discussed particularly for smart machining against a number of industrial application requirements. They are contamination-free machining, machining of tool-wear-prone Si-based infra-red devices and medical applications, high speed micro milling and micro drilling, etc. Furthermore, implementation tech- niques are presented focusing on：（a） plug-and-produce design principle and the associated smart control algo- rithms, （b） piezoelectric film and surface acoustic wave transducers to measure cutting forces in process, （c） critical cutting temperature control in real-time machining, （d） in- process calibration through machining trials, （e） FE-based design and analysis of smart cutting tools, and （f） applica- tion exemplars on adaptive smart machining.

关键词： Smart cutting tool Smart machining Fast toolservo (FFS) Precision machining Micro manufacturing Smart tooling

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e-Manufacturing:Characteristics,applications and potentials

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Progress in Natural Science:Materials International 2008年第11期18卷 1323-1328页

作者： richard J.bateman Advanced Manufacturing & Enterprise Engineering(AMEE) School of Engineering and DesignBrunel UniversityUxbridgeMiddlesex UB8 3PHUK

In this paper,an engineering oriented approach is proposed towards e-manufacturing and its *** characteristics and potential of e-manufacturing are presented with a number of application examples developed by the authors’ research *** advances in e-manufacturing and applications are also highlighted and critically *** paper concludes with a further discussion on the promises and impact of e-manufacturing technology and philosophy on modern manufacturing industry and the practices.

关键词： e-manufacturing e-design Global manufacturing Agile manufacturing Digital manufacturing

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Pension reform:Australia and China compared

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Economic and Political Studies 2017年第4期5卷 456-474页

作者： Hazel bateman Kevin Liu School of Risk and Actuarial Studies UNSW SydneySydneyAustralia

Over the past few decades,China’s pension system has evolved from separate schemes almost exclusively for urban and public sector workers to one with broad national *** a similar time-frame,successive Australian governments have introduced reforms to Australia’s retirement income arrangements in an attempt to increase retirement savings and address age-related pressures on the financing of the publicly provided age *** paper compares,contrasts and assesses the pension systems in China and *** China and Australia are at different stages of economic development and demographic transition and operate quite different pension systems,there are lessons to be learned from each other.

关键词： Pension reform China Australia population ageing

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A 2D finite volume model for bebris flow and its application to events occurred in the Eastern Pyrenees

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International Journal of Sediment Research 2008年第4期23卷 348-360页

作者： V.MEDINA A.bateman M.HüRLIMANN Sediment Transport Research Group Department of Engineering Hydraulic Marine and Environmental Engineering Technical University of Catalonia (UPC)Jordi Girona 1-3 08034 Barcelona SpainPh.D student Sediment Transport Research Group Department of Engineering Hydraulic Marine and Environmental Engineering Technical University of Catalonia (UPC)Jordi Girona 1-3 08034 Barcelona SpainAssociate Prof. Department of Geotechnical Engineering and Geosciences Technical University of Catalonia (UPC)Jordi Girona 1-3 08034 Barcelona SpainAssociate Prof.

FLATModel is a 2D finite volume code that contains several original approaches to improve debris-flow simulation. Firstly, FLATModel incorporates a "stop-and-go" technique in each cell to allow continuous collapses and remobilizations of the debris-flow mass. Secondly, flow velocity and consequently yield stress is directly associated with the type of rheology to improve boundary accuracy. Thirdly, a simple approach for entrainment is also included in the model to analyse the effect of basal erosion of debris flows. FLATMODEL was tested at several events that occurred in the Eastern Pyrenees and simulation results indicated that the model can represent rather well the different characteristics observed in the field.

关键词： Numerical modelling Finite volume Debris flow Stop-and-go Entrainment

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Does urbanization influence the diet of a large snake？

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Current Zoology 2018年第3期64卷 311-318页

作者： Ashleigh K. WOLFE Philip W. bateman Patricia A. FLEMING Department of Environment and Agriculture Curtin University Perth Bentley WA 6102 Australia School of Veterinary and Life Sciences Murdoch University Perth Murdoch WA 6150 Australia

Urbanization facilitates synanthropic species such as rodents, which benefit the diets of many predators in cities. We investigated how urbanization affects the feeding ecology of dugites Pseudonaja affi- nis, a common elapid snake in south-west Western Australia. We predicted that urban snakes： 1） more frequently contain prey and eat larger meals, 2） eat proportionally more non-native prey, 3） eat a lower diversity of prey species, and 4） are relatively heavier, than non-urban dugites. We analyzed the diet of 453 specimens obtained from the Western Australian Museum and opportunistic road-kill collections. Correcting for size, sex, season, and temporal biases, we tested whether location influenced diet for our 4 predictions. Body size was a strong predictor of diet （larger snakes had larger prey present, a greater number of prey items, and a greater diversity of prey）. We identified potential collection biases： urban dugites were relatively smaller （snout-vent length） than non-urban specimens, and females were relatively lighter than males. Accounting for these effects, urban snakes were less likely to have prey present in their stomachs and were relatively lighter than non-urban snakes. Other urban-adapted carnivores appear to benefit from urbanization through increased food supplementation, but we found the opposite of this： urban dugites were less likely to contain a meal, and their meals were smaller, indicating they did not make greater use of synanthropic species than was evident for non-urban snakes. In contrast to other carnivores, snakes do not appear to fit a consistent directional pattern for size differences between urban and non-urban populations.

关键词： adaptation dissection feeding ecology reptile.

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Elucidating the Degradation Pathways of Human Insulin in the Solid State

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Journal of Analysis and Testing 2024年第3期8卷 288-299页

作者： Andrew Fagan Lorraine M.bateman Joseph P.O’Shea Abina M.Crean SSPC the SFI Centre for Pharmaceutical ResearchSchool of PharmacyUniversity College CorkCork T12 YT20Ireland School of Pharmacy University College CorkCork T12 YT20Ireland Analytical and Biological Chemistry Research Facility(ABCRF) University College CorkCork T12 YN60Ireland School of Chemistry University College CorkCork T12 YN60Ireland

While there have been significant advances in the development of peptide oral dosage forms in recent years,highlighted by the clinical and commercial success of approved peptides such as Rybelsus®,there remain several barriers in the way of broad range applicability of this approach to peptide *** such barrier includes the poor physical and chemical stability inherent to their structures,which persists in the solid state although degradation typically occurs at different rates and via different pathways in comparison to the solution *** insulin as a model peptide,this work sought to contribute to the development of analytical techniques for investigating common insulin degradation *** denatured,deamidated and aggregated samples were prepared and used to benchmark circular dichroism spectroscopy,reverse phase HPLC and size exclusion chromatography methods for the investigation of unfolding,chemical modifications and covalent aggregation of the insulin molecule *** state degraded samples were prepared by heating insulin powder at 60°C and 75%relative humidity for 1,3,5 and 7 d,and the degradation profiles of the samples were evaluated and compared with those observed in *** no unfolding was observed to occur,significant deamidation and covalent aggregation were *** disulfide bond cleavage using dithiothreitol allowed for separation of the insulin A-and B-chains,offering a facile yet novel means of assessing the mechanisms of deamidation and covalent aggregation occurring in the solid state.

关键词： Insulin Stability Solid state Deamidation Covalent aggregation Disulfide cleavage Biopharmaceutical analysis

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Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus

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World Journal of Gastroenterology 2013年第48期19卷 9282-9293页

作者： Fergus Noble Luke Nolan Adrian C bateman James P Byrne Jamie J Kelly Ian S Bailey Donna M Sharland Charlotte N Rees Timothy J Iveson Tim J Underwood Andrew R bateman Cancer Sciences Unit Faculty of Medicine University of Southampton Southampton SO16 6YD United Kingdom Department of Surgery University Hospital Southampton NHS Foundation Trust Southampton SO16 6YD United Kingdom Department of Cellular Pathology University Hospital Southampton NHS Foundation Trust Southampton SO16 6YD United Kingdom Cancer Care University Hospital Southampton NHS Foundation Trust Southampton SO16 6YD United Kingdom

AIM:To assess tumour regression grade(TRG)and lymph node downstaging to help define patients who benefit from neoadjuvant ***:Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal junction treated with surgery alone or neoadjuvant chemotherapy and surgery between 2005and 2011 at a single institution were *** neoadjuvant chemotherapy consisting of platinum,fluoropyrimidine and anthracycline was considered for operable patients(World Health Organization performance status≤2)with clinical stage T2-4 *** to neoadjuvant chemotherapy(NAC)was assessed using TRG,as described by Mandard et *** addition lymph node downstaging was also *** node downstaging was defined by cN1 at diagnosis:assessed radiologically(computed tomography,positron emission tomography,endoscopic ultrasonography),then pathologically recorded as N0 after surgery;ypN0 if NAC given prior to surgery,or pN0if surgery *** were followed up for 5 years post *** was defined radiologically,with or without pathological *** association was examined between t TRG and lymph node downstaging with disease free survival(DFS)and a comprehensive range of clinicopathological ***:Two hundred and eighteen patients underwent esophageal resection during the study interval with a mean follow up of 3 years(median follow up:2.552,95%CI:2.022-3.081).There was a 1.8%(n=4)inpatient mortality *** hundred and thirty-six(62.4%)patients received NAC,with 74.3%(n=101)of patients demonstrating some signs of pathological tumour regression(TRG 1-4)and 5.9%(n=8)having a complete pathological *** four point one percent(n=60)had downstaging of their nodal disease(cN1 to ypN0),compared to only 15.9%(n=13)that underwent surgery alone(pre-operatively overstaged:cN1 to pN0),(P<0.0001).Response to NAC was associated with significantly increased DFS(mean DFS;TRG 1-2:5.1years,

关键词： Esophageal cancer Gastro-esophageal cancer Neoadjuvant Regression

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Management : competing in the new era / Thomas S. bateman, Scott A. Snell. 5th ed.

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2002年

作者： Thomas S. bateman, Scott A. Snell.

来源：畅想之星图书光盘版（南... 评论

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Lubiprostone vs Senna in postoperative orthopedic surgery patients with opioid-induced constipation:A double-blind,active-comparator trial

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World Journal of Gastroenterology 2014年第43期20卷 16323-16333页

作者： Christina M Marciniak Santiago Toledo Jungwhalia Lee Michael Jesselson Jillian bateman Benjamin Grover Joy Tierny Department of Physical Medicine and Rehabilitation School of MedicineNorthwestern UniversityChicagoIL 60611United States Department of Preventive Medicine Feinberg School of MedicineNorthwestern UniversityChicagoIL 60611United States University of Chicago Medical Center ChicagoIL 60637United States The Rehabilitation Institute of Chicago ChicagoIL 60611United States Chicago College of Osteopathic Medicine ChicagoIL 60515United States

AIM: To investigate the efficacy of lubiprostone compared to Senna on bowel symptoms and constipation in post-operative orthopedic patients treated with opioids.

关键词： Constipation Opioids Lubiprostone Senna Orthopedics Rehabilitation

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