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Robust interface and excellent as-built mechanical properties of Ti–6Al–4V fabricated through laser-aided additive manufacturing with powder and wire

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 154-168页

作者： Fei weng Guijun Bi Youxiang Chew Shang Sui Chaolin Tan Zhenglin Du Jinlong Su Fern Lan Ng Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationShandong Engineering&Technology Research Center for Superhard MaterialSchool of Materials Science and EngineeringShandong UniversityJinan 250061China Institute of Intelligent Manufacturing Guangdong Academy of SciencesGuangzhou 510095China Singapore Institute of Manufacturing Technology 5 Cleantech Loop636732Singapore

The feasibility of manufacturing Ti-6Al-4V samples through a combination of laser-aided additive manufacturing with powder(LAAM_(p))and wire(LAAM_(w))was explored.A process study was first conducted to successfully circumvent defects in Ti-6Al-4V deposits for LAAM_(p) and LAAM_(w),*** the optimized process parameters,robust interfaces were achieved between powder/wire deposits and the forged substrate,as well as between powder and wire *** characterization results revealed the epitaxial prior β grains in the deposited Ti-6Al-4V,wherein the powder deposit was dominated by a finerα′microstructure and the wire deposit was characterized by lamellar α *** mechanisms of microstructure formation and correlation with mechanical behavior were analyzed and *** mechanical properties of the interfacial samples can meet the requirements of the relevant Aerospace Material Specifications(AMS 6932)even without post heat *** fracture occurred within the interfacial area,further suggesting the robust *** findings of this study highlighted the feasibility of combining LAAM_(p) and LAAM_(w) in the direct manufacturing of Ti-6Al-4V parts in accordance with the required dimensional resolution and deposition rate,together with sound strength and ductility balance in the as-built condition.

关键词： laser-aided additive manufacturing powder deposition wire deposition interfacial characteristic mechanical behavior

Binary organic nanoparticles with enhanced reactive oxygen species generation capability for photodynamic therapy

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Journal of Innovative Optical Health Sciences 2021年第3期4卷 52-59页

作者： Xiaofu weng Zhouzhou bao Xunbin Wei School of Biomedical Engineering Shanghai Jiao Tong University Shanghai 200030P.R.China Department of Obstetrics and Gynecology Ren Ji Hospital School of Medicine Shanghai Jiao Tong UniversityShanghai 200127P.R.China Shanghai Key Laboratory of Gynecologic Oncology Ren Ji Hospital School of Medicine Shanghai Jiao Tong UniversityShanghai 200127P.R.China

Photodynamic therapy(PDT)takes advantage of photosensitizers(PSs)to generate reactive oxygen species(ROS)for cell killing when excited by *** has been widely used in clinic for therapy of multiple ***,all the FDA-approved PSs,including porphyrin,are all small organic molecules,suffering from aggregation-caused quenching(ACQ)issues in biological environment and lacking tumor targeting ***(NPs)with size between 20 nm and 200 nm possess tumor targeting capability due to the enhanced permeability and retention(EPR)*** is urgent to develop a new strategy to form clinical-approved-PSs-based NPs with improved ROS generation *** this study,we report a strategy to overwhelm the ACQ of porphyrin by doping it with a type of aggregation-induced emission(AIE)luminogen to produce a binary NPs with high biocompatibility,and enhanced fluorescence and ROS generation *** NPs can be readily synthesized by mixing a porphyrin derivative,Ce6 with a typical AIE luminogen,***,our experimental results have demonstrated the feasibility and effectiveness of this strategy,endowing it a great potential in clinical applications.

关键词： Aggregation-induced emission photodynamic therapy organic nanoparticles

Track-position and vibration control simulation for strut of the Stewart platform

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2013年第4期14卷 281-291页

作者： Zhao-dong XU Chen-hui weng MOE Key Laboratory of C&PC Structures Southeast University Guangzhou Design Institute

Vibrations inherently generated by on-board disturbance sources degrade the performance of the instruments in an on-orbit spacecraft,which have stringent accuracy *** Stewart platform enables both track-positioning and vibration *** strut of the Stewart platform is designed as a piezoelectric(PZT) element in series with a voice coil motor(VCM) element and a viscoelastic *** track-positioning system uses a VCM as the main positioning control driver and a PZT as the positioning *** vibration control system uses the characteristics of struts including active and passive control elements to attenuate the *** results indicate that the Stewart platform with the designed struts has good performance in tracking and vibration attenuation with different interference waves.

关键词： Stewart platform Track-positioning control Vibration control

Extracting compressive stress-strain curve based on stick-slip shear banding process in bulk metallic glasses

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Journal of Iron and Steel Research International 2017年第4期24卷 372-377页

作者： Jing Hu Yun-xuan weng Xiao-li Li bao-an Sun School of Material and Mechanical Engineering Beijing Technology and Business University Herbert Gleiter Institute of Nanoscience Nanjing University of Science & Technology

Based on the stick-slip process,an effective method to extract the stress-strain curve directly from the crosshead displacement-load raw data in compression of bulk metallic glasses was *** method was tested in two bulk metallic glass samples with different plasticities and shear band *** extracted stress-strain curves were found to well resemble the stress-strain curve measured by a laser *** addition,the extracted curve could resolve fine structures of serrated flow much better than that measured by extensometer,thus facilitating the study of shear banding *** obtained by this method made the stick-slip dynamics of shear banding valid,and this method could be employed to obtain the real strain of small-sized metallic glass samples where extensometer cannot be applied.

关键词： Serrated flow Shear banding Stick-slip Stress-strain curve

Artificial bee colony algorithm with comprehensive search mechanism for numerical optimization

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Journal of Systems Engineering and Electronics 2015年第3期26卷 603-617页

作者： Mudong Li hui Zhao Xingwei weng Hanqiao Huang Department of Aeronautics and Astronautics Engineering Air Force Engineering University

The artificial bee colony （ABC） algorithm is a sim- ple and effective global optimization algorithm which has been successfully applied in practical optimization problems of various fields. However, the algorithm is still insufficient in balancing ex- ploration and exploitation. To solve this problem, we put forward an improved algorithm with a comprehensive search mechanism. The search mechanism contains three main strategies. Firstly, the heuristic Gaussian search strategy composed of three different search equations is proposed for the employed bees, which fully utilizes and balances the exploration and exploitation of the three different search equations by introducing the selectivity probability P,. Secondly, in order to improve the search accuracy, we propose the Gbest-guided neighborhood search strategy for onlooker bees to improve the exploitation performance of ABC. Thirdly, the self- adaptive population perturbation strategy for the current colony is used by random perturbation or Gaussian perturbation to en- hance the diversity of the population. In addition, to improve the quality of the initial population, we introduce the chaotic opposition- based learning method for initialization. The experimental results and Wilcoxon signed ranks test based on 27 benchmark func- tions show that the proposed algorithm, especially for solving high dimensional and complex function optimization problems, has a higher convergence speed and search precision than ABC and three other current ABC-based algorithms.

关键词： artificial bee colony (ABC) function optimization,search strategy population initialization Wilcoxon signed ranks test.

The changes in the geographical patterns of China’s tourism in 1978–2018:Characteristics and underlying factors

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Journal of Geographical Sciences 2020年第3期30卷 487-507页

作者： ZHANG Chengming weng Shixiu bao Jigang School of Geography and Planning Sun Yat-sen UniversityGuangzhou 510275China School of Tourism Management Sun Yat-sen UniversityGuangzhou 510275China Center for Tourism Planning&Research Sun Yat-sen UniversityGuangzhou 510275China

Since the reform and opening-up policy launched in 1978,the number of inbound tourists increased from 1.8 million in 1978 to 139.5 million in 2017,and that of domestic tourists increased from 344 million in 1991 to 5 billion in *** article conducts research on how the geographical pattern of China’s tourism has evolved in the last four decades on the national-scale and regional-scale,for rare studies before could focus on such an extended date and utilize inbound and domestic tourism data *** on viable datasets and multiple vibrant data analysis approaches(including the Gini coefficient,primacy index analysis,hot spot analysis and Pearson correlation analysis),this article unpacks triple vital realities.(1)The overall geographical pattern of China’s tourism development can arguably summarize as“high in the eastern and low in the western part,high in the southern and low in the northern part.”Meanwhile,China’s inbound tourism has long shown a pattern of polarized distribution;While,domestic tourism has experienced a shift from the polarized distribution to the equilibrium distribution.(2)According to the features and characteristics,China's tourism development can be divided into four *** are precisely the initial modern tourism stage(1978–1988),the domestic tourism cultivating stage(1989–1996),the rapid development stage(1997–2007)and the new normal stage(2008–present).(3)This article also identified multiple factors underlying the inbound and domestic tourism development in China,including policies,management systems,tourism demand,tourist attractions,economic level,consumption level,industrial development,investment status,traffic conditions,accommodation services,intermediary services and degree of openness.

关键词： reform and opening-up tourism development spatial pattern development stage influencing factor China

Heterogeneity of mature oligodendrocytes in the central nervous system

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Neural Regeneration Research 2025年第5期20卷 1336-1349页

作者： Chao weng Adam M.R.Groh Moein Yaqubi Qiao-Ling Cui Jo Anne Stratton G.R.Wayne Moore Jack P.Antel Neuroimmunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous *** evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to *** the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is *** delve into early 20th-century studies by Robertson and Río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature ***,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination ***,modern molecular investigations,employing techniques such as single cell/nucleus RNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system *** and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric ***,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined *** studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte *** research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,

关键词： aging central nervous system diseases electron microscopy heterogeneity immunohistochemistry myelin sheath natural history neuroglia oligodendroglia single-cell gene expression analysis

Innate immunity against malaria parasites in Anopheles gambiae

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Insect Science 2008年第1期15卷 45-52页

作者： Yang Chen Zhi-hui weng Liangbiao Zheng Shanghai Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 300 Fenglin Road ShanghaL China

Malaria continues to exert a huge toll in the world today, causing approximately 400 million cases and killing between 1-2 million people annually. Most of the malaria burden is borne by countries in Africa. For this reason, the major vector for malaria in this continent, Anopheles gambiae, is under intense study. With the completion of the draft sequence of this important vector, efforts are underway to develop novel control strategies. One promising area is to harness the power of the innate immunity of this mosquito species to block the transmission of the malaria parasites. Recent studies have demonstrated that Toll and Imd signaling pathways and other immunity-related genes （encoding proteins possibly function in recognition or as effector molecules） play significant roles in two different arms of innate immunity： level of infection intensity and melanization of Plasmodium oocysts. The challenges in the future are to understand how the functions of these different genes are coordinated in defense against malaria parasites, and if different arms of innate immunity are cross-regulated or coordinated.

关键词： Anopheles immunity infection intensity malaria melanization

Pseudo-Bonding Interaction between Boron-doped Heterofullerene and Zinc Porphine Predicted by DFT Calculation

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Chinese Journal of Chemical Physics 2014年第3期27卷 285-290页

作者： Jun-ying weng Ting-ting Zhou Ying-hui Zhang Chemistry Department Nankai University Tianjin 300071 China

Theoretical study on the supramolecular complexes formed between boron-doped het- erofullerene （C59B） and zinc porphine （ZnF）, namely C59B-ZnP and its anion species C59B-ZnP, was performed by density functional theory calculation at wB97XD/6-31G（d） level. Strong interaction between porphyrin and heterofullerene moiety was predicted for these complexes based on geometry and electronic structure analysis. Especially, pseudobonding interaction occurring between the B atom of fullerene and the N atom of porphyrin was predicted to occur in C59B-ZnP complex, but be broken in C59B-ZnP complex. Time-dependent density functional theory calculation manifests the redshift of electron absorption for ZnP upon the interaction with heterofullerene.

关键词： Boron-doped fullerene Zinc porphine Supramolecular complex DFT calculation