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巴旦木粉葛代餐饼干的配方优化及降糖活性

食品工业 2024年第3期45卷 62-67页

作者：敬思群黄淑芳梁苑锟于白音韶关学院食品学院韶关512005

以感官评分、硬度、DPPH·自由基清除率、ABTS^(+)·自由基清除率、总抗氧化能力、α-葡萄糖苷酶抑制活性为考察指标,分析巴旦木粕粉、粉葛全粉、低聚木糖添加量对巴旦木粉葛代餐饼干品质的影响。在单因素试验基础上,以综合评分为响应值... 详细信息

以感官评分、硬度、DPPH·自由基清除率、ABTS^(+)·自由基清除率、总抗氧化能力、α-葡萄糖苷酶抑制活性为考察指标,分析巴旦木粕粉、粉葛全粉、低聚木糖添加量对巴旦木粉葛代餐饼干品质的影响。在单因素试验基础上,以综合评分为响应值,采用三因素三水平的响应面分析法确定饼干的最优配方;建立高糖饲料诱导果蝇2型糖尿病模型,以总蛋白含量、甘油三酯含量、海藻糖含量为考察指标,研究巴旦木粉葛代餐饼干的降糖活性。结果表明,巴旦木粉葛代餐饼干的最优配方为巴旦木粕粉25%,粉葛全粉30%,低聚木糖2.5%,低筋面粉40%,玉米淀粉10%,水48%,玉米胚芽油14%,食盐1.5%,双效泡打粉1.0%,磷酸氢钠0.7%。巴旦木粉葛代餐饼干清除DPPH·自由基能力为8.470±0.819 mg/mL,清除ABTS^(+)·自由基能力为5.235±0.265 mg/mL,总抗氧化能力为0.184,巴旦木粉葛代餐饼干有一定抗氧化活性。体外降糖试验及果蝇生存试验表明,巴旦木粉葛代餐饼干具有降糖作用。

关键词：巴旦木粕粉-粉葛全粉代餐饼干最优配方响应面法果蝇2型糖尿病模型

基于网络药理学及分子对接探讨菊花抗炎的作用机制

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韶关学院学报 2024年第6期45卷 6-13页

作者：洪梦杰于白音柏超凡张朝玉刘洁连河南科技职业大学医学院河南周口466000 韶关学院广东省粤北食药资源利用与保护重点实验室广东韶关512005 韶关学院生物与农业学院广东韶关512005 南雄市乡村振兴服务中心广东南雄512400 广东华暨农业科技有限公司广东韶关512000

基于网络药理学和分子对接验证方法探讨菊花抗炎的作用机制.先从TCMSP数据库筛选17个菊花活性成分和109个对应靶点,再从GeneCards、NCBI、OMIM和DisGeNET数据库筛选出2492个炎症靶点;然后将菊花活性成分靶点和炎症靶点取交集得到菊花抗... 详细信息

基于网络药理学和分子对接验证方法探讨菊花抗炎的作用机制.先从TCMSP数据库筛选17个菊花活性成分和109个对应靶点,再从GeneCards、NCBI、OMIM和DisGeNET数据库筛选出2492个炎症靶点;然后将菊花活性成分靶点和炎症靶点取交集得到菊花抗炎的潜在靶点;再通过构建潜在靶点PPI网络并进行拓扑分析得到菊花抗炎的核心靶点;并利用DAVID数据库对核心靶点进行GO和KEGG富集分析后,利用Cytoscape 3.9.1软件构建“活性成分-核心靶点-通路”网络并进行拓扑分析,得到菊花抗炎的关键成分和关键靶点;最后运用AutoDock Vina对菊花抗炎的关键成分和关键靶点进行分子对接验证,根据对接结合能利用Origin软件绘制热图,分析结合能大小.结果表明,基于网络药理学,共筛选到菊花抗炎潜在靶点56个;再经PPI网络拓扑分析得到菊花抗炎的核心靶点21个;核心靶点经富集分析及“活性成分-核心靶点-通路”网络拓扑分析,最终得到菊花抗炎的9个关键成分和9个关键靶点;分子对接验证结果显示,菊花抗炎的关键活性成分和关键靶点结合良好,构象稳定.

关键词：菊花炎症网络药理学分子对接

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大桥虎耳草叶柄离体培养与植株再生

植物生理学报 2022年第12期58卷 2286-2294页

作者：韩伟唐光大包英华于白音韶关学院英东生物与农业学院广东韶关512005 华南农业大学林学与风景园林学院广州510642

以大桥虎耳草(Saxifraga daqiaoensis)的叶柄为外植体,研究了HgCl_(2)表面消毒时间及植物生长调节剂对其愈伤组织诱导、分化、芽增殖及生根培养的影响,建立离体培养和植株再生体系。结果表明,大桥虎耳草叶柄适宜的消毒条件为75%酒精消毒... 详细信息

以大桥虎耳草(Saxifraga daqiaoensis)的叶柄为外植体,研究了HgCl_(2)表面消毒时间及植物生长调节剂对其愈伤组织诱导、分化、芽增殖及生根培养的影响,建立离体培养和植株再生体系。结果表明,大桥虎耳草叶柄适宜的消毒条件为75%酒精消毒30 s+0.1%HgCl_(2)消毒8~10 min;愈伤组织诱导的培养基为1/2MS+6-BA 1 mg·L^(-1)+NAA 1 mg·L^(-1)+PVP 2 g·L^(-1),诱导率达到84.26%;分化培养基为1/2MS+6-BA 1mg·L^(-1)+NAA 0.2 mg·L^(-1)+PVP 2 g·L^(-1),分化率为84.48%;芽增殖培养基为1/2MS+6-BA 2 mg·L^(-1)+NAA 0.2mg·L^(-1),芽增殖率为84.60%;生根培养基为1/2MS+IBA 0.5 mg·L^(-1),生根率可达100%,单株生根数为5~10。实验结果将为大桥虎耳草种质资源的保存和种苗繁育提供技术参考。

关键词：大桥虎耳草愈伤组织诱导分化芽增殖生根

Linear-Quadratic Pareto Cooperative Game for Mean-Field Backward Stochastic System

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Journal of Systems Science & Complexity 2024年第3期37卷 947-964页

作者： WANG yu School of Control Science and Engineering Shandong UniversityJinan 250061China

This paper focuses on a Pareto cooperative differential game with a linear mean-field backward stochastic system and a quadratic form cost functional. Based on a weighted sum optimality method, the Pareto game is equivalently converted to an optimal control problem. In the first place,the feedback form of Pareto optimal strategy is derived by virtue of decoupling technology, which is represented by four Riccati equations, a mean-field forward stochastic differential equation(MF-FSDE),and a mean-field backward stochastic differential equation(MF-BSDE). In addition, the corresponding Pareto optimal solution is further obtained. Finally, the author solves a problem in mathematical finance to illustrate the application of the theoretical results.

关键词： Backward stochastic differential equation linear-quadratic control mean-field Pareto optimality

Topological Stability and Entropy for Certain Set-valued Maps

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Acta Mathematica Sinica,English Series 2024年第4期40卷 962-984页

作者： yu ZHANG yu Jun ZHU School of Mathematical Sciences Xiamen UniversityXiamen 361005P.R.China

In this paper,the dynamics(including shadowing property,expansiveness,topological stability and entropy)of several types of upper semi-continuous set-valued maps are mainly considered from differentiable dynamical systems points of *** is shown that(1)if f is a hyperbolic endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has theε-shadowing property,and moreover,if f is an expanding endomorphism then there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has the Lipschitz shadowing property;(2)when a set-valued map F is generated by finite expanding endomorphisms,it has the shadowing property,and moreover,if the collection of the generators has no coincidence point then F is expansive and hence is topologically stable;(3)if f is an expanding endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that h(F_(f,U,ε))=h(f);(4)when F is generated by finite expanding endomorphisms with no coincidence point,the entropy formula of F is ***,the dynamics of the set-valued maps based on discontinuous maps on the interval are also considered.

关键词： Set-valued map orbit space hyperbolic endomorphism perturbation shadowing expansiveness topological stability entropy

A new liquid membrane diffusion model for characterizing the adsorption kinetics of europium by using a continuous measurement of adsorption platform

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Nuclear Science and Techniques 2024年第1期35卷 59-72页

作者： Hao-Qi yu Tao yu Jian-Hua Ye State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China CGN Cangnan Nuclear Power Co. Ltd.Cangnan 325800China Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices East China University of TechnologyNanchang 330013China School of Nuclear Science and Engineering East China University of TechnologyNanchang 330013China

To explore the kinetic adsorption under continuous and nonequilibrium states, an integration of continuous measurement and adsorption platform kinetics method was proposed, which was initially called the ICM-AP kinetics method, and a corresponding kinetic adsorption experimental method was developed. Adsorption experiments of europium(Eu) on Ca-bentonite,Na-bentonite, and the D231 cation exchange resin were performed using the ICM-AP kinetics method and continuous measurements. Because the kinetic experimental results observed in this study were different from those of traditional batch adsorption data, pseudo-first-order or pseudo-second-order kinetic models were unsuitable for fitting the experimental ***, a liquid membrane diffusion(LMD) model was developed based on the assumption of simultaneous adsorption/desorption to discuss the mechanism of kinetic adsorption. The kinetic adsorption mechanism was also studied by using *** results indicated that the proposed adsorption model can fit the experimental data more suitably, and the adsorption/desorption behaviors of Eu on bentonite and the D231 resin were simultaneously observed, suggesting that the adsorption kinetics of Eu(Ⅲ) was mainly dominated by hydrated Eu(Ⅲ) ions on the liquid membrane.

关键词： ICM-AP method LMD model Adsorption mechanism Eu(Ⅲ)

Device design principles and bioelectronic applications for flexible organic electrochemical transistors

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International Journal of Extreme Manufacturing 2024年第1期6卷 126-153页

作者： Lin Gao Mengge Wu Xinge yu Junsheng yu State Key Laboratory of Electronic Thin Films and Integrated Devices School of Optoelectronic Science and EngineeringUniversity of Electronic Science and Technology of China(UESTC)Chengdu 610054People’s Republic of China Department of Biomedical Engineering City University of Hong KongHong Kong Special Administrative Region of ChinaPeople’s Republic of China

Organic electrochemical transistors(OECTs) exhibit significant potential for applications in healthcare and human-machine interfaces, due to their tunable synthesis, facile deposition, and excellent biocompatibility. Expanding OECTs to the fexible devices will significantly facilitate stable contact with the skin and enable more possible bioelectronic applications. In this work,we summarize the device physics of fexible OECTs, aiming to offer a foundational understanding and guidelines for material selection and device architecture. Particular attention is paid to the advanced manufacturing approaches, including photolithography and printing techniques, which establish a robust foundation for the commercialization and large-scale fabrication. And abundantly demonstrated examples ranging from biosensors, artificial synapses/neurons, to bioinspired nervous systems are summarized to highlight the considerable prospects of smart healthcare. In the end, the challenges and opportunities are proposed for fexible OECTs. The purpose of this review is not only to elaborate on the basic design principles of fexible OECTs, but also to act as a roadmap for further exploration of wearable OECTs in advanced bio-applications.

关键词： flexible organic electrochemical transistors wearable bioelectronics manufacturing approaches device physics neuromorphic applications

A guidance and control design with reduced information for a dual-spin stabilized projectile

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Defence Technology（防务技术） 2024年第3期33卷 494-505页

作者： yu Wang Jiyan yu Xiaoming Wang Jia Fangxiu Intelligent Ammunition Technology National Defense Key Discipline Laboratory Nanjing University of Science and TechnologyNanjingJiangsu210094China

In this paper,an integrated guidance and control method based on an adaptive path-following controller is proposed to control a spin-stabilized projectile with only translational motion information under the constraint of an actuator,uncertainties in aerodynamic parameters and measurements,and control system *** to the fairly high rotation speed,the dynamic model of this missile is strongly nonlinear,uncertain and coupled in pitch,yaw and roll channels.A theoretical equivalent resultant force and uncertainty compensation method are comprehensively used to realize decoupling of pitch and *** response to the strong nonlinear and time-varying characteristics of the dynamic system,the quasi-linear model whose parameters are obtained by interpolation of points selected as the segmentation points in the trajectory envelope,is used for calculation in each *** cope with the system uncertainty caused by model approximation,parameter uncertainty and ballistic interference,an extended state estimator is used to compensate the output feedback according to the test ballistic *** order to improve the tracking efficiency and ensure the tracking error convergence with only translational motion information,the virtual guide point,whose derivative is deduced according to the Lyapunov principle,is calculated in real time according to the projection relationship between the real-time position and the reference trajectory,and a virtual line-of-sight angle and the backstepping method are used for the design of the guidance and control *** order to avoid the influence of control input saturation on the guidance and control performance due to the actuator limitation and improve the robustness of the system,an anti-saturation compensator is designed according to the two-step *** feasibility and effectiveness of the path-following controller is verified through closed-loop flight simulations with measurement,control,and condition *** result

关键词： Spin-stabilized projectile Reduced information Path-following control Extended state observer Coupled nonlinear system Input saturation

Quantum Spin Exchange Interactions to Accelerate the Redox Kinetics in Li–S Batteries

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Nano-Micro Letters 2024年第5期16卷 370-383页

作者： yu Du Weijie Chen yu Wang yue yu Kai Guo Gan Qu Jianan Zhang Key Laboratory of Advanced Energy Catalytic and Functional Materials Preparation of Zhengzhou City College of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001People’s Republic of China

Spin-engineering with electrocatalysts have been exploited to suppress the“shuttle effect”in Li–S *** selec-tion,spin-dependent electron mobility and spin potentials in activation barriers can be optimized as quantum spin exchange interactions lead-ing to a significant reduction of the electronic repulsions in the orbitals of ***,we anchor the MgPc molecules on fluorinated carbon nanotubes(MgPc@FCNT),which exhibits the single active Mg sites with axial *** to the density functional theory calculations,the electronic spin polarization in MgPc@FCNT not only increases the adsorption energy toward LiPSs intermediates but also facilitates the tunneling process of electron in Li–S *** a result,the MgPc@FCNT provides an initial capacity of 6.1 mAh cm^(-2) even when the high sulfur loading is 4.5 mg cm^(-2),and still maintains 5.1 mAh cm^(-2) after 100 *** work provides a new perspective to extend the main group single-atom catalysts enabling high-performance Li–S batteries.

关键词： Metal phthalocyanines Spin polarization Electrocatalysis Li–S batteries