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STCF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.Z.bai Y.bai O.bakina A.barnyakov V.blinov V.bobrovnikov D.bodrov A.bogomyagkov A.bondar I.boyko Z.H.bu F.M.Cai H.Cai J.J.Cao Q.H.Cao X.Cao Z.Cao Q.Chang K.T.Chao D.Y.Chen H.Chen H.X.Chen J.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen H.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.L.Fu J.Gao Y.N.Gao P.S.Ge C.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong b.gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.b.He S.Q.He X.G.He Y.L.He Z.b.He Z.X.Heng b.L.Hou T.J.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.C.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.b.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.b.Jiang J.Jiang S.Z.Jiang J.b.Jiao Z.Jiao H.J.Jing X.L.Kang X.S.Kang b.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev C.H.Li C.Li D.Y.Li F.Li G.Li G.Li H.b.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.J.Li H.Liang J.H.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao C.X.Lin D.X.Lin X.S.Lin b.J.Liu C.W.Liu D.Liu F.Liu G.M.Liu H.b.Liu J.Liu J.J.Liu J.b.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.b.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long C.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo T.Luo X.F.Luo Y.H.Luo H.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata b.b.Qi Y.Q.Qi W.b.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin T.L.Qiu J.Rademacker C.F.Redmer H.Y.Sang Anhui University Hefei 230039China beihang University Beijing 100191China budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the bEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in China is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

Reservoir characteristics and controlling factor of tight sandstone in Shuixigou Group in Taibei depression,Turpan-Hami basin

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Energy Geoscience 2024年第2期5卷 70-80页

作者： Tong Lin Xuan Chen Fan Yang Hongguang gou Mingyu Liu Runze Yang PetroChina Research Institute of Petroleum Exploration&Development Beijing100083China Research Institute of Exploration&Development PetroChina Tuha Oilfield Company HamiXinjiang839009China China University of Geosciences(beijing) Beijing100083China

The positive structure belts surrounding the Taibei Sag,Turpan-Hami basin,have been the main targets for oil and gas exploration for years and are now left with remaining resources scattering in reservoirs adjacent to source rocks in the sag,where the Shuixigou Group with substantial oil and gas potential constitutes the primary focus for near-source ***,characterization of development and key controlling factors of reservoir space becomes a must for future exploration in the *** study investigates the development traits,genesis,and controlling factors of the Xishanyao and Sangonghe formations in the Shengbei and Qiudong Sub-sags of the Taibei Sag with techniques such as cast thin-section observation,porosity and permeability tests,high-pressure mercury injection,and saturation fluid NMR analysis of reservoir *** findings reveal that the Shuixigou Group in the Taibei Sag consists of lithic *** in the group are mostly poor in terms of physical properties,with undeveloped primary pores dominated by intergranular dissolved pores as a result of a strong *** analysis of key controlling factors of the Sangonghe Formation reveals significant distinctions in sandstone particle size,sand body thickness,genesis and distribution,provenance location,and source rock type between the Qiudong area and Shengbei ***,the coal seams of the Xishanyao Formation exhibit heightened development with shallower burial depth and lower maturity compared to those of the Sangonghe ***,this environment fosters the formation of organic acids,which have a stronger dissolution effect on minerals to develop secondary dissolution pores,and ultimately resulting in better reservoir physical ***,the reservoirs within the Qiudong area of the Taibei Sag demonstrate superior characteristics compared to those in the Shengbei ***,the reservoir physical properties of the Xishanyao For

关键词： Intergranular dissolved pore Organic acid dissolution Secondary dissolution pore Tight sandstone Shuixigou group Turpan-Hami basin

bioceramic scaffolds with two-step internal/external modification of copper-containing polydopamine enhance antibacterial and alveolar bone regeneration capability

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Journal of Zhejiang University-Science b(biomedicine & biotechnology) 2024年第1期25卷 65-82页

作者： Xiaojian JIANG Lihong LEI Weilian SUN Yingming WEI Jiayin HAN Shuaiqi ZHONG Xianyan YANG Zhongru gou Lili CHEN Department of Oral Medicine the Second Affiliated HospitalZhejiang University School of MedicineHangzhou310009China bio-nanomaterials and Regenerative Medicine Research Division Zhejiang–California International Nanosystem InstituteZhejiang UniversityHangzhou310058China

Magnesium-doped calcium silicate(CS)bioceramic scaffolds have unique advantages in mandibular defect repair;however,they lack antibacterial properties to cope with the complex oral ***,for the first time,the CS scaffold was functionally modified with a novel copper-containing polydopamine(PDA(Cu^(2+)))rapid deposition method,to construct internally modified(*P),externally modified(@PDA),and dually modified(*P@PDA)*** morphology,degradation behavior,and mechanical properties of the obtained scaffolds were evaluated in *** results showed that the CS*P@PDA had a unique micro-/nano-structural surface and appreciable mechanical *** the prolonged immersion stage,the release of copper ions from the CS*P@PDA scaffolds was rapid in the early stage and exhibited long-term sustained *** in vitro evaluation revealed that the release behavior of copper ions ascribed an excellent antibacterial effect to the CS*P@PDA,while the scaffolds retained good cytocompatibility with improved osteogenesis and angiogenesis ***,the PDA(Cu^(2+))-modified scaffolds showed effective early bone regeneration in a critical-size rabbit mandibular defect ***,it was indicated that considerable antibacterial property along with the enhancement of alveolar bone regeneration can be imparted to the scaffold by the two-step PDA(Cu^(2+))modification,and the convenience and wide applicability of this technique make it a promising strategy to avoid bacterial infections on implants.

关键词： Copper-containing polydopamine Modification Antibacterial property bone regeneration Angiogenesis bioceramic scaffold

Discovery of a potent and selective cell division cycle 7 inhibitor from 6-(3-fluoropyridin4-yl)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as an orally active antitumor agent

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Acta Pharmaceutica Sinica b 2024年第2期14卷 893-896页

作者： Mingwei Fu Min Ge Wanxiang Yang Chunchen Hu Xiaowei Li Yuanjiang Wang Shaohua gou Pharmaceutical Research Center and School of Chemistry and Chemical Engineering Southeast UniversityNanjing 211189China Jiangsu Province Hi-Tech Key Laboratory for biomedical Research Southeast UniversityNanjing 211189China Zenji Research Laboratories Nanjing 211189China

To the Editor:Kinase cell division cycle 7(CDC7),a cell division cycle protein,takes a vital role in mediating DNA ***7 complexes in the nucleus can phosphorylate the minichromosome maintenance complex(MCM)family members that bind to *** addition,CDC7 kinase,as a molecular switch regulating DNA replication,can mediate DNA damage signaling pathways to stimulate cell cycle termination as well as DNA *** have shown that CDC7 is overexpressed in many types of cancer cells,and its overexpression was related to poor patient survival,tumor grade,genetic instability,aneuploidy and so ***,CDC7 is a promising target for antitumor therapy.

关键词： Cell division cycle 7 DNA replication CDC7 inhibitor Anti-tumor

A non-viral gene therapy for melanoma by staphylococcal enterotoxin A

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Chinese Chemical Letters 2024年第5期35卷 325-329页

作者： Ling Yang Min Ren Jie Wang Liming He Shanshan Wu Shuai Yang Wei Zhao Hao Cheng Xiaoming Zhou Maling gou State Key Laboratory of biotherapy and Cancer Center West China HospitalSichuan UniversityChengdu 610041China Department of Ophthalmology West China HospitalSichuan UniversityChengdu 610041China State Key Laboratory of biotherapy Department of Integrated Traditional Chinese and Western MedicineRare Diseases CenterWest China HospitalSichuan UniversityChengdu 610041China

Staphylococcal enterotoxin A(SEA)derived from Staphylococcus aureus,as a superantigen,shows potential for cancer immunotherapy,but systemic immunotoxicity restricts its clinical *** delivery of SEA to tumor site provides a promising option for reducing the systemic ***,we constructed an iRGD peptide(H-[Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys]-NH_(2))modified nanoparticle(iDPP)to deliver plasmids encoding SEA for melanoma *** iDPP/SEA nanocomplexes efficiently mediated SEA expression in b16-F10 cells in vivo and in vitro and induced the activation of lymphocytes and maturation of murine bone marrow-derived dendritic cells(bMDCs)in *** the subcutaneous b16-F10 melanoma model,the iDPP/SEA nanocomplexes could effectively enhance immune response and T lymphocytes infiltration in tumor site after intravenous administration,thereby considerably decreased melanoma ***,no obvious adverse effect was observed after intravenous administration of the iDPP/SEA nanocomplexes in *** findings demonstrated that gene therapy of SEA is a potential candidate for melanoma treatment.

关键词： Gene therapy Superantigen Melanoma Staphylococcal enterotoxins A Immunotherapyene therapy

光学自旋角动量的调控机理及研究进展(特邀)

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光学学报 2024年第10期44卷 23-46页

作者：苟新鑫李松泽石鹏袁小聪深圳大学射频异质异构集成全国重点实验室微纳光电子学研究院纳米光子学研究中心广东深圳518060 之江实验室智能感知研究院浙江杭州311100

自旋角动量是基本粒子和场的一个基本的动力学物理量,它在光与物质相互作用中扮演着极其重要的角色。在光学研究中,光的自旋角动量与圆极化密切相关,通过研究光学自旋与物质或结构的相互作用产生了许多新颖有趣的光学现象和光学应用,并... 详细信息

自旋角动量是基本粒子和场的一个基本的动力学物理量,它在光与物质相互作用中扮演着极其重要的角色。在光学研究中,光的自旋角动量与圆极化密切相关,通过研究光学自旋与物质或结构的相互作用产生了许多新颖有趣的光学现象和光学应用,并诞生了自旋光学这一新兴学科。过去的研究中,研究人员主要聚焦在与平均波矢方向平行的纵向光学自旋。近年来,科研人员通过研究限制场如聚焦波、导波和倏逝波等的自旋轨道耦合性质,发现了一类新型的光学自旋,这类自旋与平均波矢方向垂直,因此被称为光学横向自旋。横向自旋具有自旋动量绑定的性质,一经发现便受到研究人员的广泛关注。横向自旋的发现拓展了光学自旋轨道相互作用的内容,并在光学操纵、光学精密检测、手性量子光学和光学自旋拓扑态等领域具有广阔的应用前景。本文从理论、实验技术和应用3个方面详细介绍自旋光学的最新进展。自旋光学的理论概念和框架可为研究人员进一步开拓基于光学自旋在光学成像、光学探测、光通信和量子技术等领域的应用发挥巨大的作用,同时也可拓展到一般经典波场,比如流体波、声波和引力波等。

关键词：物理光学自旋角动量自旋动量绑定自旋轨道耦合光学微分计算光学探测横向光学力

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短视频:大学生思想政治教育的有效载体

黄冈师范学院学报 2024年第3期44卷 85-90页

作者：苟艳川北医学院马克思主义学院四川南充637000

短视频是从属于微文化的新型传播媒介。短视频以其显著的优势而成为大学生思想政治教育的重要载体,是集文化载体、网络媒介载体、活动载体于一体的复合载体形式。以短视频作为大学生思想政治教育的载体面临诸多挑战,表现为短视频传播场... 详细信息

短视频是从属于微文化的新型传播媒介。短视频以其显著的优势而成为大学生思想政治教育的重要载体,是集文化载体、网络媒介载体、活动载体于一体的复合载体形式。以短视频作为大学生思想政治教育的载体面临诸多挑战,表现为短视频传播场域的复杂化与思想政治教育效果的弱化,短视频内容的“泛娱乐化”倾向与思想政治教育权威的消解,短视频传播的智能化模式与思想政治教育的主客体关系的重构。以短视频为载体开展大学生思想政治教育,需要打造思想政治教育金课,提升思想政治教育的亲和性,不断探索思想政治教育融合短视频育人模式,充分利用短视频助力思想政治教育的发展。

关键词：短视频大学生思想政治教育载体

人工智能与财政预算支出管理——基于公共卫生预算的分析

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财经论丛 2024年第7期 28-37页

作者：熊励涂诗芬苟燕楠上海大学管理学院上海200444

通过将人工智能运用于公共卫生预算分配,本文实证检验了人工智能方法在财政预算支出管理中的有效性。本文以2014—2022年广东21个地级市为研究样本,构建人工智能模型探讨公共卫生预算支出与人口死亡率、甲乙类传染病发病数量和人均地区... 详细信息

通过将人工智能运用于公共卫生预算分配,本文实证检验了人工智能方法在财政预算支出管理中的有效性。本文以2014—2022年广东21个地级市为研究样本,构建人工智能模型探讨公共卫生预算支出与人口死亡率、甲乙类传染病发病数量和人均地区生产总值等多目标的联系。研究发现:第一,提高卫生监督机构、突发公共卫生应急处理以及疾病预防控制机构预算水平是降低人口死亡率的有效途径;第二,优化基本公共卫生服务、城市社区卫生机构和老龄卫生健康事务的预算分配是控制甲乙类传染病发病数量的关键;第三,疾病预防控制机构、突发公共卫生事件应急处理和采供血机构的预算支出是保障劳动力健康和经济增长的基石;第四,控制传染病发病数量与提高人均地区生产总值存在一定程度的目标冲突,而降低人口死亡率与提高生产总值的目标则较为一致。

关键词：财政预算支出人工智能预算分配公共卫生

植被恢复边坡土壤抗蚀性及其影响因子耦合协调分析

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人民黄河 2024年第5期46卷 123-127页

作者：谢贤健苟千陶内江师范学院地理与资源科学学院四川内江641112

为了给边坡植被恢复设计等提供参考和技术支撑,基于内江市境内公路边坡经0、5、7、15、20 a植被恢复的样地野外调查资料,以土壤颗粒(团聚体)平均质量直径和水稳性指数为土壤抗蚀性指标,以土壤粒径≥0.25 mm的大团聚体含量、容重、有机... 详细信息

为了给边坡植被恢复设计等提供参考和技术支撑,基于内江市境内公路边坡经0、5、7、15、20 a植被恢复的样地野外调查资料,以土壤颗粒(团聚体)平均质量直径和水稳性指数为土壤抗蚀性指标,以土壤粒径≥0.25 mm的大团聚体含量、容重、有机质含量、碱解氮含量、速效磷含量、速效钾含量等6个土壤理化性质指标为土壤抗蚀性影响因子,采用主成分分析、耦合协调度分析等方法,探究不同植被恢复年限的边坡土壤抗蚀性与其影响因子的耦合协调关系,得到以下主要结论:1)不同植被恢复年限的土壤抗蚀性指标及其影响因子具有显著差异,随着植被恢复年限的延长,土壤大团聚体含量和养分含量呈增加趋势,土壤容重呈减小趋势,土壤抗蚀性呈增强趋势;2)碱解氮含量、有机质含量、速效磷含量、大团聚体含量、容重是不同植被恢复年限土壤抗蚀性的主要影响因子;3)土壤理化性质指标中,化学指标(速效磷含量、碱解氮含量、有机质含量、速效钾含量)对土壤抗蚀性的影响大于物理指标(大团聚体含量、容重)的影响,进行植被护坡设计时应当注重有机质和速效肥料的保持;4)土壤理化性质指标与土壤抗蚀性指标的耦合协调度随植被恢复年限的延长而提高,植被恢复15 a时二者的耦合协调类型仍属弱协调、植被恢复20 a时二者的耦合协调类型尚属中度协调,为了进一步改善边坡土壤的理化性质、促进稳定土壤结构的形成、增强土壤抗蚀性,还需更长时间的植被恢复。

关键词：土壤抗蚀性植被恢复边坡土壤理化性质耦合关联