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Antibacterial HA-coatings on bioresorbable Mg alloy

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Journal of Magnesium and Alloys 2024年第5期12卷 1965-1985页

作者： K.V.nadaraia D.V.Mashtalyar M.A.Piatkova A.I.Pleshkova I.M.Imshinetskiy M.S.Gerasimenko E.A.belov V.V.Kumeiko D.n.Kozyrev K.A.Fomenko V.V.Mostovaya b.R.Torpanov A.R.biktimirov I.S.Osmushko S.L.Sinebryukhov S.V.Gnedenkov Institute of Chemistry FEb RAS 159 Pr.100-letiya VladivostokaVladivostok 690022Russia Far Eastern Federal University 10 Ajax BayRussky IslandVladivostok 690922Russia A.V.Zhirmunsky national Scientific Center of Marine biology FEb RAS 17 St.PalchevskogoVladivostok 690041Russia Regional Clinical Dermatovenerological Dispensary 18 V St.GamarnikaVladivostok 690033Russia nMIC“Treatment and Rehabilitation Center” 3 Ivankovskoe highwayMoscow 125367Russia

In this study,a calcium-phosphate coating was formed on a Mg-Mn-Ce alloy by the plasma electrolytic oxidation(PEO).The antibiotic vancomycin,widely used in the treatment of infections caused by Staphylococcus aureus(***),was impregnated into the *** with vancomycin showed high bactericidal activity against *** mechanical and electrochemical properties of the formed coatings were studied,as well as in vitro cytotoxicity tests and in vivo tests on mature male rats were *** to SEM,EDS,XRD and XPS data,coatings had a developed morphology and contained hydroxyapatite,which indicates high *** analysis of roughness of coatings without and with vancomycin did not reveal any differences,confirming the high roughness of the *** electrochemical tests,an increase in corrosion resistance by more than two times after the application of PEO coatings was *** to the results of an in vivo study,after 28 days of the implantation of samples with calcium phosphate PEO coating and vancomycin,no signs of inflammation were observed,while an inflammatory reaction developed in the area of implantation of bare alloy,followed by *** release tests from the coatings show a sharp decrease in the concentration of the released antibiotic on day 7 and then a gradual decrease until day *** the experiment,no significant deviations in the condition and behavior of the animals were observed;clinical tests did not reveal a systemic toxic reaction.

关键词： bioactive coatings biocompatibility Mg alloy Plasma electrolytic oxidation Hydroxyapatite Vancomycin

A review on perovskite solar cells (PSCs),materials and applications

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Journal of Materiomics 2021年第5期7卷 940-956页

作者： n.suresh Kumar K.Chandra babu naidu Department of Physics JNTUA College of EngineeringAnantapuramu515002A.PIndia Dept.of Physics GITAM Deemed to be UniversityBangalore562163KarnatakaIndia

In recent years,the perovskite solar cells have gained much attention because of their ever-increasing power conversion efficiency(PCE),simple solution fabrication process,flyable,light-weight wearable and deployable for ultra-lightweight space and low-cost materials constituents *** the last few years,the efficiency of perovskite solar cells has surpassed 25%due to high-quality perovskite-film accomplished through low-temperature synthesis techniques along with developing suitable interface and ***,the stability of perovskite solar cells has attracted much well-deserved *** this article we have focused on recent progress of the perovskite solar cells regarding their crystallinity,morphology and synthesis ***,demonstrated different layers such as electron transport-layers(ETLs),hole transport-layers(HTLs)and buffer-layers utilized in perovskite solar-cells,considering their band gap,carrier mobility,transmittance *** of various tin(Sn),carbon and polymer-based perovskite solar cells and their potential of commercialization feasibility has also been discussed.

关键词： Perovskite solar-cells Power conversion efficiency Hole transport layer Electron transport layer buffer layer Photovoltaic devices

Xanthan Sulfuric Acid： An Efficient bio-supported and Recy- clable Solid Acid Catalyst for the Synthesis of 2-Aryl Thiadiazolo benzimidazoles

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Chinese Journal of Chemistry 2012年第4期30卷 947-950页

作者： Kuarm,b.suresh Janardan,b. Crooks,Peter A. Rajitha,b. Department of Chemistry National Institute of TechnologyWarangalAPIndia Department of Pharmaceutical Sciences College of PharmacyUniversity of Arkansas for Medical SciencesLittle RockAR 72205U.S.A.

Xanthan sulfuric acid is an efficient solid acid catalyst for the preparation of 2-aryl benzimidazoles in excellent yields. This method is applicable for the reaction of benzo[c][ 1,2,5]thiadiazole-4,5-diamine with aldehydes by sim- ple physical grinding at room temperature. The salient features of the present methodology is cheaper process, easy synthesis of stable catalyst and the catalyst can be easily recycled without significant loss of activity.

关键词： benzimidazoles benzo[c]thiadiazole-4,5-diamine biodegradable recyclable xanthan sulfuric acid (XSA)

Effect of cinnamaldehyde on Rhizopus stolonifer and on the conservation of sweet potato

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Food Quality and Safety 2024年第1期8卷 212-225页

作者：陈晨薛智超 Penta Pristijono John b.Golding 陈刚李永新杨虎清 College of Food and Health Zhejiang A&F UniversityHangzhouChina Zhejiang Provincial Key Laboratory of Resources Protection and Innovation of Traditional Chinese Medicine Zhejiang A&F UniversityHangzhouChina School of Environmental and Life Sciences University of NewcastleOurimbahNSWAustralia nSW Department of Primary Industries OurimbahNSWAustralia

Objectives:Rhizopus stolonifer,which causes soft rot of sweet potato,has resulted in substantial loss of economy *** and Methods:The antifungal effect and mechanism of cinnamaldehyde(CIn)against *** were explored by biochemical analysis and RnA-sequencing in this research,and the edible quality of CIn-treated sweet potato was ***:The results showed that CIn inhibited the growth of *** and reduced the incidence of soft rot in sweet potato at a minimum inhibitory concentration of 1000μL/*** damage of the cell walls of *** by CIn was associated with the upregulation of *** leakage and malondialdehyde content increased following CIn-treatment,which was correlated with increased reactive oxygen species levels and decreased catalase *** of ERG genes and oxidative stress-related genes following CIn treatment was associated with impaired cell membrane *** mitochondrial structure of *** was damaged by CIn treatment resulting in decreased respiration rates and ATP production,which was correlated with lower expression levels of IDH1,COX4,and ***:Our research suggests that the inhibition of CIn on *** was related to the disruption of its normal gene expression network,and CIn maintained the nutritional and edible quality of sweet *** study provides valuable insights into the antifungal mechanism of CIn on *** and the maintenance of root quality,which contributes to the effcient use of CIn for controlling soft rot in sweet potato.

关键词： Ipomoea batatas soft rot cinnamaldehyde antifungal mechanism transcriptome

Plant community on a volcano mountaintop reveals unique high-altitude vegetation in southeastern brazil

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Journal of Mountain Science 2024年第9期21卷 3018-3030页

作者： Igor Musauer KESSOUS Ruy JoséValka ALVES nílber Gonçalves da SILVA Amilcar Walter SAPORETTI JUnIOR biodiversity Laboratory Federal Institute of EducationScience and Technology of Southern Minas Gerais(IFSULDEMINAS)Av.Dirce Pereira Rosa300-Jardim Esperança37713-100Poços de CaldasMGBrazil Department of botany National MuseumFederal University of Rio de JaneiroQuinta da Boa Vista s.n.São Cristóvão20949-040Rio de JaneiroRJBrazil Gothenburg Global biodiversity Centre Carl Skottsbergs Gata 22BSE 41319GothenburgSweden

Mountains exhibit a high degree of endemism and diversity,however,quantifying their biodiversity can be *** to islands,species isolation in mountainous regions results in comparable patterns of evolution and extinction,rendering their biodiversity unique and highly susceptible to anthropogenic *** topographic relief in mountains plays a crucial role in creating habitat complexity,which in turn contribute to high plant ***,we investigated plant diversity in the volcano mountaintop vegetation on the Poços de Caldas Plateau,a region situated in the ecotone between the Atlantic Forest and Cerrado,characterized by natural radiation and significant anthropogenic *** employed an automated approach through the filtering of georeferenced and non-georeferenced data to obtain a list of plant species in the ***,we statistically investigated the similarity among different high-altitude vegetations belonging to the campos de altitude from the Atlantic Forest and campos rupestres from the *** plateau exhibits high plant diversity,including 1,659 specific and infraspecific taxa,especially belonging to Asteraceae and *** analyses suggest that geographical distance is a strong predictor of dissimilarity and that the Poços de Caldas Plateau is more floristically related to the campos rupestres,despite being associated with campos de *** region possesses a unique set of biodiversity,indicating that it may be a distinct ***,we hypothesize that Pleistocene events likely influenced the conformation of the current floristic composition in the region through species interchange between the Cerrado and Atlantic *** study also highlights the few taxa assessed for conservation status and anthropogenic threats that this habitat is facing.

关键词： Atlantic Forest biogeography Cerrado Community ecology Grassland

Inflow and outflow permeability tests in a very soft clay under low stresses

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第8期16卷 3270-3283页

作者： J.W.S.Vargas F.A.b.Danziger F.R.Lopes T.Lunne Federal University of Rio de Janeiro Rio de JaneiroBrazil norwegian Geotechnical Institute OsloNorway

In situ inflow and outflow permeability tests with the bAT probe at SarapuíII soft clay test site are presented.A description of the bAT permeability test is provided,discussing its advantages and shortcomings,especially in the case of very soft clays under low *** pressures were monitored during probe installation and were found to be slightly lower than piezocone u2 pore pressures,consistent with the position of the *** role of filter tip saturation was investigated after the usual saturation procedure provided an unsatisfactory pore pressure response during probe *** show that the vacuum saturation procedure provides adequate response during installation and increases the reliability of the coefficient of permeability determination in early *** inflow and outflow tests yielded similar results,indicating that careful execution of the test can lead to good test repeatability regardless of the loading *** sequences of alternated inflow and outflow tests have yielded similar results,indicating that soil reconsolidation and filter clogging were negligible in the tests *** are presented concerning the relationship between index parameters and the in situ coefficient of permeability for SarapuíII clay,which plot outside the range of existing databases.

关键词： Permeability test Soft clay bAT probe Inflow and outflow tests

Integration between Genomic and Computational Statistical Surveys for the Screening of SnP Genetic Variants in Inflammatory bowel Disease (IbD) Pediatric Patients*

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Computational Molecular bioscience 2024年第3期14卷 146-191页

作者： Dago Dougba noel Koffi n’Guessan bénédicte Sonia Dagnogo Olefongo Daramcoum Wentoin Alimata Marie-Pierre Mauro Giacomelli Dagnogo Dramane Eboulé Ago Eliane Rebecca Yao Saraka Didier Martial Diarrassouba nafan Giovanni Malerba Raffaele badolato Department of Clinical and Experimental Sciences University of Brescia Brescia Italy Angelo nocivelli Institute of Molecular Medicine Childrens Hospital ASST Spedali Civili Brescia Italy Unit of biostatistics and biomathematics & Unit of bioinformatics Department of Molecular and Translational Medicine University of Brescia Brescia Italy biological Sciences Training and Research Unit Department of Genetic and Biochemistry Peleforo Gon Coulibaly University Korhogo Cte dIvoire Department of neurosciences Biomedicine and Movement Sciences Section of Biology and Genetics University of Verona Verona Italy biosciences Training and Research Unit Biology and Health Laboratory Felix Houphouet-Boigny University Abidjan Cte dIvoire

Inflammatory bowel diseases (IbD) are complex multifactorial disorders that include Crohn’s disease (CD) and ulcerative colitis (UC). Considering that IbD is a genetic and multifactorial disease, we screened for the distribution dynamism of IbD pathogenic genetic variants (single nucleotide polymorphisms;SnPs) and risk factors in four (4) IbD pediatric patients, by integrating both clinical exome sequencing and computational statistical approaches, aiming to categorize IbD patients in CD and UC phenotype. To this end, we first aligned genomic read sequences of these IbD patients to hg19 human genome by using bowtie 2 package. next, we performed genetic variant calling analysis in terms of single nucleotide polymorphism (SnP) for genes covered by at least 20 read genomic sequences. Finally, we checked for biological and genomic functions of genes exhibiting statistically significant genetic variant (SnPs) by introducing Fitcon genomic parameter. Findings showed Fitcon parameter as normalizing IbD patient’s population variability, as well as inducing a relative good clustering between IbD patients in terms of CD and UC phenotypes. Genomic analysis revealed a random distribution of risk factors and as well pathogenic SnPs genetic variants in the four IbD patient’s genome, claiming to be involved in: i) Metabolic disorders, ii) Autoimmune deficiencies;iii) Crohn’s disease pathways. Integration of genomic and computational statistical analysis supported a relative genetic variability regarding IbD patient population by processing IbD pathogenic SnP genetic variants as opposite to IbD risk factor variants. Interestingly, findings clearly allowed categorizing IbD patients in CD and UC phenotypes by applying Fitcon parameter in selecting IbD pathogenic genetic variants. Considering as a whole, the study suggested the efficiency of integrating clinical exome sequencing and computational statistical tools as a right approach in discriminating IbD phenotypes as well as improvi

关键词： Inflammatory bowel Disease (IbD) Crohn Disease (CD) Ulcerative Colitis (UC) Clinical Exome Analysis Computational Statistic SnP Genetic Variants

Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain

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Journal of Sport and Health Science 2024年第2期13卷 245-255页

作者： Cecilie Skarstad norevik Aleksi M.Huuha Ragnhild n.RФsbjФrgen Linda Hildegard bergersen Kamilla Jacobsen Rodrigo Miguel-dos-Santos Liv Ryan belma Skender Jose bianco n.Moreira Asgeir Kobro-Flatmoen Menno P.Witter nathan Scrimgeour Atefe R.Tari Cardiac Exercise Research Group(CERG) Department of Circulation and Medical ImagingNorwegian University of Science and Technology7491TrondheimNorway Department of neurology and Clinical neurophysiology St.Olavs University Hospital7030TrondheimNorway Institute of Oral biology University of Oslo0372OsloNorway Department of Physiology Federal University of SergipeS~ao Cristov~ao49100-000SergipeBrazil Centre of Molecular Inflammation Research Department of Clinical and Molecular MedicineNorwegian University of Science and Technology7491TrondheimNorway Kavli Institute for Systems neuroscience Centre for Neural Computationand Egil and Pauline Braathen and Fred Kavli Centre for Cortical MicrocircuitsNorwegian University of Science and Technology7030TrondheimNorway K.G.Jebsen Centre for Alzheimer’s Disease Norwegian University of Science and Technology7030TrondheimNorway

background:Exercise training promotes brain plasticity and is associated with protection against cognitive impairment and Alzheimer’s disease(AD).These beneficial effects may be partly mediated by blood-borne *** we used an in vitro model of AD to investigate effects of blood plasma from exercise-trained donors on neuronal viability,and an in vivo rat model of AD to test whether such plasma impacts cognitive function,amyloid pathology,and ***:Mouse hippocampal neuronal cells were exposed to AD-like stress using amyloid-βand treated with plasma collected from human male donors 3 h after a single bout of high-intensity *** in vivo studies,blood was collected from exercise-trained young male Wistar rats(high-intensity intervals 5 days/week for 6 weeks).Transgenic AD rats(McGill-R-Thyl-APP)were inj ected 5 times/fortnight for 6 weeks at2 months or 5 months of age with either(a)plasma from the exercise-trained rats,(b)plasma from sedentary rats,or(c)*** function,amyloid plaque pathology,and neurogenesis were *** plasma used for the treatment was analyzed for 23 ***:Plasma from exercised donors enhanced cell viability by 44.1%(p=0.032)and reduced atrophy by 50.0%(pn amyloid-β-treated *** vivo exercised plasma treatment did not alter cognitive function or amyloid plaque pathology but did increase hippocampal neurogenesis by~3 fold,regardless of pathological stage,when compared to saline-treated *** of 7 cytokines were significantly reduced in exercised plasma compared to sedentary ***:Our proof-of-concept study demonstrates that plasma from exercise-trained donors can protect neuronal cells in culture and promote adult hippocampal neurogenesis in the AD rat *** effect may be partly due to reduced pro-inflammatory signaling molecules in exercised plasma.

关键词： Cytokines High-intensity interval training Inflammation neurons Plasma transfusion

Assessment of Cross-coupling Effects in PV String-integrated-converters with P&O MPPT Algorithm Under Various Partial Shading Patterns

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CSEE Journal of Power and Energy Systems 2022年第4期8卷 1013-1028页

作者： Suneel Raju Pendem suresh Mikkili the Electrical and Electronics Engineering Department National Institute of Technology GoaPonda 403401India

A signifcant challenge in the progress and development of building-Integrated-Photovoltaic(b-I-PV)systems is concerned with the extraction of maximum power from PV *** PV system archtecture is an essential feature to extract the maximum *** conventional PV-centralinverter architecture consists of various connections among the PV modules,which are sensitive to shading effects and pro-duces mismatching power loss under partial shading conditions(PSCs),Hence,photovoltaic-distributed-maximum power point tracking(PV-D-MPPT)architecture has been proposed to extract the maximum ***-1 D-MPPT architecture,the output terminals of DC-DC converters are connected either in series or parallel *** main limitation of the series configuration in open-loop MPPT control is the crosscoupling *** of cross-coupling effects,the maximum-power-point(M-P-P)operation of shaded PV modules is lost under *** lost in M-P-P operation of shaded PV module also affects the unshaded modules M-P-P *** crosscoupling ffeets,the DC-DC converters are consuming the power instead of delivering to the *** the research activity,there are hardly any papers presenting a clear,comprehensive and mathematical analysis on the existence of cross-couplings in PV string-integrated-converters(S-1-Cs).This article presents a mathematical analysis and also explains the conditions for the existent of cross-coupling *** experimental results also validate with the mathematically analysed *** article also discusses the modeling of the two-diode model of PV module,design of boost type S-1C,and the Perturb and Observe(P&O)MPPT algorithm implementation.

关键词： Cross-coupling ffects mismatching power loss partial shading conditions(PSCs) PV-central-inverter architecture PV-D-MPPT architecture S-I-Cs series configuration