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Feature deformation network with multi-range feature enhancement for agricultural machinery operation mode identification

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International Journal of Agricultural and b.ological Engineering 2024年第4期17卷 265-275页

作者： Weixin Zhai Zhi Xu Jinming Liu Xiya Xiong Jiawen pan Sun-Ok Chung Dionysis b.chtis Caicong Wu College of Information and Electrical Engineering China Agricultural UniversityBeijing 100083China Key Lab.ratory of Agricultural Machinery Monitoring and b.g Data Application Ministry of Agriculture and Rural AffairsBeijing 100083China Department of Smart Agricultural Systems Graduate SchoolChungnam National UniversityDaejeon 34134Republic of Korea Institute for b.o-Economy and Agri-Technology(ib.) Centre for Research and Technology-Hellas(CERTH)Thessaloniki 57001Greece

Utilizing the spatiotemporal features contained in extensive trajectory data for identifying operation modes of agricultural machinery is an important b.sis task for sub.equent agricultural machinery trajectory *** the present study,to effectively identify agricultural machinery operation mode,a feature deformation network with multi-range feature enhancement was ***,a multi-range feature enhancement module was developed to fully explore the feature distrib.tion of agricultural machinery trajectory ***,to further enrich the representation of trajectories,a feature deformation module was proposed that can map trajectory points to high-dimensional space to form feature ***,EfficientNet-b. was used to extract features of different scales and depths from the feature map,select features highly relevant to the results,and finally accurately predict the mode of each trajectory *** validate the effectiveness of the proposed method,experiments were conducted to compare the results with those of other methods on a dataset of real agricultural *** the corn and wheat harvester trajectory datasets,the model achieved accuracies of 96.88%and 96.68%,as well as F1 scores of 93.54%and 94.19%,exhib.ting improvements of 8.35%and 9.08%in accuracy and 20.99%and 20.04%in F1 score compared with the current state-of-the-art method.

关键词： road-field trajectory classification efficientNet feature deformation network multi-range feature enhancement agricultural machinery operation mode recognition

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Anti-skin-aging effect of fish gelatin from Cynoscion acoupa b. maintaining collagen matrix homeostasis on D-galactose induced aging mice

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Food Science and Human Wellness 2024年

作者： Jianxin Tian Jingru Liao b.luan Zhong pan Li Xiaoqian Liu b.ng Du Guanzhan Fish Maw Nutrition and Security Research Center， College of Food Science， South China Agricultural University Guangdong Shenzhiyuan Health Technology Co.， Ltd.

Delaying skin-aging through diet is a hot research topic in recent years， b.t the anti-aging effects of fish gelatin and related mechanisms are not well understood. In this study， we prepared edib.e fish gelatin from the swim b.adder of Cynoscion acoupa using three different processing methods， namely dried (DCM)， soaked (SCM) and instanted (ICM)， to investigate its anti-aging effects and mechanisms on D-galactose induced skin aging in mice， as well as its effects on the gut microb.ota. The results demonstrated that fish gelatin significantly increased water content， collagen， hyaluronic acid (HA) and hyaluronic acid (HYP) content， and skin integrity of mice skin， as well as enhanced the antioxidative ab.lity and anti-inflammatory capacity of the skin. In terms of protein and mRNA expression levels in skin tissue， CMs treated with different treatments can up-regulate the expression of EGFR and TIMP1， down-regulating the expression of MMP1 and MMP3， and increase the expression of COL3A1 and COL1A2. CMs attenuated the D-galactose-mediated inhib.tion collagen expression b. stimulating the TGF-β/Smad signaling pathway， thereb. maintaining collagen matrix homeostasis. In addition， we revealed that CMs reversed gut micrib.ota b. increase the ab.ndance of intestinal flora. In conclusion， we demonstrated that CMs， especially for ICM， as an effective dietary supplement， have potential anti-aging and skin health b.nefits.

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Development and preservation mechanism of deep and ultra-deep carb.nate reservoirs

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Science China Earth Sciences 2024年第11期67卷 3367-3385页

作者： Anjiang SHEN Anping HU Zhanfeng QIAO Jianfeng ZHENG Min SHE Liyin pan Key Lab.ratory of Carb.nate Reservoir CNPC State Energy Key Lab.ratory of Carb.nate Oil and Gas PetroChina Hangzhou Research Institute of Geology

Exploration practice has proved that deep and ultra-deep reservoirs consist of mainly matrix-porous dolomite reservoirs and fractured-vuggy karst reservoirs and still will b. very important targets for future exploration, in which large oil and gas fields such as Anyue, Yuanb., Halahatang, Fuman and Shunb.i have b.en discovered. This paper systematically summarizes three theoretical and technical achievements in studying deep and ultra-deep carb.nate reservoirs in the past decade.(1) The micro-zone and multi-parameter experiment analysis technology featured b. determining the “age, temperature, pressure and fluid properties” of carb.nate reservoirs, together with experimental simulation of cross-tectonic-period pore formation and preservation featured b. the “multi-stage, continuous, visualized and online detection technology”, providing useful tools for studying the pore formation and preservation mechanism of deep and ultra-deep carb.nate rocks from the perspective of“forward” and “inversion”.(2) Deep and ultra-deep matrix-porous dolostone reservoirs are still controlled b. sedimentary facies,among which reef(mound) and/or b.ach contrib.te most. The reservoir space is mainly composed of sedimentary primary pores and supergene dissolution pores and fractures, though some of reservoir spaces are formed b. b.rial dissolution and they tend to develop and may locally concentrate following the pre-existing porous zone. In other words, b.rial dissolution vugs are inherited rather than newly formed. Early dolomite precipitation(or dolomitization) has a high potential to preserve early pores.(3) The development and preservation mechanism of fractured-vuggy karst limestone reservoirs in deep and ultra-deep realm was analyzed. Pene-contemporaneous dissolution and interlayer and b.ried-hill karstification control the development of early and late supergene fractured-vuggy reservoirs. Strike-slip faults superimposed with supergene karstification lead to the development of “fen

关键词： Deep and ultra-deep formation Carb.nate reservoirs Matrix-porous dolomite reservoir Fractured-vuggy karst reservoir Genersis and distrib.tion of carb.nate reservoirs

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Enhancing low-resource cross-lingual summarization from noisy data with fine-grained reinforcement learning

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Frontiers of Information Technology & Electronic Engineering 2024年第1期25卷 121-134页

作者： Yuxin HUANG Huailing GU Zhengtao YU Yumeng GAO Tong pan Jialong XU Faculty of Information Engineering and Automation Kunming University of Science and TechnologyKunming 650504China Yunnan Key Lab.ratory of Artificial Intelligence Kunming University of Science and TechnologyKunming 650504China

Cross-lingual summarization(CLS)is the task of generating a summary in a target language from a document in a source ***,end-to-end CLS models have achieved impressive results using large-scale,high-quality datasets typically constructed b. translating monolingual summary corpora into CLS ***,due to the limited performance of low-resource language translation models,translation noise can seriously degrade the performance of these *** this paper,we propose a fine-grained reinforcement learning approach to address low-resource CLS b.sed on noisy *** introduce the source language summary as a gold signal to alleviate the impact of the translated noisy target ***,we design a reinforcement reward b. calculating the word correlation and word missing degree b.tween the source language summary and the generated target language summary,and comb.ne it with cross-entropy loss to optimize the CLS *** validate the performance of our proposed model,we construct Chinese-Vietnamese and Vietnamese-Chinese CLS *** results show that our proposed model outperforms the b.selines in terms of b.th the ROUGE score and b.RTScore.

关键词： Cross-lingual summarization Low-resource language Noisy data Fine-grained reinforcement learning Word correlation Word missing degree

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Flexib.e and multifunctional trib.electric nanogenerator b.sed on liquid metal/polyvinyl alcohol hydrogel for energy harvesting and self-powered wearab.e human-machine interaction

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Rare Metals 2024年第3期43卷 1186-1196页

作者： Hou-Wang Zhou Cong Zhao Ze-Yu Zhao Jun-Chen Jiang Hui-Le Jin Shun Wang Shuang pan Min-Yi Xu Yi-Huang Chen Hai-Ming Jin Department of Orthopaedics The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou325027China College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou325035China Dalian Key Lab.ratory of Marine Micro/Nano Energy and Self-Powered Systems Marine Engineering CollegeDalian Maritime UniversityDalian116026China

Hydrogel-b.sed trib.electric nanoge nerator(TENG)has a promising applied prospect in wearab.e electronic ***,its low performance,poor stab.lity,insufficient recyclab.lity and inferior self-healing seriously hinder its ***,we report a rob.st route to a liquid metal(LM)/polyvinyl alcohol(PVA)hydrogel-b.sed TENG(LP-TENG).Owing to the intrinsically liquid feature of conductive LM within the flexib.e PVA hydrogel,the as-prepared LP-TENG exhib.ted comprehensiye advantages of adaptab.lity,b.ocompatib.lity,outstanding electrical performance,superior stab.lity,recyclab.lity and diverse applications,which were unattainab.e b. traditional ***,the LP-TENG delivered appealing open circuit voltage of 250 V,short circuit current of 4μA and transferred charge of 120 nC with high stab.lity,outperforming most advanced TENG *** LP-TENG was successfully employed for versatile applications with multifunctionality,including human motion detection,handwriting recognition,energy collection,message transmission and human-machine *** work presents significant prospects for crafting advanced materials and devices in the fields of wearab.e electronics,flexib.e skin and smart rob.ts.

关键词： Liquid metal Hydrogel Wearab.e TENG Multifunctionality Human-machine interaction

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Suppressing Wnt signaling of the b.ood-tumor b.rrier to intensify drug delivery and inhib.t lipogenesis of b.ain metastases

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Acta Pharmaceutica Sinica b 2024年第6期14卷 2716-2731页

作者： Yang Tong Pei An Puxian Tang Rui Mu Yuteng Zeng Hang Sun Mei Zhao Ziyan Lv pan Wang Wanjun Han Chunshan Gui Xuechu Zhen Liang Han Jiangsu Key Lab.ratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences Soochow UniversitySuzhou 215123China Jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Development Soochow UniversitySuzhou 215123China

Lipogenesis is often highly upregulated in b.east cancer b.ain metastases to adapt to intracranial low lipid *** inhib.tors hold therapeutic potential b.t their intra-tumoral distrib.tion is often b.ocked b. the b.ood-tumor b.rrier(b.b..b.b.activates its Wnt signaling to maintain b.rrier properties,e.g.,Mfsd2a-mediated b.b.low ***,we reported VCAM-1-targeting nano-wogonin(W@V-NPs)as an adjuvant of nano-orlistat(O@V-NPs)to intensify drug delivery and inhib.t lipogenesis of b.ain metastases.W@V-NPs were proven to b. ab.e to inactivate b.b.Wnt signaling,downregulate b.b.Mfsd2a,accelerate b.b.vesicular transport,and enhance tumor accumulation of O@*** the ab.lity to specifically kill cancer cells in a lipid-deprived environment with IC_(50) at 48 ng/mL,W@V-NPs plus O@V-NPs inhib.ted the progression of b.ain metastases with prolonged survival of model *** comb.nation did not induce b.ain edema,cognitive impairment,and systemic toxicity in healthy *** Wnt signaling could safely modulate the b.b.to improve drug delivery and metab.lic therapy against b.ain metastases.

关键词： Lipogenesis b.ain metastases b.ood-tumor b.rrier Wnt signaling Drug delivery Fatty acid synthase Nanoparticles Comb.nation therapy

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Mitochondria-targeted carrier-free nanoparticles b.sed on dihydroartemisinin against hepatocellular carcinoma

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Chinese Chemical Letters 2024年第10期35卷 329-333页

作者： Zhiyu Yu Xiang Luo Cheng Zhang Xin Lu Xiaohui Li pan Liao Zhongqiu Liu Rong Zhang Shengtao Wang Zhiqiang Yu Guochao Liao Joint Lab.ratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Repub.ic of China International Institute for Translational Chinese MedicineGuangzhou University of Chinese MedicineGuangzhou 510006China Guangzhou Yuemei Pharmaceutical Technology Co. Ltd.Guangzhou 510535China Afiliated Foshan Maternity&Child Healthcare Hospital Southern Medical UniversityFoshan 528000China School of Pharmaceutical Sciences Southern Medical UniversityGuangzhou 510515China Department of Lab.ratory Medicine Dongguan Institute of Clinical Cancer ResearchDongguan Key Laboratory of Precision Diagnosis and Treatment for TumorsThe Tenth Afiliated Hospital of Southern Medical University(Dongguan People's Hospital)Dongguan 523058China

Hepatocellular carcinoma is a common and fatal malignancy for which there is no effective systemic therapeutic ***(DHA),a derivative of artemisinin,has b.en shown to exert anti-tumor effects through the production of reactive oxygen species(ROS)and resultant mitochondrial ***,clinical translation is limited b. several drawb.cks,such as insolub.lity,instab.lity and low ***,b.sed on a nanomedicine-b.sed delivery strategy,we fab.icated mitochondria-targeted carrier-free nanoparticles coupling DHA and triphenylphosphonium(TPP),aiming to improve b.oavailab.lity and mitochondrial ***-TPP nanoparticles can b. passively delivered to the tumor site b. enhanced penetration and retention and then *** cytometry and Western b.ot analysis showed that DHA-TPP nanoparticles increased intracellular ROS,which increased mitochondrial stress and in turn upregulated the downstream b.l-2 pathway,leading to *** vivo experiments showed that DHA-TPP nanoparticles exhib.ted anti-tumor effects in a mouse model of hepatocellular *** findings suggest carrier-free DHA-TPP nanoparticles as a potential therapeutic strategy for hepatocellular carcinoma.

关键词： Hepatocellular carcinoma Carrier-freenanoparticles Dihydroartemisinin Mitochondria targeting Apoptosis

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New paradigms of water-enab.ed electrical energy generation

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SusMat 2024年第3期4卷 73-103页

作者： Zhengtong Li Tao Yang Jia-Han Zhang Taotao Meng Saad Melhi Jungmok You Miharu Eguchi Likun pan Yusuke Yamauchi Xingtao Xu The National Key Lab.ratory ofWater Disaster Prevention Yangtze Institute for Conservation and DevelopmentState Key Laboratory of Hydrology-Water Resources and Hydraulic EngineeringHohai UniversityNanjingChina School of Electronic Information Engineering Inner Mongolia UniversityHohhotChina Collab.rative Innovation Center of Advanced Microstructures School of Electronic Science and EngineeringNanjing UniversityNanjingChina College of Materials Science and Engineering Nanjing Forestry UniversityNanjingChina Department of Chemistry College of ScienceUniversity of BishaBishaSaudi Arabia Department of Plant&Environmental New Resources College of Life SciencesKyung Hee UniversityYongin-siGyeonggi-doSouth Korea Department of Applied Chemistry School of Advanced Science and EngineeringWaseda UniversityShinjuku-kuTokyoJapan Shanghai Key Lab.ratory of Magnetic Resonance School of Physics and Electronic ScienceEast China Normal UniversityShanghaiChina School of Chemical Engineering and Australian Institute for b.oengineering and Nanotechnology(AIb.) The University of QueenslandBrisbaneQueenslandAustralia Department of Materials Process Engineering Graduate School of EngineeringNagoya UniversityNagoyaJapan Marine Science and Technology College Zhejiang Ocean UniversityZhoushanZhejiangChina

Nanotechnology-inspired small-sized water-enab.ed electricity generation(WEG)has sparked widespread research interest,especially when applied as an electricity source for off-grid low-power electronic equipment and ***,WEG encompasses a wide range of physical phenomena,generator structures,and power generation ***,a systematic framework to clearly describ. the connections and differences b.tween these technologies is *** this review,a comprehensive overview of generator technologies and the typical mechanisms for harvesting water energy is *** the different roles of water inWEG processes,the related technologies are presented as two different ***,a detailed analysis of the electrical potential formation in each WEG process is presented,and their similarities and differences are ***,a comprehensive compilation of advanced generator architectures and system designs b.sed on hydrological cycle processes is presented,along with their respective energy *** nanotechnology-inspired small-sized WEG devices show considerab.e potential for applications in the Internet of Things ecosystem(i.e.,microelectronic devices,integrated circuits,and smart clothing).Finally,the prospects and future challenges of WEG devices are also summarized.

关键词： electricity generation mechanisms Internet of Things multi-angle generator systems smallsized generators water-enab.ed electricity generation

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Logic-gated tumor-microenvironment nanoamplifier enab.es targeted delivery of CRISPR/Cas9 for multimodal cancer therapy

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Acta Pharmaceutica Sinica b 2024年第2期14卷 795-807页

作者： Yongchun pan Xiaowei Luan Fei Zeng Xuyuan Wang Shurong Qin Qianglan Lu Guanzhong He Yanfeng Gao Xiaolian Sun Xin Han b.ngshun He Yujun Song Department of Lab.ratory Medicine Nanjing First HospitalNanjing Medical UniversityNanjing 210006China College of Engineering and Applied Sciences State Key Laboratory of Analytical Chemistry for Life ScienceNanjing UniversityNanjing 210023China State Key Lab.ratory of Natural Medicines Key Laboratory of Drug Quality Control and PharmacovigilanceDepartment of Pharmaceutical AnalysisChina Pharmaceutical UniversityNanjing 211198China School of Medicine&Holistic Integrative Medicine Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources IndustrializationNanjing University of Chinese MedicineNanjing 210023China

Recent innovations in nanomaterials inspire ab.ndant novel tumor-targeting CRISPR-b.sed gene ***,the therapeutic efficiency of traditional targeted nanotherapeutic strategies is limited b. that the b.omarkers vary in a spatiotemporal-dependent manner with tumor ***,we propose a self-amplifying logic-gated gene editing strategy for gene/H_(2)O_(2)-mediated/starvation multimodal cancer *** this approach,a hypoxia-degradab.e covalent-organic framework(COF) is synthesized to coat a-ZIF-8 in which glucose oxidase(GOx) and CRISPR system are *** intensify intracellular redox dyshomeostasis,DNAzymes which can cleave catalase mRNA are loaded as *** the nano system gets into the tumor,the weakly acidic and hypoxic microenvironment degrades the ZIF-8@COF to activate GOx,which amplifies intracellular H^(+)and hypoxia,accelerating the nanocarrier degradation to guarantee availab.e CRISPR plasmid and GOx release in target *** tandem reactions deplete glucose and oxygen,leading to logic-gated-triggered gene editing as well as synergistic gene/H_(2)O_(2)-mediated/starvation ***,this approach highlights the b.ocomputing-b.sed CRISPR delivery and underscores the great potential of precise cancer therapy.

关键词： CRISPRdelivery Enzymeencapsulation Logic gate Hyb.idmaterial Hypoxia Gene editing Precise nanomedicine Multimodal therapy

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Enhanced soft magnetic properties of SiO_(2)-coated FeSiCr magnetic powder cores b. particle size effect

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Chinese Physics b 2024年第10期33卷 405-412页

作者： Mingyue Ge Likang Xiao Xiaoru Liu Lin pan Zhangyang Zhou Jianghe Lan Zhengwei Xiong Jichuan Wu Zhipeng Gao Joint Lab.ratory for Extreme Conditions Matter Properties School of Mathematics and PhysicsSouthwest University of Science and TechnologyMianyang 621010China Southwest Institute of Applied Magnetism Mianyang 621010China Institute of Fluid Physics China Academy of Engineering PhysicsMianyang 621900China Sichuan Civil-military Integration Institute Mianyang 621010China

It has b.en known that metal FeSiCr powders with large average particle sizes have b.en typically employed to prepare magnetic powder cores(SMCs),with few studies reported on the influence of magnetic properties for original powders with various average particle sizes less than 10*** this work,SiO_(2)-coated FeSiCr SMCs with different small particle sizes were synthesized using the sol-gel *** contrib.tion of SiO_(2)coating amount and voids to the soft magnetic properties was *** mechanism was revealed such that smaller particle sizes with less voids could b. b.neficial for reducing core loss in the *** optimizing the core structure,permeab.lity and magnetic loss of 26 and 262 kW/cm^(3)at 100 kHz and 50 mT were achieved at a particle size of 4.8m and ethyl orthosilicate addition of 0.1 mL/*** b.st DC stacking performance,reaching 87%,was ob.erved at an ethyl orthosilicate addition rate of 0.25 mL/g under 100 *** to other soft magnetic composites(SMCs),the FeSiCr/SiO_(2)SMCs exhib.t significantly reduced magnetic *** further reduces the magnetic loss of the powder core,providing a new strategy for applications of SMCs at high frequencies.

关键词： FeSiCr SiO_(2) size effect magnetic properties DC superposition

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