The objective of this project was to search for consensus in differential gene expression data and in regulation of differentially expressed genes among DNA microarray studies of atherosclerotic vessels and plaque. se...
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The objective of this project was to search for consensus in differential gene expression data and in regulation of differentially expressed genes among DNA microarray studies of atherosclerotic vessels and plaque. seventeen DNA microarray studies of atherosclerosis were analyzed. Only 19 genes were found to be differentially expressed in 3 or more of the studies. The nineteen genes belong to classic gene ontologies known to be involved in atherosclerosis: immunity and defense, metabolism, proteases, receptors, and signal transduction. four bioinformatics programs (TRED, rVIsTA, JAsPAR, and ariadne Pathways) were used to further analyze the promoter regions and common upstream regulators of the 19 genes. Twelve of the genes shared nine common upstream regulators, many of them known to affect atherosclerosis, and one possible new pathway was identified that may be involved in this disease.
Thisshort essay focuses on just one of the mythological paintings of Evelyn Pickering de Morgan,ariadne at Naxos of 1877 at The de Morgan foundation(figure 1).1 It consists of an iconographical and iconological analy...
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This short essay focuses on just one of the mythological paintings of Evelyn Pickering de Morgan,ariadne at Naxos of 1877 at The de Morgan foundation(figure 1).1 It consists of an iconographical and iconological analysis of the ancient legend of ariadne and Theseus,demonstrating Evelyn’s classical erudition and artistic mastery in visualizing a moment in the narrative,the desertion of ariadne by Theseus on the beach at Naxos.
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