检索结果-南通市图书馆

Advances in Infectious Diseases 2020年第2期10卷 140-147页

作者： Rosa Maria Dias Larissa rodrigues da costa Agostilina Renata dos Santos da Cruz Ramos Andrea Graças Ferreira Frazã o Clá udia Daniele Tavares Dutra Fernanda Maria Lima Moura Isameriliam Rosaulem Pereira da Silva José Luiz Fernandes Vieira Faculty of Nutrition Institute of Health Sciences Para Federal University Belem Brazil Pharmacy Faculty Campus Universitario do Guama Para Federal University Belem Brazil

Objective: To investigate the factors associated with malaria vivax infection in children and adolescents from an endemic area in the Eastern portion of the Brazilian Amazon basin. Methods: A case-control study was carried out in the municipality of Anajas, Brazil, from January 2016 to September 2017. Questionnaires were applied to the relative or the legal tutors of children and adolescents with questions regarding social and economic status, educational degree, knowledge about malaria, and the use of protective measures against mosquito bites. Anthropometric measures were performed in children and adolescents. Results: A total of 58 cases and 61 controls were included in the study. Most of the participants were male, eutrophics, and their relatives presented low educational degrees as well as low social and economic status. The knowledge of malaria was limited, but the percentage of individuals using long-lasting insecticidal nets was high. The presence of peri-domiciliary breeding sites for Anopheles vector was the most critical factor for malaria. Conclusion: The occurrence of malaria was associated with low social and economic status, a low educational degree, the unfamiliarity with malaria and the presence of breeding sites for Anopheles mosquito surrounding individual domiciles.

关键词： Infectious Diseases Malaria Epidemiology Risk Factor

Comparison of Three Experimental Models for Rat Osteoarthritis Induction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2016年第12期4卷 62-69页

作者： Henrique Ribeiro rodrigues-Neto Edilson Ferreira Andrade-Junior Denilson Jose Silva Feitosa-Junior André Lopes Valente Thiago Cesar Xavier Bianca Caroline do Nascimento Alho Renan Kleber costa Teixeira Fabio Vidal Moriya Rui Sérgio Monteiro de Barros Department of Orthopaedics and Traumatology Porto Dias Hospital Bel&eacute m Brazil Experimental Surgery Laboratory Par&aacute State University Bel&eacute m Brazil

Background: Osteoarthritis is a slowly progressive and debilitating disease with high prevalence in adult population. Knee is one of the joints most affected by this disorder. There are several models for animals’ osteoarthritis induction, however it is not identified any paper that compares these techniques. The present study was aimed to define the most appropriate model for rats osteoarthritis induction. Material and Methods: 40 Wistar rats were distributed into 4 groups of 10 animals each: normality group (NG);meniscectomy group (MG);quinolone group (QG) and iodoacetate group (IG). Radiographic images of the rat’s knees were analyzed as well as the amount of chondrocytes in the epiphyseal and articular cartilage. Results: In the radiographic analysis, there was a low correlation between the raters. Regarding the amount of chondrocytes in the epiphyseal cartilage, it was noticed that the IG and QG groups had fewer chondrocytes than NG, in contrast to MG that reported similar results to normality (p > 0.05). There was no significant difference between IG and QG groups (p > 0.05). Regarding the amount of chondrocytes in articular cartilage, it was noticed that the IG group showed fewer chondrocytes than NG (p 0.05). There was no significant difference between QG and MG groups (p > 0.05). Conclusion: Intraarticular injection of iodoacetate in rats is the model with greatest effect on reduction of chondrocytes amount.

关键词： Osteoarthritis Knee Joint Experimental Arthritis Animal Disease Models Rats

Oily Water Treatment by Ceramic Membrane: Modeling and Simulation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Fluid Dynamics 2021年第1期11卷 1-19页

作者： Adriana Barbosa da costa Pereira Hortência Luma Fernandes Magalhães Leonardo Pereira de Lucena Silva Cristiane Arcoverde Passos Ricardo Soares Gomez Balbina Raquel de Brito Correia Severino rodrigues de Farias Neto Antonio Gilson Barbosa de Lima Department of Chemical Engineering Federal University of Campina Grande Campina Grande Brazil Department of Industry Federal Institute of Paraiba Cajazeiras Brazil Department of Chemical Engineering Federal University of Paraná Curitiba Brazil Department of Mechanical Engineering Federal University of Campina Grande Campina Grande Brazil

The separation process of oily water using membranes has attracted the attention of researchers and engineers. The greater problem in the use of membrane separation process is the reduction in permeate flux due to clogged pores by oil deposition inside the membrane or by the effect of the concentration polarization. For this purpose, a theoretical study of a water/oil separation module was performed. This device consists of a tubular ceramic membrane provided with a rectangular inlet section. Numerical simulations were performed using Ansys CFX software to solve the mass and momentum conservation equations in the fluid and porous domains. Here was adopted the RNG k-ε turbulence model. The effect of the membrane porosity and the inlet velocity of the fluid mixture on the two-phase flow behavior inside the separation module were evaluated. Results of the volumetric fraction, velocity and pressure fields of the oil and water phases are presented and analyzed. The results indicate a higher oil concentration within the membrane for the cases of higher porosity, and that the inlet fluid mixture velocity does not substantially affect the velocity profile within the separation module. It is found that the maximum separation efficiency of the module was obtained with feed velocity of 40 m/s and membrane porosity of 0.44.

关键词： Ceramic Membranes Separation Process Computational Fluid Dynamics CFX

Novel Immunogenic Epitopes in the NaPi-IIb Protein: Production of Monospecific Antibodies Using Synthetic Peptides Outlined on Isoform Specific Regions of the Type IIb Sodium-Dependent Phosphate Transporter (NaPi-IIb)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2016年第2期7卷 129-151页

作者： Ângela alice Amadeu Megale Jorge Mário da costa Ferreira Júnior Letícia Batista Azevedo Rangel Maria Del Pilar Estevez Diz Max Senna Mano Paulo Marcelo Gehm Hoff Priscila Hess Lopes Roberto Jun Arai Wilmar Dias da Silva Laboratório de Imunoquímica Instituto Butantan S&atildeo Paulo Brazil Departamento de Ciências Farmacêuticas Universidade Federal do Espírito Santo Espírito Santo Brazil Departamento de Pesquisa Clínica Instituto do C&acircncer do Estado de S&atildeo Paulo S&atildeo Paulo Brazil

NaPi-IIb is a multiple passage protein membrane which is primarily responsible for phosphate uptake in the kidney and in the small intestine. Beyond its physiological functions, their involvement with carcinogenesis was initially described in mid-2003, due to its distinct level of expression in normal and tumor cells of the ovary. Although less common than cervical cancer, epithelial ovarian cancer is considered the most lethal gynecologic malignancy, which is mainly due to diagnosis in the advanced stages as a result of the absence of symptoms during the onset of the disease and the lack of tools for early detection. Here, we produce antibodies that are anti-synthetic peptides that are derived from the regions of second extracellular loop of NaPi-IIb, which is a non-overlapping portion of MX35 epitope. These two 15 distinct amino acid residue peptides, designated as Let#1 and Let#2, are engineered in a very thorough way to detect specific sites only in this isoform, thus excluding cross-reactivity with other carriers of the same family. The lack of immunogenicity of small peptides is surpassed by the conjugation with carrier proteins. Using immunochemical methods, we demonstrate that polyclonal antibodies that are mono-specific for the Let#1 and Let#2 peptides recognize proteins that express similar amino acid sequences during blood circulation. Additionally, using flow cytometry, we identify NaPi-IIb in NIH:OVCAR-3 cells. The clear identification of two shorter peptides on the extracellular loop of NaPi-IIb, which are far from the monoclonal antibody MX35-recognizing epitopes, adds new promising tools for ovarian cancer follow-up and staging.

关键词： NaPi2b Peptides Antibodies Ovarian Cancer

Effects of Gaseous Drinks in Wistar Rats Esophagus

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2017年第5期5卷 32-43页

作者： Thiago Dornelas de Oliveira Marcelli Elioterio Gaspar Larissa Menezes Viana Braga Joice Meire rodrigues Rebeca Nogueira Falcao Santos Suelen Gaudino Moura Nayara Barbosa Bicalho Lamara Laguardia Valente Rocha Daniel Almeida da costa Marcus Vinicius de Mello Pinto Academic of the Graduate Course in Medicine of the University Center of Caratinga CaratingaBrazil Religious Sciences from the Pontifical Catholic University of Sao Paulo-PUC/SP Sao PauloBrazil University Center of Caratinga CaratingaBrazil The Institute of Health Sciences at UNEC CaratingaBrazil The Medical School at the Center of Higher Education of Valenca ValencaBrazil The Cellurare Institute Center of Laser Treatment and Cell Therapy PetropolisBrazil

The consumption of beverages and processed foods, mainly soft drinks, has been incorporated into the usual diet of children, adolescents and adults frequently in recent years. The present study aimed to study the effects of carbonated drinks on Wistar rats, based on the macroscopic and histological morphology of the esophagus. Fifteen Wistar rats were divided into three groups: control group;group fed with ration and cola-type refrigerant ad libitum and group fed with ration and gas industrialized water ad libitum, for a trial period of 90 days. For histopathology and morphology, the esophagus was removed, prepared in slides and stained with hematoxylineosin. Images of the sections were captured for analysis and classification of the inflammatory infiltrate. For morphometry, ten grid fields of 100 points were evaluated in the 40x eyepiece, totaling 3000 points per animal. The results demonstrate that the refrigerant treatment induced the following structural changes in the rats: significant reduction of weight in relation to the control group;inflammatory infiltrate predominantly diffuse mild to moderate and tissue edema. The rats treated with carbonated water had similar results to the control, besides signs of healing and tissue repair.

关键词： Soft Drinks Consumption Inflammation Carbonate Beverages

Sensitivity of a Rapid Mix Test with Combined Synthetic Antigens Derived from Mycobacterium Leprae PGL-1 for Diagnosis and Surveillance of Leprosy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Immunology 2020年第1期10卷 1-9页

作者： Maria do Perpétuo Socorro Amador Silvestre Maxwell Furtado de Lima Antonio G.P.Pereira Aline rodrigues Bernardo Rafaela Lopes Diniz Pedro Paulo Ferreira Ribeiro Edimílson Domingos da Silva Luana Nepomuceno Gondim costa Lima Instituto Evandro Chagas Rodovia BR-316km 07AnanindeuaParáBrasil Programa de Desenvolvimento Tecnologico de reativos para diagnostico GPRED-Bio Manguinhos-FioCruzRio de JaneiroBrasil

Introduction: In the Americas, Brazil contributes 91.63% of the total cases and the state of Pará still has high endemia for leprosy. Objective: To analyze the performance of a rapid test for the diagnosis and epidemiological surveillance of leprosy in endemic areas. Methods: The sample consisted of 70 MB multibacillary leprosy (MB) patients, 63 paucibacillary (PB) patients, and 80 intradomiciliary consanguineous contacts (ICSCO) of patients. A rapid test with a 15-minute reading was applied using two prototypes: prototype 1, double test with trisaccharide antigen (NT-P-BSA) at 1a. line (83.2 ng/test) and disaccharide antigen (ND-O-BSA) at 2a. (83.2 ng/test), both with a flow of 0.08 μL/mm with a 10 μC membrane, anti-IgM conjugate with a flow of 0.040 μL/mm and a Tris-Triton and prototype 2 runner buffer with MIX antigen (trisaccharide + disaccharide) in the same concentrations and conditions of prototype 1. Results: The comparison of the MIX test positivity rate and the disaccharide or trisaccharide doublet test across all samples was statistically significant, demonstrating that the MIX test had higher seropositivity rates compared to the ND-O-BSA or NT-P-BSA. It was demonstrated that the MIX test showed a good performance, with 25.39% of the PB patients negative for the disaccharide and trisaccharide duplet test, but positive for MIX. Conclusions: These data suggest the potential for further optimizing the performance by adding other synthetic antigens to the MIX antigens.

关键词： Leprosy Diagnosis Rapid Test

Experimental and Analytical Study of Torsional Vibration under Multiaxial Loading in Time Domain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mechanics Engineering and Automation 2016年第3期6卷 148-157页

作者： Dionisio Jose rodrigues da costa Ladario da Silv Jorge rodrigues Duran Jose Flavio Feiteira Programa de Pos-graduacao em Engenharia Metalurgica (PPGEM) Escola Industrial Metalurgica de Volta Redonda (EEIMVR)Universidade Federal Fluminense (UFF) Volta Redonda 27255-125 R J Brasil Posto Regional de Policia Tecnico-Cientifica de Volta Redonda (PRPTC-VR) Volta Redonda 27180-000 R J Brasil Departamento de Fisica lnstituto de Ciencias Exatas (1CEx) UFF Volta Redonda 27213-145 RJ Brasil Departamento de Engenharia Mecdnica EEIMVR UFF Volta Redonda 27255-125 R J Brasil

Food and Nutritional Security in the Refugee Women’s Life Narratives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2023年第11期14卷 1031-1042页

作者： Juliana Vidal Vieira Guerra Valdecyr Herdy Alves Brenda Caroline Martins da Silva Tatiana do Socorro dos Santos Calandrini Giovanna Rosario Soanno Marchiori Ediane de Andrade Ferreira Maria Bertilla Lutterbach Riker Branco Diego Pereira rodrigues Departamento de Nutriç &#227o Aplicada Instituto de Nutri&#231&#227o Universidade do Estado do Rio de Janeiro Rio de Janeiro Brasil Programa Acadêmico em Ciências do Cuidado em Saúde Escola de Enfermagem Aurora de Afonso Costa Universidade Federal Fluminense Niterói Brasil Instituto de Ciências da Saúde Universidade Federal do Pará Belém Brasil Centro de Ciências da Saúde Universidade Federal de Roraima Boa Vista Brasil

Objective: To understand, based on the life narratives of refugee women, food and nutritional security. Method: Qualitative, descriptive, exploratory study, Narratives of life method, by Daniel Bertaux. Conducted with 11 participants, refugee women residing in the state of Rio de Janeiro, Brazil. Results: The meanings and feelings evidenced in the life narratives of refugee women expressed the insecurities and weaknesses with food in the resettlement. Final Considerations: Given the meanings and feelings regarding food in the refuge, it is expected that the present study will contribute to the elaboration of new action plans and intersectoral public policies of agile action to meet the demands of the refugee population, in the attempt to mitigate starvation, poverty, social differences and the compromised health status of the refugee population.

关键词： Food Security Feeding Behavior Refugees Human Migration Human Right to Adequate Food

Mean and Interannual Variability of Maize and Soybean in Brazil under Global Warming Conditions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Climate Change 2013年第4期2卷 237-253页

作者： Flávio Justino Evandro Chaves Oliveira Rafael de Avila rodrigues Paulo Henrique Lopes Goncalves Paulo Jorge Oliveira Ponte Souza Frode Stordal José Marengo Thieres G.da Silva Rafael Coll Delgado Douglas da Silva Lindemann Luiz Claudio costa Departamento de Engenharia Agrícola Universidade Federal de ViçosaVicosaBrazil Universidade Federal Rural da Amazônia Instituto Sócio-Ambiental e dos Recursos HídricosBelémBrazil Department of Geosciences University of OsloOsloNorway Instituto Nacional de Pesquisas Espaciais Cachoeira PaulistaBrazil Universidade Federal Rural de Pernambuco Unidade Academica de Serra TalhadaSerra TalhadaBrazil Universidade Federal Rural do Rio de Janeiro Instituto de Florestas/Departamento de Ciencias AmbientaisSeropédicaBrazil

Brazil is responsible for 27% of the world production of soybeans and 7% of maize. Mato Grosso and Para states in Brazil are among the largest producer. The viability to the cultivation of maize (Zea mays) and soybeans (Glycine max), for future climate scenarios (2070-2100, GHG) is evaluated based on crop modeling (DSSAT) forced by observational data and regional climate simulations (HadRM3). The results demonstrated that a substantial reduction in the yield in particular for maize may be expected for the end of the 21st century. Distinct results are found for soybeans. By applying the A2 climate changes scenario, soybean yield rises by up top 60% assuming optimum soil treatment and no water stress. However, by analyzing the inter-annual variability of crop yields for both maize and soybean, could be demonstrated larger year-to-year fluctuations under greenhouse warming conditions as compared to current conditions, leading to very low productivity by the end of the 21st century. Therefore, these Brazilian states do not appear to be economically suitable for a future cultivation of maize and soybeans. Improved adaptation measures and soil management may however partially alleviate the negative climate change effect.

关键词： Climate Changes Soybeans Maize

Prevalence of the Nursing Diagnosis Lack of Adherence in People Living with AIDS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Nursing 2016年第5期6卷 386-395页

作者： Richardson Augusto Rosendo da Silva Emilaine Rebouças Fernandes Vinicius Lino de Souza Neto Iellen Dantas Campos Verdes rodrigues Itaisa Fernandes Cardoso de Andrade Bﾨﾢrbara Coeli Oliveira da Silva Francisca Marta de Lima costa Cintia Capistrano Teixeira Rocha Olga Priscilla Gonçalves Department of Nursing Health Science Center Federal University of Rio Grande do Norte (UFRN) Central Campus Natal Brazil Federal University of Rio Grande do Norte/UFRN Natal Brazil Graduate Program in Nursing Federal University of Rio Grande do Norte/UFRN Natal Brazil Federal University of Piauí (UFPI) Teresina Brazil Doctor’s Health Strategy Japi Family/RN Natal Brazil

Introduction: In the 1990s, the development of highly active combination antiretroviral therapy in the treatment of AIDS was highlighted. The great benefit generated by the use of this treatment was the prolongation of survival of the people who got this disease, since it is no longer considered fatal, becoming a chronic condition. Objective: To identify the prevalence of the nursing diagnosis Lack of Adherence, its defining characteristics and related factors in people living with AIDS, to investigate the association between them and the prevalence rates. Methods: Cross-sectional study with 113 patients in a hospital in northeastern Brazil. For data analysis, the test of Pearson chi-square and Fisher’s exact test were used, and also calculated the prevalence rates. Results: Lack of Adherence diagnosis was present in 69% of the sample investigated. The defining characteristics and related factors that are statistically associated with that diagnosis were: lack of adherence behavior, missing scheduled appointments, complications related to development, insufficient skills to implement the system and complex treatment system. The first two characteristics had the highest chances for the development of this diagnosis. Conclusion: The study showed that the diagnostic studied was prevalent in these patients and 3 characteristics and 2 factors showed significant association.

关键词： Nursing Diagnosis Nursing Process Nursing Care HIV Acquired Immunodeficiency Syndrome