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Species from Darwin onward

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Integrative Zoology 2010年第3期5卷 187-197页

作者： anouk barberousse Sarah SAMADI Institute of History and Phylosophy of Sciences and Technics UMR 8590 National Center for Scientific ResearchUniversity Paris IENS Systematic Adaptation and EvolutionUMR 7138 CNRS-IRD-UMPC-MNHNFrance

Controversy regarding the species problem has been going on for many decades and no consensus has ever been reached about what a“species”really is and how best to define the *** Queiroz(1998)introduced a distinction between two aspects of this problem:on the one hand,the definition proper,and on the other,the criteria allowing biologists to recognize species in *** distinction is a first step on the way toward a solution of the *** the present paper,we show that de Queiroz’s distinction is made possible by the radical theoretical change introduced by *** emphasize that the species problem did not appear in the 20th century,but long before,and that Darwin addresses it indirectly in the Origin of *** might seem paradoxical to refer to Darwin’s views about species,because they are usually considered as ***,we propose that an analysis of these views in the context of Darwin’s own theory of evolution might reveal how a definition of the concept of species is made possible by being anchored to the very theory of *** this aim,we present a plausible reconstruction of Darwin’s implicit conception of species and show how this conception fits with the debates on species that took place in the 18th and 19th *** then turn to today’s biology and show what changes Darwin’s implicit conception of species has brought about relative to the species concept and species delimitation.

关键词： Buffon Darwin nomenclature species concepts taxonomy

Treatment responses in Asians and Caucasians with chronic hepatitis C infection

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World Journal of Gastroenterology 2008年第21期14卷 3416-3420页

作者： Kenneth K Yan Marianne Guirgis Amany Zekry Thuy Dinh anouk Dev Jacob George Alice Lee Department of Hepatology St George HospitalKogarahSydney 2217NSWAustralia Department of Gastroenterology Monash Medical CentreMelbourne 3168VictoriaAustralia Storr Liver Unit Westmead Millennium InstituteUniversity of Sydney and Westmead HospitalSydney 2217NSWAustralia Department of Gastroenterology and Hepatology Concord Repatriation HospitalConcordSydney 2217NSWAustralia

AIM：To conduct a multicentre retrospective review of virological response rates in Asians infected with genotype 1 chronic hepatitis C（CHC） treated with combination interferon and ribavirin and then to compare their responses to that among Caucasians.METHODS：Asian patients infected with genotype 1 CHC treated at 4 Australian centres between 2001 to 2005 were identified through hospital *** demographic characteristics,biochemical,virological and histological data and details of treatment were *** virological responses（SVR） in this cohort were then compared to that in Caucasian subjects,matched by genotype,age,gender and the stage of hepatic fibrosis.RESULTS：A total of 108 Asians with genotype 1 CHC were *** end of treatment response（ETR） for the cohort was 79% while the SVR was 67%.Due to the relatively advanced age of the Asian cohort,only sixty-four subjects could be matched with *** ETR among matched Asians and Caucasians was 81% and 56% respectively（P=0.003）,while the SVR rates were 73% and 36%（P 〈0.001） *** difference remained significant after adjusting for other predictive variables. CONCLUSION： Genotype 1 CHC in Asian subjects is associated with higher rates of virological response compared to that in Caucasians.

关键词： Hepatitis C Treatment Asians Retro-spective studies Comparative study Interferon Ribavirin Statistical data analysis

How to Tailor Porous Boron Nitride Properties for Applications in Interfacial Processes

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Accounts of Materials Research 2023年第2期4卷 143-155页

作者： Ioanna Itskou anouk L’Hermitte Sofia Marchesini Tian Tian Camille Petit Barrer Centre Department of Chemical EngineeringImperial College LondonLondon SW72AZUnited Kingdom Barrer Centre Department of Chemical Engineering and Department of MaterialsImperial College LondonLondon SW72AZUnited Kingdom National Physical Laboratory Teddington TW110LWUnited Kingdom

The research of new porous materials for applications in interfacial processes is key to addressing global energy and sustainability *** example,porous materials can be used to store fuels such as hydrogen or methane or to separate chemical mixtures reducing the energy currently required by thermal separation *** catalytic properties can be exploited to convert adsorbed molecules into valuable or less hazardous chemicals,thereby reducing energy consumption or pollutants *** boron nitride(BN)has appeared as a promising material for applications in molecular separations,gas storage,and catalysis owing to its high surface area and thermal stability,as well as its tunable physical properties and ***,the production of porous BN is still limited to the laboratory scale,and its formation mechanism,as well as ways to control porosity and chemistry,are yet to be fully *** addition,studies have pointed toward the instability of porous BN materials when exposed to humidity,which could significantly impact performance in industrial *** on porous BN performance and recyclability when employed in adsorption,gas storage,and catalysis remain limited,despite encouraging preliminary ***,porous BN powder must be shaped into macrostructures(e.g.,pellets)to be used ***,common methods to shape porous materials into macrostructures often cause a reduction in the surface area and/or mechanical *** recent years,research groups,including ours,have started addressing the challenges discussed ***,we summarize our collective findings through a selection of key ***,we discuss the chemistry and structure of BN,clarifying confusion around terminology and discussing the hydrolytic instability of the material in relation to its structure and *** demonstrate a way to reduce the instability in water while still maintaining high specific surface *** propose

关键词： separation Porous catalysis

Children’s growth and motor development following a severe burn:a systematic review

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Burns & Trauma 2023年第1期11卷 349-360页

作者： Maxime D.Cuijpers Martin G.A.Baartmans Paul P.M.van Zuijlen Johannes C.F.Ket anouk Pijpe Red Cross Hospital Burn Centre BeverwijkVondellaan 13BeverwijkThe Netherlands Amsterdam University Medical Centre Location VU University Medical CentreDepartment of PlasticReconstructiveand Hand SurgeryAmsterdam Movement Sciencesde Boelelaan 1117AmsterdamThe Netherlands Association of Dutch Burn Centres Zeestraat 27-29BeverwijkThe Netherlands Maasstad Hospital Department of PaediatricsMaasstadweg 21Rotterdam3079 DZThe Netherlands Red Cross Hospital Department of Plastic SurgeryReconstructive and Hand SurgeryVondellaan 13Beverwijk1942 LEThe Netherlands Paediatric Surgical Centre Emma Children’s HospitalAmsterdam UMCUniversity of AmsterdamVrije UniversiteitMeibergdreef 9Amsterdam1105 AZThe Netherlands Medical Library Vrije Universiteitde Boelelaan 1117AmsterdamThe Netherlands

Background:The epidemiological data on post-burn growth,body composition and motor devel-opment is ambiguous and *** aim of this systematic review was therefore to summarize the current body of evidence on post-burn growth,body composition and motor development in ***:A literature search was conducted in PubMed,EMBASE and Web of Science up to March *** considered observational studies that reported(1)metrics on weight,height,body composition,bone mineral content,bone mineral density or motor development,in(2)paediatric burn patients and(3)published in a peer-reviewed ***:A total of 16 studies were *** of the included studies used quantitative methods,but with differing methodology:prospective cohort studies(n=8),retrospective chart reviews(n=3),case-control studies(n=2),cross sectional studies(n=2)and a retrospective cohort study(n=1).When combined,the included studies represented 2022 paediatric burn patients,with a mean age of 7.7(±3.2)*** average burn sizewas 52.8%(±12.7)of the total body surface *** outcome measures included weight(n=12),height(n=7),muscular strength(n=4),bone mineral content(n=5),bone mineral density(n=5),body mass index(n=3),fat mass(n=5),lean body mass(n=7)and fine and gross motor development(n=1).Conclusions:Following an initial decline,patients’growth and motor development started to recover during the first or second year ***,burns may have a profound and prolonged effect on the paediatric burn patients’muscular strength,bone mineral content and lean body *** should be noted that the vast majority of studies included only patients with burns covering≥30%total body surface *** evidence presented in this review may thus not be representative of the whole paediatric burn population.

关键词： Burns Children Weight Height Bone Muscle Motor function

Gastric emptying evaluation by ultrasound prior colonoscopy:An easy tool following bowel preparation

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World Journal of Gastroenterology 2014年第37期20卷 13591-13598页

作者： Romain Coriat Vanessa Polin Ammar Oudjit Franck Henri Marion Dhooge Sarah Leblanc Chantal Delchambre anouk Esch Tessa Tabouret Maximilien Barret Frédéric Prat Stanislas Chaussade Gastroenterology unit and endoscopy unit Université Paris DescartesSorbonne Paris CitéFaculté de MédecineH?pital CochinAssistance Publique?pitaux de Paris (AP-HP) Radiology Department H?pital CochinAssistance Publique-H?pitaux de Paris (AP-HP) Laboratoires Mayoly Spindler

AIM: To investigate the gastric emptying after bowel preparation to allow general anaesthesia.

关键词： Colonoscopy Preparation Ultrasound Gastric emptying

Detection of circulating tumor cells in blood of pancreatic ductal adenocarcinoma patients

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Cancer Drug Resistance 2020年第1期3卷 83-97页

作者： Andrea Mayado Alberto Orfao anouk Mentink Maria Laura Gutierrez Luis Muñoz-Bellvis Leon W.M.M.Terstappen Cancer Research Center(IBMCC-CSIC/USAL-IBSAL) Cytometry Service(NUCLEUS)and Department of MedicineUniversidad de SalamancaSalamanca 37007Spain Centro de Investigación Biomédica en Red de Cáncer(CIBER-ONC)CB16/12/00400 Instituto de Salud Carlos IIIMadrid 28029Spain Department of Medical Cell BioPhysics University of TwenteEnschede 7522The Netherlands Division of General and Gastrointestinal Surgery University Hospital of Salamanca(CAUSA)and Department of SurgeryUniversidad de Salamanca and IBSALSalamanca 37007Spain

Aim:Previous studies suggest that circulating tumor cells(CTC)are present at very low frequencies in blood of pancreatic cancer(PC)***,no technique has proven efficient for their detection,in part due to the lack of accurate tumor ***,we evaluated the potential utility of two marker candidates-Mucin 16(MUC16)and Tetraspanin 1(TSPAN1)-identified through a detailed review of the ***:To evaluate the pattern of expression of both markers in pancreatic tumor cells *** blood,we used cell lines derived from pancreatic cancer patients and blood from healthy ***:Antibodies against both MUC16 and TSPAN1 showed expression in three pancreatic cancer(PC)cell lines while they were absent in blood *** evaluate the efficiency of isolating tumor cells from blood,PC cell lines were spiked at different frequencies in blood,sequentially stained with biotin-conjugated TSPAN1 and MUC16 antibodies and a streptavidin ferrofluids,followed by immunomagnetic *** recovery of spiked TSPAN1+tumor cells was high with limited contamination by *** contrast,no PC cells were isolated when the biotin MUC16 reagent was used because the biotin-conjugated clone did not recognize PC ***:The combination of MUC16,TSPAN1,and epithelial cell adhesion molecule(EpCAM)antibodies will likely increase the efficiency of capturing circulating tumor cell in blood of pancreatic ductal *** further develop a protocol for isolation of circulating tumor cell in blood of PC patients,high amounts of antibodies(5-10 mg)against EpCAM,MUC16,and TSPAN1 will be needed.

关键词： Pancreatic ductal adenocarcinoma circulating biomarkers circulating tumor cells

Tepid antegrade intermittent blood cardioplegia as an alternative for intermittent crossclamping with Lidoflazine

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World Journal of Cardiovascular Diseases 2013年第7期3卷 454-457页

作者： Sofia Kalantary anouk de Bruyn Steven Laga Inez Rodrigus Department of Cardiac Surgery Antwerp University Hospital Antwerp Belgium University of Antwerp Antwerp Belgium

Background: Blood cardioplegia is a technique with many variations in its use. Intermittent cross clamping with Lidoflazine has proven to deliver good cardioprotection in our center. Question: Is tepid (32°C) antegrade intermittent blood cardioplegia an efficient, safe and easy-to-use alternative to intermittent cross-clamping with Lidoflazine in elective isolated CABG in low-risk patients? Primary outcomes are heart enzymes (cTnI, CK-MB). Secondary outcomes are operation times, length of hospital stay, major complications and in-hospital mortality. Methods: From January 2012 until November 2012, 40 patients with LVEF ≥50%, EuroSCORE

关键词： Blood Cardioplegia Intermittent Cross Clamping Lidoflazine Myocardial Protection

Hepatitis C virus treatment with glecaprevir and pibrentasvir in patients co-prescribed carbamazepine:Three case reports

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2023年第4期14卷 33-38页

作者： Michael Braude Dilip T Ratnam Louise Marsh Joshua H Abasszade anouk T Dev Department of Gastroenterology and Hepatology Monash HealthClayton 3168VICAustralia General Practice Margaret River Medical CentreMargaret River 6285Australia

BACKGROUND Highly effective and well-tolerated direct-acting antiviral(DAA)therapies have revolutionised the management of hepatitis C virus(HCV);however,niche populations face treatment *** co-prescribed with several firstgeneration anti-epileptic drugs(AEDs)are contraindicated due to drug-drug interactions.A common example is carbamazepine whereby steady-state carbamazepine reduces the maximum concentration and area under the curve of velpatasvir,glecaprevir and pibrentasvir due to potent cytochrome P450(CYP)3A4 *** also induces P-glycoprotein which reduces glecaprevir and pibrentasvir’s area under curve to infinite *** and glecaprevir-pibrentasvir are contraindicated in patients who are co-prescribed carbamazepine due to the risk of reduced DAA therapeutic effect and consequently,virological treatment *** presents a challenge for patients in whom carbamazepine substitution is medically unfeasible,impractical or ***,the properties of current generation DAA therapies,including high-potency non-structural protein 5A inhibitory effect,may be sufficient to overcome reduced bioavailability arising from carbamazepine related CYP 3A4 and P-glycoprotein *** SUMMARY We present a case series of three patients with non-cirrhotic,treatment-naïve,genotype 1a,1b,and 3a HCV who were treated with a 12 wk course of glecaprevir-pibrentasvir,while co-prescribed carbamazepine for seizure ***-pibrentasvir combination therapy was chosen due to its potent in vitro activity and low barrier to pan-genotypic resistance associated *** therapy was dose-separated from carbamazepine to maximise time to peak concentration,and taken with meals to improve *** virological response at 12 wk was achieved in each patient with no adverse *** DAA therapies,including glecaprevir-pibrentasvir,warrant consideration as a therapeutic agent in people with HCV w

关键词： Antiepileptic drugs Drug interactions Hepatitis C virus Sustained virological response Health care access Case repor

Risk factors for overuse injuries in short-and long-distance running: A systematic review

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Journal of Sport and Health Science 2021年第1期10卷 14-28,I0001页

作者： Dennis van Poppel Maarten van der Worp anouk Slabbekoorn Sylvia S.P.van den Heuvel Marienke van Middelkoop Bart W.Koes Arianne P.Verhagen Gwendolyne G.M.Scholten-Peeters Research Group Diagnostics Avans University of Applied SciencesBreda4818 CRthe Netherlands Stichting Academie Instituut Fysiotherapie PLUS Utrecht3581 MDthe Netherlands Nederlands Paramedisch Institute Amersfoort3818 LAthe Netherlands Department of General Practice Erasmus MC Medical University CenterRotterdam3015 CEthe Netherlands Center for Muscle and Joint Health University of Southern DenmarkOdense5230Denmark Discipline of Physiotherapy Graduate School of HealthUniversity of TechnologySydneyChippendale NSW 2008Australia Department of Human Movement Sciences Faculty of Behavioral and Movement SciencesVrije Universiteit AmsterdamAmsterdam1081 HVthe Netherlands

Purpose:The aim of this study was to review information about risk factors for lower extremity running injuries in both short-distance(mean running distance-20 km/week and-10 km/session)and long-distance runners(mean running distance>20 km/week and>10 km/session).Methods:Electronic databases were searched for articles published up to February *** cohort studies using multivariable analysis for the assessment of individual risk factors or risk models for the occurrence of lower extremity running injuries were *** reviewers independently selected studies for eligibility and assessed risk of bias with the Quality in Prognostic Studies *** GRADE approach was used to assess the quality of the ***:A total of 29 studies were included:17 studies focused on short-distance runners,11 studies focused on long-distance runners,and 1 study focused on both types of runners.A previous running-related injury was the strongest risk factor for an injury for long-distance runners,with moderate-quality *** injuries not attributed to running was the strongest risk factor for an injury for short-distance runners,with high-quality *** body mass index,higher age,sex(male),having no previous running experience,and lower running volume were strong risk factors,with moderate quality evidence,for short-distance ***-quality evidence was found for all risk models as predictors of runningrelated injuries among short-and long-distance ***:Several risk factors for lower extremity injuries have been identified among short-and long-distance runners,but the quality of evidence for these risk factors for running-related injuries is *** injuries seem to have a multifactorial origin both in short-and long-distance runners.

关键词： Musculoskeletal health Protective factors Running-related injury