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Food intolerance and the few-foods(or oligoantigenic)diet in children with attention-deficit hyperactivity disorder

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Food Science and Human Wellness 2024年第4期13卷 1729-1738页

作者： Klaus W.lange Andreas Reissmann Yukiko Nakamura Katharina M.lange Faculty of Human Sciences University of RegensburgRegensburg 93040Germany Department of Psychology University of BathBath BA27AYUnited Kingdom

The hypothesis that some children with attention-deficit hyperactivity disorder(ADHD)may show sensitivity or allergic reactions to various food items has led to the development of the the few-foods(or oligoantigenic)*** rationale of the diet is to eliminate certain foods from the diet in order to exclude potential allergens contained either naturally in food or in artificial ingredients with allergenic *** oligoantigenic diet attempts to identify individual foods to which a person might be ***,ADHD symptoms are monitored while multiple foods are excluded from the ***,if symptoms remit,foods are re-introduced,while observing the individual for the return of *** advantage of the oligoantigenic diet is that it can be tailored to the individual.A growing body of evidence suggests that behavioral symptoms of subgroups of children with ADHD may benefit from the elimination of certain *** effect sizes of an oligoantigenic diet regarding improvement of ADHD symptoms have been found to be medium to *** evidence suggests that the investigation of the role of food hypersensitivities in ADHD is a promising avenue worthy of further *** large-scale,randomized controlled studies including assessment of long-term outcome are therefore warranted.

关键词： Attention-deficit hyperactivity disorder Food intolerance Few-foods diet Etiology Treatment

Learning about good nutrition with the 5-color front-of-package label"Nutri-Score":an experimental study

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Food Science and Human Wellness 2024年第3期13卷 1195-1200页

作者： Robin C.Hau Klaus W.lange University of Applied Sciences Landshut Landshut 84036Germany Faculty of Human Sciences University of RegensburgRegensburg 93040Germany

The Nutri-Score is a 5-color front-of-pack nutrition label designed to provide consumers with an easily understandable guideline to the healthiness of food *** impact that the Nutri-Score may have on consumers'choices is unclear since different experimental paradigms have found vastly different effect *** the present study,we have investigated how student participants change a hypothetical personal 1-daydietary plan after a learning phase during which they learn about the Nutri-Scores of the available food *** were instructed to compose a healthy diet plan in order that the question of whether the NutriScore would improve their ability to compose a healthy dietary plan could be investigated,independent of the question of whether they would apply this knowledge in their ordinary *** found a substantial(Cohen's d=0.86)positive impact on nutritional quality(as measured by the Nutrient Profiling System score of the Food Standards Agency)and a medium-sized(Cohen's d=0.43)reduction of energy *** content reduction was larger for participants who had initially composed plans with higher energy *** results suggest that the Nutri-Score has the potential to guide consumers to healthier food *** remains unclear,however,whether this potential will be reflected in real-life dietary choices.

关键词： Nutri-Score Front-of-package label Nudge Nutrition Health

Visible Light Indoor Positioning System Based on Pisarenko Harmonic Decomposition and Neural Network

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Chinese Journal of Electronics 2024年第1期33卷 195-203页

作者： Li ZHAO Yi REN Qi WANG lange DENG Feng ZHANG School of Electronic Information Engineering Xi’an Technological University

Visible-light indoor positioning is a new generation of positioning technology that can be integrated into smart lighting and optical communications. The current received signal strength(RSS)-based visible-light positioning systems struggle to overcome the interferences of background and indoor-reflected noise. Meanwhile, when ensuring the lighting, it is impossible to use the superposition of each light source to accurately distinguish light source information; furthermore, it is difficult to achieve accurate positioning in complex indoor environments. This study proposes an indoor positioning method based on a combination of power spectral density detection and a neural network. The system integrates the mechanism for visible-light radiation detection with RSS theory, to build a back propagation neural network model fitting for multiple reflection channels. Different frequency signals are loaded to different light sources at the beacon end, and the characteristic frequency and power vectors are obtained at the location end using the Pisarenko harmonic decomposition method. Then, a complete fingerprint database is established to train the neural network model and conduct location tests. Finally, the location effectiveness of the proposed algorithm is verified via actual positioning experiments. The simulation results show that, when four groups of sinusoidal waves with different frequencies are superimposed with white noise, the maximum frequency error is 0.104 Hz and the maximum power error is 0.0362 W. For the measured positioning stage, a 0.8 m × 0.8 m × 0.8 m solid wood stereoscopic positioning model is constructed, and the average error is 4.28 cm. This study provides an effective method for separating multi-source signal energies, overcoming background noise, and improving indoor visible-light positioning accuracies.

关键词： Neural networks Measurement uncertainty Position measurement Harmonic analysis Light emitting diodes Frequency estimation Indoor positioning systems

Observing the collapse of super-Bloch oscillations in strong-driving photonic temporal lattices

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Advanced Photonics 2024年第4期6卷 14-24页

作者： Xinyuan Hu Shulin Wang Chengzhi Qin Chenyu Liu lange Zhao Yinglan Li Han Ye Weiwei Liu Stefano Longhi Peixiang Lu Bing Wang Huazhong University of Science and Technology School of Physics Wuhan National Laboratory for Optoelectronics Wuhan Institute of Technology Hubei Key Laboratory of Optical Information and Pattern Recognition Politecnico di Milano Dipartimento di Fisica IFISC (UIB-CSIC) Instituto de Fisica Interdisciplinary Sistemas Complejos

Super-Bloch oscillations(SBOs) are amplified versions of direct current(dc)-driving Bloch oscillations realized under the detuned dc-and alternating current(ac)-driving electric fields. A unique feature of SBOs is the coherent oscillation inhibition via the ac-driving renormalization effect, which is dubbed as the collapse of SBOs. However, previous experimental studies on SBOs have only been limited to the weak ac-driving regime, and the collapse of SBOs has not been observed. Here, by harnessing a synthetic temporal lattice in fiber-loop systems, we push the ac-field into a strong-driving regime and observe the collapse of SBOs, which manifests as the oscillation-trajectory localization at specific ac-driving amplitudes and oscillation-direction flip by crossing collapse points. By adopting arbitrary-wave ac-driving fields, we also realize generalized SBOs with engineered collapse conditions. Finally, we exploit the oscillation-direction flip features to design tunable temporal beam routers and splitters. We initiate and demonstrate the collapse of SBOs, which may feature applications in coherent wave localization control for optical communications and signal processing.

关键词： Electric fields Optical modulators Phase modulation Bessel functions Optical coherence Polarization Pulse signals Solids Physical coherence Signal processing

Supercritical fluid technology as a sustainable alternative method for textile dyeing:An approach on waste,energy,and CO_(2)emission reduction

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Journal of Environmental Sciences 2024年第6期140卷 123-145页

作者： Carlos Rafael Silva de Oliveira Patrícia Viera de Oliveira Leandro Pellenz Catia Rosana lange de Aguiar Afonso Henrique da Silva Júnior Federal University of Santa Catarina Textile Engineering Department2514 João Pessoa St.BlumenauSC89036-004Brazil Federal University of Santa Catarina Chemical Engineering DepartmentS/n Biotério Central St.FlorianópolisSC88040-900Brazil

The clothing industry is considered one of the most polluting industries on the planet due to the high consumption of water,energy,chemicals/dyes,and high generation of solid waste and *** with environmental concerns,the textile ennoblement sector is the most critical of the textile production chain,especially the traditional dyeing *** an alternative to current problems,dyeing with supercritical CO_(2)(scCO_(2))has been presented as a clean and efficient process for a sustainable textile *** fluid dyeing(SFD)has shown a growing interest due to its significant impact on environmental preservation and social,economic,and financial *** main SFD benefits include economy and reuse of non-adsorbed dyes;reduction of process time and energy expenditure;capture of atmospheric CO_(2)(greenhouse gas);use and recycling of CO_(2)in SFD;generation of carbon credits;water-free process;effluent-free process;reduction of CO_(2)emission and auxiliary *** being still a non-scalable and evolving technology,SFD is the future of *** review presented a comprehensive overview of the environmental impacts caused by traditional processes and confronted the advantages of *** SFD technique was introduced,along with its latest advances and future *** and environmental gains were also discussed.

关键词： Textile industry Supercritical dyeing Sustainable processes Water free dyeing Energy saving Cleaner production

Monogenic features of urolithiasis: A comprehensive review

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Asian Journal of Urology 2024年第2期11卷 169-179页

作者： Kyo Chul Koo Abdulghafour Halawani Victor K.F.Wong Dirk lange Ben H.Chew Department of Urology Yonsei University College of MedicineSeoulRepublic of Korea Department of Urology King Abdulaziz UniversityJeddahSaudi Arabia Department of Urological Sciences University of British ColumbiaStone Centre at Vancouver General HospitalVancouverBritish ColumbiaCanada

Objective: Urolithiasis formation has been attributed to environmental and dietary factors. However, evidence is accumulating that genetic background can contribute to urolithiasis formation. Advancements in the identification of monogenic causes using high-throughput sequencing technologies have shown that urolithiasis has a strong heritable ***: This review describes monogenic factors implicated in a genetic predisposition to urolithiasis. Peer-reviewed journals were evaluated by a PubMed search until July 2023 to summarize disorders associated with monogenic traits, and discuss clinical implications of identification of patients genetically susceptible to urolithiasis ***: Given that more than 80% of urolithiases cases are associated with calcium accumulation, studies have focused mainly on monogenetic contributors to hypercalciuric urolithiases, leading to the identification of receptors, channels, and transporters involved in the regulation of calcium renal tubular reabsorption. Nevertheless, available candidate genes and linkage methods have a low resolution for evaluation of the effects of genetic components versus those of environmental, dietary, and hormonal factors, and genotypes remain undetermined in the majority of urolithiasis ***: The pathophysiology underlying urolithiasis formation is complex and multifactorial, but evidence strongly suggests the existence of numerous monogenic causes of urolithiasis in humans.

关键词： Gene Genetic expression Inheritance pattern Urolithiasis

Assessment of the piroxicam-incited model of synchronized colitis in T-cell receptor alpha chain-deficient mice

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Animal Models and Experimental Medicine 2024年第4期7卷 533-543页

作者： Maximo E.lange Danisa M.Bescucci Valerie F.Boras Tony Montina G.Douglas Inglis douglas inglis 11 lethbridge research and development centre agriculture and agri-food canadalethbridgealbertacanada alberta health services chinook regional hospitallethbridgealbertacanada department of chemistry and biochemistry university of lethbridgelethbridgealbertacanada southern alberta genome sciences centre university of lethbridgelethbridgealbertacanada

Background:A multitude of mouse models are utilized to emulate and study intestinal inflammation.T-cell receptor alpha chain(TCRα)-deficient mice are used as a model of spontaneous colitis that has similarities with human ulcerative ***,colitis is triggered late in the life of the mouse(age:4-5 months),and inflammation does not develop at the same time in different mice.A previously conducted study reported that the administration of the drug piroxicam triggered predictable and early colitis in TCRα-deficient mice at the age of 6-8 ***,a detailed characterization of ensuing inflammation was not ***:We conducted an in-depth examination of piroxicam-triggered colitis in TCRα-deficient mice,with emphasis on spatial histopathologic changes and analysis of expression of inflammatory ***,we tested amelioration of colitis with ***:We confirmed that piroxicam induced a time-prescribed colitis and did so in the proximal colon as well as the cecum of TCRα-deficient *** adminis-tration was observed to induce epithelial hyperplasia,goblet cell loss,and leukocyte infiltration with occasional ulceration.A Swiss roll technique was used to examine the colon and cecum in its ***,we observed that inflammation was mul-tifocal segmental,with areas of tissue damage in between healthy *** addition,we observed variability in the severity of inflammation among replicate animals and treatments,and that the administration of dexamethasone only partially ameliorated inflammation in the proximal ***:Piroxicam consistently induced multifocal segmental colitis in the proxi-mal colon and cecum,although the degree of inflammation was reduced in the ***,spatial variability in inflammation in the large intestine and the inter-replicate variation in the severity of inflammation must be taken into consideration when utilizing this murine model of synchronized colitis.

关键词： colon dexamethasone histology induction inflammation knockout

Ornithine aspartate effects on bacterial composition and metabolic pathways in a rat model of steatotic liver disease

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World Journal of Hepatology 2024年第5期16卷 832-842页

作者： Elisa Carolina lange Pabulo Henrique Rampelotto Larisse Longo Laura Bainy Rodrigues de Freitas Carolina Uribe-Cruz Mario Reis Alvares-da-Silva Experimental Laboratory of Hepatology and Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil Graduate Program in Gastroenterology and Hepatology Universidade Federal do Rio Grande do SulPorto Alegre 90035-007Brazil Bioinformatics and Biostatistics Core Facility Universidade Federal do Rio Grande do SulPorto Alegre 91501-970Brazil Graduate Program in Biological Sciences:Pharmacology and Therapeutics Universidade Federal do Rio Grande do SulPorto Alegre 90035-007Brazil Facultad de Ciencias de la Salud Universidad Católica de las MisionesPosadasMisiones 3300Argentina Division of Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007RSBrazil Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq)researcher Brasília 71605-001Brazil

BACKGROUND Metabolic-dysfunction associated steatotic liver disease(MASLD)is a hepatic manifestation of metabolic *** suggest ornithine aspartate(LOLA)as drug *** To analyze the influence of LOLA intake on gut microbiota using a nutritional model of *** Adult male Sprague Dawley rats were randomized into three groups:Control(10 rats fed with a standard diet),MASLD(10 rats fed with a high-fat and choline-deficient diet),and LOLA(10 rats receiving 200 mg/kg/d LOLA,after the 16th week receiving high-fat and choline-deficient diet).After 28 wk of the experiment,animals were euthanized,and feces present in the intestine were *** fecal DNA extraction,the V4 region of the 16S rRNA gene was amplified followed by sequencing in an Ion S5™*** Alpha and beta diversity metrics were comparable between MASLD and LOLA.3 OTUs were differentially abundant between MASLD and LOLA,which belong to the species Helicobacter rodentium,Parabacteroides goldsteinii,and Parabacteroides *** functional prediction provided two different metabolic profiles between MASLD and *** 9 pathways differentially abundant in MASLD are related to a change in energy source,adenosine/purine nucleotides degradation as well as guanosine and adenosine deoxyribonucleotides *** 14 pathways differentially abundant in LOLA are associated with four major metabolic functions primarily influenced by L-aspartate,including tricarboxylic acid cycle pathways,purine/guanosine nucleotides biosynthesis,pyrimidine ribonucleotides biosynthesis and salvage as well as lipid IVA *** Although LOLA had no influence on alpha and beta diversity in this nutritional model of MASLD,it was associated with changes in specific gut microbes and their related metabolic pathways.

关键词： Animal model Gut microbiota Metabolic-associated steatotic liver disease Metabolic prediction Ornithine aspartate

中国社会陌生人之间合作行为的变迁:基于社会困境研究的元分析(1999~2019)

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心理学报 2024年第9期56卷 1159-1175页

作者：苑明亮伍俊辉金淑娴林靓寇彧 Paul A.M.Van lange 安徽农业大学人文社会科学学院心理学系合肥230036 中国科学院心理研究所行为科学重点实验室北京100101 中国科学院大学心理学系北京100049 萨塞克斯大学心理学院英国布莱顿BN19RH 北京师范大学发展心理研究院应用实验心理北京市重点实验室心理学国家级实验教学示范中心(北京师范大学)北京100875 阿姆斯特丹自由大学脑与行为研究院实验与应用心理学系荷兰阿姆斯特丹1081BT

陌生人间的合作行为对于解决社会公共问题,应对世界百年未有之大变局意义重大。本研究采用横断历史元分析方法,基于1999~2019年间开展的254项使用社会困境范式测量我国陌生人间合作行为的研究(共302个合作率,29249名被试,平均年龄:18~28... 详细信息

陌生人间的合作行为对于解决社会公共问题,应对世界百年未有之大变局意义重大。本研究采用横断历史元分析方法,基于1999~2019年间开展的254项使用社会困境范式测量我国陌生人间合作行为的研究(共302个合作率,29249名被试,平均年龄:18~28岁),探讨了中国社会中合作行为的变迁及一些社会发展指标在其中的解释作用,并比较中美两国的合作行为变迁趋势。结果表明,中国人的合作行为水平随时间而上升,一些社会发展指标(人均国内生产总值、城市化率、高等教育水平、互联网普及率等)可能是其上升的社会变迁基础。中美两国合作行为表现出相似的上升趋势,但中国的在更短时间内有更大上升幅度。研究结果对提振民众信心具有重要意义。

关键词：合作行为社会资本社会困境横断历史元分析社会变迁