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CAutoCSD-Evolutionary Search and optimisation Enabled Computer Automated Control System Design

International Journal of Automation and computing 2004年第1期1卷 76-88页

作者： Kiam Heong ang gregory C.Y. Kay Chen Tan Hiroshi Kashiwagi Department of Electronics and Electrical Engineering University of glasgow Glasgow G12 8LT UKDepartment of Electronics and Electrical Engineering University of Glasgow Glasgow G12 8LT UKDepartment of Electronics and Electrical Engineering University of Glasgow Glasgow G12 8LT UKDepartment of Mechanical Engineering and Material Science Kumamoto University Japan

This paper attempts to set a unified scene for various linear time-invariant (LTI) control system design schemes, by transforming the existing concept of “computer-aided control system design” (CACSD) to novel “computer-automated control system design” (CAutoCSD). The first step towards this goal is to accommodate, under practical constraints, various design objectives that are desirable in both time and frequency domains. Such performance-prioritised unification is aimed at relieving practising engineers from having to select a particular control scheme and from sacrificing certain performance goals resulting from pre-commitment to such schemes. With recent progress in evolutionary computing based extra-numeric, multi-criterion search and optimisation techniques, such unification of LTI control schemes becomes feasible, analytical and practical, and the resultant designs can be creative. The techniques developed are applied to, and illustrated by, three design problems. The unified approach automatically provides an integrator for zero-steady state error in velocity control of a DC motor, and meets multiple objectives in the design of an LTI controller for a non-minimum phase plant and offers a high-performance LTI controller network for a non-linear chemical process.

关键词： Linear time invariant (LTI) proportional plus integral plus derivative (PID) control system design (CSD) computer aided control system design (CACSD) performance index genetic algorithms (gA) evolutionary computation (EC) process control r

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优质番茄新品种青恋521的选育

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中国瓜菜 2024年第2期37卷 128-132页

作者：史小强胡京昂张丽霞张颜巩彪张冰周涛郑州市农业科技研究院郑州450015 山东农业大学山东泰安271018 河南农业职业学院河南中牟451450 中国农业大学北京100193

青恋521是以D3-8-5为母本、TB1430-3-7为父本选育而成的无限生长型早熟番茄杂交1代新品种。该品种植株生长势强,普通花叶,叶色深绿,7~8节着生第1花序,花序间隔3片叶。中大果,幼果有绿果肩,成熟果粉色,果实圆形,硬度中,平均单果质量223 ... 详细信息

青恋521是以D3-8-5为母本、TB1430-3-7为父本选育而成的无限生长型早熟番茄杂交1代新品种。该品种植株生长势强,普通花叶,叶色深绿,7~8节着生第1花序,花序间隔3片叶。中大果,幼果有绿果肩,成熟果粉色,果实圆形,硬度中,平均单果质量223 g。维生素C含量(w,后同)15.68 mg﹒100 g^(-1),总酸含量0.35%,可溶性固形物含量5.0%,可溶性总糖含量3.48%,番茄红素含量78.5 mg·kg^(-1),鲜食酸甜可口,品质佳。对番茄黄化曲叶病毒(tomato yellow leaf curl virus,TYLCV)、黄瓜花叶病毒(cucumber mosaic virus,CMV)、番茄花叶病毒(tomato mosaic virus,TMV)、叶霉病、枯萎病及根结线虫病均有一定的抗性,综合抗性强。丰产性较好,平均667 m^(2)产量7563.4 kg。适宜于河南、山东、河北、陕西等地早春保护地及越冬温室种植。2021年获得农业农村部植物新品种权。

关键词：番茄新品种青恋521 优质

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发酵乳杆菌对灭菌豆浆中晚期糖化终末产物形成的影响

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食品研究与开发 2024年第6期45卷 9-15页

作者：张霖肖柯王文悦易弛余帆肖俊峰樊鑫朱晓青李琴周梦舟穆杨湖北工业大学生物工程与食品学院湖北武汉430068

豆浆含有优质蛋白质、必需脂肪酸和大量维生素,其经过巴氏杀菌或超高温处理会促进还原糖和蛋白质之间的糖基化反应,产生糖基化产物和晚期糖化终末产物(advanced glycation end products,AgEs),进而对人类健康造成威胁。为提高豆浆的品质... 详细信息

豆浆含有优质蛋白质、必需脂肪酸和大量维生素,其经过巴氏杀菌或超高温处理会促进还原糖和蛋白质之间的糖基化反应,产生糖基化产物和晚期糖化终末产物(advanced glycation end products,AgEs),进而对人类健康造成威胁。为提高豆浆的品质,该文利用发酵乳杆菌(Lactobacillus fermentum)发酵豆浆,探究发酵乳杆菌对灭菌豆浆AgEs含量的影响。结果表明,经***发酵灭菌后的豆浆,荧光强度降低12%~17%。发酵豆浆可减少羰基化对蛋白二级结构的破坏,α-螺旋转变成β-折叠和无规卷曲。同时,发酵使灭菌豆浆的异黄酮含量从274.43μg/mL提升至351.83μg/mL;发酵乳杆菌发酵豆浆与豆浆相比,可显著提高抗氧化活性。综上所述,乳酸菌可抑制食品加工过程中AgEs的形成。

关键词：发酵豆浆发酵乳杆菌蛋白二级结构异黄酮生物转化蛋白非酶糖化反应

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氢溴酸加兰他敏在小鼠血浆、脑组织中的药物动力学研究

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中国医药工业杂志 2006年第5期37卷 332-334页

作者：陈昂贺芬上海医药工业研究院上海200437

建立了HPLC-荧光法测定小鼠血浆和脑组织中氢溴酸加兰他敏的浓度。采用IntersilC18柱,流动相为甲醇-水(40∶60,含0.2%三乙胺,磷酸调至pH6.4),激发波长和发射波长分别为290和320nm。小鼠单剂量口服氢溴酸加兰他敏4mg/kg后血浆和脑组织中... 详细信息

建立了HPLC-荧光法测定小鼠血浆和脑组织中氢溴酸加兰他敏的浓度。采用IntersilC18柱,流动相为甲醇-水(40∶60,含0.2%三乙胺,磷酸调至pH6.4),激发波长和发射波长分别为290和320nm。小鼠单剂量口服氢溴酸加兰他敏4mg/kg后血浆和脑组织中的药物动力学参数tmax均为0.5h,Cmax分别为(691±80.34)和(1402±230.46)μg/L,AUC0→12h分别为(1138.2±160.5)和(2787.7±212.4)μg·h·L-1,AUC0→∞分别为(1147.01±198.94)和(2829.06±171.99)μg·h·L-1,t1/2分别为(4.6±1.4)和(5.0±0.2)h。

关键词：加兰他敏药物动力学高效液相色谱

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ERoD activities of liver in Mugil so-iuy exposed to benzo(a)pyrene,pyrene and their mixture

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Acta oceanologica Sinica 2003年第2期22卷 213-220页

作者： WangChonggang ChenJixin Yuang ZhengWeiyun Colleg.oflifescience XiamenUniversityXiamen361005China EnvironmentalScienceResearchCenter XiamenUniversityXiamen361005China

The effects on hepatic ERoD (7-ethoxyresorufin o-deethylase) in Mugil so-iuy exposedto benzo(a)pyrene (BaP), pyrene and their mixtures of equal concentration were investigated, at concentrations of 0.1, 1.0, 5.0, 10.0, 50.0μg/dm3, in experimental condition. Time-effects and dose-response of the biochemical indexs were observed. The results showed that the hepatic ERoD activities were induced by the exposure of BaP, pyrene and their mixtures at high concentration. Dose-response connections were that the hepatic ERoD activities were elevated with increasing concentration of the pollutants. The combined effect of BaP and pyrene at 1:1 concentration ratio on hepatic ERoD activity was antagonism.

关键词： ERoD activity benzo(a)pyrene(BaP),pyrene Mugil so-iuy

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Study on Extraction of Insoluble Dietary Fiber from Apple pulp

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Chinese Food Science 2012年第2期1卷 11-13页

作者： ang Lei LI Chao ZHU Dong CHEN Wei Tang Zhi-hua School of Chemical and Environment Science Shaanxi University of Technology

[ objective] To optimize the extraction conditions of insoluble dietary fiber from apple pulp. [ Method] The insoluble dietary fiber was ex-tracted from the apple pulp by alkaline, and the optimal extraction conditions were determined by orthogonal experiment. [ Result] The influential or-der of each factor on the extraction of insoluble fiber decreased in the order of solid-liquid ratio 〉 alkali concentration 〉 temperature 〉 extraction time, and the optimal extraction technology was A3 B1 C2 D2, that is, 1：11 （g/ml） of solid-liquid ratio, 0.25 mol/L alkaline concentration, 50 ℃ of extraction temperature and 2.0 h extraction time, under these conditions, the yield of insoluble dietary fiber was 35.46%. [ Conchsion] The apple pulp contains rich dietary fiber, and the insoluble dietary fiber extracted from the apple pulp has great development value. Key words Apple; Insoluble dietary fiber; Extraction technology; China

关键词： Apple Insoluble dietary fiber Extraction technology China

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催化式红外辐射对葡萄籽灭菌的影响

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中国食品学报 2019年第10期19卷 150-156页

作者：付瑞鹏王华张昂李华西北农林科技大学葡萄酒学院陕西杨凌712100 陕西省葡萄与葡萄酒工程研究中心陕西杨凌712100 西北农林科技大学葡萄与葡萄酒(合阳)试验站陕西合阳715300 秦皇岛出入境检验检疫局检验检疫技术中心河北秦皇岛066004

通过催化式红外辐射技术处理浸渍发酵后的葡萄籽,研究红外辐射联合保温处理对葡萄籽灭菌效果的影响。随着红外辐射时间和保温时间的延长,保温温度升高,葡萄籽中细菌总数迅速下降,其中红外辐射98s、75℃保温60min处理葡萄籽,灭菌效果最好... 详细信息

通过催化式红外辐射技术处理浸渍发酵后的葡萄籽,研究红外辐射联合保温处理对葡萄籽灭菌效果的影响。随着红外辐射时间和保温时间的延长,保温温度升高,葡萄籽中细菌总数迅速下降,其中红外辐射98s、75℃保温60min处理葡萄籽,灭菌效果最好,葡萄籽中细菌总数降到1.66 lg CFU/g,比单独红外辐射处理的葡萄籽降低43.14%,比未处理的葡萄籽降低了65.99%;葡萄籽表征红色程度的a^*值和表征黄色程度的b^*值分别为12.31~13.48和13.22~14.47,色差E值为2.14~5.26,表明葡萄籽处理前、后色泽差异小。葡萄籽油得率随着保温温度的升高和保温时间的延长而提高,其中葡萄籽油得率最高达10.39%,比未处理葡萄籽提高了46.96%。试验各处理提取的葡萄籽油酸值、过氧化值和碘值均符合联合国粮食及农业组织(FAo)对初榨葡萄籽油制定的标准。经综合评价,当红外辐射处理葡萄籽98 s、75℃保温处理60 min时,葡萄籽灭菌效果最好,葡萄籽油得率最高,葡萄籽的色泽保持较好。

关键词：葡萄籽红外辐射灭菌葡萄籽油

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用于变形机翼夹心式柔性伸缩蒙皮的梯形蜂窝支撑结构

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复合材料学报 2015年第3期32卷 815-822页

作者：沈元昂海松刘卫东南京航空航天大学机械结构力学与控制国家重点实验室南京210016

变形机翼技术的实现离不开柔性蒙皮技术的支持,提出了一种应用于变形机翼夹心式柔性伸缩蒙皮的面内褶皱型梯形蜂窝蒙皮支撑结构。通过理论分析研究了该支撑结构的面内伸缩特性,得到其面内横向无量纲化等效弹性模量大小与3个参数(形状系... 详细信息

变形机翼技术的实现离不开柔性蒙皮技术的支持,提出了一种应用于变形机翼夹心式柔性伸缩蒙皮的面内褶皱型梯形蜂窝蒙皮支撑结构。通过理论分析研究了该支撑结构的面内伸缩特性,得到其面内横向无量纲化等效弹性模量大小与3个参数(形状系数k、宽度系数t和高度系数h)之间的关系:其等效弹性模量随k增大而减小,随t增大而增大,随h增大而减小。利用ANSYS软件对其进行了有限元分析并通过实验对其面内力学特性进行了验证。结果表明:理论分析、有限元结果与实验结果基本吻合。通过选择合适的结构参数,其面内横向等效弹性模量可达到原材料弹性模量的10-4,比同等参数下手风琴式支撑结构的面内横向等效弹性模量更小,变形能力更强。相比传统蒙皮支撑结构,该结构可以减小变形过程中的驱动力与能量消耗,提高柔性蒙皮的变形效率。

关键词：变形机翼梯形蜂窝柔性蒙皮弹性模量有限元分析

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Multivariate and wavelet techniques of spontaneous electroencephalography and event related potentials during children maturation <br>—The role of phase resetting<br>

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Journal of Biomedical Science and Engineering 2013年第6期6卷 669-682页

作者： Catarina I. Barriga-Paulino angélica B. Flores Elena I. Rodríguez-Martínez Carlos Chinchilla Carlos M. gómez Human Psychobiology Laboratory Department of Experimental Psychology University of Seville Seville Spain

The purpose of this study is to analyze whether the maturation of spontaneous EEg.occurs at the same rate as Late Positive Component (LPC) maturation. To that end, the spontaneous EEg rhythms power spectral density (PSD) and the LPC component in a g.oup of children and a g.oup of young adults were obtained and analyzed by means of Spearman’s correlation coefficients, hierarchical clustering, Principal Component Analysis (PCA) and topographical analysis. The multivariate analysis revealed a co-maturation of LPC with the delta band. This co-maturation was more evident in the more posterior reg.on. The multivariate analysis results suggest that the maturation of the two components is temporally closely associated. The LPC in both children and young adults was produced by a combination of increase of Event Related Spectral Perturbation (ERSP) and phase resetting in the delta band. It can be suggested that the maturations of delta and LPC are functionally interdependent due to a possible origin of LPC as a delta phase resetting and/or because both processes depend on the same fraction of synaptic pruning.

关键词： Cerebral Maturation Late Positive Component P300 Delta Spontaneous EEg

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联合应用抗疟药治疗皮肤型皮肌炎的回顾性研究

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世界核心医学期刊文摘（皮肤病学分册） 2005年第11期1卷 23-24页

作者： ang g.C. Werth V.P. 王琼 Dr.Department of Dermatology 2 Rhoads Pavilion 36th and Spruce Philadelphia PA 19104 United States

objective: To observe whether the use of antimalarials in combination resulted in significant improvement in the cutaneous signs and symptoms of patients with dermatomyositis who did not otherwise respond to the use of single-agent antimalarial therapy. Design: Retrospective case series of 17 patients treated between January 1, 1991, and December 31, 2002. Setting: An ambulatory medical dermatology clinic in an academic center. Patients: Patients had adult-onset dermatomyositis with predominantly cutaneous symptoms and a follow-up period at our clinic of at least 6 months. Cases in which it was not possible to assess the effect of treatment on cutaneous symptoms were not included. Intervention: Treatment regimens varied and included the use of antimalarials, prednisone, methotrexate, and other medications. Main outcome Measures: Physician-observed and patient-reported improvement based on erythema, pruritus, and extent of affected skin. Results: Seven of 17 patients experienced at least near clearance in cutaneous symptoms with the use of antimalarial therapy alone: 4 of these patients required combination therapy (hydroxychloroquine sulfate-quinacrine hydrochloride or chloroquine phosphate-quinacrine),while 3 of them responded well to antimalarial monotherapy. The median time required to reach the response milestones on the final working therapeutic regimen was 3 months (mean, 4.8 months; range, 2-14 months). Six patients did not respond significantly to any type of therapy, including nonantimalarials. Conclusion: our experience suggests that a significant subg.oup of patients whose skin lesions have been unresponsive to a single antimalarial benefit from combination therapy with hydroxychloroquine and quinacrine or chloroquine and quinacrine, but controlled clinical trials are warranted to assess the extent of benefit.

关键词：皮肌炎抗疟药物皮肤型硫酸羟氯喹皮肤症状甲氨蝶呤病型临床对照试验磷酸氯喹亚群

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