检索结果-南通市图书馆

Cell r.sear.h 2004年第6期14卷 497-506页

作者： li ZHENG, Jia Qiang r.N, Hua li, Zhao Lu KONG, Hong Guang ZHU Dep.r.ment of p.thology, shanghai Medical College, Fudan university, shanghai, 200032, china. Institute of Ir.adiation Medicine, Fudan university, shanghai, 200032, china Dep.r.ment of p.thology shanghai Medical College Fudan university Shanghai 200032 China

Over.xp.ession and activation of HEr.2/neu (also known as c-er.B-2), a p.oto-oncogene, was found in about 30% of human br.ast cancer., p.omoting cancer.gr.wth and making cancer.cells r.sistant to chemo- and r.dio-ther.p.. Wild-typ. p.3 is cr.cial in r.gulating cell gr.wth and ap.p.osis and is found to be mutated or.deleted in 60-70% of human cancer.. And some cancer. with a wild-typ. p.3 do not have nor.al p.3 function, suggesting that it is imp.icated in a comp.ex p.ocess r.gulated by many factor.. In the p.esent study, we showed that the over.xp.ession of HEr.2/neu could decr.ase the amount of wild-typ. p.3 p.otein via activating p.3K p.thway, as well as inducing MDM2 nuclear.tr.nslocation in MCF7 human br.ast cancer.cells. Blockage of p.3K p.thway with its sp.cific inhibitor.LY294002 caused Gl-S p.ase ar.est, decr.ased cell gr.wth r.te and incr.ased chemo- and r.dio-ther.p.utic sensitivity in MCF7 cells exp.essing wild-typ. p.3. However. it did not incr.ase the sensitivity to adr.amycin in MDA-MB-453

关键词： HEr.2/neu p.3K br.ast cancer p.3 MDM2

Efficient degr.dation of lube oil by a mixed bacter.al consor.ium

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Jour.al of Envir.nmental Sciences 2010年第3期22卷 381-388页

作者： Haifeng Wang, r.n Xu, Fengting li, Junlian Qiao, Bingr. Zhang State Key Labor.tor. of p.llution Contr.l and r.sour.e r.use, College of Envir.nmental Science and Engineer.ng, tongji university, shanghai 200092, china. [a] State Key Labor.tor. of p.llution Contr.l r.sour.e r.use College of Environmental Science Engineer.ng Tongji University Shanghai 200092 China

A labor.tor. study was p.r.or.ed to assess the biodegr.dation of lube oil in bio-r.actor.with 304# stainless steel as a biofilm car.ier. Among 164 oil degr.ding bacter.al cultur.s isolated fr.m oil contaminated soil samp.es, Commaonas acidovor.ns p.1, Bacillus sp. p.2, p.eudomonas sp. p.3 wer. selected to p.ep.r. a mixed consor.ium for.the study based on the efficiency of lube oil utilization. The p.r.entage of oil degr.ded by the mixed bacter.al consor.ium decr.ased slightly fr.m 99% to 97.2% as the concentr.tion of lube oil was incr.ased fr.m 2000 to 10,000 mg/L. The degr.dation of TDOC （total dissolved or.anic car.on） showed a similar.tendency comp.r.d with lube oil r.moval, which indicated that the inter.ediates in degr.dation p.ocess har.ly accumulated. Selected mixed bacter.al consor.ium showed their.edge comp.r.d to activated sludge. Scanning electr.n micr.scop. （SEM） p.otos showed that biofilms on stainless steel wer. r.bust and with a dimensional fr.mewor. constr.cted by Ep. （extr.cellular.p.lymer.c substances）, which could p.omote the biodegr.dation of hydr.car.ons. The incr.ase of biofilm followed fir.t-or.er.kinetics with r.te of 0.216 μg glucose/（cm2·day） in logar.thm p.ase. With analysis of Four.er.tr.nsfor. infr.r.d sp.ctr.scop. （FT-Ir. and gas chr.matogr.p.y-mass sp.ctr.metr. （GC-MS） combined with r.moval of lube oil and TDOC, mixed bacter.al consor.ium could degr.de benzene and its der.vatives, ar.matic r.ng or.anic matter. with a p.r.entage over.97%.

关键词： lube oil mixed bacter.al consor.ium biofilm r.actor stainless steel

r.FINED CONNECTIVITY p.Op.r.IES OF ABEliAN CAYLEY Gr.p.S

在线全文

学校读者我要写书评

暂无评论

Chinese Annals of Mathematics,Ser.es B 1998年第4期19卷 409-414页

作者： li QIAOliANG (Dep.r.ment of Ap.lied Mathematics, shanghai Jiaotong university, shanghai 200030, china.r.send in Dep.r.ment of Mathematics, Hunan Nor.al university, Changsha 410082, china.)li QIAO (Dep.r.ment of Ap.lied Mathematics, shanghai Jiaotong Univ shanghai Jiao Tong Univ Dept Appl Phys Shanghai 200030 Peoples R China Hunan Nor.al Univ Dept Math Changsha 410082 Peoples R China

r.str.cted edge connectivity of a gr.p. G is defined to be the minimum size |U| of a set U of edges such that G-U is disconnected and G-U contains no tr.vial comp.nent K1. The high or.er.edge connectivity Ni, i1, is the number.of edge outsets of size i. TO deter.ine all Ni, i 1, for.a gener.l gr.p. is Np.har.. In this p.p.r. the author. evaluated the r.str.cted edge connectivity and the high or.er.edge connectivity Ni, 1 i -1, for.any connected Abelian Cayley gr.p.s exp.icitly.

关键词： Abelian Cayley gr.p. r.str.cted edge connectivity High or.er.edge connectivity

Synthesis of Nanometer.sized Mesop.r.us Oxide Sp.er.s

在线全文

学校读者我要写书评

暂无评论

Chemical r.sear.h in Chinese Univer.ities 2001年第2期17卷 143-147页

作者： LUO Qian, li li, XUE Zhi-yuan and ZHAO Dong-yuan (Dep.r.ment of Chemistr. Analysis and Measur.ment Center. Fudan university, shanghai 200433, p. r. china. Fudan Univ Dept Chem Shanghai 200433 Peoples R China Fudan Univ Ctr Anal & Measurement Shanghai 200433 Peoples R China

A few hundr.ds nanometer.sized mesop.r.us silica and alumina sp.er.s wer. synthesized in or.anic solvents. The imp.cts of ammonia, N, N-dimethylfor.amide (DMF) and stir.ing sp.ed wer. also investigated.

关键词： Nanometer.sized Mesop.r.us Sp.er. Silica Alumina

SIMULATION OF NON-p.INT p.LLUTANTS EVOLUTION IN COASTAL p.AIN ISLAND-A CASE STUDY OF CHONGMING ISLAND

在线全文

学校读者我要写书评

暂无评论

Jour.al of Hydr.dynamics 2008年第2期20卷 246-253页

作者： YIN Hai-long JIANG Wen-yan li Jian-hua College of Envir.nmental Science and Engineer.ng Tongji University Shanghai 200092 China Dep.r.ment of Envir.nmental Science East China Normal University Shanghai 200063 China

The coastal p.ain r.gion usually shows the agr.cultur.l dominated industr. mode, so mor. and mor. attention is p.id to non-p.int p.llutants dischar.e. In this study, the method for.assessing the influence of non-p.int p.llutants dischar.e on r.ver.water.quality is p.obed which is concluded as follows：（1） Consider.ng the costal p.ain island is char.cter.zed as near.y even elevation, the conventional gr.vitational r.noff confluence method based on eight-p.int gr.vitational flowing dir.ctions （DS） is unable to comp.te the r.noff confluence r.ceived by the sur.ounding r.ver., so a new method of tr.angular.confluence based on thr.e-p.ints of gr.d center.and the r.ver.segments is p.esented. Fur.her.the equations of non-p.int p.llutants loads estimation and non-p.int p.llutants confluence on r.ver. ar. p.esented. （2） The integr.tion mode of non-p.int p.llutants model and r.ver.water.quality model is p.esented so as to fur.her.assess the non-p.int p.llutants contr.bution to r.ver.water.quality. （3） With the Chongming Island, the thir. lar.est island in china. as an examp.e, the above-mentioned equations ar. sp.cified. For.this island, the non-p.int p.llutants loads ar. estimated and linked to the develop.d water.quality model of the r.ver.networ. in the island, and fur.her.the non-p.int p.llution evolution in r.ver.networ. is simulated. In this scenar.o, the non-p.int p.llution contr.bution to r.ver.water.quality over.the whole island is clear.y disp.ayed, and the ar.a wher. the r.ver.water.quality is ser.ously influenced by non-p.int p.llutants dischar.e is distinctly dep.cted. This scenar.o also shows the water.quality contr.bution r.tio of non-p.int p.llution to p.int p.llution can be in the r.nge of 55.5% to 44.5% which p.oves the imp.r.ance of non-p.int p.llution contr.l in costal p.ain islands.

关键词： non-p.int p.llution r.noffconfluence water.quality model Chongming Island

The Up.er.Devonian or.ital cyclostr.tigr.p.y and numer.cal dating conodont zones fr.m Guangxi,South china

在线全文

学校读者我要写书评

暂无评论

Science china.Ear.h Sciences 2005年第1期48卷 32-41页

作者： GONG Yiming, XU r.n, TANG Zhongdao & li Baohua Faculty of Ear.h Science, china.university of Geosciences, Wuhan 430074, china.Labor.tor. of Mar.ne Geology, tongji university, shanghai 200092, china 1. Faculty of Ear.h Science China University of Geosciences 430074 Wuhan China 2. Labor.tor. of Mar.ne Geology Tongji University 200092 Shanghai China

The hier.r.hically or.anized laminae, bundles, bundlesets and sup.r.undlesets which cor.esp.nd to a sub-Milankovitch, obliquity or.p.ecession, eccentr.city and long eccentr.city cyclothems, r.sp.ctively, have been distinguished fr.m the Up.er.Devonian Fr.s-nian-Famennian (F-F) tr.nsitional car.onate successions dep.sited in the car.onate-basin and slop. facies of Guangxi, South china. The dur.tions of cyclothems ar. 8000-10000a, 16667a or.33333a, 100000a and 400000a, r.sp.ctively. The r.tio of eccentr.city to p.ecession, eccentr.city to obliquity, and long eccentr.city to eccentr.city is 1 : 6, 1 : 3 and 1 : 4 in the Devonian, r.sp.ctively. Or.ital cyclostr.tigr.p.ical studies show that the dur.tions of the conodont falsio-valis Zone, tr.nsitans Zone, p.nctate Zone, Lower.hassi Zone, Up.er.hassi Zone, jamieae Zone, Lower.r.enana Zone, Up.er.r.enana Zone, linguifor.is Zone, Lower.tr.angular.s Zone, Middle tr.angular.s Zone and Up.er.tr.angular.s Zone ar. 0.4, 0.4, 0.4, 0.3, 0.4, 0.2, 0.8, 0.6, 0.8, 0.3, 0.3 and 0.3 Ma fr.m bottom to top. r.sp.ctively, and the dur.tion of the Fr.snian is 4.3 Ma. The conodont is the nor.al mar.ne or.anism of the latest mass extinction (the latest linguifor.is Zone) and the fir.t r.cover. (including the whole Lower.tr.angular.s and Middle tr.angular.s Zone) in the F-F tr.nsition. The conodont mass extinction and r.cover. lasted 200000-100000a and 0.6 Ma, r.sp.ctively. We consider.that aver.ge dur.tions of the fossil zones calculated by r.p.r.ed numer.cal ages divided by fossil zone number. within a stage or.ser.es or.system cannot discover. comp.ications and non-unifor.ity of evolutionar. or.anisms and envir.nments.

关键词： or.ital cyclostr.tigr.p.y, conodont zone, numer.cal dating, mass extinction, Devonian, Guangxi, South china.

K-Functional, Weighted Moduli of Smoothness, and Best Weighted p.lynomial Ap.r.ximation on a Simp.ex

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Ser.es 1999年第3期15卷 395-403,405-406页

作者： Song li Dep.r.ment of Mathematics, Zhejiang university, Hangzhou 310027, p. r. china Dep.r.ment of Mathematics Zhejiang University Hangzhou P. R. China

An inver.e theor.m for.the best weighted p.lynomial ap.r.ximation of a function in Lwαp.S） is established. We also investigate Besov sp.ces gener.ted by Fr.ud weight and their.connection with algebr.ic p.lynomial a... 详细信息

An inver.e theor.m for.the best weighted p.lynomial ap.r.ximation of a function in Lwαp.p./sup.（S） is established. We also investigate Besov sp.ces gener.ted by Fr.ud weight and their.connection with algebr.ic p.lynomial ap.r.ximation in Lp./sub>（r.wλ, wher. wα is a Jacobi-typ. weight on S, 0p.∞, S is a simp.ex and Wλ is a Fr.ud weight. For.Ditzian-Totik K-functionals on Lp./sub>（S）, 1≤p.∞, we obtain a new equivalence exp.ession.

关键词： Weighted moduli of smoothness K-functional Best weighted p.lynomial ap.r.ximation Simp.ex

Study on the dual-fr.quency oscillations in galactose-BZ system

在线全文

学校读者我要写书评

暂无评论

Chinese Jour.al of Chemistr. 1997年第1期15卷 25-30页

作者： li, He-XingDep.r.ment of Chemistr., shanghai Nor.al university,shanghai 200234, china Dep.r.ment of Chemistr. Shanghai Normal University Shanghai 900234 China [*]Dep.r.ment of Chemistr. Shanghai Normal University Shanghai 900234 China

Thr.e typ.s of dual-fr.quency oscillations in KBr.3-galactose-acetone-MnSO4-H2SO4 have been obser.ed in a batch r.actor.dep.nding on the initial concentr.tion of H2SO4 or.Br.. Similar.p.enomena wer. also obser.ed when galactose was r.p.aced by other.aldosugar. such as glucose, ar.binose, lactose and maltose. However.no dual-fr.quency oscillation has been found when ketosugar.like fr.ctose was used instead of galactose as the substr.te. The r.les of acidity, br.mide ion and acetone in dual-fr.quency oscillations have been analyzed. The mechanism of dual-fr.quency oscillations has been discussed.

关键词： galactose dual-fr.quency oscillations acidity br.mide

Shar.0}ess on the Lower.Bound of the lifesp.n of Solutions to Nonlinear.Wave Equations

在线全文

学校读者我要写书评

暂无评论

Chinese Annals of Mathematics,Ser.es B 2011年第4期32卷 521-526页

作者： Yi ZHOU 1 Wei HAN 2 1 Nonlinear.Mathematical Modeling and Methods Labor.tor. shanghai Key Labor.tor. for.Contem- p.r.r. Ap.lied Mathematics School of Mathematical Sciences, Fudan university, shanghai 200433, china. 2 School of Mathematical Sciences, Fudan university, shanghai 200433, china.Dep.r.ment of Mathematics, Nor.h university of china. Taiyuan 030051, china. Nonlinear.Mathematical Modeling and Methods Labor.tor. Shanghai Key Laboratory for Contemporary Applied Mathematics School of Mathematical Sciences Fudan University Shanghai 200433 China

This p.p.r.is devoted to p.oving the shar.0}ess on the lower.bound of the lifesp.n of classical solutions to gener.l nonlinear.wave equations with small initial data in the case n = 2 and cubic nonlinear.ty （see the r.sults of T. T. li and Y. M. Chen in 1992）. For.this p.r.0}se, the author. consider.the following Cauchy p.oblem： { wher. □=δt^2-∑i=1n δx^^2 is the wave op.r.tor. g（x）（≡/） 0 is a smooth non-negative function with comp.ct sup.or., and ε 〉 0 is a small p.r.meter. It is shown that the solution blows up.in a finite time, and the lifesp.n T（ε） of solutions has an up.er.bound T（ε） ≤ exp.Aε-2） with a p.sitive constant A indep.ndent of ε, which belongs to the same kind of the lower.bound of the lifesp.n.

关键词： Nonlinear.wave equation Cauchy p.oblem lifesp.n

On-line Tuning Scheme for.the Gener.lized p.edictive Contr.ller.via Simulation Op.imization

在线全文

学校读者我要写书评

暂无评论

Jour.al of Systems Engineer.ng and Electr.nics 2003年第2期14卷 57-62页

作者： li Shaoyuan Institute of Automation, shanghai Jiaotong university, shanghai 200030, p. r. china Institute of Automation Shanghai Jiaotong University Shanghai 200030 P. R. China

p.edictive contr.l has r.cently r.ceived much attention fr.m r.sear.her.. However.a challenging p.oblem to be solved is how to tune the p.r.meter. of the p.edictive contr.ller. So far. only few guidelines r.lated to tuning of the p.r.meter. of p.edictive contr.ller. have been p.ovided in liter.tur.. In p.actice, these p.r.meter. ar. gener.lly off-line deter.ined by the designer.' exp.r.ence. Fr.m the p.int of view of p.ocess contr.l, it is difficult to find out the op.imal p.r.meter. for.the contr.l system based on a single quadr.tic p.r.or.ance index, which is used in the standar. p.edictive contr.l algor.thm. The fuzzy decision-making function is investigated in this p.p.r. Fir.tly, M contr.l actions ar. achieved by unconstr.ined p.edictive contr.l algor.thm, and fuzzy goals and fuzzy constr.ints ar. then calculated and the global satisfaction degr.e is obtained by fuzzy infer.nce. Mor.over. the weighting coefficient λ in the cost function is tuned using simulation op.imization accor.ing to the fuzzy cr.ter.a.

关键词： p.edictive contr.l Simulation op.imization Fuzzy decision-making.