检索结果-南通市图书馆

Probing the Impact of Solvent on the Strength of Lewis Acids via Fluorescent Lewis Adducts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Precision Chemistry 2023年第1期1卷 49-56页

作者： amy e.Laturski Joshua R.Gaffen Paul Demay-Drouhard Christopher B.Caputo Thomas Baumgartner Department of Chemistry York UniversityTorontoON M3J 1P3Canada

Various methods have been developed to measure the strength of a Lewis acid.A major challenge for these measurements lies in the complexity that arises from variable solvent interactions and perturbations of Lewis acids as their reaction environment ***,we investigate the impact of solvent effects on Lewis acids for the first time as measured by the fluorescent Lewis adduct(FLA)*** binding of a Lewis acid in various solvents reveals a measurable dichotomy between both polarity and donor ability of the *** not strictly separable,we observe that the influence of solvent polarity on Lewis acid unit(LAU)values is distinctly opposite to the influence of donor *** dichotomy was confirmed by titration data,illustrating that solvation effects can be appropriately and precisely gauged by the FLA method.

关键词： Fluorescence Fluorescent Lewis adducts Lewis acids effective Lewis acidity Solvent polarity Solvent donor strength

The future environmental and health impacts of coal

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

energy Geoscience 2021年第2期2卷 99-112页

作者： Robert B.Finkelman amy Wolfe Michael S.Hendryx University of Texas at Dallas RichardsonTX75080USA University of Kentucky Kentucky Geological SurveyLexingtonKY40506USA Indiana University Bloomington BloomingtonIN47405USA

In the United States,coal consumption in the last 12 years has declined from 1,045,140 million short tons in 2007 to 539,420 million short tons in 2019,a decrease of almost 50%.During that period the number of electric power coal generators has declined from 1,470 to 738 accounting for 21%of *** even more dramatic decrease in coal use has occurred in Western *** significant reduction in coal use and the concomitant closure of coal mines and coal-burning power plants will result in substantially cleaner air,reductions in respiratory problems such as asthma,less heart disease,fewer hospitalizations,and other health benefits,as well as a reduction in occupational health problems such as silicosis and Coal Workers’Pneumoconiosis(Black Lung Disease).However,in China,India,Russia and in several other Asian countries some projections indicate an increase in coal production and *** some situations,the coal is burned in old,highly polluting power *** these regions the health impacts of coal use could *** addition,millions of people in these regions still burn coal in their homes resulting in maximal exposure to the pollutants such as arsenic,selenium,fluorine,and mercury released from coal combustion.

关键词： Coal Combustion Pollutants Human health environment

Quiet in the nest:The nest environment attenuates song in a grassland songbird

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Avian Research 2023年第4期14卷 623-629页

作者： Sarah L.Dobney Mikayla M.K.Bornais D.Ryan Norris amy e.M.Newman Heather Williams Stéphanie M.Doucet Daniel J.Mennill Department of Integrative Biology University of WindsorWindsorOntarioN9B 3P4Canada Department of Integrative Biology University of GuelphGuelphOntarioN1G 2W1Canada Biology Department Williams CollegeWilliamstownMA01267USA

The nest environment may limit the ability of nest-bound birds to hear sounds from the outside *** vocal learning species,such as humans and songbirds,it is vital for young animals to hear the voices of conspecific animals early in *** songbirds,nest structure varies considerably across species,and the resulting impact on sound transmission may have consequences for vocal learning in *** this study,we tested the hypothesis that the nest environment attenuates song of Savannah Sparrows(Passerculus sandwichensis),grassland songbirds that build nests on the ground under cover of dense *** recorded live Savannah Sparrows singing at variable distances from 21 *** recorded songs using one microphone inside the nest(the typical position of a nestling)and another placed 1 m directly above the nest(a typical position of an adult).We found a substantial reduction in signal-to-noise ratio,where songs recorded inside the nest were an average of 11 dB lower than songs recorded directly above the *** estimate that the attenuation imposed by the nest reduced the maximum acoustic environment from 117.7 m(for recordings above the nest),to 78.6 m(for recordings within the nest),which is analogous to listening from a position 39.1 m farther away from the *** research estimated that song transmits up to 100 m in this species,so any adult male within 100 m of a young bird was previously considered a potential vocal *** reducing the nestling acoustic environment from 100 m to 78.6 m,the number of male tutors available to nestlings is reduced by an average of 27%.Given the growing evidence that song learning begins very early in life,future research on vocal development should account for how the structural properties of the natal environment affect the songs that nestlings hear.

关键词： Acoustic environment Nest environment Songbird Sound attenuation Vocal learning

Diel and seasonal patterns of variation in the singing behaviour of Savannah Sparrows (Passerculus sandwichensis)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Avian Research 2019年第3期10卷 336-343页

作者： Ines G.Moran Katrina C.Lukianchuk Stephanie.M.Doucet amy e.M.Newman Heather Williams D.Ryan Norris Daniel J.Mennill Department of Biological Sciences University of WindsorWindsorON N9B3P4Canada Department of Integrative Biology University of GuelphGuelphON N1G2W1Canada Biology Department Williams CollegeWilliamstownMD 01267USA

Background:The vocalizations of birds are dynamic traits that often vary in output with time of day and time of *** quantifying patterns of diel and seasonal variation in vocal output,we can gain insight into the ecology and evolution of birds and the function of their *** this investigation,we quantified diel and seasonal variation in song output by studying a breeding population of Savannah Sparrows (Passerculus sandwichensis).Methods:We used autonomous recorders to collect extensive recordings across the breeding season in a long-term, colour-marked study population of Savannah Sparrows in eastern *** described diel and seasonal variation across five different breeding stages based on recordings of more than 50,000 songs from 34 ***:During the pre-breeding stage, prior to female arrival, males sang a pronounced dawn chorus with a peak in song output during the early *** the breeding stage,in contrast,the dawn chorus was diminished and males instead exhibited a pronounced dusk chorus with a peak in song output during the *** the breeding season,the highest levels of song output occurred in late April and early May,soon after males arrived on the breeding grounds,and the lowest levels occurred in August,prior to the departure of birds for the wintering ***:These patterns suggest that Savannah Sparrows' early-season dawn choruses are directed at males and serve a territorial defense ***-season dusk choruses,in contrast, appear to play a role in attracting mates and possibly acoustic mate guarding.

关键词： Bird song Breeding activities Circadian rhythms Seasonal variation in song

Pink1 and parkindemonstrate multifaceted roles when co-expressed with Foxo

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Advances in Parkinson's Disease 2013年第1期2卷 5-10页

作者： amy M. Todd Brian e. Staveley Department of Biology Memorial University of Newfoundland St. John’s Canada

Pink1 has been linked to both autosomal recessive and sporadic forms of Parkinson disease. The Pink1 protein is thought to be involved in mitochondrial protection by interacting with parkin to prevent oxidative damage, maintain mitochondrial integrity and regulate mitophagy. Pink1 and parkin have been linked to components of the insulin receptor (INR) pathway, including PTeN, Akt and Foxo, but their effects in the INR pathway have been largely overlooked. To further investigate the roles of Pink1/parkin, we have performed co-expression studies to determine the effects Pink1 and parkin on the Foxo-induced phenotype of developmental defects in the Drosophila eye. We examined directed expression of Pink1, parkin, Pink1 or parkin mutants, and Pink1 or parkin interfering RNAs (RNAi) with the overexpression of Foxo in the developing eye of Drosophila. Our findings show that reduction of Pink1 suppresses the effects of Foxo overexpression, where co-overexpression with Pink1 or parkin increases the severity of the phenotype. This suggests that Pink1 and parkin are able to increase the pro-apoptotic effects of Foxo. Contrary to the view that Pink1 and parkin act exclusively as protective proteins in the cell, it is likely that the Pink1/parkin pathway is involved in aspects of cell fate decisions other than degrading toxic proteins and maintaining mitochondrial integrity.

关键词： Pink1 Parkin Foxo Drosophila

Pink1 Rescues Gal4-Induced Developmental Defects in the Drosophilaeye

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Parkinson's Disease 2015年第3期4卷 43-48页

作者： amy M. Todd Brian e. Staveley Department of Biology Memorial University of Newfoundland St. John’s Canada

Parkinson disease pathology often includes the presence of ubiquitin-positive, α-synuclein-enriched inclusions in the remaining neurons. Pink1 (also identified as PARK6) encodes a serinethreonine kinase involved in mitochondrial protection that works with parkin to ubiquitinate various proteins, promoting mitophagy. The parkin protein works to tag cystolic proteins for degradation, and previous work in our laboratory has shown the ability of parkin to rescue a Gal4-induced phenotype. To further investigate the role of Pink1 in protection against toxic proteins, we have performed expression studies to determine the effects of increases and decreases in Pink1 on the Gal4-induced phenotype consisting of developmental defects in the Drosophila eye. Our results show that Pink1 is able to rescue the Gal4-induced phenotype, highlighting a protective role for Pink1 against toxic proteins. When expressing low levels of Gal4, reductions in Pink1 or parkin are not able to induce a phenotype. This suggests that Pink1 or parkin may counter Gal4 effects despite reductions, or that the effects of low level Gal4 may be alleviated by an alternative mechanism. Moreover, the Pink1 mechanism of action during differing types of cell stress, including degradation of toxic proteins, warrants further investigation.

关键词： Drosophila melanogaster Pink1 Parkin Gal4 Toxic Protein Parkinson Disease

Video capsule endoscopy and CT enterography in diagnosing adult hypertrophic pyloric stenosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2013年第37期19卷 6292-6295页

作者： Grigoriy e Gurvits amy Tan Dmitri Volkov Department of Gastroenterology New York University School of Medicine/Langone Medical Center Department of Medicine New York University School of Medicine Department of Anesthesiology New York University School of Medicine/Langone Medical Center

Primary adult hypertrophic pyloric stenosis is a rare but important cause of gastric outlet obstruction that may be misdiagnosed as idiopathic ***,patients present with early satiety,abdominal fullness,nausea,epigastric discomfort and *** gastric retention of a video capsule endoscope is diagnostic in differentiating between the two diseases,in the absence of an organic gastric outlet *** case presents the longest video capsule retention in the medical literature to *** is also the first case report of adult hypertrophic pyloric stenosis diagnosed with video capsule endoscopy or a computed tomography ***,an unusual"plugging"of the gastric outlet with free floating capsule has an augmented effect on disease physiology and on patient’s symptoms.

关键词： Video capsule endoscopy Hypertrophic pyloric stenosis Gastroparesis endoscopy Computed tomography enterography

electricity consumption patterns within cities:application of a data-driven settlement characterization method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Digital earth 2020年第1期13卷 119-135页

作者： Pranab K.Roy Chowdhury Jeanette e.Weaver eric M.Weber Dalton Lunga St.Thomas M.LeDoux amy N.Rose Budhendra L.Bhaduri Urban Dynamics Institute&Geographic Information Science and Technology Group Oak Ridge National LaboratoryOak RidgeTNUSA Bredesen Center For Interdisciplinary Research and Graduate education University of TennesseeKnoxvilleTNUSA

Urban areas presently consume around 75%of global primary energy supply,which is expected to significantly increase in the future due to urban *** sustainable,universal energy access is a pressing challenge for most parts of the *** urban energy consumption patterns may help to address the challenges to urban sustainability and energy ***,urban energy analyses are severely limited by the lack of urban energy *** datasets are virtually non-existent for the developing *** per current projections,most of the new urban growth is bound to occur in these data-starved ***,there is an urgent need of research methods for monitoring and quantifying urban energy utilization ***,we apply a data-driven approach to characterize urban settlements based on their formality,which is then used to assess intraurban urban energy consumption in Johannesburg,South Africa;Sana’a,Yemen;and Ndola,*** is the fastest growing energy *** analyzing the relationship between the settlement types and the corresponding nighttime light emission,a proxy of electricity consumption,we assess the differential electricity consumption *** study presents a simple and scalable solution to fill the present data void to understand intra-city electricity consumption patterns.

关键词： Settlement characterization cities urban electricity consumption VIIRS nighttime lights developing countries

Length-based separation of Bacillus subtilis bacterial populations by viscoelastic microfluidics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microsystems & Nanoengineering 2022年第1期8卷 149-159页

作者： Ping Liu Hangrui Liu Lucie Semenec Dan Yuan Sheng Yan amy K.Cain Ming Li Suqian University Suqian 223800China School of engineering Macquarie UniversitySydneyNSW 2109Australia Department of Physics and Astronomy Macquarie UniversitySydneyNSW 2109Australia ARC Centre of excellence in Synthetic Biology Department of Molecular ScienceMacquarie UniversitySydneyNSW 2109Australia Centre for Regional and Rural Futures Deakin UniversityGeelongVIC 3216Australia Institute for Advanced Study Shenzhen UniversityShenzhen 518060China Biomolecular Discovery Research Centre Macquarie UniversitySydneyNSW 2109Australia

In this study,we demonstrated the label-free continuous separation and enrichment of Bacillus subtilis populations based on length using viscoelastic ***,a gram-positive,rod-shaped bacterium,has been widely used as a model organism and an industrial *** can be arranged in different morphological forms,such as single rods,chains,and clumps,which reflect differences in cell types,phases of growth,genetic variation,and changing environmental *** ability to prepare *** populations with a uniform length is important for basic biological studies and efficient industrial ***,we systematically investigated how flow rate ratio,poly(ethylene oxide)(PeO)concentration,and channel length affected the length-based separation of *** *** lateral positions of *** cells with varying morphologies in a straight rectangular microchannel were found to be dependent on cell length under the co-flow of viscoelastic and Newtonian ***,we evaluated the ability of the viscoelastic microfluidic device to separate the two groups of *** cells by length(i.e.,1-5μm and>5μm)in terms of extraction purity(eP),extraction yield(eY),and enrichment factor(eF)and confirmed that the device could separate heterogeneous populations of bacteria using elasto-inertial effects.

关键词： viscoelastic separation straight