检索结果-南通市图书馆

Anti-leishmanial,immunomodulatory and anti-oxidative activity of quercetin against cutaneous leishmaniasis caused by Leishmania major

引用

Asian Pacific Journal of Tropical Biomedicine 2023年第1期13卷 26-34页

作者： Ahmad Oryan Effat Bemani Somayeh bahrami Department of Pathology School of Veterinary MedicineShiraz UniversityShirazIran Department of Parasitology Faculty of Veterinary MedicineShahid Chamran University of AhvazAhvazIran

Objective:To evaluate the in vitro and in vivo efficacy of quercetin and its immunomodulatory and anti-oxidative activity against Leishmania major(***).Methods:*** promastigotes and amastigotes were incubated with different concentrations of quercetin to estimate EC_(50).For in vivo study,the base of tails of mice was infected with *** developing ulcers in the inoculation site,mice were treated with 50 mg/kg quercetin orally for 28 consecutive *** wound-healing potential of quercetin was evaluated by histopathological analysis of tissue sections stained by hematoxylin and eosin as well as Masson's *** addition,the levels of tumor necrosis factor-α,interleukin-6,malondialdehyde,and adiponectin,the ferric reducing ability of plasma,as well as superoxide dismutase and glutathione peroxidase activities were ***:The EC_(50)values of quercetin against *** promastigotes and intracellular amastigotes were 0.27 and 0.85μM,*** analysis showed that fewer inflammatory cells,more fibroblasts,and more collagen deposition were observed in tissue sections of quercetin-treated *** addition,treatment with quercetin markedly increased glutathione peroxidase activity,the ferric reducing ability of plasma and adiponectin levels while decreasing malondialdehyde,interleukin-6,and tumor necrosis factor-α***:Quercetin shows anti-leishmanial activity,immunomodulatory,anti-oxidative,and anti-inflammatory ***,it may be further explored as an effective drug in treating leishmaniasis.

关键词： Leishmania major Cutaneous leishmaniosis Wound healing Quercetin Immunomodulator

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geochemical indices of soil development on basalt rocks in arid to sub-humid climosequence of Central Iran

引用

Journal of Mountain Science 2020年第7期17卷 1652-1669页

作者： Ahmad HEIDARI alireza RAHEB Soil Science Department College of Agriculture and Natural ResourcesUniversity of TehranKarajP.O.Box 4111Iran

Quantitative weathering indices are efficient tools in determining the soil development from the underlying *** order to evaluate the effects of climate on the soils developed under an arid to sub-humid climosequence in central Iran,twenty soil-development indices were *** samples from six pedons were analyzed for routine physico-chemical and geochemical analyses using X-ray fluorescence(XRF).The lowest and highest calculated soil development indices were observed in the arid and sub-humid regions *** the studied indices,fifteen indices showed similar trends concerning the intensity of *** consistency of such trends reveals the feasibility of using these indices to evaluate basalt weathering rate and soil development in arid,semi-arid and sub-humid *** study demonstrated that,among the evaluated weathering indices,the Weathering Index of Parker(WIP)and mass transfer coefficient(τ)were the most proper indices for predicting basalt weathering *** is due to the fact that these indices use the highly mobile earth elements which are the most sensitive elements in basalt chemical *** calculated indices were subdivided into three subgroups including the ratios of mobile/immobile,mobile/mobile and immobile/mobile elements based on the elements used in their *** state of soil evolution was more accurately predicted compared to the other subgroups using the mobile/immobile subgroup of ***,the weathering indices calculated using the mobile elements are better indicators of weathering intensity,soil formation and the exogenous processes across the arid to sub-humid climosequence.

关键词： Basalt Climosequence Geochemical properties Aridisols Mollisols Inceptisols

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nonlinear buckling and postbuckling behavior of cylindrical shear deformable nanoshells subjected to radial compression including surface free energy effects

引用

Acta Mechanica Solida Sinica 2017年第2期30卷 209-222页

作者： S.Sahmani M.M.Aghdam M.bahrami Department of Mechanical Engineering Amirkabir University of Technology P.O. Box 15875-4413 Tehran Iran

The objective of the present investigation is to predict the nonlinear buckling and postbuckling characteristics of cylindrical shear deformable nanoshells with and without initial imperfection under hydrostatic pressure load in the presence of surface free energy *** this end, Gurtin-Murdoch elasticity theory is implemented into the irst-order shear deformation shell theory to develop a size-dependent shell model which has an excellent capability to take surface free energy effects into account. A linear variation through the shell thickness is assumed for the normal stress component of the bulk to satisfy the equilibrium conditions on the surfaces of nanoshell. On the basis of variational approach and using von Karman-Donnell-type of kinematic nonlinearity, the non-classical governing differential equations are derived. Then a boundary layer theory of shell buckling is employed incorporating the effects of surface free energy in conjunction with nonlinear prebuckling deformations, large delections in the postbuckling domain and initial geometric imperfection. Finally, an eficient solution methodology based on a two-stepped singular perturbation technique is put into use in order to obtain the critical buckling loads and postbuckling equilibrium paths corresponding to various geometric parameters. It is demonstrated that the surface free energy effects cause increases in both the critical buckling pressure and critical end-shortening of a nanoshell made of silicon.

关键词： Nanoscale structures Size effect Nonlinear buckling Surface free energy Boundary layer theory

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A microemulsion method for preparation of thiol-functionalized gold nanoparticles

引用

Particuology 2018年第2期16卷 33-36页

作者： Somayeh Tianimoghadam alireza Salabat Department of Chemistry Faculty of Science Lorestan University 68137-1-7133 Khorramabad Iran Department of Chemistry Faculty of Science Arak University 38156-8-8349 Arak Iran Institue of Nanosciences & Nanotechnolgy Arak University 38156-8-8349 Arak Iran

A new microemulsion method using tetraoctylammonium bromide as a cationic surfactant has been formulated to fabricate thiol-functionalized gold nanoparticles, The nanoparticles were compared with those synthesized by the multistep Brust two-phase *** nanoparticle sizes and size distributions fabricated by the two methods were characterized by UV-vis ahsorbance spectroscopy and transmittance electron microscopy. The simple microemulsion method produced the same results as those obtained by the Brust method,

关键词： Gold nanoparticles Brust method Microemulsion Thiol-functionalized gold

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ultrasonic irradiation and solvent effects on destabilization of colloidal suspensions of platinum nanoparticles

引用

Particuology 2014年第6期12卷 145-148页

作者： alireza Salabat Shima Soleimani Department of Chemistry Faculty of ScienceArak University

In this work,ultrasonic irradiation and destabilizer solvent were used for destabilizing colloidal platinum *** stabilized platinum nanoparticles were prepared in w/o microemulsion systems composed of sodium bis-（2-ethylhexyl） sulfosuccinate（AOT） and four different solvents,namely,cyclohexane,n-hexane,n-heptane,and *** recovery process of Pt nanoparticles from the colloidal systems was performed by exposing the colloidal samples to ultrasonic irradiation and applying various destabilizing *** of UV-visible spectra confirms that the quantity of Pt nanoparticles removed from the suspension depends on the length of time of the ultrasonic irradiation and the nature of the microemulsion oil phase.A critical time for the ultrasonic irradiation has been introduced for the phase separation of colloidal *** perform the solvent study,four destabilizer solvents,namely,dioxane,ethyl acetate,diethyl ether,and tetrahydrofuran,were used for breaking the colloidal suspension of platinum *** on the ’good solvent’ and ’poor solvent’ idea,it is verified that the effect of the destabilizer solvents on the aggregation process follows the following order：tetrahydrofuran 〉 ethyl acetate 〉dioxane〉 diethyl ether.

关键词： Colloid destabilization Ultrasonic irradiation Microemulsion Solvent effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Functional roles of lncRNAs in the pathogenesis and progression of cancer

引用

Genes & Diseases 2021年第4期8卷 424-437页

作者： alireza Ahadi Department of Medical Genetics School of MedicineShahid Beheshti University of Medical SciencesTehran198396-3113Iran

Long noncoding RNAs(lncRNAs)act as regulators of gene expression and pivotal transcriptional regulators in cancer cells via diverse *** involves a variety of pathological and biological activities,such as apoptosis,cell proliferation,metastasis,and *** using microarray and RNA sequencing,it was identified that dysregulation of lncRNAs affects the tumorigenesis *** together,these lncRNAs are putative biomarker and therapeutic target in human *** this review,I discuss the latest finding regarding the dysregulation of some important lncRNAs and their diverse mechanisms of these lncRNAs in the pathogenesis and progression of certain cancers;also,I summarize the possible roles of lncRNAs in clinical application for diagnosis and prognosis of cancer.

关键词： Biomarker Cancer Dysregulation LncRNA NcRNA

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Modeling flame propagation speed and quenching distance of aluminum dust flame with spatially random distribution of particles

引用

Journal of Central South University 2017年第1期24卷 81-89页

作者： Mehdi Bidabadi alireza Khoeini Poorfar Combustion Research Laboratory School of Mechanical EngineeringIran University of Science and Technology(IUST)Narmak16846-13114TehranIran

In this research combustion of aluminum dust particles in a quiescent medium with spatially discrete sources distributed in a random way was studied by a numerical approach.A new thermal model was generated to estimate flame propagation speed in a lean/rich reaction *** speed for different particle diameters and the effects of various oxidizers such as carbon dioxide and oxygen on flame speed were *** was considered the inert *** addition,the quenching distance and the minimum ignition energy(MIE) were studied as a function of dust *** burning time models for aluminum were employed and their results were compared with each *** model was based on conduction heat transfer mechanism using the heat point source *** combustion of single-particle was first studied and the solution was *** the dust combustion was investigated using the superposition principle to include the effects of surrounding *** is found that larger particles have higher values of quenching distance in comparison with smaller particles in an assumed dust *** the increase of dust concentration the value of MIE would be decreased for an assumed particle *** random discrete heat sources method,the obtained results of random distribution of fuel particles in space provide closer and realistic predictions of the combustion physics of aluminum dust flame as compared with the experimental findings.

关键词： flame propagation speed random particle distribution quenching distance random discrete combustion aluminum

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Parametric computational study on butterfly-shaped hysteretic dampers

引用

Frontiers of Structural and Civil Engineering 2019年第5期13卷 1214-1226页

作者： alireza FARZAMPOUR Matthew Roy EATHERTON Department of Civil and Environmental Engineering Virginia TechBlacksburgVA 24060USA

A parametric computational study is conducted to investigate the shear yielding, flexural yielding, and lateral torsional buckling limit states for butterfly-shaped links. After validating the accuracy of the finite element modeling approach against previous experiments, 112 computational models with different geometrical properties were constructed and analyzed including consideration of initial imperfections. The resulting yielding moment, corresponding critical shear force, the accumulation of plastic strains through the length of links as well as the amount of energy dissipated are investigated. The results indicate that as the shape of the butterfly-shaped links become too straight or conversely too narrow in the middle, peak accumulated plastic strains increase. The significant effect of plate thickness on the buckling limit state is examined in this study. Results show that overstrength for these links (peak force divided by yield force) is between 1.2 and 4.5, with straight links producing larger overstrength. Additionally, proportioning the links to delay buckling, and designing the links to yield in the flexural mode are shown to improve energy dissipation.

关键词： structural fuse hystcretic damper finite element analysis energy dissipation initial imperfection butterfly-shaped links

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Prediction of Seaward Slope Recession in Berm Breakwaters Using M5＇ Machine Learning Approach

引用

China Ocean Engineering 2016年第1期30卷 19-32页

作者： alireza Sadat HOSSEINI Mehdi SHAFIEEFAR Faculty of Civil and Environmental Engineering Tarbiat Modares University Tehran Iran

In the design process of berm breakwaters, their front slope recession has an inevitable rule in large number of model tests, and this parameter being studied. This research draws its data from Moghim＇s and Shekari＇s experiment results. These experiments consist of two different 2D model tests in two wave flumes, in which the berm recession to different sea state and structural parameters have been studied. Irregular waves with a JONSWAP spectrum were used in both test series. A total of 412 test results were used to cover the impact of sea state conditions such as wave height, wave period, storm duration and water depth at the toe of the structure, and structural parameters such as berm elevation from still water level, berm width and stone diameter on berm recession parameters. In this paper, a new set of equations for berm recession is derived using the M5＇ model tree as a machine learning approach. A comparison is made between the estimations by the new formula and the formulae recently given by other researchers to show the preference of new M5＇ approach.

关键词： berm breakwater recession experimental data M5' model tree machine learning method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Delta-doped quantum wire tunnel junction for highly concentrated solar cells

引用

Chinese Physics B 2019年第4期28卷 275-279页

作者： Ali bahrami Mahyar Dehdast Shahram Mohammadnejad Habib Badri Ghavifekr Optoelectronics and Nanophotonics Research Laboratory (ONRL) Electrical and Electronics Engineering DepartmentSahand University of Technology Nanoptronics Research Center Electrical and Electronics Engineering DepartmentIran University of Science and Technology Microelectronics Research Laboratory Department of Electrical Engineering Sahand University of Technology

We propose a novel structure for tunnel junction based on delta-doped AlGaAs/GaAs quantum wires. Higher spatial confinement of quantum wires alongside the increased effective doping concentration in the delta-doped regions extremely increase the peak tunneling current and enhance the performance of tunnel junction. The proposed structure can be used as tunnel junction in the multijunction solar cells under the highest possible thermodynamically limited solar *** combination of the quantum wire with the delta-doped structure can be of benefit to the solar cells' advantages including higher number of sub-bands and high degeneracy. Simulation results show a voltage drop of 40 mV due to the proposed tunnel junction used in a multijunction solar cell which presents an extremely low resistance to the achieved peak tunneling current.

关键词： delta-doping quantum wire solar cell tunnel junction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：