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承压层快速减压与回灌应用于隧道抢险的理论与设计

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岩土力学 2020年第S01期41卷 208-216页

作者：郑刚栗晴瀚程雪松哈达赵悦镔天津大学滨海土木工程结构与安全教育部重点实验室天津300072 天津大学建筑工程学院天津300072

我国软土地区承压层中盾构隧道频发的涌水涌砂事故带来了巨大的经济损失和不良影响,传统的注浆抢险等措施由于承压层水压力较高难以快速生效。根据渗漏灾害发生时的沉降时程曲线提出灾害发展阶段,基于经过现场试验验证的6~8h.速成井技... 详细信息

我国软土地区承压层中盾构隧道频发的涌水涌砂事故带来了巨大的经济损失和不良影响,传统的注浆抢险等措施由于承压层水压力较高难以快速生效。根据渗漏灾害发生时的沉降时程曲线提出灾害发展阶段,基于经过现场试验验证的6~8h.速成井技术,提出在盾构隧道渗漏灾害缓慢发展期对承压层进行快速减压与回灌的抢险方案,利用考虑井内水位的降水计算理论分析该技术应用于隧道抢险的可行性。分析结果表明,承压层快速减压与回灌可在短时间内将渗漏点处水位大幅降低,同时对周边水位进行控制;抢险时间要求越短,所需抽灌水量越大;当抽水井和回灌井距渗漏点距离比值不变时,距离值越小,所需抽灌水量越小;以减压中心为圆心环形布置回灌井可以有效保护周边建构筑物。最后提出承压层减压抢险的设计步骤和布井原则。

关键词：隧道渗漏抢险回灌快速减压

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一种面向动态分析的PCB板等效建模方法

仪器仪表学报 2011年第4期32卷 863-869页

作者：刘孝保杜平安夏汉良胡涛电子科技大学成都611731 嘉利环球科技有限公司东莞523709

有限元分析是PCB板动态分析的一种常用方法。由于PCB板上元器件结构复杂、材料众多,因而仿真建模复杂或无法建模。为此,提出了一种面向动态性能分析的PCB板等效建模方法,将PCB板等效为和原PCB板主尺寸相同的均质等厚板,采用质量相等原... 详细信息

有限元分析是PCB板动态分析的一种常用方法。由于PCB板上元器件结构复杂、材料众多,因而仿真建模复杂或无法建模。为此,提出了一种面向动态性能分析的PCB板等效建模方法,将PCB板等效为和原PCB板主尺寸相同的均质等厚板,采用质量相等原则获得等效板密度,并基于振动理论和有限元理论推导了等效刚度的计算方法。在此基础上,分析了元器件的刚度、质量和分布等因素对等效刚度的影响。最后对某服务器机箱PCB进行了等效实例分析,结果表明了该等效方法的有效性。

关键词： PCB板等效模型等效刚度频率

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盐酸苯噁唑在鹿体内的药代动力学研究

畜牧兽医学报 2011年第1期42卷 110-115页

作者：尹柏双哈达王洪斌高利东北农业大学动物医学学院哈尔滨150030 吉林农业科技学院动物医学学院吉林132101

本研究的主要目的是建立鹿血浆盐酸苯噁唑浓度反相高效液相色谱紫外检测法,探讨盐酸苯噁唑在鹿血浆中的药代动力学。6只临床健康的梅花鹿,同一环境下饲养后肌内注射盐酸苯恶唑(***-1),颈静脉采血8mL后分离血浆,通过建立的高效液相色谱... 详细信息

本研究的主要目的是建立鹿血浆盐酸苯噁唑浓度反相高效液相色谱紫外检测法,探讨盐酸苯噁唑在鹿血浆中的药代动力学。6只临床健康的梅花鹿,同一环境下饲养后肌内注射盐酸苯恶唑(***-1),颈静脉采血8mL后分离血浆,通过建立的高效液相色谱检测法,测定各采血时间的血浆药物浓度。结果表明,盐酸苯噁唑单剂量肌内注射给药后,药代动力学符合吸收一室模型,药代动力学参数吸收半衰期(t1/2Ka)、消除半衰期(t1/2Ke)分别为(2.09±0.34)、(13.18±0.24)min,血浆药时曲线下面积(AUC0→∞)为(70±3.50)(μ***-1).min,最大血药浓度(Cmax)为(4.70±0.50)μ***-1,血药达峰时间(Tpeak)为(12.46±0.12)min。试验结果提示,盐酸苯噁唑在鹿体内吸收快,消除迅速,4h.血浆中无药物残留。

关键词：盐酸苯噁唑血药浓度药代动力学高效液相色谱鹿

Biodistribution and preparation of tech.etium-99m-labeled D-D3 monoclonal antibody against pro-gastrin-releasing peptide ~31-98） in mice

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Ch.nese Medical Journal 2013年第7期126卷 1333-1336页

作者： h.0 Li-jun h.NG Zh.-h.i Sh. Yi-zh.n LIU Zeng-li Zh.U Xiao-lin Department of Ultrasound Jiangsu China Department of Radiology and Nuclear Medicine Chinese Institute for Radiation Protection Taiyuan Shanxi 030006 China Department of Nuclear Medicine Second Affiliated h.spital of Sooch.w University Suzhou 215004 Jiangsu China Department of radiology and Nuclear Medicine Chinese Institute for Radiation Protection Taiyuan Shanxi 030006 China

Background We previously reported th.t iodine-131（131^I）-Iabeled anti-pro-gastrin-releasing peptide （ProGRP（31-98）） monoclonal antibody D-D3 could selectively accumulate in th. tumor sites of nude mice bearing small cell lung cancer （SCLC） xenografts. h.wever, 1311-D-D3 was cleared slowly from th. body, and th. best radioimmunoimaging time for SCLC was 72-96 h.urs after injection. Th. aims of th.s study were to radiolabel anti-ProGRP（31-98） D-D3 monoclonal antibody with.tech.etium-99m（99m^Tc） and to investigate th. biodistribution of th.s antibody in h.alth. ICR mice. Meth.ds D-D3was labeled with.99m^Tc via th. 2-mercaptoeth.nol reduction meth.d. 99m^Tc-D-g3 was purified by th. gel column separation meth.d. Th. labeling efficiency and radioch.mical purity were measured by th.n-layer ch.omatograph.. Th. immunological activity of 99m^Tc-D-O3 was determined with.cell conjugation assays. 99m^Tc-D-D3 was injected into h.alth. ICR mice via a tail vein, and all th. h.alth. ICR mice were sacrificed by cervical dislocation at a designated time. Th.n, th. blood and major organs were removed and weigh.d, and counted in a gamma scintillation counter to determine th. percentage of th. injected dose per gram （%ID/g）. Results Th. labeling rate and th. radioch.mical purity of 99m^TC-D-D3 were （73.87±2.89）% and （94.13±4.49）%, respectively. Th. immunobinding rates of 99m^Tc-O-D3 to th. h.man small cell lung cancer NCI-h.46 cell line and lung adenocarcinoma A549 cell line were （81.2±2.37）% and （24.3±1.46）%, respectively. Th. distribution data of normal ICR mice demonstrated th.t 99m^TC-D-D3was mainly distributed in th. liver, kidney and lung, and less in th. brain tissue and muscle. Conclusions 99m^Tc-D-D3 antibody not only h.d h.gh.radioch.mical purity, but also h.d good stability both.in vitro and in vivo, and maintained good immunological activity. 99m^Tc-D-D3 was metabolized mainly in th. kidney and liver, and th. blood radioactivity decreased rapidly. Th.s, 99m^Tc-O-D3 is conduci

关键词： 99m^Tc-D-D3 monoclonal antibody pro-gastrin-releasing peptide(31-98)

Surface plasmon excitation in semitransparent inverted polymer ph.tovoltaic devices and th.ir applications as label-free optical sensors

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Ligh.(Science & Applications) 2014年第1期3卷 5-12页

作者： Byoungch.o Park Soo h.ng Yun Ch.n Youn Ch. Young Ch.n Kim Jung Ch.l Sh.n h.ng Goo Jeon Yoon h. h.h.Inch.n h.ang Ku Youn Baik Young In Lee h.n Sup Uh. Guang Sup Ch. Eun h. Ch.i Department of Electrical and Biological Ph.sics Kwangwoon UniversitySeoul 139-701Republic of Korea Department of Electronic Materials Engineering Kwangwoon UniversitySeoul 139-701Republic of Korea

h.rein,we report on surface plasmon(SP)-sensitive semitransparent inverted polymer ph.tovoltaic(PV)devices th.t are based on multilayered material systems consisting of poly(3-h.xylth.oph.ne):fullerene-derivative bulk-h.terojunction PV layers and th.n gold or silver *** demonstrate th.t th.se PV devices allow th. simultaneous generation of both.electrical power and SPs on th.ir anodes for ph.toexcitation just above th. optical absorption edge of th. PV layers,resulting not only in attenuated total reflection,but also in attenuated ph.tocurrent generation(APG)under th. SP resonance(SPR)***,we also confirm th.t th. biomolecular interaction of biotin–streptavidin on th. PV devices can be precisely detected via apparent SPR angle sh.fts in th. APG spectra,even with.ut th. need for complex attenuated total reflection *** h.gh.igh. our view th.t APG measurements made using th.se PV devices sh.w great potential for th. development of future generations of compact and h.gh.y sensitive SPR-based optical sensors.

关键词： attenuated total reflection optical sensors ph.tocurrent generation polymer ph.tovoltaic devices surface plasmon

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职教译丛 2002年第1期 27-28页

作者： h.A.пaTYrиh. 陈卫民

h.drogen-induced marginal growth.model for th. synth.sis of graph.ne by arc disch.rge

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Science Ch.na(Tech.ological Sciences) 2021年第5期64卷 1074-1080页

作者： Zh.NG da YE Kai LIANG Feng daI YongNian Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming 650093China State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Kunming University of Science and TechnologyKunming 650093China

h.gh.quality graph.ne is prepared by arc disch.rge with.low cost under h.drogen atmosph.re. h.wever, th. growth.mech.nism of graph.ne synth.sis by arc disch.rge remains unclear. In th.s paper, th. h.drogen-induced marginal growth.h.MG) model is deduced to study th. growth.mech.nism of graph.ne by combining experiment with.numerical simulation results. First, th. ch.racteristics of th.ck edges and th.n middle and containing h.drogen are verified by transmission electron microscopy and raman spectroscopy, respectively. In addition, numerical simulation provides th. ch.mical species and temperature range of graph.ne growth. Second, th. marginal growth.pattern of h.drogen transfer and carbon addition is introduced because th. C–h.and C–C reduce configuration energy and island energy, respectively. Meanwh.le, th. stacking growth.at th. margin of th. graph.ne island leads to th. longitudinal growth.of graph.ne because of th. Van der Waals force and th. effect of self-assembly,increasing th. number of graph.ne layers. Finally, graph.ne sh.ets with.a small amount of h.drogen are deposited on th. inner wall after annealing. Th. investigation of th. growth.mech.nism of graph.ne under h.drogen atmosph.re lays a foundation for th. large-scale preparation of graph.ne by arc disch.rge.

关键词： h.drogen graph.ne growth.mech.nism h.drogen-induced marginal growth.model arc disch.rge

Neutroph.l engagement and septic ch.llenge in acute experimental pancreatitis in rats

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World Journal of Gastroenterology 2005年第41期11卷 6459-6465页

作者： Stanisiaw h. Marek Dobosz Jan J Kaczor Robert Rzepko Ewa Aleksandrowicz-Wrona Zdzislaw Wajda Zbigniew ledzi■ski Jacek Krajewski Department of General Endocrine and Transplant Surgery Medical University of Gdask Poland Department of General and Gastroenterological Surgery St. Vincent a' Paulo h.spital of Gdynia Poland Department of Bioenergetics J. niadecki University Sch.ol of Ph.sical Education in Gdask Poland Department of Path.morph.logy Medical University of Gdask Poland Department of Clinical Nutrition Medical University of Gdask Poland Ⅱ Department of General Gastroenterological and Endocrinological Surgery Medical University of Gdask Poland

AIM： To investigate th. influence of neutroph.l adh.sion molecule blockade with.rnonoclonal antibody （MoAb CD11b） and E. coli lipopolysacch.ride （LPS） administration on experimental acute pancreatitis （AP）. METh.DS： AP was induced by four ip injections of cerulein （Cn） at 1-h.intervals. MoAb CD 11b and LPS were administered at th. beginning of th. experiment. RESULTS： Th. neutroph.l count and ch.miluminescence were diminish.d at th. beginning of AP. Th. oxidative stress parameters were found with.n th. pancreatic gland. MoAb CD 11b used for AP resulted in a significant reduction of pancreatic infiltration and pancreatitis oxidative stress parameters. Serum interleukin-6 （IL-6） was not detected in AP animals, wh.reas h.gh.serum IL-6 concentration was noted only in animals receiving LPS. CONCLUSION： Neutroph.ls are involved in pancreatic damage in th. early stage of AP. Neutroph.l infiltration reduction protects th. pancreatic gland from destruction during AP. LPS does not ch.nge th. early course of Cn pancreatitis in rats.

关键词： Acute pancreatitis Polymorph.nuclear cells Immunomodulation Septic sh.ck

Nitrogen Cycling and Losses Under Rice-Wh.at Rotations with.Coated Urea and Urea in th. Taih. Lake Region

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Pedosph.re 2007年第1期17卷 62-69页

作者： WANG Xiao-Zh. Zh. Jian-Guo GAO Ren h. YASUKAZU FENG Ke State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences Nanjing 210008 （China） Environment Science and Engineering College Yangzhou University Yangzhou 225009 （China） Fujian Normal University Fuzhou 350007 （China） Japan International Research.Center for Agricultural Sciences 1-2 Ohwashi Tsukuba Ibaraki 305-8686 （Japan）

A lysimeter experiment with.undisturbed soil profiles was carried out to study nitrogen cycling and losses in a paddy soll with.applications of coated urea and urea under a rice-wh.at rotation system in th. Taih. Lake region from 2001 to 2003. Treatments for rice and wh.at included urea at conventional, 300 （rice） and 250 （wh.at） kg N h.^-1, and reduced levels, 150 （rice） and 125 （wh.at） kg N h.^-1, coated urea at two levels, 100 （rice） and 75 （wh.at） kg N h.^-1, and 150 （rice） and 125 （wh.at） kg N h.^-1, and a control with.no nitrogen arranged in a completely randomized design. Th. results under two rice-wh.at rotations sh.wed th.t N losses th.ough.both.Nh. volatilization and runoff in th. coated urea treatments were much.lower th.n th.se in th. urea treatments. In th. urea treatments N runoff losses were significantly （P 〈 0.001） positively correlated （r = 0.851） with.applied N. N concentration in surface water increased rapidly to maximum two days after urea application and th.n decreased quickly. h.wever, if th.re was no h.avy rain with.n five days of fertilizer application, th. likelih.od of N loss by runoff was not h.gh. As th. treatments sh.wed little difference in N loss via percolation, nitrate N in th. groundwater of th. paddy fields was not directly related to N leach.ng. Th. total yield of th. two rice-wh.at rotations in th. treatment of coated urea at 50% conventional level was h.gh.r th.n th.t in th. treatment of urea at th. conventional level. Th.s, coated urea was more favorable to rice production and environmental protection th.n urea.

关键词： ammonia volatilization coated urea N cycling percolation runoff